KEGG   Caretta caretta (Loggerhead turtle): 125640618
Entry
125640618         CDS       T09292                                 
Symbol
PLCB3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ccay  Caretta caretta (Loggerhead turtle)
Pathway
ccay00562  Inositol phosphate metabolism
ccay01100  Metabolic pathways
ccay04020  Calcium signaling pathway
ccay04070  Phosphatidylinositol signaling system
ccay04081  Hormone signaling
ccay04082  Neuroactive ligand signaling
ccay04261  Adrenergic signaling in cardiomyocytes
ccay04270  Vascular smooth muscle contraction
ccay04310  Wnt signaling pathway
ccay04371  Apelin signaling pathway
ccay04540  Gap junction
ccay04621  NOD-like receptor signaling pathway
ccay04912  GnRH signaling pathway
ccay04916  Melanogenesis
Module
ccay_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ccay00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    125640618 (PLCB3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    125640618 (PLCB3)
   04371 Apelin signaling pathway
    125640618 (PLCB3)
   04020 Calcium signaling pathway
    125640618 (PLCB3)
   04070 Phosphatidylinositol signaling system
    125640618 (PLCB3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    125640618 (PLCB3)
   04081 Hormone signaling
    125640618 (PLCB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    125640618 (PLCB3)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    125640618 (PLCB3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    125640618 (PLCB3)
   04916 Melanogenesis
    125640618 (PLCB3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    125640618 (PLCB3)
   04270 Vascular smooth muscle contraction
    125640618 (PLCB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ccay04131]
    125640618 (PLCB3)
Enzymes [BR:ccay01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     125640618 (PLCB3)
Membrane trafficking [BR:ccay04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    125640618 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    125640618 (PLCB3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 125640618
NCBI-ProteinID: XP_048715361
Position
7
AA seq 1209 aa
MAGARPGVHALQLEPLRVPETLIRGSKFIKWDEEPTTQTLVTLRVDPLGFFLYWNAPHME
VDILDISSIRDTRTGRYARIPKDPKLREMLGLGGSEPRPEENLLTVVHGPDLVNISFLNF
MAVQEDVAKVWTEELFKLAMNILAQNASRNTFLQKTYTRLKLQVNQESRIPVKNILKMFS
ADKKRVETALESCGLNFNRSESIKPDEFTLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LSLDQLMDFINQRQRDPRLNEVLYPPLSCAQVRQLIDKYEPNRQFLERDQMSMEGFGPLP
RGEENSIVPPEKLDLSDDMSQPLSSYFINSSHNTYLTAGQLTGNSSVEMYRQVLLSGCRC
IELDCWKGRPQDEEPFITHGFTMTTEIPFKEVIEAIAESAFKTSPFPVILSFENHVDSAK
QQAKMAEYCRSIFGDALLIDPLEKYPLQPGVVLPSPQELMGRILVKNKKRRQRRASKGPE
GSSIRKRLLESTVSDAGPGLVDLPSPPPGSPYVEQHKGATPPVIANGEEKAPPERLAKLA
EPRKSIDREADSEEEEEEEQPDPKKPTTDEGTASSEVNATEEMSTLVNYIEPVKFKSFQA
ASKRDKSFEMSSFVETKGLEQLTKSPMEFVEYNKKQLSRIYPKGTRVDSSNYMPQLFWNA
GCQMVALNFQSLDLPMQLNLGMFEYNRRSGYLLKPEFMRREDKPFDPFTENIVDGIVANM
VKVKIISGQFLSDKRVGIYVEVDMFGLPVDTKRKFRTRPSQGNSFNPVWDEEPFVFPKVV
LPTLASLRIAVFEEGGKFVGHRILPVSAIRSGYHYICLRSESNQPLSLPALLVYTEANDY
IPDDHQDYAEALINPIKHVSLMDQRAKQLVALIGDSEENSEKPRETSGKQRADVVAEPPT
DSRQPPTVLLPPAGSPSVASPGQRDDLIASVLAEVAPQSLEELRQQKGYIKLLKKQYREL
KELRKKHMKNISSLNKKQSTQAHQLHSDSLRRRSQVERSLRRGHQDANGSLEALEQEVSR
QKLELQEGQLRGLLQLRETQHQVERARKKEHLQQAQQRLREIAQDCQAAQLKRVKETSER
EKKELQKILDRKRHNSITEAKSREKQKKDVELTEINRRHINESVNSIRRLEEAQKRRQEK
LVSGHQEILQQIEEEEPRLVEELERECELEAQALPQEIRCFLQAELEVGVRNGHPRAAPQ
EEEDESTVL
NT seq 3630 nt   +upstreamnt  +downstreamnt
atggccggggcgcgcccgggggtccacgcgctgcaactggagccgctgcgggtccccgag
accctgatccggggcagcaagttcatcaaatgggacgaggagccaacaacccagaccctg
gtgacgctgcgggttgaccccttgggattcttcctctactggaacgcaccccacatggaa
gttgacatcttggacatcagctccattcgagacacgcggactgggcgctatgccagaatt
ccaaaggaccccaagttgcgggagatgctgggattggggggctcagagccgcggcccgag
gagaacctgctgactgtggtgcatggcccggacctcgtcaacatcagcttcctgaacttc
atggcagtccaggaggacgtggccaaggtctggactgaggagctgttcaaactggctatg
aacattctggcccaaaatgcgtctcgcaacaccttcctgcagaaaacctacacccggctc
aaactccaggtgaaccaggagagccggatcccagtgaagaacatcctgaagatgttctcg
gccgataagaagcgtgtggagacagctctggagtcctgtggccttaacttcaatcggagc
gagtcaatcaagccagacgagttcaccctggagatctttgagcgcttcctgaacaagctc
tgtctgcggcctgacattgacaaaatcctgctggagattggggcgaaggggaaaccctac
ctgagcctggatcagctgatggatttcatcaaccagcggcagcgggacccacggctgaat
gaggtgctataccccccccttagctgtgcccaggtgcgccagctgatcgacaagtacgag
cccaaccgccagttcctggagcgtgaccagatgtccatggaggggttcgggccgctacct
cggggggaggagaacagcatcgtcccccctgaaaagctggacctgagcgacgacatgagc
cagccactgagcagctacttcatcaactcctcccacaacacctacctcacagcgggccag
ctgacggggaactcctcggtggagatgtatcgccaggtgctgctgagtggctgccgctgc
atcgaacttgactgctggaaggggcggccccaggacgaagagcccttcatcacgcacggc
ttcaccatgacaaccgagatccctttcaaggaggtgattgaggccattgctgaaagcgct
ttcaagacctccccgttccctgtcatcctgtcctttgagaaccatgttgactcggccaag
cagcaggcaaagatggccgagtactgccgcagcatctttggcgatgcactactgatcgat
cccctagagaaatacccgctgcaaccaggcgtggtactgcccagcccccaggagctgatg
ggccgcatcctggtgaagaacaagaagcggcggcagcggcgggcgagcaagggccccgag
gggagcagcatccgcaagcgcctgctggagtccaccgtgagcgatgcggggccaggcctt
gtggatttgccctcgccccctccgggctccccttatgtcgagcagcacaagggggccacc
cctccggtcattgccaatggggaggagaaggcgccaccggagagactggccaagctggca
gagccccgtaaatccattgaccgggaagctgacagcgaagaggaggaggaggaagagcag
ccagatcccaagaagcccacaacagatgagggcacggccagcagtgaggtgaatgccacc
gaagaaatgtccacactggtgaattacattgaacccgtcaaattcaaatccttccaggcc
gccagcaagcgggacaagtccttcgagatgtcgtccttcgtggagaccaaggggctggag
cagctcaccaagagccccatggaatttgtcgaatacaacaagaagcagctaagccgcatc
taccccaagggcacacgggtcgactcctccaattacatgccccagcttttctggaacgct
ggctgccagatggtggcactcaacttccagtccctcgacctgccaatgcagctgaacctg
ggcatgtttgagtacaaccggcgcagtgggtacctgctgaagcccgagttcatgcggcgt
gaggacaagccctttgaccccttcactgagaacatcgtggatggcattgtggccaacatg
gtcaaggtcaagataatttcggggcagttcttgtcagacaagcgggtgggcatctacgtg
gaagtagacatgttcggtctccccgtcgacaccaagcgcaagttccggacgcgcccgtcc
caggggaactccttcaaccccgtctgggatgaggagcccttcgttttccccaaggtggtg
ctgcccacgctggcgtccctgcgcattgctgtctttgaggagggaggtaaatttgtcggg
caccggatcctgcctgtctcagccatccggtccgggtaccactacatctgcctgcgcagt
gagagcaaccagcctctgagcctgcccgccctgctggtctacacagaagccaatgactat
atcccagatgaccaccaggactacgcagaggccctgatcaaccccattaaacacgtcagc
ctcatggaccagcgggcaaaacagctggtggcactgattggagacagtgaagagaattca
gagaagccgcgggaaacgtctgggaagcagcgagctgatgtggtggccgagccccccacg
gattcccgacagccgcccactgtcctgctgccccctgccggcagccctagtgtcgccagc
ccagggcaaagggatgacctcattgctagcgtcctcgcagaggtggctccccagtccctg
gaggagctgcggcagcaaaagggctacatcaagctgctgaagaagcagtaccgggagctg
aaggagctacgcaagaagcacatgaagaacatctccagcctcaacaagaagcagagcacc
caggctcaccagctgcacagcgacagcctccggcgccgctcccaagtggaacggagcctg
cgccgtgggcaccaggatgccaacggctcactggaggcactggagcaggaagtgtctcgg
cagaagctggagctgcaggaggggcagctgcggggactgctgcagctgcgggaaacccag
caccaggtggagagagcccgcaaaaaggagcacctgcaacaggcccagcagcggctgcgg
gaaattgcccaggactgccaggctgcccagctgaagagagtcaaggagaccagtgagagg
gagaagaaggagctgcagaaaatcctggaccgcaagcggcacaacagcatcacagaggcc
aaatcccgggagaagcagaagaaagatgtggagctgactgagattaacaggagacacatc
aacgaatcagtgaattccatccgcaggctggaggaagcccagaagcggcgccaggagaag
cttgtgtcggggcaccaggaaatcctacagcaaattgaagaggaggagcccaggctggtg
gaggagttggagcgggagtgcgagctggaggcacaggcactgccccaggagatccgctgc
ttcctccaagctgagctggaggtgggggtgagaaatgggcacccccgggctgcccctcag
gaagaggaggatgagagcactgtgctgtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (13)   

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