KEGG   Drosophila melanogaster (fruit fly): Dmel_CG4574
Entry
Dmel_CG4574       CDS       T00030                                 
Symbol
Plc21C
Name
(RefSeq) phospholipase C at 21C, isoform D
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme00562  Inositol phosphate metabolism
dme01100  Metabolic pathways
dme04070  Phosphatidylinositol signaling system
dme04081  Hormone signaling
dme04082  Neuroactive ligand signaling
dme04310  Wnt signaling pathway
dme04745  Phototransduction - fly
Module
dme_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:dme00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    Dmel_CG4574 (Plc21C)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    Dmel_CG4574 (Plc21C)
   04070 Phosphatidylinositol signaling system
    Dmel_CG4574 (Plc21C)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    Dmel_CG4574 (Plc21C)
   04081 Hormone signaling
    Dmel_CG4574 (Plc21C)
 09150 Organismal Systems
  09157 Sensory system
   04745 Phototransduction - fly
    Dmel_CG4574 (Plc21C)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dme04131]
    Dmel_CG4574 (Plc21C)
Enzymes [BR:dme01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     Dmel_CG4574 (Plc21C)
Membrane trafficking [BR:dme04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    Dmel_CG4574 (Plc21C)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    Dmel_CG4574 (Plc21C)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2 EF-hand_15 LVIVD PH_12 LvrA_C LPD39 N4_RNAP_helical
Other DBs
NCBI-GeneID: 33204
NCBI-ProteinID: NP_995605
FlyBase: FBgn0004611
UniProt: P25455
Position
2L
AA seq 1318 aa
MMSAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELD
ILDIATIRDVRTGQYAKRPKDNKLRQIVTLGPQDTLEEKTVTVCHGSDFVNMTFVNFCCT
RRDIAQLWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNK
EDRKRVEKALDVTGLPSGKVDSISVSKFQFEDFYNLYKYLTQRSEVERLFDSIVGNSKRK
CMSIAQLVEFLNKTQRDPRLNEILYPYANPARAKELIQQYEPNKFNAQKGQLSLDGFLRY
LMGDDNPIMAPSKLDLCDDMDQPMSHYFINSSHNTYLTGHQLTGKSSVEIYRQCLLAGCR
CVELDFWNGRTEEPVIVHGYTFVPEIFAKDVLEAIAESAFKTSEYPVILSFENHCNPRQQ
AKIANYCREIFGDMLLDKPLDSHPLEPNMDLPPPAMLRRKIIIKNKKKHHHHHHHHHHKK
PAQVGTPAANNKLTTANSVDAKAAQQVGLSASHEDGGVTRSTANGDVATGTGTGSAAGTA
GHAPPLQQIRQSSKDSTGSSDSDSSSEDESLPNTTPNLPSGNEPPPEKAQKETEAGAEIS
ALVNYVQPIHFSSFENAEKKNRCYEMSSFDEKQATTLLKERPIEFVNYNKHQLSRVYPAG
TRFDSSNFMPQLFWNAGCQLVALNFQTLDLAMQLNLGIFEYNARSGYLLKPEFMRRSDRR
LDPFAESTVDGIIAGTVSITVLSGQFLTDKRANTFVEVDMYGLPADTVRKKFRTKTVRDN
GMNPLYDEEPFVFKKVVLPELASIRIAAYEEGGKLIGHRVLPVIGLCPGYRHVNLRSEVG
QPIALASLFLCVVVKDYVPDDLSNFAEALANPIKYQSELEKRDIQLSVLTDEAEALGSAD
EDLSKSFVFVQVGGQKKELRPVESLATSPKHRPSISAAAAMSVDVTVDRTDGGRGEDSIS
IVAPSIQHQHSLDQSVSTSIRQVESSQFDVDLVLAEPLEKILDHKSVKEKRLEMEKKLES
LRKKHDKEKIKIAGQKSSPLEGKKPKFAITNKLVKRLSNKSLNCLSPHSEPGVEIPACPL
DLGDSSEESAAADAGEDLAGGSSSLDGRTQESRLRSACREYTSQYRELQEKYHEAIYSAA
EKVLKTSQTGQTKQLKASLDKVTGEVMHQLQEARRNEVKNLATVHRDRDELIRMKREVAS
SVVERGVAERVRLKQTFDRRTDELQKQHDSVRNALAEHRSKARQILDKEAESRSCVSSNG
FLVLFHGPHHHGCTGSGSSALSGNNLTLNLDAGAAGSHSAISPAKSHNSIAAAAEMKT
NT seq 3957 nt   +upstreamnt  +downstreamnt
atgatgagcgccggaggaacctacatctccaccgccagcgtggaggtgccacaagctctg
caagatggcgagaagttcattcgatgggatgatgactcgggcactggaacaccggttaca
atgcgcgtcgatgccaagggcttcttcctctactgggtcgaccagaacaacgagctggat
atccttgatatagccaccatacgcgacgttcgcacaggacagtacgctaagcgaccaaag
gacaacaagctgcgccagattgtgacgctgggcccccaggacacgctcgaggagaagaca
gtgacggtatgccacggctcggacttcgtcaacatgacgttcgtcaacttctgctgcacc
cggcgggacatagcccagctctggaccgacggactcatcaagttggcctacagcttggcc
cagctcaatggctcggcgattatgttcctgcagaaggcccataccaaactgtgtctccag
gtggacaaaagcggccgcataccagtgaaaaacatcataaaactttttgcccaaaacaag
gaggatcgcaaacgtgtcgagaaggcgctggacgtgaccggtttgccgtcgggaaaggtc
gatagcatatcggtgtccaaatttcaattcgaggacttttacaatttgtacaaatatctc
acgcagcgttcggaggtggaacgcctctttgacagcatcgttggcaactcgaagcgcaag
tgcatgtccatcgctcaactggtggagttcctgaacaagacacagcgtgatccccgcctg
aacgagatcctctacccttatgcgaatcccgcccgcgccaaggagctcatccagcaatat
gagcccaacaagttcaatgcgcaaaagggccaactcagcctggatggctttttgaggtac
ttaatgggcgacgacaatcccatcatggcgcccagcaagctcgatctctgcgatgacatg
gaccagccgatgtcgcactacttcatcaactcctcgcataacacctacttgacgggacac
cagctgaccggcaagtcgtccgtcgagatttacaggcagtgtctcctggcgggatgcaga
tgcgttgagctcgacttctggaacggacgcaccgaggagccagtcattgtccacggctat
acgttcgtgcccgagatatttgccaaggacgtgctggaggccatcgcagagagtgcattt
aaaacatccgaataccctgtgatattgagctttgagaatcactgcaaccctaggcaacag
gcgaaaattgccaactattgtcgcgaaatatttggcgatatgctgctcgataagcctctg
gactctcatccgctggagccgaacatggacttgccaccgccggcgatgctgcgccgcaag
attataatcaagaacaagaagaagcatcaccaccaccatcaccatcatcaccacaaaaag
ccagcgcaggtgggcacgccggcagccaacaacaaactgactacagcgaattcagtggat
gccaaggcggcgcaacaagtcggtttgtcggcctcgcatgaggatgggggcgtgaccagg
agcaccgccaacggtgacgttgccactggaacaggaaccggaagtgctgctgggacagca
ggacacgcgccgccgttgcaacaaatccgccaaagctccaaagacagcactggatcctcc
gattcggacagctcttcggaggatgaatccctgcctaacaccacgcccaatttgcccagc
ggcaacgaacctccgccagaaaaggctcaaaaggaaacggaggcgggagcagagatttca
gctttggtcaactatgttcagcccatccattttagctcttttgagaatgcggaaaaaaag
aatcgatgctacgaaatgtcttcgtttgatgaaaaacaggcgacaacattattgaaggag
cgaccgattgaatttgtgaactacaacaaacaccaattatctcgtgtctatccggcgggc
actcgctttgatagctccaactttatgccgcagttgttctggaatgccggatgtcagctc
gtggcacttaacttccaaaccctcgatctggccatgcaactcaacttggggatctttgag
tataacgctcggtccggttatctacttaagccggagtttatgcgccgatcagatcgcaga
ttggatcccttcgcggaaagcactgtggatggcatcatagcaggcacagtatcaatcacg
gttctatctggtcagtttctcacggataagagggcgaacacttttgtggaagttgatatg
tacggtttgccagcggacacggtgagaaagaagtttcgcaccaagacagtgcgggataat
ggaatgaatcccctttatgacgaggagccgttcgtgtttaagaaggtggttctccccgag
ttggcgagcattcgaattgcagcatatgaagagggtggcaaactcattggtcaccgcgtt
ttgcccgtaatcggtctttgccctggttaccgacatgtgaatctccgatctgaagtgggt
caaccaatagcccttgcctctcttttcctgtgcgtggtggtcaaggattatgtacccgat
gatctttccaatttcgcagaggcgctagctaaccctattaaataccaaagtgagctagag
aagcgcgatattcaactatctgttttgaccgacgaagccgaagcgctgggcagtgcggac
gaggatctctccaagtcgttcgttttcgtccaagtaggtggccaaaaaaaggagctgcgt
ccggttgaatcgcttgcgacttcgccgaagcataggccgagcatctcggccgccgcagca
atgagtgttgacgttaccgtggatcggaccgatggcggaaggggagaagatagcatctct
attgtagcaccctcaatacagcatcagcactctctagaccagtccgtaagcacctccatc
cgacaggtggagtcctcgcagtttgatgtcgatcttgtgttggcggagccgctggaaaag
atattggatcacaagtccgtcaaggaaaagcgtctcgagatggaaaagaagctggagtca
ctgcgaaagaagcatgacaaggaaaagattaagatcgccggccagaaatccagtccgcta
gagggcaagaagccgaagtttgccatcacgaataagctggtgaagcggctaagcaacaag
agtcttaattgtctttctccgcacagcgagcctggtgtagagatccccgcctgccctctg
gatctgggcgatagcagcgaggagagtgcagccgcggatgccggtgaggacttagccggt
gggagcagcagtctggatggcagaactcaagagtcgcgattacgcagtgcctgccgggag
tacacttcccagtaccgtgagctgcaggagaagtaccatgaggcaatttacagtgcagcc
gagaaggtgctgaagacatcgcaaactgggcaaacaaagcagttaaaagcatctctggac
aaggtcactggagaggttatgcaccagctgcaggaggcccgccgcaacgaggttaagaat
ctggccaccgtgcaccgggatcgtgatgagctgatcagaatgaaacgcgaggtggcaagc
tccgttgtggaacgtggcgtagctgaacgtgtgcggctgaagcagacctttgaccggaga
acggatgaacttcagaagcagcacgactcagtgcgcaatgccctggcagagcaccgctcc
aaggctcgtcaaattctcgacaaggaggcagaatcgcgaagctgtgtatccagcaatggc
ttcttggtcctcttccatggacctcatcaccatggctgtacgggctccggctcgtcagcc
ctttcaggcaataatctcactctaaatctggacgcgggggctgccggtagtcattcagcc
atttcgccggcaaagtcgcacaacagcatcgcagcagcggccgagatgaagacgtaa

  All links  
Gene (41)   
   RefGene (37)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   FLYBASE (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (12)   
   Pfam (12)   
All databases (67)   

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