KEGG   Chionomys nivalis (European snow vole): 130890476
Entry
130890476         CDS       T11437                                 
Symbol
Mapk14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
cnl  Chionomys nivalis (European snow vole)
Pathway
cnl01522  Endocrine resistance
cnl04010  MAPK signaling pathway
cnl04015  Rap1 signaling pathway
cnl04068  FoxO signaling pathway
cnl04071  Sphingolipid signaling pathway
cnl04114  Oocyte meiosis
cnl04148  Efferocytosis
cnl04218  Cellular senescence
cnl04261  Adrenergic signaling in cardiomyocytes
cnl04370  VEGF signaling pathway
cnl04380  Osteoclast differentiation
cnl04517  IgSF CAM signaling
cnl04519  Cadherin signaling
cnl04550  Signaling pathways regulating pluripotency of stem cells
cnl04611  Platelet activation
cnl04613  Neutrophil extracellular trap formation
cnl04620  Toll-like receptor signaling pathway
cnl04621  NOD-like receptor signaling pathway
cnl04622  RIG-I-like receptor signaling pathway
cnl04625  C-type lectin receptor signaling pathway
cnl04657  IL-17 signaling pathway
cnl04658  Th1 and Th2 cell differentiation
cnl04659  Th17 cell differentiation
cnl04660  T cell receptor signaling pathway
cnl04664  Fc epsilon RI signaling pathway
cnl04668  TNF signaling pathway
cnl04670  Leukocyte transendothelial migration
cnl04714  Thermogenesis
cnl04722  Neurotrophin signaling pathway
cnl04723  Retrograde endocannabinoid signaling
cnl04728  Dopaminergic synapse
cnl04750  Inflammatory mediator regulation of TRP channels
cnl04912  GnRH signaling pathway
cnl04914  Progesterone-mediated oocyte maturation
cnl04917  Prolactin signaling pathway
cnl04926  Relaxin signaling pathway
cnl04932  Non-alcoholic fatty liver disease
cnl04933  AGE-RAGE signaling pathway in diabetic complications
cnl04935  Growth hormone synthesis, secretion and action
cnl04936  Alcoholic liver disease
cnl05014  Amyotrophic lateral sclerosis
cnl05020  Prion disease
cnl05022  Pathways of neurodegeneration - multiple diseases
cnl05132  Salmonella infection
cnl05133  Pertussis
cnl05135  Yersinia infection
cnl05140  Leishmaniasis
cnl05142  Chagas disease
cnl05145  Toxoplasmosis
cnl05152  Tuberculosis
cnl05161  Hepatitis B
cnl05163  Human cytomegalovirus infection
cnl05167  Kaposi sarcoma-associated herpesvirus infection
cnl05169  Epstein-Barr virus infection
cnl05170  Human immunodeficiency virus 1 infection
cnl05171  Coronavirus disease
cnl05205  Proteoglycans in cancer
cnl05208  Chemical carcinogenesis - reactive oxygen species
cnl05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cnl05415  Diabetic cardiomyopathy
cnl05417  Lipid and atherosclerosis
cnl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cnl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    130890476 (Mapk14)
   04015 Rap1 signaling pathway
    130890476 (Mapk14)
   04370 VEGF signaling pathway
    130890476 (Mapk14)
   04668 TNF signaling pathway
    130890476 (Mapk14)
   04068 FoxO signaling pathway
    130890476 (Mapk14)
   04071 Sphingolipid signaling pathway
    130890476 (Mapk14)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    130890476 (Mapk14)
   04519 Cadherin signaling
    130890476 (Mapk14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    130890476 (Mapk14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    130890476 (Mapk14)
   04218 Cellular senescence
    130890476 (Mapk14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    130890476 (Mapk14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    130890476 (Mapk14)
   04613 Neutrophil extracellular trap formation
    130890476 (Mapk14)
   04620 Toll-like receptor signaling pathway
    130890476 (Mapk14)
   04621 NOD-like receptor signaling pathway
    130890476 (Mapk14)
   04622 RIG-I-like receptor signaling pathway
    130890476 (Mapk14)
   04625 C-type lectin receptor signaling pathway
    130890476 (Mapk14)
   04660 T cell receptor signaling pathway
    130890476 (Mapk14)
   04658 Th1 and Th2 cell differentiation
    130890476 (Mapk14)
   04659 Th17 cell differentiation
    130890476 (Mapk14)
   04657 IL-17 signaling pathway
    130890476 (Mapk14)
   04664 Fc epsilon RI signaling pathway
    130890476 (Mapk14)
   04670 Leukocyte transendothelial migration
    130890476 (Mapk14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    130890476 (Mapk14)
   04914 Progesterone-mediated oocyte maturation
    130890476 (Mapk14)
   04917 Prolactin signaling pathway
    130890476 (Mapk14)
   04926 Relaxin signaling pathway
    130890476 (Mapk14)
   04935 Growth hormone synthesis, secretion and action
    130890476 (Mapk14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    130890476 (Mapk14)
  09156 Nervous system
   04728 Dopaminergic synapse
    130890476 (Mapk14)
   04723 Retrograde endocannabinoid signaling
    130890476 (Mapk14)
   04722 Neurotrophin signaling pathway
    130890476 (Mapk14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    130890476 (Mapk14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    130890476 (Mapk14)
  09159 Environmental adaptation
   04714 Thermogenesis
    130890476 (Mapk14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    130890476 (Mapk14)
   05208 Chemical carcinogenesis - reactive oxygen species
    130890476 (Mapk14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    130890476 (Mapk14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    130890476 (Mapk14)
   05161 Hepatitis B
    130890476 (Mapk14)
   05171 Coronavirus disease
    130890476 (Mapk14)
   05163 Human cytomegalovirus infection
    130890476 (Mapk14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    130890476 (Mapk14)
   05169 Epstein-Barr virus infection
    130890476 (Mapk14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    130890476 (Mapk14)
   05135 Yersinia infection
    130890476 (Mapk14)
   05133 Pertussis
    130890476 (Mapk14)
   05152 Tuberculosis
    130890476 (Mapk14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    130890476 (Mapk14)
   05140 Leishmaniasis
    130890476 (Mapk14)
   05142 Chagas disease
    130890476 (Mapk14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    130890476 (Mapk14)
   05020 Prion disease
    130890476 (Mapk14)
   05022 Pathways of neurodegeneration - multiple diseases
    130890476 (Mapk14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    130890476 (Mapk14)
   05418 Fluid shear stress and atherosclerosis
    130890476 (Mapk14)
   05415 Diabetic cardiomyopathy
    130890476 (Mapk14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    130890476 (Mapk14)
   04932 Non-alcoholic fatty liver disease
    130890476 (Mapk14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    130890476 (Mapk14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    130890476 (Mapk14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cnl01001]
    130890476 (Mapk14)
Enzymes [BR:cnl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     130890476 (Mapk14)
Protein kinases [BR:cnl01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   130890476 (Mapk14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 130890476
NCBI-ProteinID: XP_057650394
Position
19:complement(59352866..59414846)
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaggagctgaacaagaccatctgggaggtg
cccgagcgataccagaacctgtccccggtgggctcgggcgcctatggctcggtttgtgct
gcttttgatacaaagacaggacatcgtgtggcagtgaagaagctgtcaagaccgtttcag
tccatcattcatgccaaaaggacctacagagagctgcgcctgctgaagcacatgaaacac
gagaatgtcattggtctgttggatgtgtttacgcccgcgaggtccctggaggaattcaat
gatgtgtacctggtgacgcatctcatgggggcagacctaaacaacattgtgaagtgtcag
aagcttactgatgaccacgttcagttcctcatctaccagatcctccgaggactgaagtac
atacattcagctgacataattcacagggacctgaaacctagtaacctagctgtgaatgag
gactgtgagctgaagattctggattttggactggctcggcatactgatgatgaaatgaca
ggctacgtggctaccaggtggtacagggctcctgagatcatgctgaactggatgcactac
aaccagacagtggatatttggtccgtgggctgcatcatggctgagctgttgaccggaaga
acgctgtttcctggtacagaccatattgatcagttgaaactcattttaagactcgttgga
accccaggggctgagcttctgaagaaaatctcctcagagtctgcaagaaactacattcag
tccctggcccagatgccgaagatgaactttgcaaatgtgtttattggcgccaaccccctg
gctgtggacctgctggagaagatgctcgtcctggactcagataagaggatcacggcagcc
caagccctggcacatgcctacttcgctcagtaccacgaccctgatgacgagcctgtggcc
gacccttacgaccagtccttcgaaagcagggacctcctaatagatgagtggaaaagcctg
acctacgatgaagtcatcagctttgtgccaccgccccttgaccaagaagaaatggagtcc
tga

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