KEGG   Dipodomys merriami (Merriam's kangaroo rat): 138817846
Entry
138817846         CDS       T11079                                 
Symbol
Apc2
Name
(RefSeq) adenomatous polyposis coli protein 2 isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
dmer  Dipodomys merriami (Merriam's kangaroo rat)
Pathway
dmer04310  Wnt signaling pathway
dmer04390  Hippo signaling pathway
dmer04519  Cadherin signaling
dmer04550  Signaling pathways regulating pluripotency of stem cells
dmer04810  Regulation of actin cytoskeleton
dmer04934  Cushing syndrome
dmer05010  Alzheimer disease
dmer05022  Pathways of neurodegeneration - multiple diseases
dmer05165  Human papillomavirus infection
dmer05200  Pathways in cancer
dmer05206  MicroRNAs in cancer
dmer05210  Colorectal cancer
dmer05213  Endometrial cancer
dmer05217  Basal cell carcinoma
dmer05224  Breast cancer
dmer05225  Hepatocellular carcinoma
dmer05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:dmer00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    138817846 (Apc2)
   04390 Hippo signaling pathway
    138817846 (Apc2)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    138817846 (Apc2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    138817846 (Apc2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    138817846 (Apc2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    138817846 (Apc2)
   05206 MicroRNAs in cancer
    138817846 (Apc2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    138817846 (Apc2)
   05225 Hepatocellular carcinoma
    138817846 (Apc2)
   05226 Gastric cancer
    138817846 (Apc2)
   05217 Basal cell carcinoma
    138817846 (Apc2)
   05213 Endometrial cancer
    138817846 (Apc2)
   05224 Breast cancer
    138817846 (Apc2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    138817846 (Apc2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    138817846 (Apc2)
   05022 Pathways of neurodegeneration - multiple diseases
    138817846 (Apc2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    138817846 (Apc2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:dmer01009]
    138817846 (Apc2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:dmer03036]
    138817846 (Apc2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:dmer04812]
    138817846 (Apc2)
Protein phosphatases and associated proteins [BR:dmer01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     138817846 (Apc2)
Chromosome and associated proteins [BR:dmer03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    138817846 (Apc2)
Cytoskeleton proteins [BR:dmer04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     138817846 (Apc2)
SSDB
Motif
Pfam: APC_basic APC_rep APC_N_CC APC_r Arm_APC_u3 Arm Suppressor_APC SAMP ARM_PUB ZER1-like_2nd SSNA1 PEA2_C bZIP_1 Sec7-like_HUS MPS2 PDC10_C CCDC138_cc Par-4_C HALZ Herpes_BLRF2
Other DBs
NCBI-GeneID: 138817846
NCBI-ProteinID: XP_069864683
Position
Unknown
AA seq 2317 aa
MGLLGLLSLLHSAFFGDQTLQELKMTSSVASYEQLVRQVEALKAENSHLRQELRDNSSHL
SKLETETSGMKEVLKHLQGKLEQEARVLVSSGQTEVLEQLKALQMDISSLYNLKFQPPAL
GPEPVARTPEESPVHGSGPSKDSFGELSRATIRLLEELDRERCFLLSEIEKEEKEKLWYY
SQLQGLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRA
SRLEQIDKELLEAQDRVQQTEPQALLAVKPVSVEEDPEAEVPTHPEDGTPQPGNSKVEVV
FWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGTEAGAGGRTGTPG
APGAKDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDSGPE
GSGTGCVPVPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQAVAELLQVDYEMHKMTRD
PLNLALRRYAGMTLTNLTFGDVANKAALCARRGCMEAMVAQLASESEELHQVVSSILRNL
SWRADMNSKKVLREVGSMTALMQCVLRASKESTLKSVLSALWNLSAHSTENKAAICQVDG
ALGFLVSTLTYRCQGNSLAVIESGGGILRNVSSLIATREDYRQVLRDHNCLQTLLQHLTS
HSLTIVSNACGTLWNLSARSPRDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLA
HRPAKYQAAATAVSPGTCMPSLYVRKQRALEAELDTRHLAQALGHLEKQGLPEPEPEATS
KKPLPPLRHLDGLAQDYASDSGCFDDDDAPSLAAATAEPASPAVLSLFLGSNFLQGQALA
RTPPTRLGGLEAEKEASGEAAVAAKAKAKLALAVARIDRLVEDISALHTSSDDSFSLSSG
DPGQEAPREGRAQSCSPCRGPEGGRRESSGRAHPLLRLKAAHASLSNDSLNSGSTSDGYC
PREHMRPCPLASLAEHREDPLRGQARPSRLDLDLSGSKMEPPAPDTAAVTDAHVRTIKLS
PTYQHVPLLDGTATVGTRPLAGLGASSGARKQAWMPADTLNKAPEKLAAAPLPVASKVLQ
KLVAQDGPLSLSRCSSLSSLSSTGQAGPSEGGHLDDSDSSLEGLEETGPGEVELDGAWRG
PGSTSLPVAIPAPRRGCSRGLGLEDATPSSSSENCVQETPLVLSRCSSVSSLGSFESPSI
ASSIPSDPCSGLGSGTVSPSELPDSPGQTMPPSRSKTPPAPAGQPETSQFSLQWESYVKR
FLDIADCRERCQPPCELDAGSVRFTVEKPDENFSCASSLSALALHELYVQQDVELRLQPP
ACPERTGGGGAGHRRREEAGGRLKGPVATGSRTRKAADKELELLRECLGAAVPAQLRKVA
SALVPGHRALPVPVYMLVPAPAQDDSGSDSAEGTPVNFSSAASLSDETLQGPPREQPSGL
ADRKKPTGRTAPARQAPGHRPKAGGAGKSTEQARGAARNRVALELPLSRPSSARSEKEAS
RQGKTRGDGALQSLCLTTPTEEAVYCFYDSDDEPPVTVPPPRRPSAIPRALKRDPTTGRK
EAQAPPQATPAVVPLTRAQPRLIVDETPPCYSLTSSASSLSEPEPSERPPSRPGGREPAV
TKDPGPGGGQDSSPSPRAEEELLRRCIGSAMPRRRPQTLASRRRKPRVARPNIRAAEMPR
ECREEVAGLDPASDLDSVEWQAIQEGANSIVTWLHQAAAAATMEASSESDSILSLVSGLS
NVSTLQPSKHRKGRPLGARAEGGGARRPEKRGTASAQSSDSPCSPGAVEKPRGSQKAASR
EPTVLRGRTVIYMPSSGPRTQPKGVPVPRTTLRKMGASGPTQPEVPAKTPSPGQQRSRSL
HRPGKISELAALRHAPRSATPPARLAKTPSSSSSQTSPASQPLPRKSPLATPSAGPLPGP
GASPVPKTPARALLAKQHKTQKSPVRIPFMQRPARRGPPPLARSAPEQSPRGRAGPEGSP
GARGGRLGLVRMASARSSGSESSDRSGFRRQLTFIKESPGLLRRRRSELSSVESAASASP
GASPRRGRPAGPALPAVFLCSSRCDELRASPRQSPAPQRPPGAAAAAALARPGPRAPRRT
SSESPSRLPVRAAAAPPPEAVKRYASLPHISVARRRDGGPAPAGPRRSSDGEARPLPRVS
APPPPPPPPGTTWRRIRDEDVPHILRSTLPASALPLRGASPEERKTSDAVVQTEELAAPK
TNSSTSPSLEAPPGVVPAAAPARAPAAPGPAKPPASAAPAHEGAGGFPASRHGSPSRAAR
VPPFNYVPSPMAAAAPAARDSAGEKPPAAAAPAGLLE
NT seq 6954 nt   +upstreamnt  +downstreamnt
atggggctcctggggcttctgagcctgctacactctgccttcttcggggaccagacactc
caggagctgaagatgacgagctcagtggcatcttacgagcaactggtgaggcaggtggag
gcactgaaagcggagaatagccatctgaggcaggagcttcgtgacaactcgagccacctg
tccaagctggagacagagacctcaggcatgaaggaagtgctaaagcatctacagggcaaa
ctggagcaggaggcccgcgtgctggtgtcctctgggcagacagaggtgctggagcagctg
aaagccctccagatggacatcagtagtctgtacaacctcaagtttcagccacccgccctt
ggcccggagcctgtcgcccggaccccagaggaaagtccagtccacggctctggaccctcc
aaagacagctttggagagttgagtcgggctaccatccggctgctggaggaactggaccgg
gagaggtgttttctgttgagtgaaattgagaaagaagagaaagagaagctctggtattat
tcacagttgcaaggcctgtccaagcgtctggatgagctgccccatgtagagacgcagttc
tcgatgcagatggacttgatccggcagcagctggagttcgaagctcagcacatccgctct
ctgatggaagagcgttttggcacctcagacgagatggtacaacgtgcgcagatccgagct
tcacgtctggagcagattgacaaagagctgcttgaggcgcaggaccgggtgcagcagacc
gagccccaggccctgctggcagtgaagccggtttcagtggaggaggacccagaggcagaa
gtccccacgcaccctgaggatggaacccctcagcctggcaacagcaaggtggaagtggtc
ttctggctgctgtccatgttggccacccgtgaccaggaagacactgcacgtaccttactg
gccatgtccagctcgcctgaaagctgcgtggctatgcgtcgatcaggctgccttccgctg
ctgcttcagattctccatggcactgaggcaggcgcaggaggtcgcacggggacaccaggg
gctccaggagcgaaggatgcccgcatgcgtgccaacgcagccctgcacaacatcgtcttc
tcacagcctgaccaaggcctagcacgcaaggagatgcgtgtcctacacgtgctggagcag
atccgggcctactgtgagacctgctgggactggcttcaggcccgggacagtgggcctgag
ggaagcggcactggctgtgtccctgtccccattgagcctcagatttgccaggccacctgt
gctgtgatgaaactgtcctttgatgaggaataccggcgtgctatgaatgagctaggtggg
ctgcaggccgtggcagagctacttcaggtagactacgagatgcacaagatgacccgagac
ccacttaacctcgccctacgccgctacgctggcatgaccctcaccaacctcacctttgga
gatgttgccaacaaggctgcactgtgtgctcgtcggggctgcatggaggccatggtggcc
cagctggcctctgagagtgaggagctgcaccaggtggtatccagcatcctccgaaatcta
tcatggagggcagacatgaacagcaagaaggtgctgagagaggtcggaagcatgacggcc
ctgatgcagtgtgtcctgagggcctccaaggagtccaccctgaagagcgtgctgagtgcc
ttgtggaacctgtcggcccacagcacggagaacaaggcagccatctgccaggtagacggt
gccctgggcttcctggtgagcacactgacctaccgctgccagggcaactccctggcagtc
atcgagagtggagggggcatcctgcgcaatgtatccagtctcatcgccacccgtgaagac
tacaggcaggtactccgagaccacaactgcctgcagacgctgctacagcacctgacctca
cacagcctgaccatcgtgagcaacgcctgcggcaccctgtggaacctttctgcccgcagc
ccccgggatcaggagctgctgtgggacctgggggctgtgggcatgctccgcaacctggta
cactccaagcacaagatgatcgccatgggcagtgcagctgccctgcgcaacctgctggcc
catcggcctgccaagtaccaggcggcagccacagctgtctccccgggtacgtgcatgccc
agtctgtacgtgaggaagcagcgagcactagaggctgagctggacacccgacatttggca
caggcacttggccacctggagaaacagggcctacctgagcctgagccggaagccacctct
aaaaagccgcttccgcccctgcgccacctggatgggctggcccaggactatgcctcggac
tcgggctgcttcgatgacgatgatgcaccatcgctggccgccgccacggcagaacctgcc
agccctgcggtgctgtctttgtttctgggtagcaacttcctgcagggccaggcactggct
cggaccccacccacccgtcttggtggcctggaagctgagaaggaggctagcggggaggca
gccgtggcagccaaggccaaagccaagctggcactggcggtggcacgaattgaccgtttg
gtggaggacatctctgccctacacacctcatcggatgacagcttcagcctcagctcaggg
gatcctggacaagaagcaccaagggaaggccgagcccagtcctgttctccatgccggggc
cctgagggtgggcggcgggagtccagtggccgggcccaccctctgctgaggctgaaggcg
gcccatgccagcctctccaatgacagcctcaacagcggcagcaccagtgatggatactgc
ccaagggagcacatgcggccctgcccgctcgcctcactggccgaacaccgcgaggaccca
ctgcgcggccaggcacgacccagccggctggacctggacctgtctggcagcaagatggag
ccacctgccccggacaccgcggctgtcacggatgcccatgtgcgcaccatcaagctgtca
cccacctaccagcacgtgccactgcttgatggcactgccactgtgggcacacggcccctt
gctggccttggagcctcctcaggggcccggaaacaggcctggatgcctgcagacactctg
aacaaggcacccgagaagctggcggctgccccgctgcctgtggccagcaaggtccttcag
aagttggtggcccaggatgggccactgtccctctcccgctgtagctctctgtcctcactg
tcctccactggccaagctggccccagtgagggtggccacttggatgacagtgactcttca
ctggaggggctggaggagactggccctggagaggtggaactggatggggcatggagaggt
cccggttccacctcactgccagtggccatccccgcaccccgtcggggctgcagccggggc
cttggcctggaggatgccacaccatccagttcgtcggaaaactgtgtgcaagagacacct
ctggtgctgagccgctgcagctcggtaagctcgctgggcagtttcgagagtccatccatt
gccagctccattcccagtgacccatgcagcgggctgggcagtggcacggtcagccccagc
gagctgcctgacagtcctgggcagaccatgccgcccagtcgcagcaagacaccgccagcc
ccagcaggccagcctgagaccagccagttcagcctgcagtgggagagctacgtgaagcgt
ttcctggacatagctgactgccgcgagcgctgccagccgccgtgcgagctggacgcaggc
agcgtgcgcttcactgtggagaagccggatgagaacttctcctgcgcctccagcctcagt
gcgctggccctgcacgagctctacgtgcagcaggatgtggagctgcgcctgcagccaccc
gcgtgcccagagcgcacagggggcgggggggcggggcaccgccgtcgggaggaggctggg
ggccgcctcaaaggtcctgtggccactggctctcgtacccgcaaggccgcagacaaggaa
ctggagctgctgcgtgaatgcttgggggccgctgtgcccgctcaactccgaaaggtggcc
tcggcactggtgcctggccaccgggctctgcctgtacccgtctacatgctggtacctgcc
cccgcccaggacgactcgggcagtgactcggccgagggcacacccgtcaacttctcgagt
gctgcctcgctcagtgatgagacgctgcagggacccccccgggagcagcccagtgggctg
gcagacaggaaaaaacccacaggccgcacagcccctgccaggcaggcccccggacaccgg
ccgaaggcagggggtgctggcaagagcacagagcaggcccggggggctgcgcggaaccgg
gtagcgctggagctgccccttagccgtccctcgagcgcgcgctcggagaaggaggcctca
cgccagggcaagacccgtggggacggggcgctgcagtcactgtgtctcaccacccccacc
gaggaggccgtgtactgcttctacgactctgatgacgagcccccagtcacagtgccaccg
ccacggcggccatccgccattcccagggccctgaagcgagatccaaccacaggcagaaag
gaggcccaggcccctccccaggccaccccagcggtggtgccactcaccagggctcagccc
aggctcattgtggacgagactccaccgtgctactccttgacctcctcggccagctccctc
agcgagccggagccatccgaacggccaccaagccgtccaggaggccgggagccagcggtc
accaaggatccaggcccaggtggcggacaggacagctctcctagcccacgggcagaagag
gagctactgcggagatgcattggctcagccatgcctaggcggcggccccagacactggca
tccaggcgtcgcaagccccgagttgccaggccgaacataagggcggcagagatgccccgg
gagtgccgtgaagaggtagcgggcctggatccagcttctgacctggacagtgttgagtgg
caagctatccaggagggtgccaactctatcgtcacctggttacaccaggcagcggcggca
gccaccatggaggcctcttcggagtcagactcgatcctgtctctggtgtcagggctgtcc
aatgtctccactctgcagccctccaagcacagaaagggacggccactgggggctcgagcc
gagggaggcggtgcccggcggccagagaaacggggcacagcctcagcccaaagtagtgac
agtccctgctcacctggagctgttgagaagccacgtggctctcagaaagcagcatccaga
gagcctaccgtgctgcggggccggacagtgatctacatgcccagttcaggtccccggacc
cagcccaaaggtgtccctgtgccccgcaccacactgagaaagatgggggcttctggtccc
acacagccagaagttccagccaagactcccagccctgggcagcagcgatctcgaagcctg
caccgaccgggcaagatctcagagttggcagccctgcgccatgcccccaggagtgctaca
ccccctgcccgcctggccaagaccccatcctccagttcctcccagacttctcctgcctcc
cagcccctgcctaggaagtcccccctggccaccccatcggccggtcccctgcccggcccg
ggagcctccccagtgcccaagacaccggctcgggctctcctggccaagcagcacaagaca
cagaagtcacctgtgcggatcccgttcatgcagaggcctgccaggcgaggtccaccgcca
ctggccaggtcggccccagagcagagccccaggggccgagcagggcccgaggggagcccc
ggggcccgtgggggtcgcctgggcctggtccgcatggcctcggcccgctccagcggcagc
gagtcctccgatcgctcgggcttccggcggcagctgaccttcatcaaggagtcgccaggc
ctgctgcgccgccgccgctccgagctgtcctccgtggagtccgcggcctcggcctccccg
ggcgcctcgccgcgccgcggccggcccgcggggcccgcgctccccgccgtcttcctctgc
tcctcccgctgcgacgagctccgggcgtccccgcgacagtccccggctccccagcggccc
cccggggcagcggcggcggcggccctggcccggccgggcccgcgggcgccccggcgcacc
agctccgagagcccgtcccgcctgccggtacgcgcggccgccgcgccgccgcccgaggcc
gtcaagcgctacgcctcgctgccgcacatcagcgtggcccggcggcgggacggcggcccc
gcgcccgcgggcccgcgccggagcagcgacggggaggcccggccgctgcccagggtgtcc
gcgccgccgccgccgccgccgccgccgggcaccacgtggaggcgcatccgcgacgaggac
gtcccgcacatcctgcgcagcacgctgcccgcctccgccctgccgctgcgcggcgcctcc
cccgaggagcgcaagaccagcgacgccgtggtccagaccgaggagctggcggcccccaag
accaactccagcacgtcccccagcctggaggcgccgcccggcgttgtcccggccgcggcc
ccggcccgcgcccccgccgcgccgggccccgccaagccgcccgcctccgccgccccggcc
cacgagggcgcgggcggcttccccgccagccggcacggctcccccagccgcgccgcccgc
gtcccccccttcaactacgtgcccagccccatggccgccgccgccccggccgcccgcgac
tccgccggggagaagcccccggccgccgcggcccccgccggcctcctggaatag

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (20)   
   Pfam (20)   
All databases (30)   

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