KEGG   Dendrobates tinctorius (dyeing poison frog): 141057306
Entry
141057306         CDS       T11000                                 
Symbol
PLCB4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
dtc  Dendrobates tinctorius (dyeing poison frog)
Pathway
dtc00562  Inositol phosphate metabolism
dtc01100  Metabolic pathways
dtc04020  Calcium signaling pathway
dtc04070  Phosphatidylinositol signaling system
dtc04081  Hormone signaling
dtc04082  Neuroactive ligand signaling
dtc04261  Adrenergic signaling in cardiomyocytes
dtc04270  Vascular smooth muscle contraction
dtc04310  Wnt signaling pathway
dtc04371  Apelin signaling pathway
dtc04540  Gap junction
dtc04621  NOD-like receptor signaling pathway
dtc04912  GnRH signaling pathway
dtc04916  Melanogenesis
Module
dtc_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:dtc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    141057306 (PLCB4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    141057306 (PLCB4)
   04371 Apelin signaling pathway
    141057306 (PLCB4)
   04020 Calcium signaling pathway
    141057306 (PLCB4)
   04070 Phosphatidylinositol signaling system
    141057306 (PLCB4)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    141057306 (PLCB4)
   04081 Hormone signaling
    141057306 (PLCB4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    141057306 (PLCB4)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    141057306 (PLCB4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    141057306 (PLCB4)
   04916 Melanogenesis
    141057306 (PLCB4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    141057306 (PLCB4)
   04270 Vascular smooth muscle contraction
    141057306 (PLCB4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dtc04131]
    141057306 (PLCB4)
Enzymes [BR:dtc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     141057306 (PLCB4)
Membrane trafficking [BR:dtc04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    141057306 (PLCB4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    141057306 (PLCB4)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2 PLC-beta_C PEX14-like_2nd EF-hand_6 EF-hand_7 TetR_C_13
Other DBs
NCBI-GeneID: 141057306
NCBI-ProteinID: XP_073409953
Position
Unknown
AA seq 1227 aa
MAKPYEFNWQKPVPSFMQDGAMFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVL
ECSLINSIRYGIIPKDPKILSALESAGKAENELDGRVMCVCSGTDLVNINFTYMVAESVE
VAKQWVEGLKSITHNFRANNVSPMTCLKKHWMKLTFLTNVNGKIPVRSITRTFASGKTEK
VIFQVLKELGLPSGKNDEIEPSAFTFEKFYELTQKICPRTDIEELFKKINGDKSDYLTVD
QLVSFLNESQRDPRLNEILFPFFDTKRAMQIVEMYEPDEELKQRGHISSDGFCRYLMSDE
NAPVFLDRLELYQEMEHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM
SKYCEEIFGDLLLKQALETHPEYVTAFNKQGKGTHAQLTHELDPGKSLPSPNDLKKKILI
KNKRLKPEVEKKQLEALKSVMEAGETVAPASILEDDIEEEIENADQEEEAHPEYKFGSEL
SADDLSQKEAAANSSKKVIEDPEQENNNKKGAITADDEQAWMANYKYVGATTNIHPFLST
MINYAQPVKFQGFKVAEERNIHFNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGG
RVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGFLLKPDFMRRPDRTF
DPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNG
LNPVYNEEAFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNK
PLSLPTIFCSIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPN
DNTKNDKKGKTNNAKANVTPQTSSELRPTAASSSGTASEVKKAIDQIPQVKVEDLKQMKA
YIKQLKKQQKEINSMKKKHDKEQSSVRKVHCTQADKLVAQLDKEKLSLEKNLEKAIKKKG
GNNCVEMKKETENKIQVLTSDHKSKVKEIVAQHTKEWSELLSTQAAEVQDLQDLHLGQQC
ELLKKLLITVQEQQSQQLKLSHDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRV
RELNSSNTKKFLEERKRLAMKQSKEMDQLKKAQLEHLEILEKQNEQLLKSCHAVSHSQGK
GNPADGQTGSRDGPQASNSCVKLQNAN
NT seq 3684 nt   +upstreamnt  +downstreamnt
atggccaaaccatatgaattcaattggcagaagcctgttccttctttcatgcaagatgga
gctatgtttgacagatatgaagaggaatcatttgtgtttgaaccaaattgcctctttaaa
gtggatgaatttggcttttttctcacatggaaaagtgaaggcaaggaaggccaggtccta
gaatgttctctaatcaacagtatacgttatggcataataccaaaggatccaaaaatattg
tctgcactggagtctgctggaaaagccgagaatgaacttgacggccgggtaatgtgcgtc
tgttccggcacagacctggtgaacatcaacttcacttacatggtcgcagagagtgtcgaa
gtagctaagcaatgggtagaagggctaaaatctatcacgcataactttagagccaacaac
gtcagtccaatgacatgtctgaaaaaacactggatgaaactcacatttctcacaaacgta
aatggaaaaatcccagtccgcagtattacaagaacatttgcatctggaaaaacagaaaaa
gtgatctttcaagttcttaaagaattaggtcttccaagtggaaagaatgatgaaattgag
ccttctgcttttacatttgagaagttctatgaacttacgcaaaagatttgccccagaacg
gacatagaagagctctttaaaaaaatcaatggagacaaatctgattatttaacggtagac
caattagtgagctttctaaatgaaagtcaaagagaccctcggctcaatgaaatcttgttc
ccgttctttgacactaagcgggccatgcagatcgtagagatgtatgaacctgatgaagaa
ctgaagcaaagaggccacatttctagtgatggattttgcagatacttgatgtctgatgag
aacgcaccagtcttcttagaccgcttggagctgtaccaggagatggagcacccgctggcg
cactactttattagctcctcccacaatacgtaccttaccggcagacagtttggaggcaaa
tcttcagtagagatgtacagacaggtcctgttagctggatgcaggtgcgttgaattggat
tgctgggatggtaaaggtgaagatcaggagcctatcataacacacgggaaggcgatgtgc
acagatatcctctttaaggatgtaatacaagccatcaaggagacagcatttgtcacgtcg
gaatatcctgtaatcctgtcatttgagaatcattgcagcaaatatcaacagtacaagatg
tccaaatactgtgaagaaatatttggggatctcctactgaagcaagccctggaaacacat
ccggaatatgtcactgcattcaacaagcaaggcaaaggaacgcatgctcagctcactcat
gaactggatcctgggaaatcgttaccttctccaaatgacctgaaaaaaaaaattctcatc
aagaacaagcgtctaaagcctgaagtggaaaaaaaacaactggaggctttaaaaagtgtg
atggaggccggggagacggtggcccctgctagtatccttgaagatgacattgaggaagaa
attgaaaatgccgatcaggaggaggaagcacaccccgaatacaagtttggaagtgagctc
tcagcggacgacctgagtcaaaaagaggctgcggcaaacagctcgaaaaaggtcattgaa
gatcctgaacaagaaaacaataacaaaaagggcgcaataactgcagatgatgaacaagcg
tggatggcgaattataagtacgtaggcgccacaaccaacatacatccgtttttatctaca
atgatcaactatgcgcagccagtaaaatttcaaggtttcaaggtggcagaagaacggaac
attcatttcaacatgtcatccttcaatgagtcagtggggttggggtatctgaagacccat
gctattgagtttgtaaactataacaagcggcagatgagccgcatctaccccaagggtggg
cgagtggattccagtaattatatgcctcaaattttctggaacgccggctgccagatggtc
tctctgaactatcagaccccagatctggcaatgcagctgaaccaggggaagtttgaatac
aacggatcctgtgggttcctactaaaaccagacttcatgagacgtccagacaggacattt
gacccattctctgagactccagtggatggagtgattgcagctacctgctctgttcaggtt
atatctggacagtttctctcagacaaaaaaattgggacgtatgttgaggtggacatgtat
gggttgccaactgacaccataagaaaagagttccggactcgtatggtcatgaacaatgga
ctgaacccggtgtataatgaggaggcttttgtatttcgaaaggttatcttacctgacctt
gctgtgctaaggatagcagtgtatgatgacaacaataaactgataggacagcggatattg
ccattagatggtctccaggctggatatcggcacatttcacttcggaatgaaggcaacaag
cccctttcactgccaaccattttctgcagcattgttctgaagacctacgttccagatgga
tttggagatattgttgatgctttatcagatcctaagaagttcctgtccattactgagaaa
agggccgatcagatgagggcgatgggtattgaaacaagtgacatcgcagatgtgccaaat
gacaacacaaagaacgataaaaaagggaaaaccaataatgccaaagccaatgtgactccc
caaacaagctcggagctcaggccgacagctgcgtcctcctccgggacagcaagtgaagtt
aagaaagctatagatcaaattccacaagtgaaagtcgaagatttgaaacaaatgaaggcc
tacatcaaacagctaaagaagcagcagaaagagatcaactccatgaagaagaaacacgac
aaagagcaaagttctgtgcggaaggtacactgcacacaagctgacaaattagtggcacaa
cttgataaggaaaagttgtctcttgagaagaacttagaaaaagcaatcaagaagaaagga
ggaaataactgtgttgaaatgaagaaagaaacagaaaataaaattcaggttttaacgtca
gatcataaatccaaggtgaaagaaattgttgctcagcatacgaaagagtggtcagaactg
cttagcacacaagctgctgaagtgcaagacctccaagatctacatctaggtcaacaatgc
gaacttctcaaaaaactgctgatcaccgtccaagaacaacagtcacagcagctgaagctc
tcccatgatcgcgagagcaaggagatgagggccaatcaagctaaaatttccatggaaaac
agtaaagccataagtcaggataaatctatcaaaaataaagctgaacgtgaaagacgagtg
agggaattgaacagcagcaacacaaagaaattccttgaagaaaggaaaagactggcaatg
aaacaatcaaaggaaatggatcagttaaagaaagcccagctggaacatttagaaattctg
gagaagcagaatgaacagcttttgaaatcgtgtcacgctgtgtctcactcacaaggcaaa
ggaaatccagcagatggtcaaactggaagccgagatgggccgcaggccagcaacagttgt
gtaaagctgcagaacgcaaactga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (10)   
   RefSeq(pep) (10)   
DNA sequence (10)   
   RefSeq(nuc) (10)   
Protein domain (11)   
   Pfam (11)   
All databases (33)   

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