KEGG   Geotrypetes seraphini (Gaboon caecilian): 117364320
Entry
117364320         CDS       T09159                                 
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
gsh  Geotrypetes seraphini (Gaboon caecilian)
Pathway
gsh00562  Inositol phosphate metabolism
gsh01100  Metabolic pathways
gsh04020  Calcium signaling pathway
gsh04070  Phosphatidylinositol signaling system
gsh04081  Hormone signaling
gsh04082  Neuroactive ligand signaling
gsh04261  Adrenergic signaling in cardiomyocytes
gsh04270  Vascular smooth muscle contraction
gsh04310  Wnt signaling pathway
gsh04371  Apelin signaling pathway
gsh04540  Gap junction
gsh04621  NOD-like receptor signaling pathway
gsh04912  GnRH signaling pathway
gsh04916  Melanogenesis
Module
gsh_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:gsh00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    117364320 (PLCB2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    117364320 (PLCB2)
   04371 Apelin signaling pathway
    117364320 (PLCB2)
   04020 Calcium signaling pathway
    117364320 (PLCB2)
   04070 Phosphatidylinositol signaling system
    117364320 (PLCB2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    117364320 (PLCB2)
   04081 Hormone signaling
    117364320 (PLCB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    117364320 (PLCB2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    117364320 (PLCB2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    117364320 (PLCB2)
   04916 Melanogenesis
    117364320 (PLCB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    117364320 (PLCB2)
   04270 Vascular smooth muscle contraction
    117364320 (PLCB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:gsh04131]
    117364320 (PLCB2)
Enzymes [BR:gsh01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     117364320 (PLCB2)
Membrane trafficking [BR:gsh04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    117364320 (PLCB2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    117364320 (PLCB2)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 117364320
NCBI-ProteinID: XP_033809301
UniProt: A0A6P8RXA8
Position
7:122514843..122680842
AA seq 1215 aa
MSNLTQVLAPPQVKEYLCKGERFIKWDDETTIASPVILRVDPKGYYLYWTFQSKEMEFLD
LTSIRDTRFGKFAKIPKSQKLRDVFNLDFPENNFLAKTLTIVSGSDMVDLTFHNFVSYKE
NVGKDWAADVLTIVRNPLVANASRYSFLEKILVKLKLQLNAEAKIPVRNIFQLFPADRKR
VESALSACHLPKGKNDAINPEDFPESVYRTFLMQLCPRPEIDEIFTSYHSKAKPYMTKDH
LTKFINKKQRDSRLSDVLFPPAKTDQVQGLIEKYEPSVINIQRGQLSPEGMVWFLCGAEN
SITSLEKLIVNQDMTQPLSHYFINSSHNTYLTAGQFSGVSSPEMYRQTLLAGCRCVELDC
WKGKPPEEEPIITHGFTMTTEILFKDVIEAIAESAFKTSSYPVILSFENHVDSPKQQAKM
AEYCRTIFGDMLLTEPLEKYPLKPGFPLPSPQDLLGKILIKNKKNLCSQDSEKKSRSSET
ESVEQTSMPNIDNADMSSGDVPEEELENEEDIESLNEEAMKKMQSDEGTAGLEVTAYEEM
SSLVNYIQPIKFDSFDISAQRNRSYVISSFVETKAYELLTKFPVQFVEYNKRQMSRIYPK
GTRMDSSNYMPHMFWNAGCQMVALNFQTMDLPMQLNMSLFEFNGRSGYLIKHEFMRQVDK
QFDPFTVDRIDVVVANTLSITILSGQFLSERSIKTYVEVELFGLPGDPKRKYKTKVTSSP
NSINPVWKEDAFVFEKILMPELASLRVAVLEEGGKFIGHRIIPVNAVQSGFHHICLHSES
NMPLTMPSLFVYVEVKDYVPDTWADLTSALSNPIKFFNARDKKFVKDKDSASVTEKQQVS
NINGMLKPSKVLHISTSNGPAGTTPSVAQNVSKEATEPQTANLEELQKQKGYVKLQRKQE
KELKEIERKSGKRKEELLQRYAMLFTELRSQGGRKRSITWKNQKKKRSLTEDGSVWGDAA
EILEIADPRILELKQKLEVDLRQLEEELYEGIQKKKEQHSAEQIGKLMELAQEKQTSELK
SLKESAESDSKQMKKKLEVKRQERIETMTKANTDKATQERLKREINHSHIQEVVHVLQLM
SIKSGNQQKILEKKQLACLEKIKEKGTQSQQQVQTEHQEKTKALAMEIRDTVQSCMKIWF
PLELQGPKEDTLNSVNPGEEQSQKDSADSEIPHNVQEEDEEELPPGETSSKTPLQESEEG
VNERVQILSTTANLP
NT seq 3648 nt   +upstreamnt  +downstreamnt
atgtcaaatctcacccaggtcctggcgcccccgcaggtgaaggaatacctctgcaagggg
gagcgcttcatcaagtgggacgatgaaaccaccattgcttctcctgtaattctgcgagtg
gatcccaaaggttattatttatactggacttttcagagcaaggaaatggagtttttggac
ttaaccagcattcgggacactagatttggaaaatttgctaaaatccccaagagtcagaaa
cttcgagatgtatttaacttggactttcctgaaaacaacttcctggcaaaaaccttgacc
attgtgtcaggctctgacatggtggacctcacctttcacaactttgtctcctacaaagag
aatgttggcaaggattgggcagcagatgttctgactattgtcagaaacccactcgtggcc
aacgcttcccggtactccttcctggagaaaatattagtgaaattaaagctacagctcaat
gcagaggcaaagattcctgttcgcaacatttttcagttgtttccagcagacaggaaaagg
gtagaaagtgcattgagtgcctgtcacctccccaagggcaagaatgatgctatcaatcca
gaagattttccagagtctgtttatagaacattcctcatgcaactgtgtccacgaccagag
attgatgagatatttacttcttatcactcaaaagcaaagccctatatgacgaaagatcac
ttaacaaagtttataaataagaagcaacgagattcccgcctcagtgatgtcctgttccca
cctgcaaaaactgatcaggttcaaggcctgatagaaaaatacgaaccaagtgtgattaac
atccagagaggtcagctgtctccagaagggatggtctggttcctgtgcggagcagagaac
agtatcacatcactggagaaattaatagtgaaccaggacatgacacagcctctctcacat
tacttcatcaactcttcacacaacacctacctcacagctggccagttttctggagtctca
tcccctgaaatgtatcgtcagaccctactggccggctgccgctgtgtagagctagactgc
tggaagggaaagcccccggaggaggagcccattataactcatggctttaccatgacaact
gagatcttattcaaggacgtgattgaggcgatcgcagaaagtgcttttaaaacctcctct
taccctgtcatcctttcctttgagaatcatgttgattctcccaagcagcaagccaaaatg
gcagagtactgcagaacaatctttggagacatgttgctgacggaacctctagaaaaatat
cctctcaaaccagggtttcccctgcccagtccccaggatctgctgggaaaaattttgatt
aagaacaagaagaacctgtgcagtcaggactccgaaaagaagagccggagcagtgaaacc
gagtcagtggagcagactagcatgccaaacattgacaatgcagatatgtcgtcaggtgac
gtgcctgaggaagagctggagaatgaagaagacatagaaagcctcaatgaagaagctatg
aaaaagatgcagtcagacgagggaacagctggcttggaagtcacagcctatgaagaaatg
tccagtcttgtcaactacatccagcccatcaaatttgattcatttgacatctcagcacag
aggaaccggagttatgtcatttcctcctttgtggagaccaaagcctatgaactgctgacg
aagttcccagtgcagtttgttgaatataacaagcgacaaatgagtaggatttatcccaaa
ggcaccaggatggactcttcaaactacatgcctcatatgttctggaatgctggctgtcag
atggtggcattgaattttcagaccatggacttacctatgcaactgaatatgtctctcttt
gagttcaatggtcgcagtggttatcttatcaaacatgagttcatgcgccaggtagacaaa
cagtttgacccattcacagtggaccgcatcgatgtagttgtggcaaacaccctctctata
acgatcctttctggacagttcctttcggagcgtagcataaagacttatgtagaagtggaa
ctgtttggacttccaggagacccgaaacgtaaatataagactaaagtaacatcatctcct
aactctatcaacccagtatggaaggaagatgcctttgtttttgaaaagattttaatgcca
gagttggcatctctcagagtggcagtgcttgaggaaggagggaagttcattggccaccgc
ataatacctgtgaatgctgtgcaatcaggattccaccacatttgccttcacagcgagagt
aacatgcctctcaccatgccttctctatttgtttatgtggaggtgaaagattatgttcct
gatacatgggcagatcttaccagtgctctgtccaaccctatcaagttcttcaacgcccgt
gataagaagttcgttaaggacaaggatagtgcttcagtcacagagaaacaacaggtctct
aacattaatggaatgctgaagcccagcaaggttctgcacatctccacttccaatggacct
gcaggaactacaccctccgtggcacaaaatgtcagcaaagaagctacagagcctcagacc
gccaacctggaggagctacagaaacaaaaagggtatgtcaagttgcagaggaagcaggaa
aaggagctgaaggagatagagcggaagagcggcaagcgcaaagaggagcttctgcagaga
tacgccatgctcttcactgagcttcgcagccagggaggcaggaagagaagcattacctgg
aaaaatcagaagaagaaaaggagtttaacagaagatggtagtgtatggggagatgcagca
gagatactggagatcgctgatccccggatcctggagctaaagcagaaactggaggttgat
ctgcgacagctggaggaagagctgtatgaaggaattcagaaaaaaaaagagcaacattct
gcagagcaaatcggcaaactgatggagctggcacaagagaagcagacgagtgagctgaaa
agcctgaaggaatcagcagagagtgacagtaaacagatgaaaaagaagctggaggttaag
aggcaagagcgaatagaaactatgaccaaagctaatacagacaaggcaactcaagagagg
ttaaagagagaaattaatcattcacatatccaggaagtggtacacgttctccaactgatg
agcataaaatctggcaaccagcaaaagatcttggagaaaaagcagctagcttgcctggag
aagataaaagaaaaaggaactcagtcacaacagcaggtacagacggaacatcaggagaag
acaaaagcccttgccatggaaattcgggacacagtacagagctgtatgaagatctggttt
ccacttgagttacagggtccaaaggaagacacactaaattcagttaacccaggggaggaa
cagtcccagaaagactctgccgactctgaaatcccccacaatgttcaggaagaagatgag
gaagaacttccacctggagagaccagctccaaaacgcctctacaggaatcagaagaggga
gtgaatgaacgtgtacagatcttgtctacaaccgctaatctcccctaa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (14)   

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