KEGG   Delphinus delphis (saddleback dolphin): 132432049
Entry
132432049         CDS       T11117                                 
Symbol
MAPK13
Name
(RefSeq) mitogen-activated protein kinase 13 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
ddp  Delphinus delphis (saddleback dolphin)
Pathway
ddp01522  Endocrine resistance
ddp04010  MAPK signaling pathway
ddp04015  Rap1 signaling pathway
ddp04068  FoxO signaling pathway
ddp04071  Sphingolipid signaling pathway
ddp04114  Oocyte meiosis
ddp04148  Efferocytosis
ddp04218  Cellular senescence
ddp04261  Adrenergic signaling in cardiomyocytes
ddp04370  VEGF signaling pathway
ddp04380  Osteoclast differentiation
ddp04517  IgSF CAM signaling
ddp04519  Cadherin signaling
ddp04550  Signaling pathways regulating pluripotency of stem cells
ddp04611  Platelet activation
ddp04613  Neutrophil extracellular trap formation
ddp04620  Toll-like receptor signaling pathway
ddp04621  NOD-like receptor signaling pathway
ddp04622  RIG-I-like receptor signaling pathway
ddp04625  C-type lectin receptor signaling pathway
ddp04657  IL-17 signaling pathway
ddp04658  Th1 and Th2 cell differentiation
ddp04659  Th17 cell differentiation
ddp04660  T cell receptor signaling pathway
ddp04664  Fc epsilon RI signaling pathway
ddp04668  TNF signaling pathway
ddp04670  Leukocyte transendothelial migration
ddp04714  Thermogenesis
ddp04722  Neurotrophin signaling pathway
ddp04723  Retrograde endocannabinoid signaling
ddp04728  Dopaminergic synapse
ddp04750  Inflammatory mediator regulation of TRP channels
ddp04912  GnRH signaling pathway
ddp04914  Progesterone-mediated oocyte maturation
ddp04917  Prolactin signaling pathway
ddp04926  Relaxin signaling pathway
ddp04932  Non-alcoholic fatty liver disease
ddp04933  AGE-RAGE signaling pathway in diabetic complications
ddp04935  Growth hormone synthesis, secretion and action
ddp04936  Alcoholic liver disease
ddp05014  Amyotrophic lateral sclerosis
ddp05020  Prion disease
ddp05022  Pathways of neurodegeneration - multiple diseases
ddp05132  Salmonella infection
ddp05133  Pertussis
ddp05135  Yersinia infection
ddp05140  Leishmaniasis
ddp05142  Chagas disease
ddp05145  Toxoplasmosis
ddp05152  Tuberculosis
ddp05161  Hepatitis B
ddp05163  Human cytomegalovirus infection
ddp05167  Kaposi sarcoma-associated herpesvirus infection
ddp05169  Epstein-Barr virus infection
ddp05170  Human immunodeficiency virus 1 infection
ddp05171  Coronavirus disease
ddp05205  Proteoglycans in cancer
ddp05208  Chemical carcinogenesis - reactive oxygen species
ddp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ddp05415  Diabetic cardiomyopathy
ddp05417  Lipid and atherosclerosis
ddp05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ddp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    132432049 (MAPK13)
   04015 Rap1 signaling pathway
    132432049 (MAPK13)
   04370 VEGF signaling pathway
    132432049 (MAPK13)
   04668 TNF signaling pathway
    132432049 (MAPK13)
   04068 FoxO signaling pathway
    132432049 (MAPK13)
   04071 Sphingolipid signaling pathway
    132432049 (MAPK13)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    132432049 (MAPK13)
   04519 Cadherin signaling
    132432049 (MAPK13)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    132432049 (MAPK13)
  09143 Cell growth and death
   04114 Oocyte meiosis
    132432049 (MAPK13)
   04218 Cellular senescence
    132432049 (MAPK13)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    132432049 (MAPK13)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    132432049 (MAPK13)
   04613 Neutrophil extracellular trap formation
    132432049 (MAPK13)
   04620 Toll-like receptor signaling pathway
    132432049 (MAPK13)
   04621 NOD-like receptor signaling pathway
    132432049 (MAPK13)
   04622 RIG-I-like receptor signaling pathway
    132432049 (MAPK13)
   04625 C-type lectin receptor signaling pathway
    132432049 (MAPK13)
   04660 T cell receptor signaling pathway
    132432049 (MAPK13)
   04658 Th1 and Th2 cell differentiation
    132432049 (MAPK13)
   04659 Th17 cell differentiation
    132432049 (MAPK13)
   04657 IL-17 signaling pathway
    132432049 (MAPK13)
   04664 Fc epsilon RI signaling pathway
    132432049 (MAPK13)
   04670 Leukocyte transendothelial migration
    132432049 (MAPK13)
  09152 Endocrine system
   04912 GnRH signaling pathway
    132432049 (MAPK13)
   04914 Progesterone-mediated oocyte maturation
    132432049 (MAPK13)
   04917 Prolactin signaling pathway
    132432049 (MAPK13)
   04926 Relaxin signaling pathway
    132432049 (MAPK13)
   04935 Growth hormone synthesis, secretion and action
    132432049 (MAPK13)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    132432049 (MAPK13)
  09156 Nervous system
   04728 Dopaminergic synapse
    132432049 (MAPK13)
   04723 Retrograde endocannabinoid signaling
    132432049 (MAPK13)
   04722 Neurotrophin signaling pathway
    132432049 (MAPK13)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    132432049 (MAPK13)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    132432049 (MAPK13)
  09159 Environmental adaptation
   04714 Thermogenesis
    132432049 (MAPK13)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    132432049 (MAPK13)
   05208 Chemical carcinogenesis - reactive oxygen species
    132432049 (MAPK13)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    132432049 (MAPK13)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    132432049 (MAPK13)
   05161 Hepatitis B
    132432049 (MAPK13)
   05171 Coronavirus disease
    132432049 (MAPK13)
   05163 Human cytomegalovirus infection
    132432049 (MAPK13)
   05167 Kaposi sarcoma-associated herpesvirus infection
    132432049 (MAPK13)
   05169 Epstein-Barr virus infection
    132432049 (MAPK13)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    132432049 (MAPK13)
   05135 Yersinia infection
    132432049 (MAPK13)
   05133 Pertussis
    132432049 (MAPK13)
   05152 Tuberculosis
    132432049 (MAPK13)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    132432049 (MAPK13)
   05140 Leishmaniasis
    132432049 (MAPK13)
   05142 Chagas disease
    132432049 (MAPK13)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    132432049 (MAPK13)
   05020 Prion disease
    132432049 (MAPK13)
   05022 Pathways of neurodegeneration - multiple diseases
    132432049 (MAPK13)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    132432049 (MAPK13)
   05418 Fluid shear stress and atherosclerosis
    132432049 (MAPK13)
   05415 Diabetic cardiomyopathy
    132432049 (MAPK13)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    132432049 (MAPK13)
   04932 Non-alcoholic fatty liver disease
    132432049 (MAPK13)
   04933 AGE-RAGE signaling pathway in diabetic complications
    132432049 (MAPK13)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    132432049 (MAPK13)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ddp01001]
    132432049 (MAPK13)
Enzymes [BR:ddp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     132432049 (MAPK13)
Protein kinases [BR:ddp01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   132432049 (MAPK13)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 RIO1 APH
Other DBs
NCBI-GeneID: 132432049
NCBI-ProteinID: XP_059877903
Position
10:complement(38389351..38401524)
AA seq 372 aa
MNFTWKKGFYKQDVNKTAWELPKTYVSLTHVGSGAYGAVCSAIEKQSGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFYLVMPFMQMDLQKIMGM
EFGEDKIQYLVYQMLKGLKYIHSAGVIHRDLKPGNLAVNEDCELKILDFGLARQADAEMT
GYVVTRWYRAPEVILRWRHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPDAEFVQKLNDKACFSVFQAKSYIQSLPQTPKKDFSQLFQHASPQAADLLEKMLELDMD
KRLTASQALTHPFFESCRDPEEETEAQQPFDDFLEQEKLTVDEWKHHIYKEIVNFSPIAR
KDSRRRSGMKLQ
NT seq 1119 nt   +upstreamnt  +downstreamnt
atgaacttcacctggaaaaagggcttctacaagcaggacgtcaacaagaccgcctgggag
ctgcccaagacctacgtgtccctgacgcacgtaggcagcggggcctacggcgccgtgtgc
tcagccatcgagaagcagtcaggggagaaggtggccatcaagaaactgagccggcccttc
cagtctgagatctttgccaagcgggcctatcgcgagctgctgctgctgaagcacatgcag
catgagaacgtcatcggactcctggatgtcttcaccccagcctcttccctgcgcaacttt
catgatttctacctggtgatgcccttcatgcaaatggacctgcagaagatcatgggaatg
gagttcggtgaggacaagatccagtacctggtgtatcagatgctcaaaggtcttaagtac
atccactcagctggggtcatccacagggacctgaagccaggcaaccttgctgtcaatgag
gattgtgagctgaagattttggattttgggttggcacggcaagcagatgcagagatgacc
ggctatgtggtgacccgctggtaccgggcccctgaggtgatcctccgctggaggcactac
aaccagactgtggacatctggtctgtgggctgtatcatggcggagatgctgacggggaaa
actctgttcaaggggaaagattacctggaccagctgacgcagatcctgaaagtgacgggg
gtgccggacgctgagtttgtgcagaagttgaatgacaaagcgtgcttttctgtcttccag
gccaaatcctacatccagtccctgccacaaacccccaagaaggatttctctcagctcttc
cagcatgccagcccccaggctgcagacctgctggagaagatgctggagctggacatggac
aagcgcctgaccgcctctcaggccctcacccaccccttctttgaatcctgccgggaccct
gaggaggaaacagaggcccagcagccatttgatgatttcttagaacaggagaaactcaca
gtggatgaatggaagcaccacatttacaaggagattgtgaacttcagccccatcgcccgg
aaggactctcggcgccggagtggcatgaagctgcagtga

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