KEGG   Crotalus tigris (Tiger rattlesnake): 120315294
Entry
120315294         CDS       T08476                                 
Symbol
PLCB4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ctig  Crotalus tigris (Tiger rattlesnake)
Pathway
ctig00562  Inositol phosphate metabolism
ctig01100  Metabolic pathways
ctig04020  Calcium signaling pathway
ctig04070  Phosphatidylinositol signaling system
ctig04081  Hormone signaling
ctig04082  Neuroactive ligand signaling
ctig04261  Adrenergic signaling in cardiomyocytes
ctig04270  Vascular smooth muscle contraction
ctig04310  Wnt signaling pathway
ctig04371  Apelin signaling pathway
ctig04540  Gap junction
ctig04621  NOD-like receptor signaling pathway
ctig04912  GnRH signaling pathway
ctig04916  Melanogenesis
Module
ctig_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ctig00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    120315294 (PLCB4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    120315294 (PLCB4)
   04371 Apelin signaling pathway
    120315294 (PLCB4)
   04020 Calcium signaling pathway
    120315294 (PLCB4)
   04070 Phosphatidylinositol signaling system
    120315294 (PLCB4)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    120315294 (PLCB4)
   04081 Hormone signaling
    120315294 (PLCB4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    120315294 (PLCB4)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    120315294 (PLCB4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    120315294 (PLCB4)
   04916 Melanogenesis
    120315294 (PLCB4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    120315294 (PLCB4)
   04270 Vascular smooth muscle contraction
    120315294 (PLCB4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ctig04131]
    120315294 (PLCB4)
Enzymes [BR:ctig01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     120315294 (PLCB4)
Membrane trafficking [BR:ctig04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    120315294 (PLCB4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    120315294 (PLCB4)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2 PLC-beta_C EF-hand_7 EF-hand_6
Other DBs
NCBI-GeneID: 120315294
NCBI-ProteinID: XP_039215346
Position
Unknown
AA seq 1292 aa
MAKPYEFNWQKSVPSFLQDGAIFDRYEEESSVFEPSCLFKVDEFGFFLSWKSEGKEGQVL
ECSLINSIRFGAIPKDPKILAALEAVSKAENELEGRIICVCSGTDLVNINFTYIVAESTE
DAKQWVDGLRSVMGNFRANNVCPTTCLKKHWMKLAFLTNTNGKIPVRSITRTFASGKTEK
VIFQALKELGLPSGKNDEIEPSAFTFEKFYELTQKICPRTDIEELFRKINGDKTDYLTVD
QLVSFLNEHQRDPRLNEILFPFFDPKRAMQIIEIYEPDEDLKKKGVMSSDGFCRYLMSDE
NAPVFLDRLELYQEMEHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCIELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM
SKYCEDIFGDLLLKQPLETHPLEPGRSLPSPNDLRKKILIKNKRLKPEVEKKQLETLKSM
MEAGETAAPVSILEDDNEEEIESGEQEEEAHPEYKFGSELSADDLSQKESVANHIKKAVD
DSEQENNKKGVITAEDEQAWMASYKYVGATTNIHPYLSTLINYAQPVKFQGFSVAEERNI
HYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVS
LNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVI
SGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEECFVFRKVILPDLA
VLRIAVYDDNNRLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGF
GDIVDALSDPKKFLSVMEKRADQMRAMGIETSDIADVPNDTSKNDKKGKTNNAKANVTPQ
TSSEVRSNPISSTGPGTEIKKGIDLIPQIKIEDLKQMKAYIKHLKKQQKELTALKKRHAK
EHSIMQKLHCTQVDKMVAQYDKEKLAYEKLLEKAIKKKGGNNCLEMKKETECKVQMLTSD
HKSKVKEIVAQHTKEWSEMINTHSAEEQEMRDLHLSQQCELLKKLLINVHEQQTQQLKLS
HDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMK
QSKEMDQLKKVQLEHLEILEKQNEQLLKSCHAVSQIQGGENHAHKKLHLQAVPEALLYLV
IEWLLDGGSLNSFGKNQLLNYVTMASISKEVVLFCQCIVLQLWAFSIMFWLEMAFICPFW
LFSRKNHIYSICSKYLDLYLIGEELYLPSINK
NT seq 3879 nt   +upstreamnt  +downstreamnt
atggcaaaaccatatgaatttaattggcagaagtcagtgccttcctttctacaggatgga
gctatttttgacagatacgaagaggaatcttctgtttttgagccaagctgcctgtttaaa
gttgatgaatttggcttttttctatcatggaaaagtgaaggaaaggaagggcaagtttta
gaatgttccctgatcaacagtattcgttttggagcaataccaaaggatccaaaaatatta
gctgctcttgaggctgtcagtaaagcagaaaatgaacttgaagggcgaataatttgtgtc
tgtagtggcactgatctggtgaacatcaacttcacatacattgtagcagaaagcactgaa
gacgctaagcaatgggttgatggactcagatcagttatgggtaacttcagagccaacaat
gtctgtcccacgacatgcctcaagaaacactggatgaaattggcatttctgactaatact
aatggcaaaattccagttagaagcattactagaacgtttgcgtcaggtaaaactgaaaaa
gtgatatttcaggcacttaaagaattgggtcttcccagtggaaagaatgatgaaatagag
ccttcagcttttacttttgagaagttttatgaactgacccagaagatatgtcctcgtact
gatatagaggagctttttagaaaaatcaatggagacaaaacagattatttaacggtagac
caattagtgagctttctaaatgaacatcaacgagatcctcggctgaatgaaattttattt
ccgttctttgatcctaaaagagcaatgcagataattgaaatatatgaaccagatgaagat
ttgaaaaagaaaggtgtcatgtcaagtgatgggttttgtcggtacttaatgtcagatgag
aatgcccctgtcttcctagaccgtttagagctgtatcaagaaatggaacaccctctggct
cactattttattagctcttcccacaacacatatctcacaggaaggcagtttggtggaaag
tcatcagtggagatgtacagacaagtcctcttggctggatgcaggtgtattgaacttgat
tgctgggatggaaaaggtgaagatcaagaaccaataataacacatggaaaggccatgtgt
acagatattctgttcaaggatgtgattcaagccattaaggaaacagcctttgtaacatct
gagtatcctgtcatcttgtcctttgaaaatcactgcagcaaataccaacaatacaaaatg
tcaaaatactgcgaagatatttttggagatcttctcctaaagcagccactagaaacacat
ccacttgaaccaggaaggtccttgccctccccaaatgatctgagaaaaaagattcttatt
aaaaacaaaaggttgaaaccagaggtggaaaaaaaacagcttgaaactttgaaaagtatg
atggaagctggtgaaacggctgctcctgtcagcatcttggaagatgataatgaagaggag
atagaaagtggggagcaagaagaggaagcgcatccagagtataaatttggaagtgagctt
tctgcagatgacctgagccaaaaggaatctgtagctaatcacattaaaaaggctgtggac
gattctgaacaagaaaacaataaaaagggtgtgataactgcagaagatgaacaagcatgg
atggcttcttataaatatgtaggtgccacaactaatatacacccgtacttgtcaacattg
atcaactacgctcagcctgttaaatttcaaggtttcagtgtagcagaagaacgcaacatt
cactacaacatgtcctcttttaatgagtctgtcgggttgggctatttgaagacccacgca
attgaatttgtgaactacaataagcggcaaatgagtcggatatacccaaagggaggcaga
gtagattccagcaattacatgcctcaaattttctggaacgctggatgccagatggtctcc
cttaactatcagaccccagatctagcaatgcagttgaatcaggggaaatttgagtataat
gggtcttgtggttatcttcttaaaccagatttcatgcggcgtcctgatcggacatttgac
cctttttctgagactcctgtggatggtgttattgcagcgacttgttcagtgcaggtcata
tctggtcaatttttatcagacaaaaaaattggtacttacgtagaggtggatatgtatggt
cttcccactgatacaatacgtaaggaattccgaacacggatggtgatgaacaatggctta
aatcctgtttacaacgaagagtgctttgtgttccgaaaggtgattctaccagatcttgcc
gtcttgaggatagcagtttatgatgacaacaacaggttgattggtcaaaggatattgcca
ctggatgggcttcaggcaggctatcgacacatttcccttcgaaatgaaggcaacaagcca
ttgtctctgccaacagttttctgcaacattgtacttaaaacttacgtgcctgatggtttt
ggagatattgtggatgccttgtcagatccaaagaaatttttatctgtcatggagaaaaga
gcagaccagatgagagctatgggaattgaaacgagtgacatagctgatgttccaaatgac
acatcgaagaatgataagaaggggaaaactaataatgctaaagcaaatgttactcctcag
accagttctgaagtcagatcaaatcccatttccagtacaggacctggtacagagattaag
aaaggtatcgatcttattcctcaaatcaagatagaagacttaaaacagatgaaggcatat
ataaagcatttgaaaaaacagcaaaaagagctgactgctttgaagaagaggcatgccaag
gagcacagcatcatgcagaagttacactgtacacaagttgacaaaatggtagcccagtat
gacaaagagaagctagcttatgagaaactccttgagaaagcaatcaagaaaaaaggagga
aataattgtcttgagatgaaaaaagaaacagaatgtaaagttcagatgttaacgtctgat
cataaatcaaaggtgaaggaaattgtggcgcagcacaccaaagagtggtccgagatgatc
aacacccacagcgcagaagagcaagaaatgcgtgatctgcaccttagccagcagtgtgaa
ctactgaagaagctgttaattaatgtgcatgaacagcagacacaacaactgaagctttcc
catgacagagaaagtaaagaaatgcgtgccaaccaagcaaaaatttcaatggaaaacagt
aaagccataagccaagataaatctatcaaaaacaaagctgaaagagaaaggcgggtgagg
gagctgaatagcagtaatacaaagaagtttctggaagaaagaaaacggttggcaatgaag
caatcaaaggaaatggatcagttgaagaaagtccaacttgagcatctagaaattttggag
aaacaaaatgagcagcttttgaaatcctgccatgcagtctctcaaattcaaggtggtgaa
aatcatgcccacaagaaactccatcttcaagcagttcctgaagccctgctttacttagtc
attgaatggcttttagatggaggatctctgaattcatttggaaaaaatcagctgttgaat
tatgtcacaatggccagtatttcaaaggaggttgtacttttctgtcaatgcattgtgctc
cagctttgggctttttcgattatgttttggcttgaaatggcattcatttgccctttctgg
ttgttttccagaaagaaccatatttatagcatctgctctaaatacttagatttgtatttg
atcggtgaagaattatatttgcctagtataaataaatag

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (12)   
   RefSeq(pep) (12)   
DNA sequence (14)   
   RefSeq(nuc) (14)   
Protein domain (9)   
   Pfam (9)   
All databases (37)   

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