KEGG   Carettochelys insculpta (pitted-shelled turtle): 142019335
Entry
142019335         CDS       T11194                                 
Symbol
PLCB3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ciz  Carettochelys insculpta (pitted-shelled turtle)
Pathway
ciz00562  Inositol phosphate metabolism
ciz01100  Metabolic pathways
ciz04020  Calcium signaling pathway
ciz04070  Phosphatidylinositol signaling system
ciz04081  Hormone signaling
ciz04082  Neuroactive ligand signaling
ciz04261  Adrenergic signaling in cardiomyocytes
ciz04270  Vascular smooth muscle contraction
ciz04310  Wnt signaling pathway
ciz04371  Apelin signaling pathway
ciz04540  Gap junction
ciz04621  NOD-like receptor signaling pathway
ciz04912  GnRH signaling pathway
ciz04916  Melanogenesis
Module
ciz_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ciz00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    142019335 (PLCB3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    142019335 (PLCB3)
   04371 Apelin signaling pathway
    142019335 (PLCB3)
   04020 Calcium signaling pathway
    142019335 (PLCB3)
   04070 Phosphatidylinositol signaling system
    142019335 (PLCB3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    142019335 (PLCB3)
   04081 Hormone signaling
    142019335 (PLCB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    142019335 (PLCB3)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    142019335 (PLCB3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    142019335 (PLCB3)
   04916 Melanogenesis
    142019335 (PLCB3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    142019335 (PLCB3)
   04270 Vascular smooth muscle contraction
    142019335 (PLCB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ciz04131]
    142019335 (PLCB3)
Enzymes [BR:ciz01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     142019335 (PLCB3)
Membrane trafficking [BR:ciz04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    142019335 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    142019335 (PLCB3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PI-PLC-Y PH_14 PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 142019335
NCBI-ProteinID: XP_074862161
Position
11
AA seq 1258 aa
MGDFNHPDSWETNTATHRQSRKFLESVGDNFLMYMLKEPTRGCTQLDLLLPNREELVGEI
DVSGNLGCSDHEMVDFRILTKGRKEPTTQTMVTLRVDPLGFFLYWNAPQMEVELLDISSI
RDTRTGRYARVPKEPKLREILGLGGSEPHPEEKLLTVVHGPDLVNISFLNFMAVQEDVAK
IWTEELFKLAMNILAQNASRNTFLQKIYTRLKLQVNQESRIPVKNILKMFSADKKRVETA
LESCGLNFNRSESIKPDEFTLEIFERFLNKLCLRPDIDKILLEIGAKGKPYLSLDQLMDF
INQRQRDPRLNEVLYPPLSHDQVRQLIDKYEPNRQFLERDQMSMEGFGRYLGGEENSIVP
PEKLDLSDDMSQPLSSYFINSSHNTYLTAGQLTGNSSVEMYRQVLLSGCRCIELDCWKGR
PQDEEPFITHGFTMTTEIPFKEVIEAIAESAFKTSPFPVILSFENHVDSAKQQAKMAEYC
RSIFGEALLIEPLEKYPLQAGVALPSPQELMGRILVKNKKQRQRRASKGPEGTSIRKRLL
EPTVSDVGSGLGDLPSPPPGFPCVEQHKGATPQVIVNGEEKVLPERLAKLAEPRKSIDRE
AESEEEEEEEQPDPKKPTTDEGTASSEVNATEEMSTLVNYIEPVKFKSFQAASKRNKSFE
MSSFVETKGLEQLTKSPMEFVEYNKKQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNF
QSLDLPMQLNLGMFEYNRRSGYLLKPEFMRREDKLFDPFTENIVDGIVANTVKVKIISGQ
FLSDKRVGIYVEVDTFGLPVDTKRKFRTRPSQGNSLNPVWDEEPFVFPKVVLPTLASLRI
AVFEEGGKFVGHRILPVSAIRSGYHYICLRSESNQPLSLPALLVYTEANDYIPDDHQDYA
EALINPIKHVSLMDQRAKQLVALMEESEESAEKPRETPGKQRPDVVAEPPTDSRQPPTAL
LSPTPSVASPGQRDDLIASVLAEVLPQSLEELRQQKGYIKLLKKQYRELKELRKKHMKNI
SSLNKKLSTQVNQLHSNPLRRRSRVEWSLRRGQQDANGSLEALEQEVSRQKVELQEGQLR
GLLQLRENQHQVERARKIEHLRQAQQRLRDITLDCQAAQLKRIKEMSEREKKELQKILDR
KRHNSITEAKSRERQKKDVELTEINRRHINESVNSIRRLEEAQKRRQEKLVTGHQDILQQ
IEEEEPRLVEKLEQECELEAQVLPQEIRRFLQAELEGGVSNGHPPAAPQEEEDENTVL
NT seq 3777 nt   +upstreamnt  +downstreamnt
atgggagactttaatcatccggacagttgggagaccaatacagccacacacagacaatcc
aggaagtttttggagagtgttggagataacttcttgatgtacatgctgaaggagccaacc
aggggctgtacacaacttgacctgctgctcccaaacagggaagaacttgtaggcgaaata
gacgtgagtggcaacctgggctgcagtgaccatgagatggtagatttcaggattctgaca
aaaggaagaaaggagccaacaacccagaccatggtgacgctgcgggtggaccccttggga
ttcttcctctactggaatgcaccccaaatggaagttgaactcctggacatcagctccatc
cgagacacgaggactgggcgctatgccagagtcccgaaggagcccaagttgcgggagata
ttggggttggggggctcagagcctcaccctgaggagaagctgctgactgtggtgcatggc
cccgacctggtcaacatcagcttcctgaacttcatggccgtgcaggaggacgtggccaag
atctggactgaggagctgttcaaactggctatgaacattctagcccaaaatgcgtctcgc
aacaccttcctgcagaaaatatacacccgacttaaactccaggtgaaccaggagagccgg
atcccagtgaaaaacatcttgaagatgttctcggcagataagaagcgtgtggagacagct
ctggagtcctgtggccttaacttcaatcgaagtgagtccatcaaacctgacgaattcacc
ctggagatctttgagcgcttcctaaacaagctctgcctacgtcccgacatcgataaaatc
ctgctggagattggggcgaaggggaagccctacctgagcctggaccagctgatggatttc
atcaaccagcggcagcgggacccgcggctgaacgaggtgctgtacccgcctctcagccac
gaccaggtgcgccagctcatcgacaaatacgagcccaaccgccagttcctggagcgtgac
cagatgtcgatggaggggttcgggcgctacctggggggggaggagaacagcatcgtcccc
cctgaaaagctggacctgagcgacgacatgagccagccactgagcagctacttcatcaac
tcctcccacaacacctacctcacagccggccagctgacagggaactcctccgtggagatg
tatcggcaggtgctgctgagtggctgccgctgcatcgaacttgactgctggaaggggcgg
ccccaggacgaggagcccttcatcactcatggcttcaccatgacaactgagatccccttc
aaggaggtgatcgaggccattgctgaaagcgctttcaagacctccccgttccccgtcatc
ctgtccttcgagaaccacgttgactcggccaagcagcaggccaagatggctgagtactgc
cgcagcatcttcggggaggctctgctcatcgagcccctggagaaatacccgctgcaagcg
ggcgtggcgctccccagcccccaggagctgatgggccgcatcctggtgaagaacaagaag
cagcggcagcgacgggcaagcaagggccccgaggggaccagtatccgcaagcgcctgctg
gagcctacagtgagcgatgtggggtcgggcctcggggatctgccctcacccccgccaggc
tttccctgtgtcgagcagcacaaaggggccacccctcaggtcattgtcaatggggaggag
aaggtgctgccggagagactggccaagctggctgagccccgcaaatctatcgaccgggag
gctgagagtgaggaggaggaggaggaagagcagccagaccccaagaaacccaccacagat
gagggcactgccagcagtgaggtgaatgctactgaggagatgtccacactggtgaattac
atcgaacccgtcaaattcaaatccttccaggcggccagcaagcggaacaagtccttcgag
atgtcgtccttcgtggagaccaaggggctggagcagctcaccaagagccccatggagttc
gtggaatacaacaagaagcagctcagccgcatctaccccaagggcacacgggtcgactcc
tccaactacatgccccagctcttctggaacgccggctgccagatggtggcgctcaacttc
cagtccctcgacctgcccatgcagctgaatctgggcatgtttgagtacaaccggcgcagc
gggtacctgctgaagcccgagttcatgcggcgcgaggacaagctcttcgatcccttcacg
gagaacatcgtggacggcatcgtggccaatacggtcaaggtcaagatcatctcggggcag
ttcctgtcagacaagcgggtgggcatctacgtggaagtggacacgttcggcctccccgtg
gacaccaagcgcaagttccggacgcgcccgtcccaggggaactccctcaaccccgtgtgg
gacgaggagcccttcgtcttccccaaggtggtgctgcccacgctggcctccctgcgcatc
gctgtctttgaggaggggggcaaattcgtcgggcaccggatcctgcctgtctcagccatc
cgctctggataccactacatctgcctgcgcagtgaaagcaaccagcccctcagcctgccc
gccctgctggtctacacggaagccaacgactacatcccggacgaccaccaagactacgca
gaggccctgatcaaccccatcaaacacgtcagcctcatggaccagcgggccaaacagctg
gtggcgctgatggaagaaagcgaggagagtgcagagaagccgcgggaaacacctgggaag
cagcgacctgatgtggtggccgagccccccacagattcccgacagccgcccactgccctg
ctgtcccctacccccagtgtcgccagcccagggcaaagggatgacctcattgccagtgtc
ctcgcagaggtgctcccccagtccctggaggagctgcggcagcaaaagggctacatcaaa
ctgctgaagaaacagtaccgagagctgaaggagctacgcaagaagcacatgaagaacatt
tccagcctcaacaagaagctgagcactcaagtcaaccagctgcacagcaaccccctccgg
cgccgctcccgggtggaatggagcctgcgccgtggacagcaggatgccaacggctccctg
gaggccctggagcaggaggtgtctcggcagaaggtggaactgcaggaggggcagctgcgg
ggtctgctacagctgcgggaaaaccagcaccaggtggagcgagcccgcaaaatcgagcac
ctgcgccaggcccagcagcggctgcgggacattactctggattgccaggctgcccagctg
aagcgaatcaaagagatgagtgagagggagaagaaggagctgcagaaaatcttggaccgc
aagcggcacaacagcatcacagaggccaaatcccgggagaggcagaagaaggatgtggag
ctgaccgagattaacaggcgccacatcaacgagtccgtgaactccatccgcaggctggag
gaggcccagaagcggcgccaggagaagctggtgaccggacaccaggacatcctgcaacag
attgaggaagaggagcccaggctggtggagaagctggagcaggagtgcgagctggaggct
caggtgctgccccaggagatccgccgcttccttcaggccgagctggaggggggggtgagc
aacgggcacccccctgccgcccctcaggaagaggaggatgagaacacggtgctgtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (7)   
   Pfam (7)   
All databases (19)   

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