KEGG   Gambusia affinis (western mosquitofish): 122825001
Entry
122825001         CDS       T07758                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4-like isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
gaf  Gambusia affinis (western mosquitofish)
Pathway
gaf00562  Inositol phosphate metabolism
gaf01100  Metabolic pathways
gaf04020  Calcium signaling pathway
gaf04070  Phosphatidylinositol signaling system
gaf04081  Hormone signaling
gaf04082  Neuroactive ligand signaling
gaf04261  Adrenergic signaling in cardiomyocytes
gaf04270  Vascular smooth muscle contraction
gaf04310  Wnt signaling pathway
gaf04371  Apelin signaling pathway
gaf04540  Gap junction
gaf04621  NOD-like receptor signaling pathway
gaf04912  GnRH signaling pathway
gaf04916  Melanogenesis
Module
gaf_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:gaf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    122825001
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    122825001
   04371 Apelin signaling pathway
    122825001
   04020 Calcium signaling pathway
    122825001
   04070 Phosphatidylinositol signaling system
    122825001
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    122825001
   04081 Hormone signaling
    122825001
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    122825001
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    122825001
  09152 Endocrine system
   04912 GnRH signaling pathway
    122825001
   04916 Melanogenesis
    122825001
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    122825001
   04270 Vascular smooth muscle contraction
    122825001
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:gaf04131]
    122825001
Enzymes [BR:gaf01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     122825001
Membrane trafficking [BR:gaf04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    122825001
 Endocytosis
  Macropinocytosis
   Phospholipase C
    122825001
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like PLC-beta_C C2 EF-hand_7 EF-hand_6
Other DBs
NCBI-GeneID: 122825001
NCBI-ProteinID: XP_043961957
Position
LG22:complement(15809320..15870385)
AA seq 1237 aa
MTKSYEFNWQKHLPEFMQEGASFDRFDEDPYLFEPNCQMKVDEYGFFITWKSEGKEGQVL
ECSLINSIRVGAVPKDPKILSSFEAIGKTEADLEGCIICICSGTDLVNLSFMFMVAESPD
TARKWIEGLRSVIHNFKANNVCPMTCLKKHWMRMCFLTNVNGKIPVRGITRTFASGKTEK
GIFQALKDLGLPSGKNDEIEPSDFTFDIFYALTQKICPRTDIEELFKKINGNKTDYLTVD
QLVSFLNENQRDPRLNEILFPFYDPKRATQIIEKYERDEELKKKGRMSSDGFCRYLMSDE
NAPVFLDRLELYQDMDQPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLSGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSDYPVILSFENHCSKLQQYKM
AKYCEELFGDLLLRQPLENYPMDPGHPLPSPNDLKRKILIKNKRLKPEVEQRQLEALKKH
MEAGETNTPAIIMGEENEDDAENGEKESEDKDLNSEAPSILSEVASDKETNNLSQSNLIS
SGKEEKHNNSIKKVPDGEVTEISEATDATDISEASDQDNKKGGDVAEDSEEALIAQYKYE
SATTNIHPYLSAMVNYAQPVKFQGFDVAEERNIHHNMSSFNESVGLGYLKTNAIEFVNYN
KRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTPDLAMQLNQGKFEYNGCCGYLL
KPDFMRRSDRTFDPFSETPVDGVIAATCSVQVFSGQFLSDKKIGTYVEVDMYGLPTDTIR
KEFRTRMVMNNGLNPAYNEEPFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAG
YRHISLRNEGNNPLSLPTVFCQIILKTYVPDGFGAIVDALSDPKKFLTIAEKRADQMKAL
GIDTNDIADVPNGSSKNDKKGKGKGDTGKASVTQQASSDLAQTSNSIQNNTNENKKDTAL
VPNVSIDDLKQMKSYLKLIKKQQKELNSLKKKHSKDQNAMQKAHCTQVDKMVSLHEKEKT
NLEKLLEKAIKKRGENNCQELKKETEDKIQTLTTDHKAKVKDITAQHTKEWSELISSHSS
EEREMKDSHVTQQCEHLKKLLSSVQDQQTLQLKLIHERQSKEMRANQAKMSMENSKAISQ
DKSIKNKAERERRVRELNSSNTKKFLDERKRLAMKHQKEMEQLEKNQREQLDKLEKHNEQ
LLKSHHANKQVQGQGHPADGEVGGGDGPQTCHGGLSD
NT seq 3714 nt   +upstreamnt  +downstreamnt
atgacaaagtcctatgaattcaactggcagaagcacctgcctgagttcatgcaagaaggt
gcctccttcgacaggtttgatgaggacccatacctctttgagcccaactgtcagatgaag
gtggatgaatatggcttctttatcacatggaagagtgagggaaaggaggggcaggttctc
gagtgttctcttatcaacagtatccgtgtcggtgccgtcccaaaggacccaaagatcctg
tcctcattcgaggccataggaaagacagaagccgacctggagggatgcatcatctgcatc
tgcagcggcactgacctggtcaacctgagcttcatgttcatggtggcagagagccccgac
acagccaggaaatggattgagggtttgaggtcggtgatccacaactttaaggccaacaac
gtgtgtccaatgacatgcctcaagaaacattggatgaggatgtgtttcttgaccaatgtc
aacgggaagatccctgttagaggtatcacaagaacctttgcgtcagggaagacagagaaa
gggatctttcaggctctgaaggatctaggtcttcccagtggaaagaatgacgagattgaa
ccctcagacttcacctttgacattttctacgcgctgacacagaagatctgcccccgcaca
gatatagaggagctcttcaagaaaatcaatgggaacaaaacagattatttaactgtagac
cagttagtcagctttctgaatgaaaaccaacgtgacccgaggttaaatgagattctgttt
ccattttacgaccccaaaagagccacgcagatcatcgagaaatatgaaagggacgaagag
ctgaagaaaaaaggccgcatgtcgagtgacgggttctgtcggtacctaatgtcagacgaa
aatgctccagtgttcctggacagactagagctgtaccaagacatggatcagcctttggct
cattattttatcagctcctcccacaacacatacctgacaggaagacagtttggagggaag
tcatcagtggagatgtaccgccaggtcctgctgtctggatgcagatgtgtggagctggac
tgctgggatggcaaaggagaggaccaggaacccatcattactcatggcaaggccatgtgt
acagacatcctgttcaaggatgtgatccaagcaatcaaggagacggcgtttgtcacatct
gattatcctgttattttatcctttgaaaatcattgcagtaaactacagcagtataagatg
gccaagtactgtgaggagctctttggcgacctccttctcaggcagcctctggagaactac
ccaatggatcctgggcatcctttaccttccccaaatgacctgaagagaaaaatcctaata
aagaataagcgattaaaacctgaagtggagcagaggcaacttgaagctttaaagaagcac
atggaggccggtgagaccaacactcctgctatcattatgggagaagagaatgaggacgat
gccgagaacggggaaaaagaatccgaagataaagatttgaattcagaggctcccagcatt
ctgtcagaagtcgccagtgacaaagagacgaacaatctttcccagagtaacctgatcagc
tctggaaaagaggaaaagcacaacaacagcatcaaaaaggtgcctgatggtgaggtcaca
gagatttctgaagcaacagacgccacagatatctctgaggcatctgatcaagacaacaag
aagggcggagacgtggcagaggactctgaggaggctctaatagcgcaatataaatacgag
tcagccaccacaaatatccacccgtatctctcagccatggtcaactatgcacagccggtg
aagttccaggggtttgatgttgcagaagagaggaatatccaccacaacatgtcatccttt
aatgagtcagtgggcctgggctatctgaagaccaacgccatcgagtttgtcaactacaac
aagcgtcagatgagccgtatctaccccaaaggaggcagggtggactccagtaattacatg
cctcagatcttctggaacgcaggctgccagatggtctccctcaacttccagaccccagat
ctggccatgcagctgaaccaaggaaagtttgagtacaacggctgttgtgggtacctgctg
aagccagacttcatgcgtcggtcagacaggacgtttgacccgttctctgagacgccggtg
gatggcgtcattgcagcaacctgcagcgtccaggtgttctcaggacagtttctgtctgac
aaaaaaattggcacgtacgttgaagtcgatatgtacggcttgcctacggatacaatccgg
aaagagttccgcacacgcatggtgatgaacaatggactgaatccagcctacaacgaagag
ccctttgttttcagaaaggtaatcttgccagatctggcggtgctgcgcatcgcagtgtac
gacgacaacaacaagctgattggccaacgcatcctgcctctggacggcctgcaggctggc
taccgtcacatctccctgaggaacgagggcaacaaccctctgtcgttgccgacggtcttc
tgccaaatcatcctcaagacctacgtgcccgacggcttcggagctattgtggatgctcta
tcagacccaaagaagtttttgaccatagcggagaagagagccgaccagatgaaggccctg
gggatcgacacgaacgacatagcagatgttcccaacggaagctcaaagaatgacaagaag
ggaaagggaaaaggagacacagggaaggccagtgtgacacaacaagccagctcagatctg
gcccagacctccaattctatccaaaacaacacaaacgagaacaagaaggatactgcgctt
gtgcctaatgtgagcattgatgacttaaagcaaatgaagagctacctaaagctgattaaa
aagcagcagaaggagctcaactctttaaagaagaaacactcaaaggatcaaaatgcaatg
cagaaagcccattgcactcaggtggacaagatggtgtccctccatgaaaaggaaaagact
aatctggagaaactgctggagaaagccatcaagaaacgaggggagaacaactgccaagag
ctgaagaaggagacagaagataagatccaaactctcaccacagatcataaagcaaaggtg
aaagacatcacagcacaacacactaaggagtggtcggagctcatcagtagtcacagcagc
gaagagcgcgagatgaaggacagtcatgttacccagcagtgtgagcacctcaagaagctc
ctttctagtgtccaggatcagcagaccctgcagctcaaactcattcatgaaaggcaaagc
aaagagatgcgtgccaaccaggccaagatgtccatggaaaacagtaaagcaatcagtcaa
gacaaaagtatcaaaaacaaggcagagcgagagaggagagtgcgggagttaaacagcagc
aacaccaagaagtttttggatgagaggaagaggttggctatgaaacatcagaaggagatg
gagcagctggagaaaaatcagagggagcagttggataaactggagaagcacaacgagcag
cttttgaaatcacaccatgcaaacaaacaggttcaaggccaaggacatccagcagatggt
gaagttggaggaggagatggaccgcagacctgccacggtggtctgagcgactga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (9)   
   Pfam (9)   
All databases (21)   

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