KEGG   Eublepharis macularius (Leopard gecko): 129329994
Entry
129329994         CDS       T09084                                 
Symbol
PIK3R2
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit beta isoform X1
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
emc  Eublepharis macularius (Leopard gecko)
Pathway
emc04012  ErbB signaling pathway
emc04068  FoxO signaling pathway
emc04070  Phosphatidylinositol signaling system
emc04081  Hormone signaling
emc04140  Autophagy - animal
emc04145  Phagocytosis
emc04150  mTOR signaling pathway
emc04210  Apoptosis
emc04218  Cellular senescence
emc04370  VEGF signaling pathway
emc04510  Focal adhesion
emc04517  IgSF CAM signaling
emc04518  Integrin signaling
emc04620  Toll-like receptor signaling pathway
emc04625  C-type lectin receptor signaling pathway
emc04810  Regulation of actin cytoskeleton
emc04910  Insulin signaling pathway
emc04914  Progesterone-mediated oocyte maturation
emc05100  Bacterial invasion of epithelial cells
emc05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:emc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    129329994 (PIK3R2)
   04370 VEGF signaling pathway
    129329994 (PIK3R2)
   04068 FoxO signaling pathway
    129329994 (PIK3R2)
   04070 Phosphatidylinositol signaling system
    129329994 (PIK3R2)
   04150 mTOR signaling pathway
    129329994 (PIK3R2)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    129329994 (PIK3R2)
   04517 IgSF CAM signaling
    129329994 (PIK3R2)
   04518 Integrin signaling
    129329994 (PIK3R2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    129329994 (PIK3R2)
   04140 Autophagy - animal
    129329994 (PIK3R2)
  09143 Cell growth and death
   04210 Apoptosis
    129329994 (PIK3R2)
   04218 Cellular senescence
    129329994 (PIK3R2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129329994 (PIK3R2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    129329994 (PIK3R2)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    129329994 (PIK3R2)
   04625 C-type lectin receptor signaling pathway
    129329994 (PIK3R2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    129329994 (PIK3R2)
   04914 Progesterone-mediated oocyte maturation
    129329994 (PIK3R2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    129329994 (PIK3R2)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    129329994 (PIK3R2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:emc04131]
    129329994 (PIK3R2)
Membrane trafficking [BR:emc04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    129329994 (PIK3R2)
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 RhoGAP ATG11 SH2_1 SH3_1 Laminin_I SH3_9
Other DBs
NCBI-GeneID: 129329994
NCBI-ProteinID: XP_054835779
UniProt: A0AA97JET6
Position
5:4579556..4593645
AA seq 739 aa
MEGTEGYQYRAVYPYHKEREEDIDLLPGDTLVVSRAALQALGFKDGDEQVPNQIGWILGV
NERTKQKGDFPGTYVEYVGPIKICVPSYRPRMTRPLPAAPAAGASHVQEALEQGLILPEL
LEQLVPPEVAPPLLSRLVGAIERKGLDCEMLYRTPGSELRQAQRNSWPLAGDLEAWDVLS
LGEGLKRYLQELPTPVVPDRVHGEILQVLQDASPPELVRTQLLSVLDPPGLPLPHLLTLQ
FLLRHLAKVAEEAESNGLRPRVLGEIFGPLLLRRPAAASSEMNPDFSVLFLETLLWTMKP
KQALPPPALPPKPPKPKPAAVALTNGNGVALQDAEWYWGDISREEVNEKLRDTPDGTFLV
RDASSKIQGEYTLTLRKGGNNKLIKIFHREGKYGFSEPLTFSSVVELINHYRYESLAQYN
AKLDTRLLYPISKYQQDQVVKEDSVEAVGEQLKVYHQQYQDKSREYDLLYEEYMRTSQEL
QMKRTAIEAFNETIKIFEEQSQVQERCSREYIERFRREGNEKELQRILMNSEKLQSRVSE
IHDSKRKLQQDLKQQALENREIDKRMNSLKPDLLQLRKLRDQYLVWLTQKGTRQKKINEW
LGIRNETEDQYFMIEDEEELPHHEERTWYVGKIDRTQAEEMLAGKRDGTFLIRESSHPGC
YACSVVVEGDTKHCMIYKTETGYGFAEPYNLYASLKELVLHYRHTSLMQHNDSLSVTLAH
PILSPPPPRLRSGTLPVDL
NT seq 2220 nt   +upstreamnt  +downstreamnt
atggagggcactgaagggtaccagtaccgggccgtctacccataccacaaggagcgagag
gaggacattgatctgctacctggagacaccttggtggtgagcagagcagccctgcaggcc
ctgggcttcaaggatggtgatgagcaggtgcccaaccagattggctggattctgggtgtc
aacgagcgcaccaagcaaaagggggacttcccaggcacatacgtggagtatgttggaccc
atcaagatctgtgtgccatcctaccggcccaggatgactcggcccctcccagctgcccct
gcggctggtgcctcccatgtgcaggaggccttggaacaggggttgatccttccggagctt
ctggagcagctcgttccccctgaggttgcccctcctttgctgagccgactggtgggcgcc
attgaaaggaaagggctggattgtgagatgctgtacaggacgcctggctccgaactgagg
caagcacagagaaacagctggcctctggctggcgacttggaggcttgggatgtgctgtcc
ctgggcgaaggcctcaagaggtacctgcaagagctgccaaccccagtcgtgcctgacaga
gtgcatggggagatcctgcaagtgctgcaggatgccagcccacctgaacttgtacggaca
cagctgctctctgtattagatccgcctggccttcctctgccccatcttctcaccctccag
ttcctcctgcgtcacttggcaaaagtggctgaagaagctgagagcaacgggctgcggccc
cgtgtcctgggcgagatcttcgggcctctgctccttcggaggcctgccgctgccagctct
gagatgaaccctgacttctctgtgctgttcctggagactcttctgtggaccatgaagccc
aagcaggcactgcccccgccagctctgccccccaagccccccaagccaaagcctgcagcg
gtagccctgaccaatgggaacggcgtggctctgcaggatgccgagtggtactggggtgac
atctccagggaggaagtgaacgaaaagctccgagacactccagacggcaccttccttgtt
cgagacgcatccagcaagattcaaggcgaatacactctgacgctgcggaaggggggcaac
aacaagctgatcaagattttccatcgggagggcaagtacggtttctcagagccactgacc
ttcagctccgtggtggagctcatcaatcattatcggtatgagtctctggcccagtacaat
gccaaactggacacacggctgctgtaccccatctccaagtaccagcaggaccaggtggtg
aaggaggacagtgtggaagctgttggggagcagctcaaggtctaccaccagcagtaccaa
gacaaaagccgcgagtacgaccttctctatgaggagtatatgcgcacctcgcaggagttg
cagatgaagagaacagccatcgaggccttcaatgagaccatcaagatctttgaggagcag
agccaggtgcaggaaaggtgcagccgggagtacattgagcgtttccggagggaggggaac
gagaaggagctgcagcggatcctgatgaactcggagaagcttcagtcccgcgtctccgag
atccatgacagcaagaggaagctgcagcaggatctcaagcagcaagccttggagaatcgc
gagattgacaagcgcatgaacagtctcaagcccgacctactgcagctgcgcaaactccgg
gaccaatacttggtgtggctgacccaaaagggaacccgccagaagaaaatcaatgagtgg
ctgggcatcaggaacgagactgaggaccagtacttcatgatagaggatgaggaggagcta
ccccaccatgaggagcggacatggtacgttggcaagattgaccgcacccaagctgaagag
atgctggctggcaagcgggatgggaccttcctcatccgggagagcagccaccctggctgt
tacgcctgctcagttgtggtggagggcgacaccaagcactgcatgatctacaagacggag
acaggctatggcttcgccgagccttacaacctctatgcctcgctgaaggagctggtcttg
cactacaggcacacctcactgatgcagcacaatgactcgctcagtgtcacgctggcacac
cccatcctctccccacctccacccaggctgaggtcgggcacgctgcctgtggatttatga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (8)   
   Pfam (8)   
All databases (15)   

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