KEGG   Echinops telfairi (small Madagascar hedgehog): 101663717
Entry
101663717         CDS       T08707                                 
Symbol
TSC2
Name
(RefSeq) tuberin isoform X1
  KO
K07207  tuberous sclerosis 2
Organism
etf  Echinops telfairi (small Madagascar hedgehog)
Pathway
etf04072  Phospholipase D signaling pathway
etf04115  p53 signaling pathway
etf04140  Autophagy - animal
etf04150  mTOR signaling pathway
etf04151  PI3K-Akt signaling pathway
etf04152  AMPK signaling pathway
etf04211  Longevity regulating pathway
etf04218  Cellular senescence
etf04714  Thermogenesis
etf04910  Insulin signaling pathway
etf04919  Thyroid hormone signaling pathway
etf05163  Human cytomegalovirus infection
etf05165  Human papillomavirus infection
etf05168  Herpes simplex virus 1 infection
etf05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:etf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    101663717 (TSC2)
   04151 PI3K-Akt signaling pathway
    101663717 (TSC2)
   04152 AMPK signaling pathway
    101663717 (TSC2)
   04150 mTOR signaling pathway
    101663717 (TSC2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101663717 (TSC2)
  09143 Cell growth and death
   04115 p53 signaling pathway
    101663717 (TSC2)
   04218 Cellular senescence
    101663717 (TSC2)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    101663717 (TSC2)
   04919 Thyroid hormone signaling pathway
    101663717 (TSC2)
  09149 Aging
   04211 Longevity regulating pathway
    101663717 (TSC2)
  09159 Environmental adaptation
   04714 Thermogenesis
    101663717 (TSC2)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    101663717 (TSC2)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    101663717 (TSC2)
   05163 Human cytomegalovirus infection
    101663717 (TSC2)
   05165 Human papillomavirus infection
    101663717 (TSC2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:etf01009]
    101663717 (TSC2)
Protein phosphatases and associated proteins [BR:etf01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     101663717 (TSC2)
SSDB
Motif
Pfam: Tuberin DUF3384 Rap_GAP Cnd1 HEAT
Other DBs
NCBI-GeneID: 101663717
NCBI-ProteinID: XP_045142047
Position
Unknown
AA seq 1820 aa
MAKPTSKDSGLKEKFKTLLGLGPSRPHARSTEGKHTEFVITAEILRELSVEYGLSNRIRV
IGQICEVARTKRFEEHAVEALWRAVADLLQPDRPPEARHAVLALLTAIVQGQGDRLGVLR
ALFFRVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL
VNLVKFNSCYLDEYIASMVQMICLLCIRTTSPVDIEVSLQVLDAVVCYNCLPAESLPLFI
VTLCRTVNVKELCEPCWKLMRNLLGTHLGHSAIYHMCRIMEDRAYMEDAPLLRGAVFFVG
MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSVSRLIKKYRKELQAVTWDV
LLTIIERLLQQLQTLESSGLRAPVHDLLTTVEELCDQNEFHGPRDRFFELVERHAEQRPE
ASILNLISYRAQSIHPAKDGWVHHLQRLMERFFRSESRSAVRIKVLAVLSFVLLINRQFY
EEELINSVVLCQLSSIPEDKDPQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARPLS
PPPELEERDWPAHSASLEEVKTAVLGLLVILQTKLYTLPASHAARVYETLVHHLQLHYKH
AYSLPIASSIRLQAFDFLLLLRADSLHRLGLPSKDGAVRFSPYCLCDYKEPERSTEKKAS
GPLSPPTGPPGPAPPGPAVRLAYLPYSLLFRVLLQCLKQESDWKVLKLVLSKLPASLRHK
VLVSTSPCSVDQLSAALCSMLSGPKTLERLRGTPEGFSRTDLHLAVVPVLTALSSYHGYL
DKARQREMVYCLEQGLIYRCASQCVVALAVCSVEMPAVITKALPVLIVKLTHISATASMA
APLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC
RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPRRGSSGRRDPPGSVRP
ARSPKQGSSHSRPVRERPESSAAEAFRCRSVSVSEQVVRSRIQSSLTSTSLGSADENSVA
QADGSLRTLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLITV
TTSVGTGTRSLLGLEPGELQAGPERSTDPSLLVRQTKEAPAKLESQAGAQVCRGARDRVR
SMSGGHGLRVGALETPPTHSPGGPSASGLQTPPVTKPEKAPTGAQTPKEKASLAACVPLL
TQGWAEILVRRPTGNTSWLLSLENPLSPFSSDMDNMPLQELSNALMAAERFKEHRDTALY
KSLSVPSTSAAAATPSPLPRSNTVASLSSLSQSSCQGRLHRSVSWADSPAVLEEGRAAQE
NMSTESPELDDFEAAPGPDRRCRRARTYSRSSSTSSQEEKPLRVEERGASSSIPILRAGG
GPPCADLPFQPSQPLSKSSSSPELQTLQDVLGDAGHKADVGRLSPEAKARSQSGTLNGES
DPWPAPGEEGRACGPSQHESPPPAGSPRSPGGLRPRGYTISDSAPSRRGKRVERDSFRGR
AAAANAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKI
AVLYVGEGQSNSELAVLSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVGGEDGQ
FTYCWHDDIMQAVFHIATLMPTKDGDRHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQ
FNFVHVMITPLDYECNLVSLQCRRDMEGLVDTSVAKIVSDCNLPFVARQMALHANMASQV
HHSRSNPTDVYPSKWIARLRHIKRLRHRIREEAHCLNPSLPLVQTQPSAPTKTQAEPTPT
YETGQRKRLISSVDDFTEFV
NT seq 5463 nt   +upstreamnt  +downstreamnt
atggccaagcccaccagcaaagactcgggcttgaaggagaagttcaagacgctgctgggg
ttggggccctcacggccacatgccaggtccacagagggcaagcacacggagttcgtgatc
acagccgaaatcctgagagagctgagcgtggagtacgggctgagcaatcgcatccgagtc
atagggcagatctgcgaagtggcgagaaccaagaggtttgaggagcacgccgtggaagca
ctatggagggccgtcgctgacctgctgcagcccgacaggccgccagaggcccgccatgct
gtgctggccctgctcaccgccattgtgcagggccagggggaccgcctgggcgtgctgcga
gccctcttcttcagggtcatcaaggactacccctccaatgaagacctgcacgagcggctg
gaagtgttcaaggccctcacagacaacgggagacacatcacctacttggaagaagaattg
gctgactttgtcctgcagtggatggatgtcggcttatcctcagagttcctgctggtgctt
gtgaacctggtcaagttcaacagctgttacctggacgagtacatcgcatccatggttcag
atgatttgcctgctgtgcatccggaccacgtcacccgtggatatagaggtctccctgcaa
gtgctggacgccgtggtctgctacaactgcctgcctgccgagagcttgcccctgttcatt
gtcaccctctgccgcactgtcaacgtcaaggaactgtgtgagccctgctggaagctcatg
cggaacctgctggggacacacctgggccacagcgccatctaccacatgtgccgcatcatg
gaggaccgagcctacatggaagacgccccgctgctgagaggagccgtgttctttgtcggc
atggcgctctggggggcccaccggctctactccctgaagaactcccccacatctgtgctg
ccctccttctatgaggccatgacctgccccaacgaagtggtgtcctacgagatcgtgctg
tccgtgtcccgcctcatcaagaagtaccggaaggagctgcaggccgtgacctgggacgtg
ctgctgaccatcatcgagcggctgctccagcagctgcagaccctggagagctcgggcctc
cgggcgcccgtgcacgacctgctgaccaccgtggaggagctgtgtgaccagaacgagttc
catgggccacgggacaggttcttcgagcttgtcgagaggcacgctgagcagagaccggag
gcttccatcctgaacctgatctcgtaccgggctcagtccatccacccagccaaggacggc
tgggtccaccacctgcagcggctgatggagcgcttcttcaggagcgagtcccgcagcgcc
gtgcgcatcaaggtgctggctgtcctctccttcgtgctgctcatcaaccggcagttctac
gaggaggagctcatcaactcagtcgtgctctgccagctgtcctccatcccggaggacaag
gacccccaggtccgaaagctggctacccagttgctggtggacctggcagagggctgccac
acccaccacttcaacagcctgctggacatcattgagaaggtgatggcccgccccctgtcc
ccaccccctgagctggaggagagggactggcctgcccactcggcctccctggaggaggtg
aagaccgccgtcctggggctcctggtcatcctgcagaccaagctctacaccttgccggcc
agccacgcagcccgagtctacgagacactcgtgcaccacctacagctgcactacaagcac
gcttacagcctccccatcgccagcagcatccgactccaggcctttgacttcttgctgctg
ctgcgggcagactcactgcaccgcctgggcctgcccagcaaggacggcgctgtgcgcttc
agcccctactgcctgtgtgactacaaggagcctgagcgtagcactgagaagaaggccagc
ggccccctctcaccacccacgggacctccaggcccagctcccccgggcccggccgtgcgg
cttgcctacctgccctactctctgctcttccgcgtcctgctgcagtgcctgaaacaggag
agcgactggaaggtgctgaagctggtgctcagcaagctgccggcgtctctgcgccacaag
gtcctcgtctccacctccccgtgcagcgtcgaccagctgtcggccgccctctgctccatg
ctttcaggccccaagaccctggagcggctgcgcggcacccccgagggcttctccagaact
gacctgcacctcgccgtggtgcccgtgctgacggcactcagctcctaccacggctacctg
gacaaagccagacagcgcgagatggtgtactgcctagagcaaggcctcatctaccgctgc
gccagccagtgcgtggtggcgctggccgtgtgcagcgtggagatgcccgccgtcatcacc
aaggccctgcccgtgctcattgtcaagctcacccacatttcggccactgccagcatggct
gcccctctgctcgagttcctgtccactctggcgcggctgccgcatctctacaggaacttc
gcggcagagcagtatgccagcgtgtttgccatctccctgccatataccaacccgtccaag
ttcaatcagtatatcgtgtgcctggctcaccacgtcatagccatgtggttcatccggtgc
cgcctgcccttccggaaggactttgttccctacatcacgaagggcctccgctccaacgtg
ctcctctccttcgatgacacccccgagaaggacagtttccgagccaggagcaccagtctc
aacgagaggccccggaggggctcttcggggcggcgcgatccccctggtagtgtaaggcca
gccaggtcccccaaacaaggctcgagccactctcggcccgtgagagagcgcccggaaagc
agcgcagccgaggccttccgctgccgcagcgtcagtgtgtctgagcaggtggtccgcagc
aggatccagagctcgctcaccagcaccagcctgggttctgccgacgagaactctgtggcc
caggcggacggcagcctgcgcaccctccacctggagctcaccgagacgtgcctggacatg
atggccagatacgtcttctccaacttcaccgccgtgcccaagaggtcccccgtgggagag
ttccttctggctggaggccggaccaagacctggctggtagggaacaagctgatcaccgtg
acgaccagtgtgggcacaggcacgcggtcactgctgggcctcgagcctggcgagctgcag
gctggccccgagcgcagcactgaccccagcctgctcgtgcggcagaccaaggaggcgccg
gccaagctggagtcccaggcaggagcgcaggtgtgccgcggggcccgcgaccgcgtccga
tccatgtcagggggccatggcctgcgtgtgggggccctggagaccccacccacccactcc
ccaggaggccccagtgcctctgggctgcagaccccaccagtcactaagcctgagaaggcc
cccactggagcccagacgccaaaggaaaaggcgagcctggcagcctgcgtgcccctgctg
acccagggctgggccgagatcctggtccggaggcccacagggaacacgagctggctgctg
agcctggagaacccgctgagccccttctcctccgacatggacaacatgcccctgcaggag
ctgtccaatgccctcatggccgcagagcgcttcaaggagcaccgggacaccgccctgtac
aagtcgctgtcggtgccatccaccagtgccgctgccgccacgccctcccccctgccccgc
tccaacacagtggcctctctctcctccctgagccagtccagttgccaaggaaggctgcac
aggagtgtgtcctgggcagactccccggcagtcttggaggagggacgtgcagctcaggag
aacatgtccaccgagtcccccgagctggacgactttgaggcggcccctggtccagacagg
cgctgccgacgagctaggacctacagcaggtcatcgtccacctccagccaagaggagaag
ccgctgcgtgtggaagagcggggggccagcagcagcatccccatcttgagggctgggggt
ggcccaccctgcgcagacctccccttccagccctcgcagcccctgagcaagtccagctcc
tcccctgagctgcagacgctgcaggacgtcctcggggatgcaggtcacaaagccgacgtg
ggccgactgagcccggaggccaaggcccgctcacagtcagggaccctgaatggggagagc
gacccctggccagccccaggcgaggagggccgggcctgtggcccctcccagcatgagagc
ccaccccccgcaggctcccctcgctcccccggtggcctgcggccccggggctacacaatc
tccgactcagccccctcgcggcggggcaagagagtggagagggactccttcagaggcaga
gccgctgccgccaacgccgagaaggtgccaggcatcaaccccagcttcgtgttcctgcag
ctctaccactcgcccttctttggagacgagtccaacaagcccattctgctccccaatgag
tcctttgagcggtcagtgcagctgctcgaccagatcccttcctacgacacacacaagatc
gctgttctctatgtgggcgagggccagagcaacagcgagctggcggtcctctccaacgag
cacggctcctacaggtacacggagttcctgacgggcctgggcaagctcatcgagctcaag
gactgccagcccgacaaggtctacctaggcggcctggatgtgggcggcgaggacggccag
ttcacctactgctggcacgatgacatcatgcaagccgtcttccacattgccactctgatg
cccaccaaggacggggaccggcaccgctgtgacaagaagcgtcacctgggcaacgacttt
gtgtccatcgtctacaacgactccggggaagacttcaagttaggcaccatcaagggccag
ttcaactttgtgcacgtgatgatcacgcccctggactacgagtgcaacctggtctccctg
cagtgccgcagagacatggagggcctggtggacaccagtgtggccaagatagtgtctgac
tgcaacctgcccttcgtggcccgccagatggctctgcacgccaacatggcctcccaggtc
caccatagccgctccaaccccaccgatgtctacccctccaagtggatcgcccggcttcgc
catatcaagcgcctgcgccaccggatccgggaggaggcccactgcctgaaccccagcctg
cccctggtgcagacacagccctcggcccccactaagactcaagctgagcccacgcccact
tacgagacgggccagaggaagcgcctcatctcctccgtggacgacttcactgagtttgtc
tga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (9)   
   RefSeq(pep) (9)   
DNA sequence (9)   
   RefSeq(nuc) (9)   
Protein domain (5)   
   Pfam (5)   
All databases (25)   

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