KEGG   Equus przewalskii (Przewalski's horse): 103559491
Entry
103559491         CDS       T04644                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
epz  Equus przewalskii (Przewalski's horse)
Pathway
epz01522  Endocrine resistance
epz04010  MAPK signaling pathway
epz04015  Rap1 signaling pathway
epz04068  FoxO signaling pathway
epz04071  Sphingolipid signaling pathway
epz04114  Oocyte meiosis
epz04148  Efferocytosis
epz04218  Cellular senescence
epz04261  Adrenergic signaling in cardiomyocytes
epz04370  VEGF signaling pathway
epz04380  Osteoclast differentiation
epz04517  IgSF CAM signaling
epz04519  Cadherin signaling
epz04550  Signaling pathways regulating pluripotency of stem cells
epz04611  Platelet activation
epz04613  Neutrophil extracellular trap formation
epz04620  Toll-like receptor signaling pathway
epz04621  NOD-like receptor signaling pathway
epz04622  RIG-I-like receptor signaling pathway
epz04625  C-type lectin receptor signaling pathway
epz04657  IL-17 signaling pathway
epz04658  Th1 and Th2 cell differentiation
epz04659  Th17 cell differentiation
epz04660  T cell receptor signaling pathway
epz04664  Fc epsilon RI signaling pathway
epz04668  TNF signaling pathway
epz04670  Leukocyte transendothelial migration
epz04714  Thermogenesis
epz04722  Neurotrophin signaling pathway
epz04723  Retrograde endocannabinoid signaling
epz04728  Dopaminergic synapse
epz04750  Inflammatory mediator regulation of TRP channels
epz04912  GnRH signaling pathway
epz04914  Progesterone-mediated oocyte maturation
epz04917  Prolactin signaling pathway
epz04926  Relaxin signaling pathway
epz04932  Non-alcoholic fatty liver disease
epz04933  AGE-RAGE signaling pathway in diabetic complications
epz04935  Growth hormone synthesis, secretion and action
epz04936  Alcoholic liver disease
epz05014  Amyotrophic lateral sclerosis
epz05020  Prion disease
epz05022  Pathways of neurodegeneration - multiple diseases
epz05132  Salmonella infection
epz05133  Pertussis
epz05135  Yersinia infection
epz05140  Leishmaniasis
epz05142  Chagas disease
epz05145  Toxoplasmosis
epz05152  Tuberculosis
epz05161  Hepatitis B
epz05163  Human cytomegalovirus infection
epz05167  Kaposi sarcoma-associated herpesvirus infection
epz05169  Epstein-Barr virus infection
epz05170  Human immunodeficiency virus 1 infection
epz05171  Coronavirus disease
epz05205  Proteoglycans in cancer
epz05208  Chemical carcinogenesis - reactive oxygen species
epz05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
epz05415  Diabetic cardiomyopathy
epz05417  Lipid and atherosclerosis
epz05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:epz00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103559491 (MAPK11)
   04015 Rap1 signaling pathway
    103559491 (MAPK11)
   04370 VEGF signaling pathway
    103559491 (MAPK11)
   04668 TNF signaling pathway
    103559491 (MAPK11)
   04068 FoxO signaling pathway
    103559491 (MAPK11)
   04071 Sphingolipid signaling pathway
    103559491 (MAPK11)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    103559491 (MAPK11)
   04519 Cadherin signaling
    103559491 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    103559491 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    103559491 (MAPK11)
   04218 Cellular senescence
    103559491 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    103559491 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103559491 (MAPK11)
   04613 Neutrophil extracellular trap formation
    103559491 (MAPK11)
   04620 Toll-like receptor signaling pathway
    103559491 (MAPK11)
   04621 NOD-like receptor signaling pathway
    103559491 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    103559491 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    103559491 (MAPK11)
   04660 T cell receptor signaling pathway
    103559491 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    103559491 (MAPK11)
   04659 Th17 cell differentiation
    103559491 (MAPK11)
   04657 IL-17 signaling pathway
    103559491 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    103559491 (MAPK11)
   04670 Leukocyte transendothelial migration
    103559491 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103559491 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    103559491 (MAPK11)
   04917 Prolactin signaling pathway
    103559491 (MAPK11)
   04926 Relaxin signaling pathway
    103559491 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    103559491 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103559491 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    103559491 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    103559491 (MAPK11)
   04722 Neurotrophin signaling pathway
    103559491 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103559491 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103559491 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    103559491 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103559491 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    103559491 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103559491 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103559491 (MAPK11)
   05161 Hepatitis B
    103559491 (MAPK11)
   05171 Coronavirus disease
    103559491 (MAPK11)
   05163 Human cytomegalovirus infection
    103559491 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103559491 (MAPK11)
   05169 Epstein-Barr virus infection
    103559491 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103559491 (MAPK11)
   05135 Yersinia infection
    103559491 (MAPK11)
   05133 Pertussis
    103559491 (MAPK11)
   05152 Tuberculosis
    103559491 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103559491 (MAPK11)
   05140 Leishmaniasis
    103559491 (MAPK11)
   05142 Chagas disease
    103559491 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103559491 (MAPK11)
   05020 Prion disease
    103559491 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    103559491 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103559491 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    103559491 (MAPK11)
   05415 Diabetic cardiomyopathy
    103559491 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103559491 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    103559491 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103559491 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103559491 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:epz01001]
    103559491 (MAPK11)
Enzymes [BR:epz01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     103559491 (MAPK11)
Protein kinases [BR:epz01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   103559491 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH RIO1 Cas_CT1975 FTA2
Other DBs
NCBI-GeneID: 103559491
NCBI-ProteinID: XP_070455347
UniProt: A0ABM4MRN5
Position
29:complement(46377808..46385165)
AA seq 364 aa
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLVHARRTYRELRLLKHLKHENVIGLLDVFTPATSIDDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLIYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLRSIFHGANPLAVDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPDDEPEAEPYDESVEAKERTVEEWKELTYQEVLSFEPPEPPQPPSSL
ETGQ
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgtcgggcccgcgcgccggcttctaccggcaggagctgaacaagacggtgtgggaggtg
ccgcagcggctgcaggggcttcgcccggtgggctccggcgcctacggctccgtctgctcg
gcctacgacgcgcggctgcgccagaaggtggcagtgaagaagctgtcgcggcccttccag
tctctggtccacgcgcggaggacttaccgcgagctgcggctgctcaaacacctgaagcac
gagaacgtcatcgggctgctggacgtcttcacgccagccacttccatcgatgacttcagc
gaagtgtacctggtcaccaccctgatgggcgccgacctgaacaacatcgttaagtgccag
gcgctgagcgacgagcacgtccagttcctcatctaccagctgcttcgagggctgaagtac
atccactccgctgggatcatccaccgggacctgaagcccagcaatgtggcggtgaatgag
gactgcgagcttaggatcctggactttgggctagcacgccaggctgacgaggagatgacc
ggctacgtggccactcgctggtaccgcgcacctgagatcatgctcaactggatgcactac
aaccagacagtggacatctggtctgtgggctgcatcatggccgagctgctccagggaaag
gccctcttcccaggaaatgactacatcgaccagctgaagcgcatcatggaggtggtgggc
acacccagccctgaggttctggcaaagatatcctcagaacatgcccggacatacatccag
tccctgccccccatgccccagaaggacctcaggagcatcttccacggagccaaccctctg
gctgtggacctcctgggaaggatgctggtgctggacagtgaccagagggtcagtgcagcc
gaggccctggcccatgcctatttcagccagtaccacgacccggacgacgagcctgaggcc
gagccctatgacgaaagcgttgaggccaaggagcgcacagtggaggagtggaaggagctc
acctaccaggaagtcctgagcttcgagcccccagagccaccgcagccacccagcagtctg
gagactgggcagtga

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