KEGG   Camelus dromedarius (Arabian camel): 105101292
Entry
105101292         CDS       T04642                                 
Symbol
PLCB1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
cdk  Camelus dromedarius (Arabian camel)
Pathway
cdk00562  Inositol phosphate metabolism
cdk01100  Metabolic pathways
cdk04015  Rap1 signaling pathway
cdk04020  Calcium signaling pathway
cdk04022  cGMP-PKG signaling pathway
cdk04062  Chemokine signaling pathway
cdk04070  Phosphatidylinositol signaling system
cdk04071  Sphingolipid signaling pathway
cdk04072  Phospholipase D signaling pathway
cdk04081  Hormone signaling
cdk04082  Neuroactive ligand signaling
cdk04261  Adrenergic signaling in cardiomyocytes
cdk04270  Vascular smooth muscle contraction
cdk04310  Wnt signaling pathway
cdk04371  Apelin signaling pathway
cdk04540  Gap junction
cdk04611  Platelet activation
cdk04613  Neutrophil extracellular trap formation
cdk04621  NOD-like receptor signaling pathway
cdk04713  Circadian entrainment
cdk04720  Long-term potentiation
cdk04723  Retrograde endocannabinoid signaling
cdk04724  Glutamatergic synapse
cdk04725  Cholinergic synapse
cdk04726  Serotonergic synapse
cdk04728  Dopaminergic synapse
cdk04730  Long-term depression
cdk04742  Taste transduction
cdk04750  Inflammatory mediator regulation of TRP channels
cdk04911  Insulin secretion
cdk04912  GnRH signaling pathway
cdk04915  Estrogen signaling pathway
cdk04916  Melanogenesis
cdk04918  Thyroid hormone synthesis
cdk04919  Thyroid hormone signaling pathway
cdk04921  Oxytocin signaling pathway
cdk04922  Glucagon signaling pathway
cdk04924  Renin secretion
cdk04925  Aldosterone synthesis and secretion
cdk04926  Relaxin signaling pathway
cdk04927  Cortisol synthesis and secretion
cdk04928  Parathyroid hormone synthesis, secretion and action
cdk04929  GnRH secretion
cdk04933  AGE-RAGE signaling pathway in diabetic complications
cdk04934  Cushing syndrome
cdk04935  Growth hormone synthesis, secretion and action
cdk04961  Endocrine and other factor-regulated calcium reabsorption
cdk04970  Salivary secretion
cdk04971  Gastric acid secretion
cdk04972  Pancreatic secretion
cdk04973  Carbohydrate digestion and absorption
cdk05010  Alzheimer disease
cdk05016  Huntington disease
cdk05017  Spinocerebellar ataxia
cdk05022  Pathways of neurodegeneration - multiple diseases
cdk05142  Chagas disease
cdk05143  African trypanosomiasis
cdk05146  Amoebiasis
cdk05163  Human cytomegalovirus infection
cdk05200  Pathways in cancer
cdk05415  Diabetic cardiomyopathy
cdk05417  Lipid and atherosclerosis
Module
cdk_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:cdk00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    105101292 (PLCB1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    105101292 (PLCB1)
   04310 Wnt signaling pathway
    105101292 (PLCB1)
   04371 Apelin signaling pathway
    105101292 (PLCB1)
   04020 Calcium signaling pathway
    105101292 (PLCB1)
   04070 Phosphatidylinositol signaling system
    105101292 (PLCB1)
   04072 Phospholipase D signaling pathway
    105101292 (PLCB1)
   04071 Sphingolipid signaling pathway
    105101292 (PLCB1)
   04022 cGMP-PKG signaling pathway
    105101292 (PLCB1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    105101292 (PLCB1)
   04081 Hormone signaling
    105101292 (PLCB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    105101292 (PLCB1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105101292 (PLCB1)
   04613 Neutrophil extracellular trap formation
    105101292 (PLCB1)
   04621 NOD-like receptor signaling pathway
    105101292 (PLCB1)
   04062 Chemokine signaling pathway
    105101292 (PLCB1)
  09152 Endocrine system
   04911 Insulin secretion
    105101292 (PLCB1)
   04922 Glucagon signaling pathway
    105101292 (PLCB1)
   04929 GnRH secretion
    105101292 (PLCB1)
   04912 GnRH signaling pathway
    105101292 (PLCB1)
   04915 Estrogen signaling pathway
    105101292 (PLCB1)
   04921 Oxytocin signaling pathway
    105101292 (PLCB1)
   04926 Relaxin signaling pathway
    105101292 (PLCB1)
   04935 Growth hormone synthesis, secretion and action
    105101292 (PLCB1)
   04918 Thyroid hormone synthesis
    105101292 (PLCB1)
   04919 Thyroid hormone signaling pathway
    105101292 (PLCB1)
   04928 Parathyroid hormone synthesis, secretion and action
    105101292 (PLCB1)
   04916 Melanogenesis
    105101292 (PLCB1)
   04924 Renin secretion
    105101292 (PLCB1)
   04925 Aldosterone synthesis and secretion
    105101292 (PLCB1)
   04927 Cortisol synthesis and secretion
    105101292 (PLCB1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105101292 (PLCB1)
   04270 Vascular smooth muscle contraction
    105101292 (PLCB1)
  09154 Digestive system
   04970 Salivary secretion
    105101292 (PLCB1)
   04971 Gastric acid secretion
    105101292 (PLCB1)
   04972 Pancreatic secretion
    105101292 (PLCB1)
   04973 Carbohydrate digestion and absorption
    105101292 (PLCB1)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    105101292 (PLCB1)
  09156 Nervous system
   04724 Glutamatergic synapse
    105101292 (PLCB1)
   04725 Cholinergic synapse
    105101292 (PLCB1)
   04728 Dopaminergic synapse
    105101292 (PLCB1)
   04726 Serotonergic synapse
    105101292 (PLCB1)
   04720 Long-term potentiation
    105101292 (PLCB1)
   04730 Long-term depression
    105101292 (PLCB1)
   04723 Retrograde endocannabinoid signaling
    105101292 (PLCB1)
  09157 Sensory system
   04742 Taste transduction
    105101292 (PLCB1)
   04750 Inflammatory mediator regulation of TRP channels
    105101292 (PLCB1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    105101292 (PLCB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105101292 (PLCB1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    105101292 (PLCB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    105101292 (PLCB1)
   05142 Chagas disease
    105101292 (PLCB1)
   05143 African trypanosomiasis
    105101292 (PLCB1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105101292 (PLCB1)
   05016 Huntington disease
    105101292 (PLCB1)
   05017 Spinocerebellar ataxia
    105101292 (PLCB1)
   05022 Pathways of neurodegeneration - multiple diseases
    105101292 (PLCB1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105101292 (PLCB1)
   05415 Diabetic cardiomyopathy
    105101292 (PLCB1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    105101292 (PLCB1)
   04934 Cushing syndrome
    105101292 (PLCB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cdk04131]
    105101292 (PLCB1)
Enzymes [BR:cdk01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     105101292 (PLCB1)
Membrane trafficking [BR:cdk04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    105101292 (PLCB1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    105101292 (PLCB1)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like
Other DBs
NCBI-GeneID: 105101292
NCBI-ProteinID: XP_031290091
Position
19
AA seq 1215 aa
MAGPARSARSATQARVRVHSLKKGTKFVKWDDDSTLVTPIILRTDPHGFFFYWTDQNKET
ELLDLSLVKDARCGKHAKAPKDPKLRELLDVGNIGRLEHRMITVVYGPDLVNISHLNLVA
FQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSAD
RKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLT
VDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSG
EENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVE
LDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQ
AKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKK
LSEQASNTCSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMS
NLVNYIQPVKFESFEISKKRNRSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKG
TRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKH
FDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGN
AVNPVWEEEPIVFKKVVLPSLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERN
QPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKE
ADPGETPSEAPSEARTTPAENGVNHTASLTPRPPSQALHSQPTPGSVKAPAKTEDLIQSV
LTEVEAQTVEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLR
RRAALEKTARKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDRQQQQLLNLRQ
EQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKIT
EAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPK
LQVQLEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHSSAPAPLASDPGKLNHKPPSGE
ELEGENPGKEFDTPL
NT seq 3648 nt   +upstreamnt  +downstreamnt
atggccgggccagcccggagtgcacgctctgcaactcaagcccgtgtgcgtgtccacagc
ctcaagaagggcaccaaattcgtcaagtgggatgatgactccactcttgttactccaatt
attttgaggactgaccctcacggatttttcttttactggacagatcaaaacaaggagacg
gagctgttagacctcagccttgtcaaagatgccagatgtgggaaacacgccaaggctccc
aaggaccccaagttacgggaacttttggatgtggggaacatcgggcgcctggaacatcgc
atgataaccgtggtgtacggacctgacttagttaacatctcccatttgaatctcgtggct
ttccaagaagaggtggccaaggaatggacaaatgaggttttcagtttggcaacaaacctg
ctggcccagaacatgtccagggacgcatttctggaaaaagcctatactaaactgaagctg
caagtcactccggaaggacgcattcctctcaaaaacatataccgcttgttctcagcagac
cggaagcgagtcgaaactgcattagaggcttgtagtcttccatcttcaaggaatgattcg
atacctcaagaagatttcactccagaagtgtacagagttttcctgaacaacctgtgtcct
cgacctgaaattgataacatcttttccgaatttggtgccaaaagcaaaccataccttacg
gttgatcagatgatggattttatcaaccttaagcagcgagatccccggctaaatgagata
ctttacccacctttaaagcaagagcaagtccaagtgttgattgagaagtatgaacccaat
aacagcctcgccagaaaaggacagatatcagtggacggatttatgcgctacctgagtggg
gaagaaaacggagtcgtttcacctgagaaactggacttgaatgaagatatgtctcagccc
ctttctcactatttcattaactcctcacacaacacctacctcacagctggccagctggct
ggaaactcctccgtcgagatgtatcgtcaagtgctcctgtctggttgtcgctgtgtagag
ttggactgctggaagggacggactgcagaagaggagccagtcatcacgcatgggttcacc
atgaccacagaaatatccttcaaggaagtaatagaagcgattgcagagtgtgcatttaag
acgtcacccttcccaattctgctttcatttgagaaccatgtggattccccaaagcagcag
gccaagatggcggagtattgccgactgatcttcggggatgcccttctcatggaaccactg
gaaaagtacccactggaatctggagttcctcttccaagccctatggatttaatgtacaaa
atcttagtgaaaaataagaagaaatcacacaagtcatcggaaggaagtggcaaaaagaag
ctctcggaacaagcctccaacacgtgcagcgactcctccagcgtgttcgagccctcgtcc
ccgggagccggagaagcagatacggagagtgatgacgacgatgatgatgatgactgtaaa
aagtcttcgatggatgaggggactgctgggagcgaagccatggccacggaagagatgtct
aatctggtgaactatattcagcccgtcaagtttgaatcatttgaaatttcaaaaaaaagg
aatagaagttttgaaatgtcttccttcgtggaaactaaaggacttgaacaactcaccaag
tctccagtggaatttgtagaatataacaaaatgcagctaagcaggatatatccaaaagga
acccgcgtggattcctccaactacatgcctcagctcttctggaacgcaggctgccaaatg
gttgcacttaatttccaaaccgtagacctggcaatgcaaatcaacatgggcatgtatgaa
tacaacggcaagagtggctacagactgaagccggagttcatgaggcggcctgacaagcat
tttgatcctttcaccgaaggcatcgtggatgggatagtggccaacaccttgtctgtgaag
attatttcaggtcaatttctttctgataagaaagtcgggacttatgtggaagtggatatg
tttggtttgcctgtggacacaaggaggaaggcatttaagaccaagacatcacaaggaaat
gccgtaaatcctgtctgggaggaagaacccattgttttcaaaaaggtagttcttccttcc
ctggcctgtttgaggatagcagtttatgaagaaggaggtaaatttattggtcaccggatc
ttgccagtacaagcaattcgaccaggctatcactacatctgcctgagaaatgagaggaac
cagcctctgacgctcccagctgtctttgtctacatagaggtgaaggactatgtcccagat
acatatgcagacgtgattgaggctttgtcaaatccaatccgatatgtgaatctgatggaa
cagagagctaagcaactggctgctttgacattggaagatgaagaagaagtaaagaaagag
gccgatcctggggaaacaccatcagaagctccgagtgaagccaggacaactccggcagaa
aatggggtgaatcacactgcatccctgacacccagaccaccctcccaggctctccacagc
caaccaactccaggttctgtaaaggcacctgctaaaacggaagatctcattcagagtgtt
ttaacagaagtggaggcgcagacagttgaagagctgaagcaacaaaagtcgtttgtgaaa
cttcagaagaagcactacaaagaaatgaaagacctggttaagagacaccacaagaaaacc
actgacctcatcaaagaacacactacaaaatacaacgaaatccagaatgactatctgaga
aggagagcagctttggaaaagacagccagaaaggacagtaagaaaaaatcggaacccagc
agccctgaccacgggtcgtcgacgattgagcaggacctcgctgccctggacgccgaaatg
acccaaaagttaatagacctgaaggacaggcagcagcagcagctgctgaatcttcggcaa
gaacagtattacagtgaaaagtaccagaagcgagaacatattaagctgcttattcaaaaa
ttgacggatgttgctgaagaatgtcagaataatcagttaaagaagctcaaggaaatctgt
gagaaagagaagaaggaattaaagaagaaaatggataaaaagagacaggagaagataaca
gaagctaaatccaaagacaaaagccagatggaggaggaaaagacagagatgatccggtca
tacattcaggaggtggtgcagtacatcaagaggttagaagaggcacaaagtaaacggcaa
gaaaaactcgtagagaaacacaaagagatccggcagcagatcctggacgaaaagcccaag
ctgcaggtgcagctggagcaagagtaccaagacaagttcaaaaggctgcccctggagatt
ctggagttcgtgcaggaagccatgaaagggaagatcagtgaagacagcaatcacagttct
gcccctgcccctctggcctcagaccctggaaaactgaaccacaagcctccttccggggag
gagctggaaggagaaaacccaggaaaagagtttgacactcctctgtga

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (7)   
   RefSeq(pep) (7)   
DNA sequence (11)   
   RefSeq(nuc) (7)   
   GenBank (2)   
   EMBL (2)   
Protein domain (6)   
   Pfam (6)   
All databases (27)   

Download RDF
DBGET integrated database retrieval system