KEGG   Eptesicus fuscus (big brown bat): 103295577
Entry
103295577         CDS       T09083                                 
Symbol
MAPK13
Name
(RefSeq) mitogen-activated protein kinase 13
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
efus  Eptesicus fuscus (big brown bat)
Pathway
efus01522  Endocrine resistance
efus04010  MAPK signaling pathway
efus04015  Rap1 signaling pathway
efus04068  FoxO signaling pathway
efus04071  Sphingolipid signaling pathway
efus04114  Oocyte meiosis
efus04148  Efferocytosis
efus04218  Cellular senescence
efus04261  Adrenergic signaling in cardiomyocytes
efus04370  VEGF signaling pathway
efus04380  Osteoclast differentiation
efus04517  IgSF CAM signaling
efus04519  Cadherin signaling
efus04550  Signaling pathways regulating pluripotency of stem cells
efus04611  Platelet activation
efus04613  Neutrophil extracellular trap formation
efus04620  Toll-like receptor signaling pathway
efus04621  NOD-like receptor signaling pathway
efus04622  RIG-I-like receptor signaling pathway
efus04625  C-type lectin receptor signaling pathway
efus04657  IL-17 signaling pathway
efus04658  Th1 and Th2 cell differentiation
efus04659  Th17 cell differentiation
efus04660  T cell receptor signaling pathway
efus04664  Fc epsilon RI signaling pathway
efus04668  TNF signaling pathway
efus04670  Leukocyte transendothelial migration
efus04714  Thermogenesis
efus04722  Neurotrophin signaling pathway
efus04723  Retrograde endocannabinoid signaling
efus04728  Dopaminergic synapse
efus04750  Inflammatory mediator regulation of TRP channels
efus04912  GnRH signaling pathway
efus04914  Progesterone-mediated oocyte maturation
efus04917  Prolactin signaling pathway
efus04926  Relaxin signaling pathway
efus04932  Non-alcoholic fatty liver disease
efus04933  AGE-RAGE signaling pathway in diabetic complications
efus04935  Growth hormone synthesis, secretion and action
efus04936  Alcoholic liver disease
efus05014  Amyotrophic lateral sclerosis
efus05020  Prion disease
efus05022  Pathways of neurodegeneration - multiple diseases
efus05132  Salmonella infection
efus05133  Pertussis
efus05135  Yersinia infection
efus05140  Leishmaniasis
efus05142  Chagas disease
efus05145  Toxoplasmosis
efus05152  Tuberculosis
efus05161  Hepatitis B
efus05163  Human cytomegalovirus infection
efus05167  Kaposi sarcoma-associated herpesvirus infection
efus05169  Epstein-Barr virus infection
efus05170  Human immunodeficiency virus 1 infection
efus05171  Coronavirus disease
efus05205  Proteoglycans in cancer
efus05208  Chemical carcinogenesis - reactive oxygen species
efus05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
efus05415  Diabetic cardiomyopathy
efus05417  Lipid and atherosclerosis
efus05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:efus00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103295577 (MAPK13)
   04015 Rap1 signaling pathway
    103295577 (MAPK13)
   04370 VEGF signaling pathway
    103295577 (MAPK13)
   04668 TNF signaling pathway
    103295577 (MAPK13)
   04068 FoxO signaling pathway
    103295577 (MAPK13)
   04071 Sphingolipid signaling pathway
    103295577 (MAPK13)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    103295577 (MAPK13)
   04519 Cadherin signaling
    103295577 (MAPK13)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    103295577 (MAPK13)
  09143 Cell growth and death
   04114 Oocyte meiosis
    103295577 (MAPK13)
   04218 Cellular senescence
    103295577 (MAPK13)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    103295577 (MAPK13)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103295577 (MAPK13)
   04613 Neutrophil extracellular trap formation
    103295577 (MAPK13)
   04620 Toll-like receptor signaling pathway
    103295577 (MAPK13)
   04621 NOD-like receptor signaling pathway
    103295577 (MAPK13)
   04622 RIG-I-like receptor signaling pathway
    103295577 (MAPK13)
   04625 C-type lectin receptor signaling pathway
    103295577 (MAPK13)
   04660 T cell receptor signaling pathway
    103295577 (MAPK13)
   04658 Th1 and Th2 cell differentiation
    103295577 (MAPK13)
   04659 Th17 cell differentiation
    103295577 (MAPK13)
   04657 IL-17 signaling pathway
    103295577 (MAPK13)
   04664 Fc epsilon RI signaling pathway
    103295577 (MAPK13)
   04670 Leukocyte transendothelial migration
    103295577 (MAPK13)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103295577 (MAPK13)
   04914 Progesterone-mediated oocyte maturation
    103295577 (MAPK13)
   04917 Prolactin signaling pathway
    103295577 (MAPK13)
   04926 Relaxin signaling pathway
    103295577 (MAPK13)
   04935 Growth hormone synthesis, secretion and action
    103295577 (MAPK13)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103295577 (MAPK13)
  09156 Nervous system
   04728 Dopaminergic synapse
    103295577 (MAPK13)
   04723 Retrograde endocannabinoid signaling
    103295577 (MAPK13)
   04722 Neurotrophin signaling pathway
    103295577 (MAPK13)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103295577 (MAPK13)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103295577 (MAPK13)
  09159 Environmental adaptation
   04714 Thermogenesis
    103295577 (MAPK13)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103295577 (MAPK13)
   05208 Chemical carcinogenesis - reactive oxygen species
    103295577 (MAPK13)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103295577 (MAPK13)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103295577 (MAPK13)
   05161 Hepatitis B
    103295577 (MAPK13)
   05171 Coronavirus disease
    103295577 (MAPK13)
   05163 Human cytomegalovirus infection
    103295577 (MAPK13)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103295577 (MAPK13)
   05169 Epstein-Barr virus infection
    103295577 (MAPK13)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103295577 (MAPK13)
   05135 Yersinia infection
    103295577 (MAPK13)
   05133 Pertussis
    103295577 (MAPK13)
   05152 Tuberculosis
    103295577 (MAPK13)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103295577 (MAPK13)
   05140 Leishmaniasis
    103295577 (MAPK13)
   05142 Chagas disease
    103295577 (MAPK13)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103295577 (MAPK13)
   05020 Prion disease
    103295577 (MAPK13)
   05022 Pathways of neurodegeneration - multiple diseases
    103295577 (MAPK13)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103295577 (MAPK13)
   05418 Fluid shear stress and atherosclerosis
    103295577 (MAPK13)
   05415 Diabetic cardiomyopathy
    103295577 (MAPK13)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103295577 (MAPK13)
   04932 Non-alcoholic fatty liver disease
    103295577 (MAPK13)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103295577 (MAPK13)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103295577 (MAPK13)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:efus01001]
    103295577 (MAPK13)
Enzymes [BR:efus01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     103295577 (MAPK13)
Protein kinases [BR:efus01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   103295577 (MAPK13)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH RIO1 Kdo Kinase-like
Other DBs
NCBI-GeneID: 103295577
NCBI-ProteinID: XP_054577712
Position
10:6340217..6350069
AA seq 364 aa
MSLTRKKGFYKQDVNKTAWELPRTYLSPAHVGSGAYGAVCSAIDKRSGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMHHENVIGLLDVFTPASSLRSFHDFYLVMPFMQTDLQKIMGM
EFSEDKIQYLVYQMLKGLKYIHSAGVIHRDLKPGNLAVNEDCELKILDFGLARHADAEMT
GYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPGAEFVQKLKDKAAKSYIQSLPQSPKKDFSQLFPSASPQAADLLEKMLELDVDKRVTAS
QALAHPFFEPFRDPEEETEAQKFDDSLEHEKLTVDEWKQHIYKEIVNFSPIARKDSRRRS
GMKL
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgagcctcacccggaaaaagggcttctacaagcaggacgtcaacaagaccgcctgggag
ctgcccaggacctacctgtccccggcgcacgtcggcagcggggcgtatggcgccgtgtgc
tccgccatcgacaagcggtcaggggagaaggtggccatcaagaagctgagccggcccttc
cagtctgagatcttcgccaagagggcctaccgggagctgctgctgctgaagcacatgcac
catgagaacgtcatcgggctcctggatgtcttcaccccagcctcctccctgcgcagcttc
catgacttctacctggtgatgcctttcatgcagacggacctgcagaagatcatgggcatg
gagttcagtgaggacaagatccagtacctggtgtatcagatgcttaagggccttaagtac
atccactcggctggcgtcatccacagggacctgaagccaggcaacctcgctgtgaacgag
gactgcgagctgaagatcttggattttgggctggcgcggcatgcagacgccgagatgact
ggctacgtggtgacgcgctggtaccgggcccccgaggtgatcctcagctggatgcactac
aaccagactgtggacatctggtctgtgggctgcatcatggcggagatgctgacggggaaa
acgctgttcaaggggaaagattacctggaccagctgacccagatcctgaaggtgaccggg
gtgccaggtgcagagttcgtgcagaagctgaaggacaaagcggccaaatcctacatccag
tccctgccgcagagccccaagaaggacttctctcagctcttccccagcgccagcccccag
gccgcagacctgctggagaagatgctggagctggacgtggacaagcgcgtgacggcctcg
caggccctggcccaccccttctttgaacccttccgggaccccgaggaggagacggaggcc
cagaaattcgatgattccttagagcatgagaaactcaccgtggacgaatggaagcagcac
atctacaaggagatcgtgaacttcagccccattgcccggaaggactcgcggcgccggagt
ggcatgaagctgtag

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