KEGG   Capra hircus (goat): 102180926
Entry
102180926         CDS       T02910                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
chx  Capra hircus (goat)
Pathway
chx01522  Endocrine resistance
chx04010  MAPK signaling pathway
chx04015  Rap1 signaling pathway
chx04068  FoxO signaling pathway
chx04071  Sphingolipid signaling pathway
chx04114  Oocyte meiosis
chx04148  Efferocytosis
chx04218  Cellular senescence
chx04261  Adrenergic signaling in cardiomyocytes
chx04370  VEGF signaling pathway
chx04380  Osteoclast differentiation
chx04517  IgSF CAM signaling
chx04519  Cadherin signaling
chx04550  Signaling pathways regulating pluripotency of stem cells
chx04611  Platelet activation
chx04613  Neutrophil extracellular trap formation
chx04620  Toll-like receptor signaling pathway
chx04621  NOD-like receptor signaling pathway
chx04622  RIG-I-like receptor signaling pathway
chx04625  C-type lectin receptor signaling pathway
chx04657  IL-17 signaling pathway
chx04658  Th1 and Th2 cell differentiation
chx04659  Th17 cell differentiation
chx04660  T cell receptor signaling pathway
chx04664  Fc epsilon RI signaling pathway
chx04668  TNF signaling pathway
chx04670  Leukocyte transendothelial migration
chx04714  Thermogenesis
chx04722  Neurotrophin signaling pathway
chx04723  Retrograde endocannabinoid signaling
chx04728  Dopaminergic synapse
chx04750  Inflammatory mediator regulation of TRP channels
chx04912  GnRH signaling pathway
chx04914  Progesterone-mediated oocyte maturation
chx04917  Prolactin signaling pathway
chx04926  Relaxin signaling pathway
chx04932  Non-alcoholic fatty liver disease
chx04933  AGE-RAGE signaling pathway in diabetic complications
chx04935  Growth hormone synthesis, secretion and action
chx04936  Alcoholic liver disease
chx05014  Amyotrophic lateral sclerosis
chx05020  Prion disease
chx05022  Pathways of neurodegeneration - multiple diseases
chx05132  Salmonella infection
chx05133  Pertussis
chx05135  Yersinia infection
chx05140  Leishmaniasis
chx05142  Chagas disease
chx05145  Toxoplasmosis
chx05152  Tuberculosis
chx05161  Hepatitis B
chx05163  Human cytomegalovirus infection
chx05167  Kaposi sarcoma-associated herpesvirus infection
chx05169  Epstein-Barr virus infection
chx05170  Human immunodeficiency virus 1 infection
chx05171  Coronavirus disease
chx05205  Proteoglycans in cancer
chx05208  Chemical carcinogenesis - reactive oxygen species
chx05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
chx05415  Diabetic cardiomyopathy
chx05417  Lipid and atherosclerosis
chx05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:chx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102180926 (MAPK12)
   04015 Rap1 signaling pathway
    102180926 (MAPK12)
   04370 VEGF signaling pathway
    102180926 (MAPK12)
   04668 TNF signaling pathway
    102180926 (MAPK12)
   04068 FoxO signaling pathway
    102180926 (MAPK12)
   04071 Sphingolipid signaling pathway
    102180926 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    102180926 (MAPK12)
   04519 Cadherin signaling
    102180926 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102180926 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    102180926 (MAPK12)
   04218 Cellular senescence
    102180926 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    102180926 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102180926 (MAPK12)
   04613 Neutrophil extracellular trap formation
    102180926 (MAPK12)
   04620 Toll-like receptor signaling pathway
    102180926 (MAPK12)
   04621 NOD-like receptor signaling pathway
    102180926 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    102180926 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    102180926 (MAPK12)
   04660 T cell receptor signaling pathway
    102180926 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    102180926 (MAPK12)
   04659 Th17 cell differentiation
    102180926 (MAPK12)
   04657 IL-17 signaling pathway
    102180926 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    102180926 (MAPK12)
   04670 Leukocyte transendothelial migration
    102180926 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102180926 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    102180926 (MAPK12)
   04917 Prolactin signaling pathway
    102180926 (MAPK12)
   04926 Relaxin signaling pathway
    102180926 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    102180926 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102180926 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    102180926 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    102180926 (MAPK12)
   04722 Neurotrophin signaling pathway
    102180926 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102180926 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102180926 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    102180926 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102180926 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    102180926 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102180926 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102180926 (MAPK12)
   05161 Hepatitis B
    102180926 (MAPK12)
   05171 Coronavirus disease
    102180926 (MAPK12)
   05163 Human cytomegalovirus infection
    102180926 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102180926 (MAPK12)
   05169 Epstein-Barr virus infection
    102180926 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102180926 (MAPK12)
   05135 Yersinia infection
    102180926 (MAPK12)
   05133 Pertussis
    102180926 (MAPK12)
   05152 Tuberculosis
    102180926 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102180926 (MAPK12)
   05140 Leishmaniasis
    102180926 (MAPK12)
   05142 Chagas disease
    102180926 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102180926 (MAPK12)
   05020 Prion disease
    102180926 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    102180926 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102180926 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    102180926 (MAPK12)
   05415 Diabetic cardiomyopathy
    102180926 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102180926 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    102180926 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102180926 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102180926 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:chx01001]
    102180926 (MAPK12)
Enzymes [BR:chx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     102180926 (MAPK12)
Protein kinases [BR:chx01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   102180926 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kinase-like
Other DBs
NCBI-GeneID: 102180926
NCBI-ProteinID: XP_017904445
Position
5:complement(118578270..118586626)
AA seq 376 aa
MGSSLPSLAEVKDAYRLAWLPGGVLGVSPGLPILSSLPPVQRHHSAFFRPPPLPQTSVSL
VTLRKRQNTVLTCLVSRGPRGGARGSAVGGGDCVSQGDGAPCGPERLCPIVRCSYLVMPF
MGTDLGKLMKHEKLSEDRVQFLVYQTLKGLKYIHAAGVIHRDLKPSNLAVNEDCELKILD
FGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGNDH
LDQLKEIMKVTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASVLTNASPLAVSLLEKM
LVLDAEQRVTAAEALAHPYFESLHDTEDEPQAQKYDESFDDVDRTLDEWKRVTYKEVLSF
KPPRQLGAKASKETAL
NT seq 1131 nt   +upstreamnt  +downstreamnt
atgggctcctcgctgcccagcctcgcggaggtcaaggacgcatacagactggcctggctt
cctggtggggtgcttggggtgtctcccggtctccccatcctgtccagcttgccccctgtc
cagaggcaccactctgctttttttcgcccccctcccctgcctcaaacctcggtctccctg
gttacccttcggaaacgccaaaacacagtcctcacctgcctggtgtcgcggggcccgcgg
ggtggggcccggggcagcgccgtgggaggcggggactgcgtgtcgcagggtgacggggcc
ccgtgcggccctgagcgtctctgccccatcgtgcgctgcagctacctggtgatgccgttc
atgggcaccgacctgggaaagctcatgaagcacgagaagctgagcgaagaccgggtgcag
ttcctcgtctaccagacgctcaaggggctgaagtacatccacgctgccggcgtcatccat
agggacctgaagcccagcaacctggctgtgaacgaggactgtgagctgaagatcctggac
ttcggcctggcccggcaggcagacagcgagatgaccggctacgtggtgacccggtggtac
cgcgcgcccgaggtcatcctgaactggatgcgctacacgcagacggtggacatctggtcc
gtgggctgcatcatggctgagatgatcacagggaagacgctcttcaaaggcaacgaccac
ctggaccagctgaaggagatcatgaaggtgacagggacgcctcccgcggagtttgtgcag
aggctgcaaagtgacgaggccaagaactacatgaaaggcctccctgagctggagaagaag
gattttgcctccgtcctgaccaacgcaagccccctggccgtgagcctcctggagaaaatg
ctggtgctggatgcagagcagcgggtgacggcggccgaggcgctggcccatccctacttc
gagtcactgcacgacacggaggacgagccccaggcccagaagtacgatgagtcctttgac
gacgtggaccgcacgctggacgagtggaagcgtgtcacatataaagaggtgctcagcttc
aagcctccccggcagctgggggccaaggcctccaaggagacagccttgtga

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (9)   
   RefSeq(nuc) (3)   
   GenBank (3)   
   EMBL (3)   
Protein domain (5)   
   Pfam (5)   
All databases (20)   

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