KEGG   Equus przewalskii (Przewalski's horse): 103544756
Entry
103544756         CDS       T04644                                 
Symbol
APC2
Name
(RefSeq) adenomatous polyposis coli protein 2 isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
epz  Equus przewalskii (Przewalski's horse)
Pathway
epz04310  Wnt signaling pathway
epz04390  Hippo signaling pathway
epz04519  Cadherin signaling
epz04550  Signaling pathways regulating pluripotency of stem cells
epz04810  Regulation of actin cytoskeleton
epz04934  Cushing syndrome
epz05010  Alzheimer disease
epz05022  Pathways of neurodegeneration - multiple diseases
epz05165  Human papillomavirus infection
epz05200  Pathways in cancer
epz05206  MicroRNAs in cancer
epz05210  Colorectal cancer
epz05213  Endometrial cancer
epz05217  Basal cell carcinoma
epz05224  Breast cancer
epz05225  Hepatocellular carcinoma
epz05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:epz00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    103544756 (APC2)
   04390 Hippo signaling pathway
    103544756 (APC2)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    103544756 (APC2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    103544756 (APC2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103544756 (APC2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103544756 (APC2)
   05206 MicroRNAs in cancer
    103544756 (APC2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103544756 (APC2)
   05225 Hepatocellular carcinoma
    103544756 (APC2)
   05226 Gastric cancer
    103544756 (APC2)
   05217 Basal cell carcinoma
    103544756 (APC2)
   05213 Endometrial cancer
    103544756 (APC2)
   05224 Breast cancer
    103544756 (APC2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    103544756 (APC2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103544756 (APC2)
   05022 Pathways of neurodegeneration - multiple diseases
    103544756 (APC2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    103544756 (APC2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:epz01009]
    103544756 (APC2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:epz03036]
    103544756 (APC2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:epz04812]
    103544756 (APC2)
Protein phosphatases and associated proteins [BR:epz01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     103544756 (APC2)
Chromosome and associated proteins [BR:epz03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    103544756 (APC2)
Cytoskeleton proteins [BR:epz04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     103544756 (APC2)
SSDB
Motif
Pfam: APC_basic APC_rep APC_N_CC Suppressor_APC Arm_APC_u3 Arm SAMP APC_r ZER1-like_2nd ARM_PUB SSNA1 PEA2_C MPS2 Sec7-like_HUS bZIP_1 PDC10_C Par-4_C Wtap HALZ
Other DBs
NCBI-GeneID: 103544756
NCBI-ProteinID: XP_070478413
UniProt: A0ABM4PMI7
Position
6:828603..852376
AA seq 2302 aa
MGLLGLLSLLHSAFFGDQTLQELKMTSSVAPYEQLVRQVEALKAENSHLRQELRDNSSHL
SKLETETSGMKEVLKRLQGKLEQEARVLVSSGQTEVLEQLKALQMDITSLYNLKFQPPAL
GPEPAAQTPEGSPVHGSGPSKDSFGELSRATIRLLEELDRERCFLLNEIEKEEKEKLWYY
SQLQGLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRA
SRLEQIDKELLSAQDRVQQTEPQALLAVKSMPLDEDTETEVPTHPEDGAPQPGNSKVEVV
FWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGTEAGPGGRNGNPG
APGAKDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDGGPE
GGGAGGAPVPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQAVAELLQVDYEMHGMTRD
PLNLALRRYAGMTLTNLTFGDVANKAALCARRGCMEAIVAQLASESEELHQVVSSILRNL
SWRADINSKKVLREVGSMTALMQCVLRATKESTLKSVLSALWNLSAHSTENKAAICQVDG
ALGFLVSTLTYKCQSSSLAIMESGGGILRNVSSLIATREDYRQVLRDHHCLQTLLQHLTS
HSLTIVSNACGTLWNLSARSARDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLA
HRPAKYQAAAAAVSPGACAPSLYVRKQRALEAELDARHLAQALDRLEAQGPPEAEAAAKK
PLPPLRHLDGLARDYASDSGCFDDDDAPSLAAAAATAEPASPAVLSLFLGSPFLQGQALA
RAPPARRGAPEAEKEAGGEAAVAARAKAKLALAVARIDRLVEDISALHTSSDDSFSLSSG
DPGQEAPREGRAQSCSPCRGPDGGRREAGSRAHPLLRLKAAHASLSNDSLNSGSTGDGPG
PREHTRPCQLAALAEYREGPPCTQARPSRLDLDPPGAQPKPAAQDAAAADARVRTIKLSP
TYQHVPLLEGAGRAGSGPPGAGSRKQAWLPAEALSKVPEKLGAEAAALCLSRCSSLSSLS
SAGRPGPSEAGDLDDSDSSLEGLEEAGPSEAALDGAWRGPGAASLPMAIPAPRRGRGLGV
EDATPSSSSENCVQETPLVLSRCSSVSSLGSFESPSIASSIPSDPCSGLGSGTVSPSELP
DSPGQTMPPSRSKTPPPAPAPPGERESTQFSLQWESYVKRFLDIADCRERCRLPSELDAG
SVRFTVEKPDENFSCASSLSALALHEHYVQKDVELRLLPPACPERGGGGGGGPGLHFAGH
RRRDEAAGRLEGPTAAEQELELLRECLGAAVPARLRKVASALVPGRRALPVPVYMLVPAP
AREDDSCTDSAEGTQANFSSTASLSDETLQGPPRDAPGGRADRQKPAGRAVPARQVVGHR
HRAGGAGRSWEQARGASRSRTGLELPLRRPPSAHTDGDGSHAGRARGDGALQSLCLTTPT
EEAVYCFYGDDSDEEPSRAAATPRRPSAIPRAVKRERPAGRKEAQAVPKPVPKPAPPARA
QPSLIADETPPRCSLSSSASSLGEPEPPAPAASRPRAREVAVTKDPGPGGGLAGSPSPRA
QAELLRRGIGSALPRRRPQAPAPRRRKPQAAQPDERPADGAQERGEEAAGSDHASDLDSV
EWRAIQEGANSIVTWLHQAAAAAATSEASSESDSILSFMSGLSVGSTLQPSPHRKGPRPR
AEGQAGSGVRPEKRDAALAQRGSGPRSSCGPEKPRGAQKTVSGVPAVLRGRTVIYVPSPA
PRAPPKAAPSPRAAPRKMGPPSPAQPAAPTKAPGLGQPRSRSLHRPGKISELVALSPPQR
SATPPARLAKTPSSSSSQTSPASQPLPRRSPPATQATGPLPGPGSSALPKTPARALLAKQ
HKTQKSPVRIPFMQRPARRGPPPLARAALEPGPRGRAGAEGGPGARGGRLGLVRVASARS
SGSESSDRSGFRRQLTFIKESPGLPRRRRAEPATSASTSATIPASQGGSPRRGRPALPAV
FLCSSRCDELRAAPRQAPGPHRLPAARPGPGERPPRRTSSESPSRLPVRTPAARPETVKR
YASLPHISMARRPDGAAPAPTADATRRSSDGEARPLPRVAAPGTTWRRIRDEDVPHILRS
TLPATALPLRGASPEEGPGGPPQRKTSDAVVQTEDFVATKTNSSTSPSLESREPPQVPAS
GPISLLGSDVDGPTPAKAPAAATFVHEGLVVAAGGFPASRHGSPSRSARVPPFNYVPSPM
VVAPTDSAVEKAPAAAPASLLE
NT seq 6909 nt   +upstreamnt  +downstreamnt
atggggctcctggggctgctgagcctgctgcactcggccttcttcggggaccagacgctg
caggagctgaagatgacgagctccgtggcgccctacgagcagctggtgcggcaggtggag
gccttgaaggccgagaacagtcacctgaggcaggagctgcgggacaactcgagccacctg
tccaagctggagacggagacgtccggcatgaaggaggtcctgaagcgtttgcagggcaag
ctggagcaggaggcccgagtgctggtgtcctcgggccagacagaggtgctggagcagctg
aaagccctgcagatggacatcactagcctgtacaacctcaagttccagcccccagccctg
ggccccgagcccgctgcccagacccccgagggaagcccagtacacggctccgggccctct
aaggacagctttggggagctgagccgggccaccatccggctgctggaggaactggaccga
gaacggtgcttcctgttgaatgagattgagaaggaggagaaggagaagctctggtattac
tcgcagctgcagggcctgtccaagcgcctggacgagctcccgcacgtggagacgcagttc
tcgatgcagatggacctgatccggcagcagctggagttcgaggcccagcacatccgctcg
ctgatggaggagcgcttcggcacctcggacgagatggtgcagcgggcgcagatccgtgct
tcgcgcctggagcagatcgacaaggaattgctgtctgcgcaggaccgggtgcagcagacg
gagccccaggccctgctggcggtgaagtcgatgccactggacgaggacacggagactgag
gtccccacgcaccctgaggatggtgcccctcagccgggcaacagcaaggtggaggtggtc
ttctggctgctatccatgctggcgacgcgcgaccaggaggacacggcacgcacgctgctc
gccatgtccagctctcccgagagctgtgtggccatgcgccgctcgggctgcctgccgctg
ctgctgcagatcctgcacggcaccgaggccgggcctgggggtcgtaacgggaaccccggg
gcaccgggagccaaggacgcgcgcatgcgcgccaacgcggcgctgcacaacatcgtcttc
tcgcagcctgaccagggcctggcgcgcaaggagatgcgcgtcctgcacgtgctggagcag
atccgcgcctactgcgagacctgctgggactggctgcaggcccgggacggcgggcccgag
gggggcggcgccggcggcgcccccgtccccatcgagccgcagatctgccaggccacgtgt
gccgtgatgaagctgtccttcgatgaggagtatcgccgggccatgaacgagctgggcggg
ctgcaggccgtggcggagttgctgcaggtcgactacgagatgcacgggatgacccgggac
ccactcaacctcgccctgcgccgatacgccggcatgaccctcaccaatctcacctttggg
gacgtcgccaacaaggccgcactgtgcgcgcgccggggctgcatggaggccatcgtggcc
cagctggcgtccgagagtgaggagctccaccaggtggtgtccagcatcctgcgcaacctc
tcctggcgggctgacatcaacagcaagaaggtgctgagggaggtcggcagcatgacggcc
ctgatgcagtgtgtcctgagagccaccaaggagtccaccctgaagagcgtgctcagcgcc
ctgtggaacctctcggcgcacagcacggagaacaaggcggccatctgccaggtggacggc
gccctgggcttcctggtgagcacgctgacctacaagtgccagagcagctcgctggccatc
atggagagcggcggcggcatcctgcgcaacgtgtccagcctcatcgccacccgcgaggac
tacaggcaggtgctgcgggaccaccactgcctgcagacgctgctgcagcacctcacgtcg
cacagcctgaccatcgtgagcaacgcgtgcggcacgctctggaacctgtcggcccgcagc
gcgcgcgaccaggagctgctgtgggacctgggcgcggtgggcatgctgcgcaacctggtg
cactccaagcacaagatgatcgccatgggcagcgccgcggccctgcgcaacctgctggcc
caccggcccgccaagtaccaggcggccgccgccgccgtgtccccgggcgcctgcgcgccc
agcctgtacgtgcgcaagcagcgcgcgctcgaggccgagctggacgcgcgccacctggcc
caggcgctcgaccgcctggaggcgcagggcccgccagaggccgaggccgccgccaagaag
ccgctgccgccgctgcgccacctggacgggctggcccgcgactacgcctcggactccggc
tgcttcgacgacgacgacgcgccctccctggccgccgcggccgccaccgccgagccggcc
agccccgccgtgctgtccctcttcctgggcagccccttcctgcagggccaggcgctggcc
cgcgccccgcccgcccgccgcggcgccccggaggccgagaaggaggccggcggtgaggcg
gccgtggcggccagggccaaggccaagctggcgctggcggtggcgcggatcgaccggctg
gtggaggacatctcggccctgcacacctcatccgacgacagcttcagcctcagctccggg
gaccctgggcaggaggcgcctcgggagggccgcgcccagtcctgctcgccctgccggggg
cccgacggcgggcggcgggaggcgggcagccgggctcacccgctgctgcggctcaaggcg
gcccacgccagcctctccaacgacagcctcaacagcggcagcaccggcgacgggccgggt
ccccgtgagcacacgcggccctgtcagctggccgcgctggccgagtaccgcgaggggccc
ccgtgcactcaggcgcggcccagccgccttgaccttgacccgccgggggcccagcccaag
ccggcagcccaggacgccgcggccgccgacgcccgcgtgcgcaccatcaagctgtcgccc
acctaccagcacgtgccgctgctcgagggcgcgggcagggcgggctccgggccgccaggt
gcagggtcccggaagcaggcctggctgcccgcagaggccctgagcaaggtgccggagaag
ctgggggcggaggcggctgcgctctgcctgtcccgctgcagctccctgtcctcgctgtcc
tcggccggccgcccggggcccagcgaggccggggacctggacgacagtgactcgtccctg
gaggggctggaggaggcgggccccagcgaggcggcgctggacggggcctggcgggggccg
ggggccgcctccctgcccatggccatcccggcgccgcggcggggccggggcctgggggtg
gaggacgccacgccgtccagctcctcggagaactgcgtgcaggagacgccgctggtgctg
agccgctgcagctcggtgagctcgctgggcagcttcgagagcccgtccattgccagctcc
atccccagcgacccgtgcagcgggctgggcagcggcacggtcagccccagcgagctgccc
gacagccccgggcagaccatgccgccgagccgcagcaagacgccgccgccggcgcccgcg
cccccgggcgagcgcgagagcacgcagttcagcctgcagtgggagagctacgtgaagcgg
ttcctggacatcgccgactgccgcgagcgctgccgcctgccctccgagctggacgcgggc
agcgtgcgcttcaccgtggagaagccggacgagaacttctcgtgcgcctccagcctcagc
gcgctcgccctgcacgagcactacgtgcagaaggacgtggagctgcggctgctgccgccg
gcctgccccgagcggggcggcgggggtggcggaggccccggcctgcacttcgccgggcac
cgtcggcgggacgaggccgctggccgcctcgaggggccgacggccgctgagcaggagctg
gagctgctgcgagagtgcctgggcgcggccgtgcccgcccggctccgcaaggtggcctcg
gcgctggtgcccggccgccgcgcgctgccggtgcccgtctacatgctggtgcccgccccg
gcccgcgaggacgactcgtgcactgactcggccgagggcacgcaggccaacttctccagc
accgcctcgctcagcgacgagacgctgcaggggccccccagggacgcgcccggcgggcgt
gcggacaggcagaagcccgcgggccgtgcggtccctgccaggcaggtggtcgggcaccgg
cacagggcggggggcgcaggccggagctgggagcaggcccggggcgcgagcaggagccgg
actgggctggagctgcccctccgccggcccccgagcgcccacacagacggggatggctcc
cacgcgggccgggcgcgtggggacggcgccctgcagtcgctgtgtctcacgacgcccacc
gaggaggccgtctactgcttctacggcgacgactcggacgaggagccgtccagggcggcg
gccaccccgcggcggccgtccgccatcccccgggcggtgaagagggagcgtccagcgggc
aggaaggaggcgcaggccgtgcccaagcctgtgcccaagcctgcgccgcccgcccgggcc
cagcccagcctcatcgccgacgagacgccgccgcgctgctccctgagttcgtccgcgagc
tccctgggcgagcccgagcccccagcgccagcagcgagccggccccgagcccgcgaggtg
gccgtcaccaaggaccccggcccgggcggcgggctcgccggctcccccagcccgagggcc
caggcggagctgctgcggcgcggcatcggctcagccctgcccaggcgccgaccccaggca
ccagccccgcggcgacgcaagccccaagccgcccagccggacgagcggccggcagacggg
gcccaggagcgcggcgaggaggcagcgggctcagatcacgcctcagacctggacagcgtc
gagtggcgcgccatccaggagggcgccaactccatcgtcacgtggctgcaccaggcggca
gcggcagcggccaccagcgaggcctcgtctgagtctgactccatcctgtccttcatgtcg
gggctctcagtgggctccaccctgcagccctccccgcacaggaaggggccccggccacgg
gcggaaggccaggccggcagtggggtgcggccagagaaacgggatgcggccctggcccag
cgcggcagcgggccccgctcatcctgcggcccggagaagccacgaggcgctcagaagact
gtgtctggggtgccggctgtgctccggggccggacggtgatctacgtgcccagcccagcc
ccccgggcccccccaaaggccgctcccagcccccgtgctgcacccaggaagatgggaccc
cccagccccgcgcagccggcagcccccaccaaagcccccgggctggggcagccgcggtct
cggagcctgcaccggccgggcaagatctcggaactggtggcgctgagcccgccgcagagg
agcgccacaccacccgcacgcctcgccaagaccccctcgtccagctcctcccagacctcc
cctgcctcccagcccctgcccaggaggtcaccccccgccacccaggctacggggcccctg
cccggccccgggtcctcagcactgcccaagacgccggcgcgggccctgctggccaagcag
cacaagacgcagaagtcgcccgtgcgcatcccattcatgcagaggcccgcccggcggggg
ccgccgcccctggccagggcagcgctggagccgggccccaggggccgggcaggggccgaa
ggggggccgggcgcccgagggggccgcctgggcctggtgcgcgtggcctcggcccgctcc
agcggcagcgagtcctccgaccgctcgggcttccggcggcagctgacgttcatcaaggag
tcgccgggcctgccgcgccgccgccgcgcagaaccagccacctccgcctccacctccgcc
accatccccgcctcccagggcggctcgccccgccgcggccggcccgcgctgcccgccgtc
ttcctctgctcctcgcgctgcgacgagctgcgggcagccccgaggcaggccccgggcccc
catcggctccctgcagcccggcccggccccggagagcgaccgccgcggcgcaccagctcc
gagagcccgtcgcgcctgcccgtgcgcacgccggccgcccggcccgagacggtcaagcgc
tacgcctcgctgccacacatcagcatggcccgcaggcccgacggcgcggcccccgcaccc
acggccgacgccacccgccgcagcagcgacggcgaggcccggccactgcccagggtggcc
gcaccaggcaccacatggcgtcgcatccgggacgaggacgtcccgcacatcctgcggagc
acgctgcccgccactgccctgccgctgaggggcgcctcacccgaggagggcccgggcggc
cccccgcagcgcaagaccagcgacgccgtggtccagacggaggacttcgtggccaccaag
accaactccagcacgtccccgagcctggagagcagggagcccccccaggttccggccagc
ggccccatctccctgctcggcagcgacgtggacgggcccacccctgccaaggcgcccgcc
gccgccaccttcgtccacgagggcctggtggtggccgcagggggcttccccgccagccgg
cacggctcccccagccgctcggcccgcgtgccgcccttcaactacgtgcccagccccatg
gtggtggcccccactgactcggccgtggagaaggcaccggccgccgcccccgccagcctc
ctggaatag

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   RefSeq(pep) (6)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (19)   
   Pfam (19)   
All databases (35)   

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