KEGG   Chlorocebus sabaeus (green monkey): 103223553
Entry
103223553         CDS       T04361                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
csab  Chlorocebus sabaeus (green monkey)
Pathway
csab01522  Endocrine resistance
csab04010  MAPK signaling pathway
csab04015  Rap1 signaling pathway
csab04068  FoxO signaling pathway
csab04071  Sphingolipid signaling pathway
csab04114  Oocyte meiosis
csab04148  Efferocytosis
csab04218  Cellular senescence
csab04261  Adrenergic signaling in cardiomyocytes
csab04370  VEGF signaling pathway
csab04380  Osteoclast differentiation
csab04517  IgSF CAM signaling
csab04519  Cadherin signaling
csab04550  Signaling pathways regulating pluripotency of stem cells
csab04611  Platelet activation
csab04613  Neutrophil extracellular trap formation
csab04620  Toll-like receptor signaling pathway
csab04621  NOD-like receptor signaling pathway
csab04622  RIG-I-like receptor signaling pathway
csab04625  C-type lectin receptor signaling pathway
csab04657  IL-17 signaling pathway
csab04658  Th1 and Th2 cell differentiation
csab04659  Th17 cell differentiation
csab04660  T cell receptor signaling pathway
csab04664  Fc epsilon RI signaling pathway
csab04668  TNF signaling pathway
csab04670  Leukocyte transendothelial migration
csab04714  Thermogenesis
csab04722  Neurotrophin signaling pathway
csab04723  Retrograde endocannabinoid signaling
csab04728  Dopaminergic synapse
csab04750  Inflammatory mediator regulation of TRP channels
csab04912  GnRH signaling pathway
csab04914  Progesterone-mediated oocyte maturation
csab04917  Prolactin signaling pathway
csab04926  Relaxin signaling pathway
csab04932  Non-alcoholic fatty liver disease
csab04933  AGE-RAGE signaling pathway in diabetic complications
csab04935  Growth hormone synthesis, secretion and action
csab04936  Alcoholic liver disease
csab05014  Amyotrophic lateral sclerosis
csab05020  Prion disease
csab05022  Pathways of neurodegeneration - multiple diseases
csab05132  Salmonella infection
csab05133  Pertussis
csab05135  Yersinia infection
csab05140  Leishmaniasis
csab05142  Chagas disease
csab05145  Toxoplasmosis
csab05152  Tuberculosis
csab05161  Hepatitis B
csab05163  Human cytomegalovirus infection
csab05167  Kaposi sarcoma-associated herpesvirus infection
csab05169  Epstein-Barr virus infection
csab05170  Human immunodeficiency virus 1 infection
csab05171  Coronavirus disease
csab05205  Proteoglycans in cancer
csab05208  Chemical carcinogenesis - reactive oxygen species
csab05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
csab05415  Diabetic cardiomyopathy
csab05417  Lipid and atherosclerosis
csab05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:csab00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103223553 (MAPK12)
   04015 Rap1 signaling pathway
    103223553 (MAPK12)
   04370 VEGF signaling pathway
    103223553 (MAPK12)
   04668 TNF signaling pathway
    103223553 (MAPK12)
   04068 FoxO signaling pathway
    103223553 (MAPK12)
   04071 Sphingolipid signaling pathway
    103223553 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    103223553 (MAPK12)
   04519 Cadherin signaling
    103223553 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    103223553 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    103223553 (MAPK12)
   04218 Cellular senescence
    103223553 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    103223553 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103223553 (MAPK12)
   04613 Neutrophil extracellular trap formation
    103223553 (MAPK12)
   04620 Toll-like receptor signaling pathway
    103223553 (MAPK12)
   04621 NOD-like receptor signaling pathway
    103223553 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    103223553 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    103223553 (MAPK12)
   04660 T cell receptor signaling pathway
    103223553 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    103223553 (MAPK12)
   04659 Th17 cell differentiation
    103223553 (MAPK12)
   04657 IL-17 signaling pathway
    103223553 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    103223553 (MAPK12)
   04670 Leukocyte transendothelial migration
    103223553 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103223553 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    103223553 (MAPK12)
   04917 Prolactin signaling pathway
    103223553 (MAPK12)
   04926 Relaxin signaling pathway
    103223553 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    103223553 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103223553 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    103223553 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    103223553 (MAPK12)
   04722 Neurotrophin signaling pathway
    103223553 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103223553 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103223553 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    103223553 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103223553 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    103223553 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103223553 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103223553 (MAPK12)
   05161 Hepatitis B
    103223553 (MAPK12)
   05171 Coronavirus disease
    103223553 (MAPK12)
   05163 Human cytomegalovirus infection
    103223553 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103223553 (MAPK12)
   05169 Epstein-Barr virus infection
    103223553 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103223553 (MAPK12)
   05135 Yersinia infection
    103223553 (MAPK12)
   05133 Pertussis
    103223553 (MAPK12)
   05152 Tuberculosis
    103223553 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103223553 (MAPK12)
   05140 Leishmaniasis
    103223553 (MAPK12)
   05142 Chagas disease
    103223553 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103223553 (MAPK12)
   05020 Prion disease
    103223553 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    103223553 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103223553 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    103223553 (MAPK12)
   05415 Diabetic cardiomyopathy
    103223553 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103223553 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    103223553 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103223553 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103223553 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:csab01001]
    103223553 (MAPK12)
Enzymes [BR:csab01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     103223553 (MAPK12)
Protein kinases [BR:csab01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   103223553 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1
Other DBs
NCBI-GeneID: 103223553
NCBI-ProteinID: XP_007974385
Position
19:complement(32742625..32754152)
AA seq 654 aa
MGPAPWNHGQSGLEPRVSAGAPPSPGSTPRLGKFSQRGEADRGISAPRPALGRDKAAGRR
SPPPALPPRLRPSPGGRRLGFPEGPEGGRGRHVRAARGPVGPRAGEGPCAAWVGVGPGSA
PGTSPREGPGAGASQRWAGEQRGVGPGRTPRKSRRSRVPGPGAQPAGSAGWAAPGPAMSS
PPPARSGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYRPFQ
SELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHE
KLGEDRIQFLVYQMLKGLRYIHAAGIIHRVSPGAGATHQPSPSAIPRLHVLPDLKPGNLA
VNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMI
TGKTLFKGSDRILQQQGSTRGGADLDQLKEIMKVTGTPPAEFVQRLQSDEAKNYMKGLPE
LEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAAEALAHPYFESLHDTEDEPQVQKYD
DSFDDVDRTLDEWKRELGAPGRACVDPSWGLWAGPVLTHKWGDPGRACVDPSRRLQAGPV
WTCEWGALGRACVDPVGPVPVARLRVLDPCPWDAGQVRRMGGQRAAWGRVAWWK
NT seq 1965 nt   +upstreamnt  +downstreamnt
atgggccctgcgccctggaaccatgggcagtcaggactggagcccagggtctcagcagga
gctcccccctcccccggctccacccccagattggggaagttcagccaaaggggagaggct
gacaggggtatctccgcgccgcgtccggccctaggtcgggacaaagctgccgggcggcgc
tcccctccccctgcgcttccccccaggctccggccctcccccggcggccgccgcctcggg
tttccggaggggccggagggcgggcgagggcgtcacgtgcgcgccgcccgcgggccggtt
ggtccccgggcgggggaggggccgtgcgctgcctgggtcggggtcgggccagggtcggca
cctgggacatccccgagggaagggccgggagcaggagcgtcccagcggtgggcgggcgag
cagcgcggagtcggcccggggcgcacgccgaggaagtcccgccgatcccgggtccccggt
ccgggggcacagcccgcgggctctgcggggtgggcggctcccgggcctgccatgagctct
ccaccgcctgcccgcagtggcttttaccgccaggaggtgaccaagacggcctgggaggtg
cgcgccgtgtaccgggacctgcagcccgtgggctcgggcgcctatggcgcggtgtgctcg
gccgtggacagccgcaccggcgctaaggtggccatcaagaagctgtatcggcccttccag
tccgagctgttcgccaagcgcgcctaccgcgagctgcgcctgctcaagcacatgcgccac
gagaacgtgattgggctgctggacgtattcactcctgacgagaccctggatgacttcaca
gacttttacctggtgatgccattcatgggcaccgacctgggcaagctcatgaaacatgag
aagctgggcgaggaccggatccagttcctcgtgtaccagatgctgaaggggctgaggtat
atccatgctgccggcatcatccacagagtgagtcctggtgcaggagccacccatcagccc
tcccccagcgcaatcccccgcctccacgtcctacctgacctgaagcctggcaacctggct
gtgaacgaagactgtgagctgaagatcctggactttggcctggccaggcaggcagatagc
gagatgactggctatgtggtgacccggtggtaccgggcacccgaggtcatcttgaattgg
atgcgctacacgcagacggtggacatctggtctgtggggtgcatcatggcggagatgatc
acaggcaagacgctgtttaagggcagcgaccgtatcctccagcagcagggcagcaccagg
ggcggtgcagacctggaccagctgaaggagatcatgaaagtgacagggacgcctccagct
gagtttgtgcagcggctgcagagtgatgaggccaagaactacatgaagggcctccctgag
ttggagaagaaggattttgcctccatcctgaccaatgcaagccctctggctgtgaacctc
ctggagaagatgctggtgctggatgcggagcagcgggtgacggcagccgaggcactggcc
catccctacttcgagtccctgcacgacacagaagatgagccccaggtccagaagtatgac
gactcctttgatgacgtggaccgcacgctggatgaatggaagcgtgagctgggggctcca
ggcagggcctgtgtggacccgagttgggggctctgggcagggcctgtgttgacccataag
tggggggatcctggcagggcctgtgtggacccgagtaggaggctccaggcagggcctgtg
tggacctgtgagtggggggctctgggcagggcctgtgtggaccctgtgggccctgtgccg
gtggccaggctcagagtcctagatccctgtccctgggatgcaggtcaggtgaggagaatg
ggaggtcagagggcagcatggggccgtgtggcctggtggaaatga

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (8)   
   RefSeq(pep) (8)   
DNA sequence (8)   
   RefSeq(nuc) (8)   
Protein domain (3)   
   Pfam (3)   
All databases (22)   

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