KEGG   Echinops telfairi (small Madagascar hedgehog): 101649302
Entry
101649302         CDS       T08707                                 
Symbol
ATM
Name
(RefSeq) serine-protein kinase ATM
  KO
K04728  serine-protein kinase ATM [EC:2.7.11.1]
Organism
etf  Echinops telfairi (small Madagascar hedgehog)
Pathway
etf01524  Platinum drug resistance
etf03440  Homologous recombination
etf04064  NF-kappa B signaling pathway
etf04068  FoxO signaling pathway
etf04110  Cell cycle
etf04115  p53 signaling pathway
etf04210  Apoptosis
etf04218  Cellular senescence
etf05165  Human papillomavirus infection
etf05166  Human T-cell leukemia virus 1 infection
etf05170  Human immunodeficiency virus 1 infection
etf05202  Transcriptional misregulation in cancer
etf05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:etf00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    101649302 (ATM)
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    101649302 (ATM)
   04068 FoxO signaling pathway
    101649302 (ATM)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    101649302 (ATM)
   04210 Apoptosis
    101649302 (ATM)
   04115 p53 signaling pathway
    101649302 (ATM)
   04218 Cellular senescence
    101649302 (ATM)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    101649302 (ATM)
   05206 MicroRNAs in cancer
    101649302 (ATM)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101649302 (ATM)
   05170 Human immunodeficiency virus 1 infection
    101649302 (ATM)
   05165 Human papillomavirus infection
    101649302 (ATM)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101649302 (ATM)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:etf01001]
    101649302 (ATM)
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:etf03032]
    101649302 (ATM)
   03036 Chromosome and associated proteins [BR:etf03036]
    101649302 (ATM)
   03400 DNA repair and recombination proteins [BR:etf03400]
    101649302 (ATM)
Enzymes [BR:etf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     101649302 (ATM)
Protein kinases [BR:etf01001]
 Serine/threonine kinases: Other
  PIKK family [OT]
   101649302 (ATM)
DNA replication proteins [BR:etf03032]
 Eukaryotic type
  DNA Replication Termination Factors
   Other termination factors
    101649302 (ATM)
Chromosome and associated proteins [BR:etf03036]
 Eukaryotic type
  Meiosis-specific proteins
   DSB formation-related proteins
    101649302 (ATM)
DNA repair and recombination proteins [BR:etf03400]
 Eukaryotic type
  Check point factors
   Other check point factors
    101649302 (ATM)
SSDB
Motif
Pfam: PI3_PI4_kinase FAT FATC M-HEAT_ATR
Other DBs
NCBI-GeneID: 101649302
NCBI-ProteinID: XP_045153674
Position
Unknown
AA seq 2710 aa
MLHILNRLQDVFNENTQFLEISQSYTTTQREFSDCSTPCKRRRIESGWEVIKDHLQKSQN
DFHLVPWLQITTQLISKYPTSLPNCELTPLLIILSQLLPQQRRGERTPYVLRCLMEVALC
QGKTLNLESSQKSDLLKLWMKICSITFRGISSEQIQVENFGLLGAIIKGNLVEVDREFWQ
LFTGSACKPSGPAVCCLAVALTIAVIPERVTAGREQHLCEVNRSFSLRERIMKWLLFYQL
EDDLEDLTELPPVLLSKFPHLSVEKILVSLTLKNCKAAMIFFQSVPECEQHQKDKEESSF
SQVEELFLQTTFDKMDFLTVVKECATEKHRSSPGFSVHQSLKEALDHYLLALSEQLLSNY
SPETADSDALVRCSSVLVGVLGCYCYVGVIAEEEAHKSELFQKAKSLMQCAGESITLFKN
KTNEDPRIDSLRNMMLLCISCLCNCTKHSPNKIASGFFLRLLTSKFMNDIADICKILSSF
IKKPFDSGEVETVEDDPDESGMEVENQSPLNLFGDYSTCPVSDANESGESQSNTGAMNPL
AEEYLSKQDLLFLDMLKFLCMCVTTAQTNTVSFRAADIRRKLLMLIDSSTLDLTKSLHLH
MYLVLIKELPGEDTPLPIEDVVELLKPLSNVCSLYRRDQEVCKTILNHILHIVTNLGQGH
VDNEHTRDAQGQFLTVMGAFWHLAKEGKCTASVRMALVRCLKALLEADPYSKWAILNVMG
KDFPVNEVFPQFLADNHHQVRMLAAGSINRLFQDMKQRESSKLLKALPLTRQRTAFQNAY
QQARDGMRESRNAENLELSDELHNRKAVLLMMVAVVLHCSPVCEKQALFALCKSVKENGL
EPLLIKKVLEKVSEIFGYRHLEDFMTSHLDYLILEWLNQQETERTLSSFPFILLNYTCVE
DFYRSCYKALIPHLVIRSHFDEVKSIANQIQEDWKVLLTDCFPKVLVNILPYFAYESTGD
SEMSQQRETAVNVYDMLKDESLLGKQIDHLFISNLPEIVFELLMTLHEPAKSDGTQNTDL
CGFSGDLDPAPNPPYFPSHVIKATFAYISNCHKTKFKSILEILSKSPDSYQKILLAICEQ
AAETNNVYKKKRILKIYHLFVSLLLKEIKSGLGGAWAFVLRDVIYTLIHYINKRPSHFMD
VSLRTFSLCCDLLSRVCQTAVAFCKDALESHLHVIVGTLIPLVNGQLEVQEQVLDLLKYL
VIDNKDNENLYLTIKLLDPFPDHVVFKDLRITQQKIKYSRGPFLLLEEINHFLSVSVYDA
LPLTRLEGLKELRRQLEQHKDQIKGLTRASQENPQDGILVKLVVSLLQLSKMAVNHPGER
EVLEAVGSCLGELGPIDFSTIAIQHSKDASYNKALELFEDKELQWIFILLTHLNNTLVED
CVKVRSAAATCLKSILATKTGHNFWEVYKTTTDPMLAYLQPFRASRKKFLEVPRLDRRSP
FEDLDETSLWIPQNGNHDVWIKTLTCAFLDSGGIKSEVLQLLKPMCEVESDFCQTVLPYL
IHDILLQDTSECWRNLLSVHIQGFFSSSFRQSSQTSRSTTPANLDSDSEHFVRGGLDKKS
QRTMLAVVDYMRRQKRPLSGTVYDDAFWLDLNYLEVAKVAQSCAAHFTALLYAEIYADQK
NMGDQEKRSPTLEEGSQSTTISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGK
VLQPLTRIRTYEHEAMWGKALITYDLETAISSSTRQAGIIQALQNLGLCHILSTYLRGLD
HENKESCAELQELHYQAAWRNMQWDHCSSVNKGIEGTSYHESLYSALQSLRDREFSTFYE
SLKHARVKEVEELCKGSLESVYSLYPTLSRLQAIGELENIGELFSRSLAERQLSEVYGKW
QKHSQLLKDSDFRFQEPIMALRTVVLELLTEKAMESAQRQCFKDILTKHLVQLSTLARTF
QNTQLPERAIFQIKQYNSTSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLGDSCTE
EPTLKLLYTECLRVCGNWLAETCLESPSVIMQTYLEKAVEVVGNYDGGSSDELRNGKTKA
FLSLARFSDTQYQRIENYMKSSEFENKQALLRKAKEEVGLLREHKIQTNRYTVKVQRELE
LDECALRALKEDRKRFLYKAIENYINCLLSGEEHDMWVFRLCSLWLENAGASEVNGMMKR
VGMKIPSHKCLPLMYQLAARMGTKMMGGLGFHEVLDNLISRISMDHPHHTLFIILALANA
NKDEFLTKPEAAKRSRITKTTPKQNSQLDEDRAAAARKIIHVIKSRRPQMVRNVEALCDA
YILLANLDATQWKMQRKGINIPTDQPITKLKNLEDVVVPTMEIKVDPTGKYESLVTIQSF
RAEFRLAGGINLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETR
KRKLTICTYKVVPLSQRSGVLEWCTGTVPIGDFLVHSEDGAHKRYRPQDLSAYQCQKKMM
DVQKKSFEEKYETFMDICQNFQPVFRYFCMEKFLDPAVWFEKRLAYTRSVATSSIVGYIL
GLGDRHVQNILINEQSAKLVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGV
FRRCCEKTMEVMRSSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELNSTLNT
VDQECKQNLSGIDQSFNKVAERVLMRLQAKLKGVEEGTVLSVGGQVNLLIQQAMDPKNLS
RLFPGWKAWV
NT seq 8133 nt   +upstreamnt  +downstreamnt
atgttgcacatactgaatagactacaggatgtttttaatgaaaatacccaatttctggag
atttctcagtcttatactactacacaaagagaatttagtgactgcagtacaccttgcaaa
aggaggagaatcgaatctggctgggaagtaattaaagatcatcttcagaaatcacagaat
gattttcatcttgtgccttggttacagattacaacacaattaatatcaaagtaccctaca
agtttgcctaactgtgagctaacaccattactgataatactctcccagcttctacctcaa
caacgacgtggggaacgcacaccatacgtgttacgatgccttatggaagttgctctgtgt
caaggcaagactttaaacctcgaaagctctcaaaagtcagatcttctgaagctctggatg
aaaatttgttctattacctttcgaggtataagttctgaacaaatacaagttgaaaacttt
ggcttacttggagccataattaaaggcaatctagttgaagttgatagagagttttggcag
ttatttactgggtcagcctgcaaaccttcaggccctgcagtatgctgcttggcagtggca
ctcaccatagctgtaattcctgaaagagtaacagcaggccgagagcagcatctctgtgaa
gtgaatagaagtttttcattaagagaaaggatcatgaaatggctcttattctatcagtta
gaggatgacttagaagaccttaccgagctgccccccgttcttctcagtaagtttcctcac
ctttcagtggagaaaattcttgtgagtctcactctgaaaaactgtaaagctgcaatgatt
tttttccaaagtgtcccagaatgtgagcaacaccaaaaagataaagaagaatcctcattt
tcacaagtagaagaactgtttcttcagacaacttttgacaagatggattttttaaccgtt
gtgaaagaatgtgctacagaaaagcaccgatccagtcctggattttctgtccaccagagt
ctcaaggaagcactggatcactatcttctagcattatcagaacagctgctatctaattac
tcacccgagactgcagattcagacgcgcttgtccggtgttccagtgttttggtgggtgtc
cttggctgctattgttacgtgggtgtaatagctgaagaggaagcacataagtcagaatta
ttccaaaaagccaagtccctaatgcagtgtgcaggggaaagtatcactctgtttaaaaat
aagacaaatgaagaccctagaattgactcgttaagaaacatgatgcttctgtgtataagc
tgcttatgcaactgtaccaagcacagtccaaataagattgcatctggcttttttctgaga
ttgttaacatcaaagttcatgaatgacattgcagatatttgtaaaattttatcatccttt
atcaaaaagccatttgattctggagaagtagagacagtggaagatgatcctgatgaaagt
ggaatggaagtggagaatcagtcacctctgaatctgtttggcgactactctacttgtcct
gttagtgatgcaaatgaatctggagagagccaaagtaatactggtgctatgaacccttta
gcagaagaatatttgtcaaagcaagatctactgtttttagacatgctcaagttcttgtgt
atgtgtgtaactactgcccagaccaacacagtgtcatttagagcagctgatattcggagg
aaactgttaatgttaatagattctagcacactagatcttacaaaatctcttcacctacac
atgtatttagtacttataaaggagctcccaggagaagacactcccttgccaattgaagat
gttgttgagcttctgaaacctctatctaatgtgtgttctttgtatcgccgtgaccaagaa
gtttgcaaaaccattttaaaccacatccttcatatagtaacaaacctgggacaaggccat
gtggacaatgagcacaccagggatgctcaagggcagttcctaacagtgatgggagcattt
tggcacttagccaaggagggaaaatgcacagcatctgtgagaatggcactagtaagatgc
cttaaggctctgcttgaggctgatccttattcaaaatgggcgattctcaatgtaatggga
aaagacttccctgtaaatgaagtattcccacaatttcttgctgataatcatcaccaagta
cgaatgttggctgcagggtcaatcaacagattattccaggatatgaagcagagagagtct
tccaagttattgaaagcccttcctctgacgcgtcaacggacagcgtttcaaaatgcatac
cagcaagcccgggacgggatgagagagtcccgcaatgccgagaacctggaactttcagat
gagcttcataatagaaaagctgtcttactgatgatggtagctgtggttttacactgtagc
cccgtctgtgagaaacaagccttgtttgctctctgcaaatctgtgaaagagaatggatta
gagcctctcctcattaaaaaggttttagagaaagtgtctgaaatttttggctatagacac
ctggaagatttcatgacttctcacttagattatctaattttggagtggctcaatcaacaa
gaaactgaacgcaccttatcttctttcccttttattttactaaactacacatgtgttgag
gatttctacagatcttgctataaggctttgatcccacatctggtgattagaagccatttt
gatgaggtcaagtccattgcgaatcagattcaagaggactggaaagttcttctaacagac
tgcttcccaaaggttcttgtgaatatccttccatattttgcctatgagagtacaggagac
agtgagatgtcacagcaacgagagactgctgtcaatgtgtatgacatgctcaaagatgag
agcttgttagggaaacagattgatcatttattcattagtaatttaccagagattgtgttc
gaattattgatgacattacatgaaccagcaaaatctgatggcacccaaaacactgacctc
tgtggcttttcaggggatttggatcctgctcctaatccaccttattttccatcgcatgta
attaaggcaacatttgcctatatcagcaattgccataaaaccaagtttaagagcatctta
gaaattctttccaaaagccctgattcctatcaaaaaattcttttagctatatgtgaacaa
gcagctgagacaaataatgtatataaaaagaagagaattcttaaaatatatcacctgttt
gttagtttattactgaaggagataaaaagtggcttaggaggagcttgggcctttgttctt
cgagatgttatttatactttgatccactatatcaacaaaaggccctctcacttcatggat
gtgtccttacgcaccttctccctttgttgtgacctcttaagtcgggtttgccagaccgca
gtggcgttctgcaaggatgctttagaaagccatctccatgttatcgttggtactcttatc
cccctggttaatggtcaattggaagttcaggaacaggtcttggacttgttaaaataccta
gtgatagataacaaggataatgaaaacctgtatctcacaattaagcttttagatcctttt
cctgaccacgttgtttttaaggatttgcgtattacgcagcagaaaatcaaatatagtaga
ggaccatttttactcttggaggaaattaatcatttcctctcagtgagtgtttatgatgcg
ctacctttgacaagactcgaaggactgaaggagctccgaaggcagctggagcagcataaa
gatcaaatcaagggtctcacgagagcttctcaggaaaacccacaagatggcattctggtg
aagctggtggtgagcttgttgcagttatccaaaatggcggtaaaccaccctggggaaaga
gaagttttagaggctgttggaagctgcttgggagagttgggccctatcgatttctccacc
atagccatacaacatagtaaagatgcatcttataataaggcccttgagttatttgaagat
aaagaacttcagtggattttcatactgctgacccacctgaataataccctagtagaagat
tgtgtcaaagttcgatcagctgctgctacctgtttgaaaagcattttagccacgaagact
ggacataatttctgggaggtatacaagacaacgactgatcccatgctcgcctatctgcag
cctttcagagcatcaagaaaaaagtttttagaagtacccagactggacagaagaagtcct
ttcgaagacctggatgagacaagtttgtggattcctcaaaacggaaatcatgatgtttgg
ataaaaacactgacttgtgcttttttggacagtggaggcataaaaagtgaagttcttcag
ttgctaaagcccatgtgtgaagtggaaagtgacttttgtcagactgtgctaccgtacttg
attcatgatattttgctgcaagatacaagtgagtgctggaggaatctgctgtctgtgcat
attcagggattcttcagcagttctttcagacagtcctcacaaaccagcaggtccaccacc
ccggcaaacttggattcggactcagaacactttgtccgaggcggtttggataagaaatca
caaagaactatgcttgctgttgtggactacatgagaagacagaagcgacctctctcagga
accgtttacgatgatgctttctggctggatttgaactatctagaagttgccaaagtggct
cagtcttgtgcggctcactttacagcattgctttatgcagaaatctatgccgatcagaaa
aacatgggtgatcaagagaaaaggagccctacattggaagaaggaagccaaagtacaact
atttctagtttgagtgaaaagagtaaagaagaaactggaataagtttacaggatcttctc
ctagagatctacagaagcataggagagccagatagcctgtatggttgtggtggaggaaaa
gtgttacaaccactcactcgaatacgaacatatgaacatgaggcaatgtggggtaaagct
ctgataacatatgaccttgagacagcaattagctcatccactcgccaggccggaattatt
caggccctgcagaatctgggactctgccacattctctccacctacttaagaggattagat
catgaaaataaagagtcgtgtgctgagcttcaggaactgcattaccaagctgcgtggagg
aacatgcagtgggaccactgcagttcggtcaacaaaggaattgaaggaaccagctaccac
gaatccttgtacagcgctctgcagtctctaagagacagagagttttccaccttttatgaa
agtctgaaacatgccagagtgaaagaagtggaagaattgtgtaagggcagccttgagtct
gtatattcactctacccaactctaagcagattgcaggccatcggtgagctggagaacatt
ggagagcttttctcaaggtcactcgccgagcggcagctctcggaagtgtacggtaagtgg
cagaagcactcgcagctcctgaaggacagtgattttcgcttccaggagcccatcatggct
ctgcgcacagtcgttttggagctcctgacggaaaaggcaatggagagcgcccagaggcag
tgttttaaagacatcctcaccaagcaccttgtacagctgtccacactggcccgaacattc
cagaatacccagctccctgaaagggctatatttcaaattaagcagtataattcaacaagt
tgtggagtctctgagtggcagttggaggaagcgcaagtattctgggcgaagaaggaacag
agtcttgctctgagtattctcaagcaaatgatcaagaaattgggtgacagttgtacagag
gaacccaccctcaaactgctgtacacggaatgcttgagggtttgtggcaactggttagca
gaaacttgcttagaaagcccctcagtcatcatgcagacctatctggaaaaggcagtggaa
gttgttggaaattacgatggaggaagcagtgatgagctgagaaatggaaaaacaaaggcg
tttctctcgttagcacggttctcagatactcagtaccagagaattgaaaactatatgaag
tcatccgaatttgaaaacaaacaagctcttctgaggaaggctaaagaggaagtgggcctc
ctcagggaacataaaattcagaccaacaggtacacagtcaaggttcagcgagagctcgag
ctggatgaatgtgcactccgggctctgaaggaagatcgtaagcgcttcttatataaagcg
attgaaaattacatcaactgcttattaagtggagaagagcatgacatgtgggtgttccga
ctctgttctctctggctggaaaatgctggcgcttctgaagtcaatggcatgatgaagcgc
gttggaatgaagattccgtcacataaatgtttgcctcttatgtaccagttggctgctaga
atggggaccaagatgatgggaggcctagggtttcatgaggtcctcgacaatctcatctcc
agaatttcaatggatcatccccatcatactttatttattatactggccttagcaaatgcc
aataaagatgaatttctgaccaaaccagaggcagcaaaaaggagtagaataaccaaaacc
acacccaaacaaaactctcagcttgatgaggatagagctgcagctgcacgtaaaataata
catgttatcaaaagtaggagaccccagatggtcaggaatgttgaggcactttgtgacgct
tatattctgttagcaaacttagatgccactcagtggaagatgcagagaaaaggcataaat
attccaacagaccagccaattactaaattgaagaatttagaagatgttgttgtccccact
atggaaatcaaggtggaccccacaggaaaatatgagagtctggtgacgatacagtcattc
agagcagaatttcgtttagcaggaggtataaatttgccaaaaataatagattgtgtaggc
tctgatggcaaggaaaggcgacagcttgtcaagggccgcgatgacctgcgacaagatgct
gtcatgcagcaggttttccagatgtgtaatacattactgcagagaaacacggaaaccaga
aagaggaaactaaccatctgcacatataaggtggtccccctgtctcagcgaagtggggtt
ctggagtggtgcacagggaccgtgcccattggcgactttctggttcacagtgaagacggt
gctcataaaagatacaggccccaggatctcagtgcgtaccagtgccaaaagaaaatgatg
gatgtgcaaaagaaatcttttgaggagaagtatgaaactttcatggatatctgccaaaat
tttcagcccgttttccgttacttctgcatggaaaagttcttggatccagctgtttggttt
gagaaacgattggcttatactcgcagtgtggctacttcttcgatcgttggttatatactt
ggacttggtgatagacatgtacaaaatatcttgataaatgaacagtcagcaaaacttgta
catattgatctcggggttgcgtttgaacagggtaaaattcttcctactcctgaaacggtt
cctttcagactcaccagagatattgtggacgggatgggcatcactggggtggaaggcgtc
ttcagaaggtgctgtgagaaaacgatggaagtcatgaggagctctcaggaaaccctcctg
accattgtagaggtcctcctctatgatcctctctttgactggaccatgaatccattgaaa
gctttgtatttacagcagaggcccgaagatgaaaccgagctcaactccactctgaataca
gttgaccaagaatgcaaacaaaatctcagtggcatcgaccagagtttcaacaaagtagct
gaacgtgtcttgatgagactccaagcgaagctgaaaggcgtggaggagggcactgtgctc
agcgtggggggacaggtgaacctgctcattcagcaggccatggaccccaaaaatctcagc
cggcttttcccaggatggaaagcatgggtgtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (8)   

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