KEGG   Delphinapterus leucas (beluga whale): 111186361
Entry
111186361         CDS       T05885                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle01522  Endocrine resistance
dle04010  MAPK signaling pathway
dle04015  Rap1 signaling pathway
dle04068  FoxO signaling pathway
dle04071  Sphingolipid signaling pathway
dle04114  Oocyte meiosis
dle04148  Efferocytosis
dle04218  Cellular senescence
dle04261  Adrenergic signaling in cardiomyocytes
dle04370  VEGF signaling pathway
dle04380  Osteoclast differentiation
dle04517  IgSF CAM signaling
dle04519  Cadherin signaling
dle04550  Signaling pathways regulating pluripotency of stem cells
dle04611  Platelet activation
dle04613  Neutrophil extracellular trap formation
dle04620  Toll-like receptor signaling pathway
dle04621  NOD-like receptor signaling pathway
dle04622  RIG-I-like receptor signaling pathway
dle04625  C-type lectin receptor signaling pathway
dle04657  IL-17 signaling pathway
dle04658  Th1 and Th2 cell differentiation
dle04659  Th17 cell differentiation
dle04660  T cell receptor signaling pathway
dle04664  Fc epsilon RI signaling pathway
dle04668  TNF signaling pathway
dle04670  Leukocyte transendothelial migration
dle04714  Thermogenesis
dle04722  Neurotrophin signaling pathway
dle04723  Retrograde endocannabinoid signaling
dle04728  Dopaminergic synapse
dle04750  Inflammatory mediator regulation of TRP channels
dle04912  GnRH signaling pathway
dle04914  Progesterone-mediated oocyte maturation
dle04917  Prolactin signaling pathway
dle04926  Relaxin signaling pathway
dle04932  Non-alcoholic fatty liver disease
dle04933  AGE-RAGE signaling pathway in diabetic complications
dle04935  Growth hormone synthesis, secretion and action
dle04936  Alcoholic liver disease
dle05014  Amyotrophic lateral sclerosis
dle05020  Prion disease
dle05022  Pathways of neurodegeneration - multiple diseases
dle05132  Salmonella infection
dle05133  Pertussis
dle05135  Yersinia infection
dle05140  Leishmaniasis
dle05142  Chagas disease
dle05145  Toxoplasmosis
dle05152  Tuberculosis
dle05161  Hepatitis B
dle05163  Human cytomegalovirus infection
dle05167  Kaposi sarcoma-associated herpesvirus infection
dle05169  Epstein-Barr virus infection
dle05170  Human immunodeficiency virus 1 infection
dle05171  Coronavirus disease
dle05205  Proteoglycans in cancer
dle05208  Chemical carcinogenesis - reactive oxygen species
dle05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
dle05415  Diabetic cardiomyopathy
dle05417  Lipid and atherosclerosis
dle05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:dle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111186361 (MAPK12)
   04015 Rap1 signaling pathway
    111186361 (MAPK12)
   04370 VEGF signaling pathway
    111186361 (MAPK12)
   04668 TNF signaling pathway
    111186361 (MAPK12)
   04068 FoxO signaling pathway
    111186361 (MAPK12)
   04071 Sphingolipid signaling pathway
    111186361 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    111186361 (MAPK12)
   04519 Cadherin signaling
    111186361 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    111186361 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    111186361 (MAPK12)
   04218 Cellular senescence
    111186361 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    111186361 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    111186361 (MAPK12)
   04613 Neutrophil extracellular trap formation
    111186361 (MAPK12)
   04620 Toll-like receptor signaling pathway
    111186361 (MAPK12)
   04621 NOD-like receptor signaling pathway
    111186361 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    111186361 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    111186361 (MAPK12)
   04660 T cell receptor signaling pathway
    111186361 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    111186361 (MAPK12)
   04659 Th17 cell differentiation
    111186361 (MAPK12)
   04657 IL-17 signaling pathway
    111186361 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    111186361 (MAPK12)
   04670 Leukocyte transendothelial migration
    111186361 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    111186361 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    111186361 (MAPK12)
   04917 Prolactin signaling pathway
    111186361 (MAPK12)
   04926 Relaxin signaling pathway
    111186361 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    111186361 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    111186361 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    111186361 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    111186361 (MAPK12)
   04722 Neurotrophin signaling pathway
    111186361 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    111186361 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    111186361 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    111186361 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    111186361 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    111186361 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    111186361 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    111186361 (MAPK12)
   05161 Hepatitis B
    111186361 (MAPK12)
   05171 Coronavirus disease
    111186361 (MAPK12)
   05163 Human cytomegalovirus infection
    111186361 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    111186361 (MAPK12)
   05169 Epstein-Barr virus infection
    111186361 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    111186361 (MAPK12)
   05135 Yersinia infection
    111186361 (MAPK12)
   05133 Pertussis
    111186361 (MAPK12)
   05152 Tuberculosis
    111186361 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    111186361 (MAPK12)
   05140 Leishmaniasis
    111186361 (MAPK12)
   05142 Chagas disease
    111186361 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    111186361 (MAPK12)
   05020 Prion disease
    111186361 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    111186361 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    111186361 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    111186361 (MAPK12)
   05415 Diabetic cardiomyopathy
    111186361 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    111186361 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    111186361 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    111186361 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    111186361 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dle01001]
    111186361 (MAPK12)
Enzymes [BR:dle01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     111186361 (MAPK12)
Protein kinases [BR:dle01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   111186361 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Kinase-like Haspin_kinase
Other DBs
NCBI-GeneID: 111186361
NCBI-ProteinID: XP_022452591
UniProt: A0A2Y9Q525
Position
Unknown
AA seq 456 aa
MSSPPPARKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPNETLDDFTDFYLVMPFMGTDLGKLM
KHEKLSEDRIQFLVYQMLKGLKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGETLFKGSDRILYLELGAG
EACPTPGAGCGGGLPYTCGEQARRTARAGWVGELCPTPGAGCGGGLPYTCGEQARRTARA
GWVGELCPLAPRCAPDLSQDLDQLKEIMKVTGTPPAEFVQRLQSAEAQNYMNGLPELEKK
DFAAILTNASPLAVNLLEKMLVLDAERRVTAAKALTHPYFESLHDTEDEPKAQKYDESFD
DVDRTLEEWKRVTYREVLSFKPPRQLGTKVSKETAL
NT seq 1371 nt   +upstreamnt  +downstreamnt
atgagctctccgccgcccgcccgcaagggcttttaccgccaggaggtgaccaagacggcc
tgggaggtgcgcgccgtgtaccaggacctgcagcccgtaggctcgggcgcctatggcgcc
gtgtgctcggcggtggacagccgcacgggcgccaaggtggccataaagaagctgtaccgg
cccttccagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctgctcaagcac
atgcgccatgagaacgtaattgggctgctggatgtgttcacacccaatgagaccctggat
gatttcacagacttttacctggtgatgccgttcatgggcaccgacctggggaagctcatg
aagcacgagaagctgagtgaggaccgaatccagttcctcgtctaccagatgctcaagggg
ctgaagtacatccatgctgctggcatcatccacagggacctgaagcccggcaacctggcc
gtgaacgaggactgtgagctcaagatcctggactttggcctggcccggcaggcagatagc
gagatgactgggtacgtggtgacccggtggtaccgggcgcctgaggtcatcttgaattgg
atgcactacacacagacggtggacatctggtcagtgggctgcatcatggctgagatgatc
acaggggagacgctcttcaaaggcagcgaccgtatcctatacctggagctgggtgcgggg
gaggcttgccctacacctggagctgggtgcgggggaggcttgccctacacctgcggggag
caggccaggcgcactgcccgggctgggtgggtaggtgagctctgccctacacctggagct
gggtgcgggggaggcttgccctacacctgcggggagcaggccaggcgcactgcgcgggct
gggtgggtaggtgagctctgccctctggccccgcgctgtgctcctgacctcagccaagac
ctggaccagctgaaggaaatcatgaaggtgacggggacgcctcccgccgagttcgtgcag
aggctgcagagtgccgaggctcagaactacatgaatggcctccccgagctagagaaaaag
gattttgccgccatcctgaccaacgcaagccctctggctgtgaacctcctggagaagatg
ctcgtgctggatgcggagcggcgggtgacggcggccaaggcgctgacccacccctacttc
gagtcgctgcacgacacggaggacgagcccaaagctcaaaagtacgatgaatcctttgat
gacgtggaccgcacgctggaagagtggaagcgtgtcacatacagagaggtgctcagcttc
aagcctccccgacagctggggaccaaggtctccaaggagacggccctgtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (7)   
   Pfam (7)   
All databases (20)   

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