KEGG   Dipodomys ordii (Ord's kangaroo rat): 105986227
Entry
105986227         CDS       T07834                                 
Symbol
Pten
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
dord  Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord00562  Inositol phosphate metabolism
dord01100  Metabolic pathways
dord01521  EGFR tyrosine kinase inhibitor resistance
dord04068  FoxO signaling pathway
dord04070  Phosphatidylinositol signaling system
dord04071  Sphingolipid signaling pathway
dord04115  p53 signaling pathway
dord04140  Autophagy - animal
dord04150  mTOR signaling pathway
dord04151  PI3K-Akt signaling pathway
dord04218  Cellular senescence
dord04510  Focal adhesion
dord04931  Insulin resistance
dord05165  Human papillomavirus infection
dord05166  Human T-cell leukemia virus 1 infection
dord05200  Pathways in cancer
dord05206  MicroRNAs in cancer
dord05208  Chemical carcinogenesis - reactive oxygen species
dord05213  Endometrial cancer
dord05214  Glioma
dord05215  Prostate cancer
dord05218  Melanoma
dord05222  Small cell lung cancer
dord05224  Breast cancer
dord05225  Hepatocellular carcinoma
dord05230  Central carbon metabolism in cancer
dord05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
dord05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:dord00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    105986227 (Pten)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    105986227 (Pten)
   04070 Phosphatidylinositol signaling system
    105986227 (Pten)
   04071 Sphingolipid signaling pathway
    105986227 (Pten)
   04151 PI3K-Akt signaling pathway
    105986227 (Pten)
   04150 mTOR signaling pathway
    105986227 (Pten)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105986227 (Pten)
  09143 Cell growth and death
   04115 p53 signaling pathway
    105986227 (Pten)
   04218 Cellular senescence
    105986227 (Pten)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105986227 (Pten)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105986227 (Pten)
   05206 MicroRNAs in cancer
    105986227 (Pten)
   05208 Chemical carcinogenesis - reactive oxygen species
    105986227 (Pten)
   05230 Central carbon metabolism in cancer
    105986227 (Pten)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105986227 (Pten)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    105986227 (Pten)
   05214 Glioma
    105986227 (Pten)
   05218 Melanoma
    105986227 (Pten)
   05215 Prostate cancer
    105986227 (Pten)
   05213 Endometrial cancer
    105986227 (Pten)
   05224 Breast cancer
    105986227 (Pten)
   05222 Small cell lung cancer
    105986227 (Pten)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105986227 (Pten)
   05165 Human papillomavirus infection
    105986227 (Pten)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    105986227 (Pten)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    105986227 (Pten)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105986227 (Pten)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:dord01009]
    105986227 (Pten)
Enzymes [BR:dord01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     105986227 (Pten)
    3.1.3.48  protein-tyrosine-phosphatase
     105986227 (Pten)
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     105986227 (Pten)
Protein phosphatases and associated proteins [BR:dord01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    105986227 (Pten)
SSDB
Motif
Pfam: PTEN_C2 Tc-R-P DSPc PTP-SAK PTP-NADK Y_phosphatase Y_phosphatase3 PTPlike_phytase HHLA1_N
Other DBs
NCBI-GeneID: 105986227
NCBI-ProteinID: XP_012872498
UniProt: A0A1S3F766
Position
Unknown
AA seq 619 aa
GEAAAAAAAAAAAAPAPGRGSEPPVTISRAGDAGELVSPLLLPPTRRRRRRRIPGPGPVL
NLPSAAAALPLARAPEAAGGGSRSEDYSSSAHSAAAAARPLAAEEKQASSLQPSSSSSSS
GSSSSSGSSSSSSRRRSSHYPAAVQSQAAAERGASATAKSRAISILQKKPRHQQLLPSLS
SFFFSHRLPDMTAIIKEIVSRNKRRYQEDGFDLDLTCIHFCWLADPLCSFCHSSNLVICP
KVNAAYLDHLVWYFSDDLTSVFFKLLSVVSQFLDSKHKNHYKIYNLCAERHYDTAKFNCR
VAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGK
FLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIP
MFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKM
LKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKND
LDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTD
SDPENEPFDEDQHTQITKV
NT seq 1860 nt   +upstreamnt  +downstreamnt
ggagaagcggcggcggcggcggcggccgcggcggctgcagctccggctccggggaggggg
tccgagccgcccgtcaccatttccagggctggggacgccggagagttggtctctcccctt
ctcctgcctccaacacggcggcggcggcggcggcgcatcccgggacccgggccggtgtta
aacctcccctccgccgccgccgcactccccctggcccgggctccggaggccgccggtgga
ggcagccgttccgaggattattcgtcttctgctcattccgccgccgccgctgccaggcct
ctggctgctgaggagaagcaggcctcgtcgctgcaaccatcctcgagcagcagcagcagc
ggcagcagcagcagcagcggcagcagcagcagcagcagccgccgccgcagcagccattac
ccggctgcggtccagagccaagcggcagccgagcgaggggcatcagcgaccgccaagtcc
agagccatttccatcctgcagaagaagccccgccaccagcagcttctgccatctctctcc
tcctttttcttcagccacaggctcccagacatgacagccatcatcaaagagatcgttagc
agaaacaaaaggagatatcaagaggatggattcgacttagacttgacctgtatccatttc
tgctggctggctgatcctctttgctctttctgtcactcttctaacttagtaatttgtcca
aaggtgaatgcagcgtatttggaccacctggtgtggtacttttccgatgatcttacatca
gtgttttttaaacttttaagtgtggtatcacagtttttggattcaaagcataaaaaccat
tacaagatatacaatctatgtgctgaaagacattatgacaccgccaaatttaactgcaga
gttgcacagtatccctttgaagaccataacccaccacagctagaactcatcaaacccttt
tgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgcagcaattcactgt
aaagctggaaagggacggactggtgtaatgatttgtgcatatttattgcatcggggcaaa
tttttaaaggcacaagaagccctagatttctatggggaagtaaggaccagagataagaag
ggagtaacaattcccagtcagaggcgctatgtgtattattatagctacctgttaaagaat
catctggattatagaccagtggcactgttgtttcacaagatgatgtttgaaactattcca
atgttcagtggcggaacttgcaatcctcagtttgtggtctgccagctaaaggtgaagata
tattcctccaattcaggacccacacgacgggaagacaagtttatgtattttgagttccct
cagccgttgcctgtgtgtggtgacatcaaagtagagttcttccacaaacagaacaagatg
ctaaaaaaggacaaaatgtttcacttttgggtaaacacgttcttcataccaggaccagag
gaaacctcagaaaaagtagaaaatggaagtctatgtgatcaggaaattgatagtatttgc
agtatagaacgtgcagataacgacaaggaatatctggtacttactttaacaaaaaatgat
cttgacaaagcaaataaagacaaagccaaccgatatttttctccaaatttcaaggtgaag
ctgtacttcacaaaaacagtagaggagccatcaaatccagaggctagcagttcaacttct
gtaacaccggatgttagtgacaatgaacctgatcattatagatattctgacaccactgac
tctgatccagagaatgaaccttttgatgaagatcagcatacacaaattacgaaagtctga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (9)   
   Pfam (9)   
All databases (14)   

Download RDF
DBGET integrated database retrieval system