KEGG   Cuculus canorus (common cuckoo): 104064431
Entry
104064431         CDS       T08597                                 
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
cuca  Cuculus canorus (common cuckoo)
Pathway
cuca00562  Inositol phosphate metabolism
cuca01100  Metabolic pathways
cuca04020  Calcium signaling pathway
cuca04070  Phosphatidylinositol signaling system
cuca04081  Hormone signaling
cuca04082  Neuroactive ligand signaling
cuca04261  Adrenergic signaling in cardiomyocytes
cuca04270  Vascular smooth muscle contraction
cuca04310  Wnt signaling pathway
cuca04371  Apelin signaling pathway
cuca04540  Gap junction
cuca04621  NOD-like receptor signaling pathway
cuca04912  GnRH signaling pathway
cuca04916  Melanogenesis
Module
cuca_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:cuca00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    104064431 (PLCB2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    104064431 (PLCB2)
   04371 Apelin signaling pathway
    104064431 (PLCB2)
   04020 Calcium signaling pathway
    104064431 (PLCB2)
   04070 Phosphatidylinositol signaling system
    104064431 (PLCB2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    104064431 (PLCB2)
   04081 Hormone signaling
    104064431 (PLCB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    104064431 (PLCB2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    104064431 (PLCB2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    104064431 (PLCB2)
   04916 Melanogenesis
    104064431 (PLCB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    104064431 (PLCB2)
   04270 Vascular smooth muscle contraction
    104064431 (PLCB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cuca04131]
    104064431 (PLCB2)
Enzymes [BR:cuca01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     104064431 (PLCB2)
Membrane trafficking [BR:cuca04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    104064431 (PLCB2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    104064431 (PLCB2)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2 M157_N_1 Peptidase_S46
Other DBs
NCBI-GeneID: 104064431
NCBI-ProteinID: XP_009565061
Position
5
AA seq 1207 aa
MSMLTPVLQPPEVKEYLSKGERFIKWDDETASASPVILRVDPKGFYVYWTHQNKEMEILD
ITSIRDTRVGRFAKIPKCQKLREVFNLDYPHSTFLLKTLTIVSGPDMVDLTFHNFVSYKE
NVGKSWAEDIMAIVRNPLTYNASRYTFLEKILVKLKMQLNAEGKIPVRNIFQMFPADRKR
VEAALSACHLPKGKNDAINPEDFPETVYKTFLMNLCPRPEIDEIFTSHHLKAKPYMTKEH
LAKFINKKQRDSRLNDILFPPAKPEQVQSLIEKYEPSGINIQRGQLSPEGMVWFLCGPEN
NVIALDKLLLYQDMTQPLSHYFINSSHNTYLTAGQFSGISSPEMYRQTLLAGCRCVELDC
WKGRPPDEEPIITHGFTMTTEILFKDAIEAIAESAFKTSLYPVILSFENHVDSPKQQAKM
AEYCRTIFGDMLLTEPLEKYPLKPGVPLPSPKDLLGKILIKNKKNQSISGKRQSSLKKGR
NVEPEIIEQPSPMDAEDTVWAGDVAEEEPEEEEDPLRNLDEEQIKKMQSDEGTAGLEVTA
YEEMSSLVNYIQPIKFDSFEVSAQKNRSYVISSFTELKAYDLLTKFPVQFVEYNKRQMSR
IYPKGTRMDSSNYMPQMFWNVGCQMVALNFQTMDVPMQQNMALFEFNGQCGYLLKHEFMR
RPDKQFDPFSVDRIDVVVASTLSVTILSGQFLSDRSVKTYVEVELFGLPRDTKRKYRTKL
TSTANSINPVWKEEAFVFEKIMMPELASLKIVAWEEGGKFIGHRVIPVIAVHSGYHHVCL
RSESNMPLTMPSLFVYLEVKDYVPDAWADLTIALSNPIKFFSLQDKRSVKLKDGSVERLG
PQRNLPSAESNGIPDSAGRCSFPVSNGPAGAAAFTKDESAIEATQIAEPQTASIAELQQM
KLFLKLLKKQEKELRELERKGCKRREELLQKYSVLFSEPLCYGGKKRMINSRKTQKKRSL
TTGDVGTCANPVEMAESQVLELRERLEMDLTHLGEEHYDGIRRKKEQHATEQVTKIIELA
REKQATELKALKESLESNIKDIKKKLEAKRVDRIQAVMRSTSNKAAQERLKKEINNSHIQ
EVVQTIKLVTEKTDRYQQKLEEKQAENLRAIKEKESQLQQEALVEYEEKLKRLSMEVQEM
VKNYARGSFPGEPEAQKDAVQSIPEGEQGPTDQLEEKILVAEVSRLTFTVPGPPGAETDV
EIEESIF
NT seq 3624 nt   +upstreamnt  +downstreamnt
atgtcgatgctgacccctgttctgcagcccccagaggtgaaggagtatctgtccaagggt
gagcgcttcatcaagtgggatgatgaaacggcaagcgcttctcctgtgattcttcgagtg
gatccaaagggcttctacgtgtactggacccatcagaacaaggaaatggaaattttggac
atcaccagcatccgagacacccgagtagggcgattcgccaagatccccaagtgccagaag
ctccgagaggtttttaacttggattaccctcacagcaccttcctgcttaagacactgact
attgtatccggccctgacatggtggacctcactttccataacttcgtgtcctacaaggag
aacgttggcaagagctgggctgaggatatcatggccatcgttcggaatcccctcacctac
aatgcttctcggtacaccttcctggagaaaatcctggtgaagctgaagatgcagcttaat
gcagaggggaagattcctgtcaggaatatttttcagatgtttcctgcggacaggaagagg
gtggaagcagcattaagcgcttgtcatcttcccaagggcaagaacgatgccatcaaccct
gaggacttccccgagactgtctataaaaccttcctcatgaatctgtgcccacggcctgag
attgatgagattttcacgtcgcaccatttaaaagcaaagccctacatgaccaaagagcac
ttggcaaagttcatcaacaagaagcagcgagactctcgcctcaatgacatcctcttccca
ccagccaaacccgagcaggtgcagagcctgatagagaagtatgagcccagcgggatcaac
atccagagagggcagttgtctccagaggggatggtctggttcctgtgtggccctgagaac
aacgtgatagcactggacaaattactgctgtatcaggacatgacccagccgctctcacac
tacttcatcaattcatcacacaacacctatttaacagccgggcagttctccggtatctcg
tctcctgaaatgtatcgccagacgctgctggccggctgccgctgtgtggagctggattgc
tggaaaggccgtcccccagatgaggagcccatcatcactcacgggttcaccatgaccact
gagatcctcttcaaggatgccattgaggccatcgcagaaagtgcttttaaaacatctctc
taccctgtcatcctgtccttcgagaaccatgtggactcgcccaagcagcaggcgaagatg
gctgagtactgccgaaccatctttggagatatgctgctgacagagccgctggagaagtac
ccgctgaagccaggagttcctcttccaagtcctaaggacctcttagggaagatcttgatt
aagaacaaaaagaaccaatcgatatctgggaagaggcagagctctttgaagaaagggagg
aacgtggaaccagagatcatcgagcaaccatcccctatggatgctgaagataccgtctgg
gcaggtgacgtggctgaagaggaaccagaggaagaggaggatcctctcagaaacctggat
gaagagcaaattaagaagatgcagtcagatgagggcaccgctggtttggaagtgacagca
tacgaggagatgtctagcctggttaattacatacagccaatcaaatttgactcttttgaa
gtctctgcccagaagaaccggagctacgtaatctcttccttcactgagctgaaggcttat
gatctgctaaccaagttcccagtgcagtttgtagaatacaacaagcgacagatgagccgg
atctaccccaaaggcacacggatggactcctccaattacatgcctcagatgttctggaat
gtcggctgtcagatggtggccctcaacttccagaccatggatgtccccatgcagcagaac
atggctctctttgagttcaacggccagtgtgggtatctgctcaagcacgaattcatgcgg
cgcccagacaagcagtttgaccccttctccgtggaccgcattgatgtggtggtggcaagt
accctgtctgtcacgatactttctggtcagttcctctcagaccgcagtgtgaagacatat
gtggaagtggagctgtttgggttgcccagggacacaaaacgcaaatacagaaccaaactg
acctccactgccaactccattaaccctgtgtggaaagaggaggcttttgtttttgaaaag
atcatgatgcctgagttggcatctcttaaaattgtggcctgggaggaaggagggaagttc
attggccatcgtgtcatccctgttattgcagtgcattcaggctaccaccacgtttgtctc
cgcagcgaaagcaacatgccactcaccatgccttctctgtttgtgtacctggaagtaaag
gactacgttcccgacgcttgggcagatctgaccattgctctctccaaccccattaagttc
ttcagcctgcaagacaagagatccgttaagctaaaggatggctcagtggagaggcttggc
ccacaaaggaacctcccatctgctgaaagtaacgggataccagactctgctgggagatgc
agctttcctgtttcaaatgggcctgcaggagcagcggctttcaccaaggatgaaagtgca
atagaagcaacgcagattgcagagcctcagacagcaagcatcgcggagctgcagcagatg
aagctctttctgaagctgctgaagaaacaggagaaggaactgagggagctggagcggaaa
ggatgtaaacggagggaggagctgctgcagaagtattctgtgctcttctcagagcctctg
tgctatggaggcaagaaaagaatgataaacagcaggaagacccagaagaagaggagtttg
actacaggtgacgttggtacatgtgcaaatcctgtagaaatggcagaaagccaagttttg
gaactgagagagaggctggagatggacctcacccacctaggagaggaacactatgatggg
attcgaagaaagaaagagcagcacgccacagagcaagtgaccaagattatagagctggcc
agagagaagcaggcaactgagctgaaggcactgaaggagtcattggaaagtaacattaaa
gacattaagaagaagctggaggcaaagagagtggaccgaatccaggctgtgatgaggagc
accagcaacaaggcagctcaggagaggttgaagaaagaaattaacaactctcacattcag
gaggtggtgcaaaccatcaaactggtaacagaaaagacagacaggtatcagcagaaactg
gaagagaagcaggcagagaatctgagagcaatcaaggagaaagaaagccagctccagcag
gaagcactggtggagtatgaggagaagttgaaaagactgagtatggaagtgcaggagatg
gtgaagaactatgcaagaggaagctttcctggagagccagaggctcagaaggatgcagtt
cagagcattcctgagggagaacaaggccctacagaccaactggaagaaaagatcctggtg
gcagaggtgtcaaggctcacattcaccgtgcctggaccgccaggagccgaaacagacgtc
gagatcgaagaaagcatattttga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (9)   
   Pfam (9)   
All databases (19)   

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