KEGG   Gekko japonicus (Schlegel's Japanese gecko): 107115177
Entry
107115177         CDS       T04299                                 
Symbol
PLCB3
Name
(RefSeq) phospholipase C beta 3
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
gja  Gekko japonicus (Schlegel's Japanese gecko)
Pathway
gja00562  Inositol phosphate metabolism
gja01100  Metabolic pathways
gja04020  Calcium signaling pathway
gja04070  Phosphatidylinositol signaling system
gja04081  Hormone signaling
gja04082  Neuroactive ligand signaling
gja04261  Adrenergic signaling in cardiomyocytes
gja04270  Vascular smooth muscle contraction
gja04310  Wnt signaling pathway
gja04371  Apelin signaling pathway
gja04540  Gap junction
gja04621  NOD-like receptor signaling pathway
gja04912  GnRH signaling pathway
gja04916  Melanogenesis
Module
gja_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:gja00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    107115177 (PLCB3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    107115177 (PLCB3)
   04371 Apelin signaling pathway
    107115177 (PLCB3)
   04020 Calcium signaling pathway
    107115177 (PLCB3)
   04070 Phosphatidylinositol signaling system
    107115177 (PLCB3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    107115177 (PLCB3)
   04081 Hormone signaling
    107115177 (PLCB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    107115177 (PLCB3)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    107115177 (PLCB3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    107115177 (PLCB3)
   04916 Melanogenesis
    107115177 (PLCB3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    107115177 (PLCB3)
   04270 Vascular smooth muscle contraction
    107115177 (PLCB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:gja04131]
    107115177 (PLCB3)
Enzymes [BR:gja01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     107115177 (PLCB3)
Membrane trafficking [BR:gja04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    107115177 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    107115177 (PLCB3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 107115177
NCBI-ProteinID: XP_015272294
UniProt: A0ABM1KF07
Position
Un
AA seq 1206 aa
MAGARPGVHTLQLEPPRVPDTLLKGSKFIKWDEEPTNRALVTLRVDPQGFFLYWTGPSME
VDILDISSIRDTRTGRYAKLPKDPKIREILGFGGSEQHPEDKLVTVVYGPDLVNTSFLNF
MAVVQDDTAKIWTEGLFDLATNILAQNASRNTSLQKAYTRLKLQVNQDGRIPVKNILKMF
SADKKRVETALESCGLNFNRSESIKPDEFTLEIFERFLNKLCLRPDIDKILLEIGAKGKP
YLSLDQLMDFINQKQRDPRLNEVLYPPLTRAQVRQLIDKYEPNQQFQQRDQMSMEGFGRY
LGGEENTIVPPDKLDLSDDMTQPLSSYFINSSHNTYLTAGQLTGNSSVEMYRQVLLSGCR
CIELDCWKGRPQDEEPFITHGFTMTTEIPFKEVIEAIAESAFKTSPFPVILSFENHVDSA
KQQAKMAEYCRNTFGDALLIDPLEKYPLQPGVALPSPQELMGRILVKNKKRRPHSKISEG
SVRKRVLEQTPSSYSDTSSVAEPGSPPLGSPLAEQQEPLSPIMTNGEEKSSERIPKLVEP
RKSIDREAESEEEEEQQELKKPTTDEGTASSEAIATEEMSTLVNYIEPVKFKSFEVASKR
NKSYEMSSFVETRGLEQLTNSPMEFVEYNKKQLSRIYPKGTRVDSSNYMPQVFWNAGCQL
VALNFQSLDLPMQLNLGIFEYNRRSGYLLKPEFMRRQDKPFDPFTEDIVDGIVANTVKVK
IISGQFLSDKRVGIYVEVDMFGLPVDTKRKFRTRTSQGNSFNPVWDEEPFVFHKVVLPTL
ASLRIAVFEEGGKFVGHRILPVSAIRSGYHYICLRSESNQLLCLPALLVYTEAYDYIPDD
HQNYAEALINPIKHVSLMDQRAKQLAALIGESEECTEKPRESLGRSRSDASSSPPEEACK
PPRALLSPTRSPSVVPSQVQRDDLIASVLAEVSPQSVEELRQHKAFVKLLKKQYRELKEL
RRKHMKKICSLNKKQNAQLSQVERSRQRSREGSPRGSLSSMEATRQGQGQEVTRRMLELQ
EWQMQGLLQLREAQHQLERDCKREHLHQAQQRLREIARDCQAAQLKKLKEMGEKEKKELQ
KILDRKRHNSITEAKSREKSKKDVELTEINRRHITESVNSIRRLEEAQKRRQEKLLAGHQ
GILQLIEEEEPRLAAQLEDECELESVSLPQEISRYLQEELDGGISNGHPPGSNACPSPAE
EELTVL
NT seq 3621 nt   +upstreamnt  +downstreamnt
atggccggggcgcgcccgggggtccacacgctccagctggagcccccgcgtgtcccggac
accctgctcaagggcagcaagttcatcaagtgggacgaggaaccaaccaatcgggctctt
gtgaccctgcgggtggacccacaagggtttttcctctactggactggccccagcatggaa
gttgacattctggacatcagctctatccgggacactcggaccgggcgatacgccaaactc
cccaaggacccgaagatccgagagatacttggctttgggggctcggagcaacaccctgag
gataagttggtgacggttgtgtatggccctgacctggtcaacaccagcttcctcaacttc
atggcggttgtccaggatgacacggctaagatatggacggagggactgttcgatctggcc
accaacatcttagctcagaacgcttcccggaacacctctttgcagaaagcttatacccgg
cttaaactccaagtcaatcaggatgggaggattcctgttaagaacattctcaaaatgttc
tccgccgacaagaagcgggtcgagacagccttggagtcctgcggccttaattttaacagg
agcgagtccatcaaacctgacgagttcaccctggagatcttcgaacgcttcctgaacaag
ctttgccttcgcccagacatagacaaaatcttgctggagattggagccaagggaaagcct
tacctgagtttggaccagctgatggacttcattaaccagaagcagcgggacccccgtctc
aacgaggttctgtaccccccactgactcgggcccaggtgcggcagctaattgacaagtac
gagcccaatcagcagttccagcaacgtgaccagatgtcgatggaagggtttggtcgttac
ctggggggagaggagaacaccattgtgcctcctgacaagctggatttaagtgacgacatg
acccagcctctaagcagctacttcattaattcctcacataatacctacctcacagctggg
cagctgacaggcaattcctcggtagagatgtatcgccaggtgctgctgagcggctgccgt
tgcatcgagcttgactgttggaagggacgcccccaagacgaggagcccttcatcacacac
ggattcactatgacaacagagatacccttcaaggaagtcatagaggccattgctgaaagt
gccttcaagacgtcgccttttcctgtcatcctttcgtttgagaatcacgtggactcggca
aagcagcaggcaaagatggcggagtattgccgaaacacctttggggatgctctgctcatt
gatcccttggaaaaatatccgttacagcccggtgtagccttgccaagtccccaggagttg
atgggccggatcttggtgaagaacaagaagcgtcgcccacacagcaagatctccgagggc
agcgtgcggaagcgggtgctggaacagacacccagctcctacagtgatacctcaagcgtg
gctgagccagggtctcccccactgggttctcctctggcagaacagcaagaacccctttcg
ccaattatgaccaacggcgaggagaaatcatctgagcgaatacctaagctggttgaaccc
cgcaagtctatcgatcgtgaagctgagagtgaagaagaggaggagcagcaagaactgaag
aagcccacaacagatgagggcactgccagtagcgaggccatcgccacagaggagatgtcc
acgttggtgaactacatcgaacccgtcaagttcaaatcctttgaggtggccagcaaacgc
aacaaatcctacgagatgtcttcgtttgtggagaccagaggcctggagcagctaaccaac
agccccatggagtttgttgaatacaacaagaagcaactcagccggatataccctaaaggg
acccgggtggattcttccaactacatgcctcaggtcttctggaatgccggctgccaattg
gtggcgctcaacttccagtctcttgacttgccaatgcagctgaatctgggcatcttcgaa
tacaaccgccgaagcgggtacttgctgaagccagagttcatgcggcgccaggacaagccc
tttgaccccttcaccgaagacattgtcgatggcatcgtagccaacaccgtcaaagtgaag
ataatctcagggcaattcttgtctgacaagcgagtggggatctatgtcgaagtggacatg
tttgggctgccggtggacaccaagcgcaaattccgcacgcggacgtcgcaggggaattcc
ttcaacccagtgtgggatgaagagccttttgttttccacaaggtggtgcttcctacactg
gcctccctccgcatagccgtctttgaagaagggggcaagtttgtggggcacaggatactg
ccagtctctgccatccgctcaggatatcactacatttgcctgcgcagtgaaagcaatcag
ctgctgtgtctcccggccttgctggtctatacggaggcctacgactatattccagatgat
caccaaaattatgcggaggccctgattaaccccatcaagcacgtcagcttaatggaccag
cgggcgaagcagctggcagccctgataggggagagcgaggagtgcacagagaagccacgg
gagtccctgggaaggagccgctccgatgcaagctcctccccccctgaagaagcgtgcaag
cccccacgagctttactgtcccccacccggagccccagtgtggtccccagccaagtgcag
agggacgatctgatcgccagcgtcctggcagaggtctccccacagtctgtggaagagctg
aggcagcacaaagctttcgtgaaactgctgaagaagcagtaccgggagctgaaggagctg
cggcggaagcacatgaagaagatctgcagcctgaacaagaagcagaacgcacagctgtcc
caggtggaaaggagccggcagcgtagccgggaagggtccccccgtggctccctgagctcc
atggaggccacacggcagggccaggggcaggaagtgacccgccggatgctggagctgcag
gagtggcagatgcaggggctgctccagctgcgggaggcccagcaccagctggagagggac
tgcaagcgagaacatctgcaccaggcccagcagcgcctgagggaaattgcccgtgactgt
caagctgcccagctgaagaaactgaaggagatgggtgagaaagagaagaaagagcttcag
aaaatcctggaccgaaaacggcacaacagcatcacagaggccaaatcccgtgagaagagt
aaaaaagatgttgagctgacggagataaacaggagacacatcactgagtcagtgaactcc
attcgcaggctcgaggaagcccagaagcggcgacaggagaagctgctggcgggccaccag
gggatcctgcagctcatcgaggaagaagagccgcggttggcagcccaactagaagacgag
tgtgaactggaaagcgtctccctcccccaagagatcagccgctacctgcaggaagagctg
gacggcggcatcagcaacggacacccgcccggatctaacgcttgcccaagccctgccgaa
gaagagctgacggtgctgtga

  All links  
Gene (27)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (37)   

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