KEGG   Equus przewalskii (Przewalski's horse): 103542193
Entry
103542193         CDS       T04644                                 
Symbol
PLCB3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
epz  Equus przewalskii (Przewalski's horse)
Pathway
epz00562  Inositol phosphate metabolism
epz01100  Metabolic pathways
epz04015  Rap1 signaling pathway
epz04020  Calcium signaling pathway
epz04022  cGMP-PKG signaling pathway
epz04062  Chemokine signaling pathway
epz04070  Phosphatidylinositol signaling system
epz04071  Sphingolipid signaling pathway
epz04072  Phospholipase D signaling pathway
epz04081  Hormone signaling
epz04082  Neuroactive ligand signaling
epz04261  Adrenergic signaling in cardiomyocytes
epz04270  Vascular smooth muscle contraction
epz04310  Wnt signaling pathway
epz04371  Apelin signaling pathway
epz04540  Gap junction
epz04611  Platelet activation
epz04613  Neutrophil extracellular trap formation
epz04621  NOD-like receptor signaling pathway
epz04713  Circadian entrainment
epz04720  Long-term potentiation
epz04723  Retrograde endocannabinoid signaling
epz04724  Glutamatergic synapse
epz04725  Cholinergic synapse
epz04726  Serotonergic synapse
epz04728  Dopaminergic synapse
epz04730  Long-term depression
epz04742  Taste transduction
epz04750  Inflammatory mediator regulation of TRP channels
epz04911  Insulin secretion
epz04912  GnRH signaling pathway
epz04915  Estrogen signaling pathway
epz04916  Melanogenesis
epz04918  Thyroid hormone synthesis
epz04919  Thyroid hormone signaling pathway
epz04921  Oxytocin signaling pathway
epz04922  Glucagon signaling pathway
epz04924  Renin secretion
epz04925  Aldosterone synthesis and secretion
epz04926  Relaxin signaling pathway
epz04927  Cortisol synthesis and secretion
epz04928  Parathyroid hormone synthesis, secretion and action
epz04929  GnRH secretion
epz04933  AGE-RAGE signaling pathway in diabetic complications
epz04934  Cushing syndrome
epz04935  Growth hormone synthesis, secretion and action
epz04961  Endocrine and other factor-regulated calcium reabsorption
epz04970  Salivary secretion
epz04971  Gastric acid secretion
epz04972  Pancreatic secretion
epz04973  Carbohydrate digestion and absorption
epz05010  Alzheimer disease
epz05016  Huntington disease
epz05017  Spinocerebellar ataxia
epz05022  Pathways of neurodegeneration - multiple diseases
epz05142  Chagas disease
epz05143  African trypanosomiasis
epz05146  Amoebiasis
epz05163  Human cytomegalovirus infection
epz05200  Pathways in cancer
epz05415  Diabetic cardiomyopathy
epz05417  Lipid and atherosclerosis
Module
epz_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:epz00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    103542193 (PLCB3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    103542193 (PLCB3)
   04310 Wnt signaling pathway
    103542193 (PLCB3)
   04371 Apelin signaling pathway
    103542193 (PLCB3)
   04020 Calcium signaling pathway
    103542193 (PLCB3)
   04070 Phosphatidylinositol signaling system
    103542193 (PLCB3)
   04072 Phospholipase D signaling pathway
    103542193 (PLCB3)
   04071 Sphingolipid signaling pathway
    103542193 (PLCB3)
   04022 cGMP-PKG signaling pathway
    103542193 (PLCB3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    103542193 (PLCB3)
   04081 Hormone signaling
    103542193 (PLCB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    103542193 (PLCB3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103542193 (PLCB3)
   04613 Neutrophil extracellular trap formation
    103542193 (PLCB3)
   04621 NOD-like receptor signaling pathway
    103542193 (PLCB3)
   04062 Chemokine signaling pathway
    103542193 (PLCB3)
  09152 Endocrine system
   04911 Insulin secretion
    103542193 (PLCB3)
   04922 Glucagon signaling pathway
    103542193 (PLCB3)
   04929 GnRH secretion
    103542193 (PLCB3)
   04912 GnRH signaling pathway
    103542193 (PLCB3)
   04915 Estrogen signaling pathway
    103542193 (PLCB3)
   04921 Oxytocin signaling pathway
    103542193 (PLCB3)
   04926 Relaxin signaling pathway
    103542193 (PLCB3)
   04935 Growth hormone synthesis, secretion and action
    103542193 (PLCB3)
   04918 Thyroid hormone synthesis
    103542193 (PLCB3)
   04919 Thyroid hormone signaling pathway
    103542193 (PLCB3)
   04928 Parathyroid hormone synthesis, secretion and action
    103542193 (PLCB3)
   04916 Melanogenesis
    103542193 (PLCB3)
   04924 Renin secretion
    103542193 (PLCB3)
   04925 Aldosterone synthesis and secretion
    103542193 (PLCB3)
   04927 Cortisol synthesis and secretion
    103542193 (PLCB3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103542193 (PLCB3)
   04270 Vascular smooth muscle contraction
    103542193 (PLCB3)
  09154 Digestive system
   04970 Salivary secretion
    103542193 (PLCB3)
   04971 Gastric acid secretion
    103542193 (PLCB3)
   04972 Pancreatic secretion
    103542193 (PLCB3)
   04973 Carbohydrate digestion and absorption
    103542193 (PLCB3)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    103542193 (PLCB3)
  09156 Nervous system
   04724 Glutamatergic synapse
    103542193 (PLCB3)
   04725 Cholinergic synapse
    103542193 (PLCB3)
   04728 Dopaminergic synapse
    103542193 (PLCB3)
   04726 Serotonergic synapse
    103542193 (PLCB3)
   04720 Long-term potentiation
    103542193 (PLCB3)
   04730 Long-term depression
    103542193 (PLCB3)
   04723 Retrograde endocannabinoid signaling
    103542193 (PLCB3)
  09157 Sensory system
   04742 Taste transduction
    103542193 (PLCB3)
   04750 Inflammatory mediator regulation of TRP channels
    103542193 (PLCB3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    103542193 (PLCB3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103542193 (PLCB3)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    103542193 (PLCB3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    103542193 (PLCB3)
   05142 Chagas disease
    103542193 (PLCB3)
   05143 African trypanosomiasis
    103542193 (PLCB3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103542193 (PLCB3)
   05016 Huntington disease
    103542193 (PLCB3)
   05017 Spinocerebellar ataxia
    103542193 (PLCB3)
   05022 Pathways of neurodegeneration - multiple diseases
    103542193 (PLCB3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103542193 (PLCB3)
   05415 Diabetic cardiomyopathy
    103542193 (PLCB3)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    103542193 (PLCB3)
   04934 Cushing syndrome
    103542193 (PLCB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:epz04131]
    103542193 (PLCB3)
Enzymes [BR:epz01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     103542193 (PLCB3)
Membrane trafficking [BR:epz04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    103542193 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    103542193 (PLCB3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 103542193
NCBI-ProteinID: XP_070421473
UniProt: A0ABM4JZV3
Position
11:25845387..25862784
AA seq 1230 aa
MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRVDANGFFLYWTGPNME
VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVAGPDPVNTTFLNF
MAVQDDTAKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS
ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LTLEQLMDFINQKQRDPRLNEVLYPPLRHSQARQLIEKYEPNQQFLERDQMSMEGFSRYL
GGEENGILPLEALDLSADMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC
VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK
QQAKMAEYCRSIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHQPSTGVPGS
SVRKRPLEQSNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVALEKPSLEPQKSLGE
EGPQRGPDALGPVDREDEEEDEEEEEQTDPKKPTTDEGTASSEVNATEEMSTLVNYIEPV
KFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYM
PQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIV
DGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEP
FDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYICLRNEANQPLCLPALLI
YTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQAGPETCQETQSQQL
GSQLTPNPTPSTLDTSPRRPPGTVTSPTSPSLSSPGQRDDLVASILAEVAPAPLDELRGH
KALVKLRSRQERDLRELRKKHQRKAVALTRRLLDGLAQARAEGRCRPRPGGLGGEDEKEE
EKEVKHYQEFQKRQVQSLLELREAQADTESKWRLEHLRQAQQRLREVVLDAHTTQLKRLK
ETNDREKKELQKILDRKRHNSISEAKTREKHKKEAELTEINRRHITESVNSIRRLEEAQK
QRQERLVAGQQQVLQQLAEEEPKLLAQLAQECQEQRARLPQEVRRSLLGETPEGLGDGHL
VACASNGHAPGSSGHLSGADSESQEENTKL
NT seq 3693 nt   +upstreamnt  +downstreamnt
atggcaggcgccaggcccggcgtccacgcgctgcagctggagccgcccaccgtggtggag
accctgcggcgcgggagtaagttcatcaaatgggacgaggaggcctccagtcggaacctg
gtgaccctgcgcgtggacgccaatggcttctttttgtactggacaggacccaacatggaa
gtggacacactggacatcagttccatcagggacacgcggacaggccgttacgcccgcctg
cccaaggaccccaagatccgggaggtgctgggctttgggggccccgatgcccggctggag
gagaagctgatgacggtggtggccgggccagacccggtgaacacgacattcttgaacttc
atggccgtgcaggacgacacagccaaggtctggtccgaggagctgttcaagctggctatg
aacatcctggctcagaatgcctcccggaacaccttcttgcgcaaagcatacacgaagctg
aagctgcaggtgaaccaggatgggaggatcccggtgaagaacatcctgaagatgttctca
gcagacaagaagcgggtggaaactgcgctggaatcctgtggcctcaatttcaatcggagc
gagtccatccggcccgacgagttttccttggaaatcttcgagcggttcctgaacaagctg
tgtctgcggccggacattgacaagatcctgctggagataggcgccaagggcaagccatac
ctgacgctagagcagctcatggacttcatcaaccagaagcagcgggacccgaggctcaac
gaggtgctgtacccgcccctgcggcactcccaggcgaggcagctcatcgagaagtacgaa
cccaaccagcagttcctggagcgagaccagatgtccatggaaggtttcagccgctacctg
ggaggtgaggagaacggcatcctgcccctggaggccctggacctgagcgccgacatgacg
cagccgctcagtgcttacttcatcaactcttcccataacacctacctcacggcggggcag
ctggccgggacctcgtcggtggagatgtaccggcaggcgctgctgtggggctgccgctgc
gtggagctggacgtgtggaaggggcggccgcccgaggaggagccattcatcacgcacggc
ttcaccatgaccaccgaggtgccgctgcgggacgtgctcgaggccatcgcggagaccgcc
ttcaagacctcgccctaccccgtcatcctctccttcgagaaccacgtggactcggcaaag
cagcaggccaagatggccgagtactgccgctccatctttggggacgcgctgctcatcgac
ccactggacaagtacccgctggccccaggcgtccccctgcccagcccccaggacctgatg
ggccgcatcctggtgaagaataagaagcggcaccagcccagcacgggcgtccccggcagc
tccgtgcgcaagaggccgctggagcagagcaactcggccctgagcgagagctctgccgcc
accgagccttcctcgccccagctcgggtcccccagctccgacagctgccccggcctgagc
aacggggaggaggtggccctcgagaagcccagcctggagcctcagaagtctctgggggag
gaggggccgcagcggggccccgatgctcttggacctgttgaccgcgaggatgaggaggaa
gacgaggaagaggaggaacagacggaccccaaaaagcccaccacggatgagggcaccgcc
agcagcgaggtcaatgccacagaggaaatgtcgaccctcgtcaactacatcgagcccgtc
aagttcaagtccttcgaggctgcccgaaagaggaacaagtgcttcgagatgtcgtccttc
gtggagaccaaggccatggagcagctgaccaagagccccatggagttcgtggaatacaac
aagcagcagctgagccgtatctaccccaagggcacccgcgtggactcgtctaactacatg
ccccagctcttctggaatgtgggctgccagcttgtcgcgctcaacttccagaccctggat
gtggcgatgcagctcaacgcgggcgtgttcgagtacaacgggcgcagcggctacctgctt
aaacccgagttcatgcggcggccggacaagtcctttgaccccttcaccgaggtcatcgtg
gatggcatcgtggccaatgccttgcgggtcaaggtgatctcggggcagttcctgtccgac
aggaaggtgggcatctacgtggaggtggatatgttcggcctccctgtggacacgcggcgc
aagtaccgcacgcggacctctcaggggaactcgttcaaccccgtgtgggatgaggagccc
ttcgacttccccaaggtggtgctgcccacgctggcttcactgcgcatcgcggcttttgag
gagggcggcaagttcgtggggcaccggatcctgcccgtctctgccatccgctcagggtac
cactacatctgcctgcggaacgaggccaaccagccgctgtgcctgccggccctgctcatc
tacaccgaggcctccgactacatccctgacgaccaccaggactacgcagaggccctgatc
aaccccatcaagcatgtcagcctgatggaccagagggccaagcagctggctgccctcatt
ggggagagcgaggctcaggctggcccggagacatgccaggagacccagtctcagcagctg
gggtcccagctgaccccaaaccccacacccagcacactggacacctccccccgccggccc
ccaggcactgtcacctcccccaccagtccgtccctcagcagcccaggccaacgggatgat
ctcgtcgccagcatcctcgcagaggtggccccagccccactggacgagctccgaggccac
aaggctctggtgaagctccggagccggcaggagcgagacctgcgggagctgcgcaagaag
catcagcggaaggccgtagccctcactcgccgcctgctcgacggcctggcccaggctcgg
gccgagggcaggtgccggccccggccaggtggcctaggcggggaggacgagaaggaggag
gagaaagaggtgaagcactatcaggagttccagaaaagacaggtgcagagtctgctggag
ctgagggaggcccaggccgacacagagagcaagtggaggctggagcacctgcgacaggct
cagcagcggctcagggaggttgtcctggatgcacacacaacccagttaaagaggctgaag
gagacgaacgacagggagaagaaggaactgcagaagatcctggacaggaagcgccacaac
agtatctcggaggccaagacaagggagaaacataagaaggaggcggaactgaccgagatc
aaccgtcggcacatcactgagtcggtcaactccatccgtcggctggaggaggcccagaag
cagcggcaggagcgccttgtggccgggcagcagcaggtcctgcagcagctggcagaagag
gagcccaagctgctggcccagctggcccaggagtgtcaggagcagcgggcaaggctgccc
caggaggtccgccggagcctgctgggcgagacgccggaggggctgggggacgggcatctg
gtggcctgtgccagcaacggtcacgcgcccgggagcagcgggcacctgtctggtgctgac
tcggagagccaagaggagaatacgaagctctga

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (15)   

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