KEGG   Cinclus cinclus (white-throated dipper): 134045843
Entry
134045843         CDS       T10813                                 
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ccic  Cinclus cinclus (white-throated dipper)
Pathway
ccic00562  Inositol phosphate metabolism
ccic01100  Metabolic pathways
ccic04020  Calcium signaling pathway
ccic04070  Phosphatidylinositol signaling system
ccic04081  Hormone signaling
ccic04082  Neuroactive ligand signaling
ccic04261  Adrenergic signaling in cardiomyocytes
ccic04270  Vascular smooth muscle contraction
ccic04310  Wnt signaling pathway
ccic04371  Apelin signaling pathway
ccic04540  Gap junction
ccic04621  NOD-like receptor signaling pathway
ccic04912  GnRH signaling pathway
ccic04916  Melanogenesis
Module
ccic_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ccic00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    134045843 (PLCB2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    134045843 (PLCB2)
   04371 Apelin signaling pathway
    134045843 (PLCB2)
   04020 Calcium signaling pathway
    134045843 (PLCB2)
   04070 Phosphatidylinositol signaling system
    134045843 (PLCB2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    134045843 (PLCB2)
   04081 Hormone signaling
    134045843 (PLCB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    134045843 (PLCB2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    134045843 (PLCB2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    134045843 (PLCB2)
   04916 Melanogenesis
    134045843 (PLCB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    134045843 (PLCB2)
   04270 Vascular smooth muscle contraction
    134045843 (PLCB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ccic04131]
    134045843 (PLCB2)
Enzymes [BR:ccic01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     134045843 (PLCB2)
Membrane trafficking [BR:ccic04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    134045843 (PLCB2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    134045843 (PLCB2)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 134045843
NCBI-ProteinID: XP_062351906
Position
6
AA seq 1211 aa
MSVLNPILKPTEVKEYLCKGDRFIKWDDETSNASPVILRVDPQGFYVYWTYQSTEREILD
ITNIRDTRAGRFAKMPKSLKLREVFNLDHPYSTFLLKTLTIVSGPDMVDLTFHNFVSYKE
NICKDWAEDIMAIARNPLMYNAPRYTFLEKILVKLKLQLNEEGKIPVRNIFQMFPADRKR
VEEALSACHLPNGKNDAINPEDFPEPVYKTFLMNLCPRPEIDEIFTSHHLKAKPYMTKEH
LAKFINKKQRDTRLNDILFPPAKPEQVQSLIEKYEPSGFNIQRGQLSPEGMVWFLCGPEN
NLIVLDKLMLYQDMTQPLSHYYINSSHNTYLTAGQFSGTSSPEMYRQTLLAGCRCVELDC
WKGRPPDEEPIITHGFTMTTEILFKDAIEAIAESAFKTSPYPVILSFENHVDSPKQQAKM
AEYCRTIFGDMLLTEPLEKYPLKPGVPLPSPKDLLRKILIKNKKNQSMSGKRQSSLKKGR
NMEPETTEQPTSVDADDTVWAGDVAEEEPEEEDEQLRNLDEEEIKKMQSDEGTAGLEVTA
YEEMSSLVNYIQPIKFNSFEVSAKKNRSYVISSFTEMKAGDLLSKFPMQFVEYNKWQMSR
IYPKGTRMDSSNYQPQMFWNVGCQMVALNFQTMDVPMQQNMALFEFNGQCGYLLKHEFMR
RPDKQFDPFSVDRIDGLVATTVCVTVLSGQFLSDRSVKTYVEVELLGLPRDAKRKHRTKL
TATANSINPVWKEEAFVFEKIMMPELASLKIVAWEEGGKFIGQRIIPIIAMHPGYHHVCL
RSESNMPLTMPALFVFLEIKDYVPDAWADLTIALSNPIKFFNLQDKRLMKLKDTSGERPG
TQTNLSPAETNGVAGSTGKPSIPPSNGSTGAAVFTKDEALLEVMQMAEPETITLAELQQK
KRFLKLLKRQEKELRELEQKGSKQREELLQKYSALFSEQAFPGGKKRTIRTRKTQKKRSV
TPSDAGISANPVKAAESIDHHWLVELRERLEMDLVHLGEEHHNRIRRKKEQHATEQVARI
LELAREKQAAELRVLRDTSESNIKDIKKRMEAKRVERVQAMLRNTSDKAAQERLKKEINN
SHIQEVVQTVKRVTEKTGRFQQKLEEKQAASLQSIKERESQLQQQVRVEYEEKLRALNME
VQEMVKNYTKASFPGEPQTGKEAGLSILEGERGSTDQLKANIPVAEVSRLTLAMTEPLGA
GMDVEIEESIF
NT seq 3636 nt   +upstreamnt  +downstreamnt
atgtctgtgctgaaccccatcctgaagcccacagaggtgaaggagtacctgtgcaagggc
gatcgcttcatcaaatgggatgatgaaacatcaaatgcttctcctgtgattctccgagtg
gatccccagggcttttatgtgtactggacctatcagagcacggaaagggaaattctggat
atcaccaacatccgagacacccgagcagggcgatttgccaaaatgcccaagtccctgaaa
ctccgagaggtttttaacttggatcacccttacagcaccttcctgctgaagaccctgaca
attgtatctggccctgacatggttgacctcactttccataactttgtgtcctacaaggag
aatatttgcaaggactgggctgaggatattatggccattgctcggaatcccctcatgtac
aacgctccccgctacaccttcctagagaaaattctagtgaagctgaagttgcaactgaat
gaagagggaaagattcctgtccggaatatttttcagatgttccctgcagacaggaagagg
gtggaagaagcattaagtgcttgtcatctgccaaatggcaagaatgatgccatcaacccc
gaggacttccccgagccggtgtacaagacgttccttatgaacctttgtccacggcctgag
attgatgagatatttacctcacaccatctaaaagcaaagccctacatgaccaaagagcac
ctggcaaagttcatcaacaagaagcagcgtgacacccgcctcaatgacatcctcttccca
ccagccaaacccgagcaggtgcagagcctgattgagaaatatgagcccagtgggtttaac
atccagagagggcagctgtctccagaggggatggtctggttcctgtgtggccctgagaac
aacctgatagtgctggacaagctgatgctgtaccaggacatgacacagccgctctcgcac
tactacatcaattcctcacacaacacctatctgacagctgggcagttttctgggacatcc
tctcccgaaatgtaccgccagacgctgctggccggctgccgctgcgtggagctggactgc
tggaagggccggcccccggacgaggagcccatcatcacccacggcttcaccatgacaact
gagatcctcttcaaggatgccattgaggccattgcagaaagtgcttttaaaacatctcca
tatcctgtgatcctgtccttcgagaaccatgtggactcgcccaagcagcaggcaaagatg
gccgagtactgccgaaccatttttggagatatgctgctgacagagccactagagaaatac
ccgctgaagccaggagttcctctgccaagtcctaaggatctcttaaggaaaatcttgatt
aaaaacaaaaagaaccaatctatgtctgggaagaggcagagctctttgaagaaggggagg
aacatggaaccagaaaccactgagcagccaacctctgtggatgctgacgatactgtctgg
gcaggtgatgtggctgaagaggagccagaggaagaggatgaacagctcagaaacctggat
gaagaggaaattaaaaagatgcagtcagatgagggcacggctggcctggaagtgacagcg
tacgaggagatgtccagcctggttaactacatacagcccatcaaattcaactccttcgag
gtctctgccaagaagaaccggagttacgtcatctcttccttcactgagatgaaggctggt
gatctactgagcaagttccccatgcagtttgtagaatacaataagtggcagatgagccgc
atttaccccaaaggcacccggatggactcctccaactaccagccccagatgttctggaat
gttggctgtcagatggtggcactcaacttccagaccatggatgtccccatgcagcagaac
atggccctgtttgagttcaacgggcagtgtgggtacctgctcaagcatgagttcatgcgg
cgccccgacaagcagttcgaccccttctctgtggaccgcatcgatgggctggtagccact
actgtctgtgtcacggtactctctggtcagttcctgtccgaccgcagcgtgaagacctac
gtggaagtggagctccttgggctgccaagggatgccaaacgcaagcacagaacgaaactg
accgccacggccaactccatcaacccggtgtggaaagaggaggcttttgtttttgaaaag
atcatgatgcccgagttggcatctctcaaaattgtggcttgggaagaaggagggaaattc
attggccagcgtatcattcccatcatcgcaatgcacccaggctaccaccacgtgtgcctg
cgcagtgagagcaacatgccgctcaccatgcccgccctcttcgtgttcctggagatcaag
gactatgtgccggatgcttgggcagatctcactattgccctctccaaccccatcaagttc
ttcaacctgcaggacaagcgcttgatgaagctcaaggatacctcaggagagaggcctggc
acacagacaaacctctcacctgctgagactaatggggtggcaggctccactgggaaaccc
agcattcctccctctaatgggtccacaggagcagcagtgttcaccaaggatgaagccctg
ttagaagtaatgcagatggcagaacctgaaacaatcacccttgctgagctgcagcagaag
aagcgcttcctgaagctgctgaagaggcaggagaaggagctgagggagctggagcagaag
ggaagcaaacagagggaggagctgctgcagaaatactctgcactcttttcagagcaggcc
ttccctgggggcaagaaaaggacaatacgcacaaggaaaacccagaagaagaggagtgtg
accccaagtgatgctggtatcagtgcaaatcctgtaaaagcagcagagagcatcgatcac
cactggctcgtggagctgagggagaggctggagatggacctcgtccaccttggggaggag
caccacaatcggatccgaaggaagaaagagcagcatgctaccgagcaagttgccaggatc
ctggagctggccagggagaagcaggcagctgagctgcgggtgctgagggacacatcagaa
agcaacattaaagacattaagaagaggatggaggcaaagagagtggagcgggtccaggcc
atgctgaggaataccagtgacaaggctgctcaggagaggttgaagaaagaaattaacaac
tcccacattcaggaggtggtacagacagtgaaacgggtgacagagaagactggcaggttc
cagcagaaactggaggagaagcaggcagcaagtctccagtccatcaaggagagagaaagc
cagctccagcagcaagtacgggtagaatatgaggagaagttgagagctctgaacatggag
gttcaggagatggtgaagaactacaccaaagccagctttcctggagagccacagactggg
aaggaagcaggtctgagcattcttgagggagaacgaggctctacagaccaactgaaagca
aatatcccagtggcagaggtgtccaggcttacactggcaatgactgagcccttgggagct
ggaatggatgtggagatagaagagagcatattctga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (7)   
   Pfam (7)   
All databases (14)   

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