KEGG   Callorhinchus milii (elephant shark): 103171709
Entry
103171709         CDS       T03088                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
cmk  Callorhinchus milii (elephant shark)
Pathway
cmk00562  Inositol phosphate metabolism
cmk01100  Metabolic pathways
cmk04020  Calcium signaling pathway
cmk04070  Phosphatidylinositol signaling system
cmk04081  Hormone signaling
cmk04082  Neuroactive ligand signaling
cmk04261  Adrenergic signaling in cardiomyocytes
cmk04270  Vascular smooth muscle contraction
cmk04310  Wnt signaling pathway
cmk04371  Apelin signaling pathway
cmk04540  Gap junction
cmk04621  NOD-like receptor signaling pathway
cmk04912  GnRH signaling pathway
cmk04916  Melanogenesis
Module
cmk_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:cmk00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    103171709
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    103171709
   04371 Apelin signaling pathway
    103171709
   04020 Calcium signaling pathway
    103171709
   04070 Phosphatidylinositol signaling system
    103171709
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    103171709
   04081 Hormone signaling
    103171709
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    103171709
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    103171709
  09152 Endocrine system
   04912 GnRH signaling pathway
    103171709
   04916 Melanogenesis
    103171709
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103171709
   04270 Vascular smooth muscle contraction
    103171709
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cmk04131]
    103171709
Enzymes [BR:cmk01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     103171709
Membrane trafficking [BR:cmk04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    103171709
 Endocytosis
  Macropinocytosis
   Phospholipase C
    103171709
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y PH_14 PLCB1-4-like_EFh EF-hand_like C2 PLC-beta_C EF-hand_7 EF-hand_6
Other DBs
NCBI-GeneID: 103171709
NCBI-ProteinID: XP_042188773
UniProt: V9K9T0
Position
Unknown
AA seq 1213 aa
MAKAYEFLWQKSVPSFLQEGSVFDRYDEESSVCETQCTFKVDEFGFFLTWKSEGKEGQIL
ECSMINHIYYGVSTKDPKLLSALEGVGRGENELEGRVFNVCSGADLVNISFMYMVADHVE
TAKQWVEGLSAIVHNFRASSVCPMTCLKKHWMRLSFLTNVNGKIPVRSITRTFASGKTEK
VIFQALKELGLPSGKNDEIEPVVFTFDKFYALTQKICPRTDIEELFKKLNGDKTDYLTVD
QLVSFLNDNQRDPRLNEILFPFYDRKRVMQIFEHYDPDKELRQQGRMSFDGFCRYLMSDE
NTPVFLDRLELYQEMDQSLSHYFISSSHNTYLTGRQFGGKSSVEMYKQILLSGCRCIELD
IWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKDTAFVTSEFPVILSFENHCSKPQQYKM
AKYCEEIFGDFLLKVPLESFPLDKAQPLPSPNDLKRKILIKNKRLKPEVEHKQLETFKQL
MEGGESSSPASLLDDEIEEEIENADLSPISVDQDEEAHPELKFHSELSADPISQEKEVHV
NSVKKVIEDPEQDNKKGTITVEDEQAWVSSYTYVGATTNIHPYLSAMVNYAQPVKFQGFQ
VAEERNIHCNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWN
AGCQMVSLNFQTPDLAMQLNQGKFEYNGSCGYLLKPEFMRRPDRTFDPFSETPVDGVIAA
TCSVEVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEEAFVFRK
VILPDLAVLRIAVYDDNSRLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLK
TYVPDGFGDIVDALSDPKKFLSVMEKRADQMRAMGIETSDIADVPNDSSKNDKKGKSNMG
KSSVTPQLSSELRHNSTLGQGTGNNAKRDTAVISQVNIEDLKQMKPYLKLLKKQQKELSS
LKRKYSKEQSSTQKLHCVQVDRLVAQHDKEKLTHEKILDKAIKKKGESNCVDLKKETEMK
IQSLSSDHKMKMKQLVGQQTKEWSEMVNSHNAEEQELRDLHVMEQCDVLRKLLVSEHEQQ
TQQLKVIHDRLSKEMKANQAKSSMENSKAISQDKSIKNKAERERRVRELNSINTKKFLEE
RKRLAMKHVKEAEQLKKAQLEQLDGLEKQNEQLLKSCHEGSGTQGKRDAADGEAGGGDGP
QASHSGVKPPDTA
NT seq 3642 nt   +upstreamnt  +downstreamnt
atggcaaaagcatacgagtttctgtggcagaaatctgttccctctttcctacaagaaggg
tctgtgtttgacagatacgatgaggagtcttcggtgtgcgaaactcaatgtaccttcaaa
gtggatgagtttggattctttctcacgtggaagagtgaggggaaggaaggtcaaatcctg
gaatgttcaatgatcaaccacatttactatggtgtcagcaccaaggatcccaaactgctg
tctgctcttgagggagtggggcgaggtgagaacgagctggaagggcgggtattcaatgtg
tgttcaggagctgacctggtgaacatcagcttcatgtatatggtggcggatcatgtggag
acagctaagcaatgggtggaggggctgagtgccatcgttcacaacttcagagccagcagt
gtctgccccatgacctgtctcaagaaacactggatgaggttatcattcttgacaaatgta
aatggaaaaattccagtgaggagtataacgaggacctttgcgtcgggcaaaacagagaag
gtgatatttcaggccctgaaggagctggggctgcccagtgggaagaacgatgaaatcgag
cccgtggtgttcacctttgataaattctatgcactaacacaaaagatatgccctcgaact
gatattgaggagctcttcaagaaactcaacggagacaaaactgattacttaactgtagac
caattagtcagctttctcaatgacaaccagagagaccctcggctgaacgagatcctgttc
ccattctatgataggaaacgggtgatgcagatatttgagcattatgatcctgacaaagag
ctgaggcaacaagggcggatgtcgtttgacggcttctgcaggtacctgatgtctgatgag
aacacccctgtgttcctggaccggctggagctgtaccaagaaatggaccagtcactctct
cactacttcatcagctcctcacacaacacctacctgacaggcaggcagttcgggggcaaa
tcatcagtggagatgtacaagcaaatcctgctatcaggctgcaggtgtattgaattagat
atttgggatggaaaaggggaggatcaggagcccattataacacacggcaaagccatgtgt
acagacatcctcttcaaggatgtgattcaagccatcaaagatacagcgtttgtcacctct
gagtttcctgttatactttcgtttgaaaatcattgcagtaaaccgcagcagtacaagatg
gcaaagtattgtgaggagatttttggagacttcttactgaaggtgccgctcgagtccttt
ccgcttgacaaggcacaacctctgccatctcccaatgacctcaaaagaaaaatactgatc
aaaaataaaaggttaaagcctgaggtggagcacaagcaactggagacctttaagcagctg
atggagggcggggagagcagcagcccggccagcctgctggacgacgagatcgaggaagaa
atcgaaaacgctgacctgtctccgatatccgttgatcaggatgaagaggcccatcctgaa
ctcaagttccacagtgagctctccgctgaccccattagccaggagaaagaggtgcacgtc
aacagtgtgaagaaggtgatcgaagaccctgagcaggacaataagaagggcactatcaca
gtggaggacgagcaggcctgggtgtcgagctatacgtatgttggagccacgactaacatc
catccatacctgtcggccatggtcaactacgcccagcccgtcaagttccagggcttccag
gtagccgaagagaggaatattcactgcaacatgtcttcattcaatgaatcggtgggactg
ggatatctgaagactcacgcaatcgagtttgtgaactataataaacgtcaaatgagtcgt
atttaccctaagggaggccgagtggattccagtaattacatgcctcagatcttctggaac
gctggctgccagatggtctccctcaacttccagaccccagatttggccatgcagttgaac
cagggaaagtttgaatacaatggctcatgtgggtatctcctgaagccagaattcatgcgt
cgcccagaccggacctttgacccattctctgagaccccagtggacggggtcattgcagcc
acctgttctgtagaggtaatatccggccagtttttgtcggacaagaagattgggacctac
gtggaggtagacatgtacggtttgcccaccgacaccatccgcaaggagttccgcacccgc
atggtgatgaacaacggcttaaaccctgtgtataacgaggaggcctttgtattccggaag
gttatcttgcctgacctggctgtgctgaggatagcggtttatgacgacaacagccgactg
attggccagcggatcctgcctctggacgggctgcaggcgggttaccggcacatctccctg
agaaacgagggcaacaagccactctctctgcccaccgtcttctgtaacattgtcctcaaa
acctacgtccctgacggcttcggagacattgtggacgctctatcagacccaaagaagttc
ttgtcagtgatggagaagcgagctgaccagatgagggcaatgggaatcgaaactagcgac
attgcagacgtaccgaacgacagctccaagaatgacaagaaagggaagagtaacatgggc
aagagcagcgtgactccccagttgagctccgaactacggcacaactctacgttaggccaa
ggcactggcaacaatgccaagagagacacagcggtgatatctcaggttaacattgaggac
ctgaagcaaatgaagccctacttgaaattactgaagaagcaacaaaaggaattgagttcg
ctgaagagaaagtactccaaggagcagagctccactcagaagctccactgcgtacaggtg
gacagactggtggctcagcacgacaaggagaagctaacacacgagaagattttagacaaa
gccatcaagaaaaaaggggaaagcaactgtgttgatttgaagaaagaaacagagatgaaa
atccagtcactatcttcagaccacaagatgaagatgaagcagctggtgggccagcagacc
aaggaatggtctgagatggtgaacagtcataatgcggaggagcaggagctgcgggacctg
catgtgatggagcagtgcgatgtgctacgtaagctgctggtcagtgagcacgagcaacaa
acacagcagctcaaggtcatccacgacaggctcagcaaggagatgaaagccaaccaggcc
aagagctcgatggagaacagtaaagccatcagccaggacaagagcatcaaaaacaaggcg
gaaagagagagacgggtccgggaactgaacagcatcaacaccaaaaaattcctggaggag
aggaagcgacttgcaatgaaacacgtcaaggaagcggaacaactgaaaaaagctcaactt
gaacagctggatggtttggagaaacaaaacgaacagctgctgaaatcatgtcatgaaggg
tctggtactcaaggcaaaagagatgcggcggatggtgaagctggaggcggggatggcccg
caggcaagccacagtggtgtgaagcccccagacacagcctga

  All links  
Gene (21)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (6)   
   RefSeq(nuc) (4)   
   GenBank (1)   
   EMBL (1)   
Protein domain (9)   
   Pfam (9)   
All databases (41)   

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