KEGG   DISEASE: Klebsiella infection
H00301                      Disease                                
Klebsiella infection
Klebsiella is a gram-negative bacterium of Enterobacteriaceae, which has emerged as an important cause of hospital-acquired infections. Infections caused by extended-spectrum beta-lactamase (ESBL)-producing pathogens, particularly Klebsiella pneumoniae, are increasing. ESBL are plasmid-mediated enzymes and these plasmids also carry resistance genes to other antibiotics including aminoglycosides, chloramphenicol, sulfonamides, trimethoprim, and tetracycline. Thus, Gram-negative bacilli containing these plasmids are multidrug-resistant. Klebsiella pneumoniae can cause sepsis, conjunctivitis, urinary tract infections, and surgical site infections. Bloodstream infections with Klebsiella markedly increase the rates of treatment failure and death.
Bacterial infectious disease
Human diseases in ICD-11 classification [BR:br08403]
 12 Diseases of the respiratory system
  Lung infections
   CA40  Pneumonia
    H00301  Klebsiella infection
Genome-based classification of infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by enterobacteria
   H00301  Klebsiella infection
Klebsiella pneumoniae [GN:kpn kpu kpm kpp kph kpz kpv kpw kpy kpg kpc kpq kpt kpr kpa kps kpx kpb kpnk]
Klebsiella oxytoca [GN:koe kok]
Klebsiella quasipneumoniae [GN:kqu]
Klebsiella aerogenes [GN:ear]
Klebsiella quasivariicola [GN:kqv]
Klebsiella sp. WCHKl090001 [GN:klw]
Klebsiella pasteurii [GN:kpas]
Other DBs
ICD-11: CA40.03
ICD-10: A49.8 B96.1 J15.0
MeSH: D007710
Gupta N, Limbago BM, Patel JB, Kallen AJ
Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention.
Clin Infect Dis 53:60-7 (2011)
Gupta A, Ampofo K, Rubenstein D, Saiman L
Extended spectrum beta lactamase-producing Klebsiella pneumoniae infections: a review of the literature.
J Perinatol 23:439-43 (2003)
Tumbarello M, Spanu T, Sanguinetti M, Citton R, Montuori E, Leone F, Fadda G, Cauda R
Bloodstream infections caused by extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae: risk factors, molecular epidemiology, and clinical outcome.
Antimicrob Agents Chemother 50:498-504 (2006)
Panhotra BR, Saxena AK, Al-Ghamdi AM
Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae hospital acquired bacteremia. Risk factors and clinical outcome.
Saudi Med J 25:1871-6 (2004)

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