KEGG   Crocuta crocuta (spotted hyena): 144226432
Entry
144226432         CDS       T11532                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
ccru  Crocuta crocuta (spotted hyena)
Pathway
ccru01522  Endocrine resistance
ccru04010  MAPK signaling pathway
ccru04015  Rap1 signaling pathway
ccru04068  FoxO signaling pathway
ccru04071  Sphingolipid signaling pathway
ccru04114  Oocyte meiosis
ccru04148  Efferocytosis
ccru04218  Cellular senescence
ccru04261  Adrenergic signaling in cardiomyocytes
ccru04370  VEGF signaling pathway
ccru04380  Osteoclast differentiation
ccru04517  IgSF CAM signaling
ccru04519  Cadherin signaling
ccru04550  Signaling pathways regulating pluripotency of stem cells
ccru04611  Platelet activation
ccru04613  Neutrophil extracellular trap formation
ccru04620  Toll-like receptor signaling pathway
ccru04621  NOD-like receptor signaling pathway
ccru04622  RIG-I-like receptor signaling pathway
ccru04625  C-type lectin receptor signaling pathway
ccru04657  IL-17 signaling pathway
ccru04658  Th1 and Th2 cell differentiation
ccru04659  Th17 cell differentiation
ccru04660  T cell receptor signaling pathway
ccru04664  Fc epsilon RI signaling pathway
ccru04668  TNF signaling pathway
ccru04670  Leukocyte transendothelial migration
ccru04714  Thermogenesis
ccru04722  Neurotrophin signaling pathway
ccru04723  Retrograde endocannabinoid signaling
ccru04728  Dopaminergic synapse
ccru04750  Inflammatory mediator regulation of TRP channels
ccru04912  GnRH signaling pathway
ccru04914  Progesterone-mediated oocyte maturation
ccru04917  Prolactin signaling pathway
ccru04926  Relaxin signaling pathway
ccru04932  Non-alcoholic fatty liver disease
ccru04933  AGE-RAGE signaling pathway in diabetic complications
ccru04935  Growth hormone synthesis, secretion and action
ccru04936  Alcoholic liver disease
ccru05014  Amyotrophic lateral sclerosis
ccru05020  Prion disease
ccru05022  Pathways of neurodegeneration - multiple diseases
ccru05132  Salmonella infection
ccru05133  Pertussis
ccru05135  Yersinia infection
ccru05140  Leishmaniasis
ccru05142  Chagas disease
ccru05145  Toxoplasmosis
ccru05152  Tuberculosis
ccru05161  Hepatitis B
ccru05163  Human cytomegalovirus infection
ccru05167  Kaposi sarcoma-associated herpesvirus infection
ccru05169  Epstein-Barr virus infection
ccru05170  Human immunodeficiency virus 1 infection
ccru05171  Coronavirus disease
ccru05205  Proteoglycans in cancer
ccru05208  Chemical carcinogenesis - reactive oxygen species
ccru05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ccru05415  Diabetic cardiomyopathy
ccru05417  Lipid and atherosclerosis
ccru05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccru00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    144226432 (MAPK11)
   04015 Rap1 signaling pathway
    144226432 (MAPK11)
   04370 VEGF signaling pathway
    144226432 (MAPK11)
   04668 TNF signaling pathway
    144226432 (MAPK11)
   04068 FoxO signaling pathway
    144226432 (MAPK11)
   04071 Sphingolipid signaling pathway
    144226432 (MAPK11)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    144226432 (MAPK11)
   04519 Cadherin signaling
    144226432 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    144226432 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    144226432 (MAPK11)
   04218 Cellular senescence
    144226432 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    144226432 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    144226432 (MAPK11)
   04613 Neutrophil extracellular trap formation
    144226432 (MAPK11)
   04620 Toll-like receptor signaling pathway
    144226432 (MAPK11)
   04621 NOD-like receptor signaling pathway
    144226432 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    144226432 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    144226432 (MAPK11)
   04660 T cell receptor signaling pathway
    144226432 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    144226432 (MAPK11)
   04659 Th17 cell differentiation
    144226432 (MAPK11)
   04657 IL-17 signaling pathway
    144226432 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    144226432 (MAPK11)
   04670 Leukocyte transendothelial migration
    144226432 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    144226432 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    144226432 (MAPK11)
   04917 Prolactin signaling pathway
    144226432 (MAPK11)
   04926 Relaxin signaling pathway
    144226432 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    144226432 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    144226432 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    144226432 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    144226432 (MAPK11)
   04722 Neurotrophin signaling pathway
    144226432 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    144226432 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    144226432 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    144226432 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    144226432 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    144226432 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    144226432 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    144226432 (MAPK11)
   05161 Hepatitis B
    144226432 (MAPK11)
   05171 Coronavirus disease
    144226432 (MAPK11)
   05163 Human cytomegalovirus infection
    144226432 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    144226432 (MAPK11)
   05169 Epstein-Barr virus infection
    144226432 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    144226432 (MAPK11)
   05135 Yersinia infection
    144226432 (MAPK11)
   05133 Pertussis
    144226432 (MAPK11)
   05152 Tuberculosis
    144226432 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    144226432 (MAPK11)
   05140 Leishmaniasis
    144226432 (MAPK11)
   05142 Chagas disease
    144226432 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    144226432 (MAPK11)
   05020 Prion disease
    144226432 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    144226432 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    144226432 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    144226432 (MAPK11)
   05415 Diabetic cardiomyopathy
    144226432 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    144226432 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    144226432 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    144226432 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    144226432 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ccru01001]
    144226432 (MAPK11)
Enzymes [BR:ccru01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     144226432 (MAPK11)
Protein kinases [BR:ccru01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   144226432 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH RIO1 Cas_CT1975
Other DBs
NCBI-GeneID: 144226432
NCBI-ProteinID: XP_077613960
Position
Unknown
AA seq 372 aa
MPRTLGSSEQTCSRGACPWGQNRLKRSRAWGHTAGPPLHRLTHPPCSSAYDTRLRQKVAV
KKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGAD
LNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLA
RQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQL
KRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLRSIFHGANPLAVDLLGRMLVLD
SDQRVSAAEALAHAYFSQYHDPDDEPEAEPYDESVEAKERTVEEWKELTYQEVLSFKPPE
PPQSPGSLEIEQ
NT seq 1119 nt   +upstreamnt  +downstreamnt
atgccgcgcaccctagggtcctccgagcaaacgtgcagcagaggtgcgtgcccatggggc
cagaataggctcaaaaggagcagggcctgggggcacacggctggtccccctctgcaccgc
ctcactcacccaccttgcagctcagcctatgacacgcggctgcgccagaaggtggcggtg
aagaagttgtcgcgacccttccagtcgctgattcacgcgcggagaacttaccgggagctg
cggctgctcaaacacctgaagcatgagaacgtcatcgggctgctggacgtgttcacgcca
gctacctccattgaggacttcagcgaagtgtacctggtgaccaccctgatgggcgccgac
ctgaacaacatcgtcaagtgccaggcgctgagcgacgagcacgtccagttcctggtttac
cagctcctgcgcgggctcaagtacatccactccgcggggatcatccaccgggacctgaag
cccagcaacgtggccgtcaacgaggactgcgagcttcggatcctggattttgggctagcc
cgtcaggccgatgaggagatgaccggctacgtggccacccgctggtaccgtgcccctgag
atcatgctcaactggatgcactacaaccagacagtggacatctggtctgtgggctgcatc
atggctgagctgctccagggaaaggccctcttcccaggaaatgactacatcgaccagctg
aagcgaatcatggaggtggtgggcacgcccagccctgaggtcctagcgaagatatcctca
gaacacgcccggacgtacatccagtccctgccccccatgccccagaaggacctcaggagc
atcttccatggagccaaccctctggctgtggacctcctgggaaggatgctggtgctggac
agcgaccagagggtcagcgcggccgaggccctggcccacgcctacttcagccagtaccat
gaccccgacgatgagcccgaggctgagccctacgatgagagcgtggaggccaaggagcgc
acagtggaggagtggaaggagctcacctaccaggaggtcctcagcttcaagcccccggag
ccaccacagtcacctggcagcctggagattgagcagtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (11)   

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