KEGG   Hyperoodon ampullatus (northern bottlenose whale): 307058811
Entry
307058811         CDS       T11951                                 
Symbol
MAPK13
Name
(RefSeq) mitogen-activated protein kinase 13
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
hamp  Hyperoodon ampullatus (northern bottlenose whale)
Pathway
hamp01522  Endocrine resistance
hamp04010  MAPK signaling pathway
hamp04015  Rap1 signaling pathway
hamp04068  FoxO signaling pathway
hamp04071  Sphingolipid signaling pathway
hamp04114  Oocyte meiosis
hamp04148  Efferocytosis
hamp04218  Cellular senescence
hamp04261  Adrenergic signaling in cardiomyocytes
hamp04370  VEGF signaling pathway
hamp04380  Osteoclast differentiation
hamp04517  IgSF CAM signaling
hamp04519  Cadherin signaling
hamp04550  Signaling pathways regulating pluripotency of stem cells
hamp04611  Platelet activation
hamp04613  Neutrophil extracellular trap formation
hamp04620  Toll-like receptor signaling pathway
hamp04621  NOD-like receptor signaling pathway
hamp04622  RIG-I-like receptor signaling pathway
hamp04625  C-type lectin receptor signaling pathway
hamp04657  IL-17 signaling pathway
hamp04658  Th1 and Th2 cell differentiation
hamp04659  Th17 cell differentiation
hamp04660  T cell receptor signaling pathway
hamp04664  Fc epsilon RI signaling pathway
hamp04668  TNF signaling pathway
hamp04670  Leukocyte transendothelial migration
hamp04714  Thermogenesis
hamp04722  Neurotrophin signaling pathway
hamp04723  Retrograde endocannabinoid signaling
hamp04728  Dopaminergic synapse
hamp04750  Inflammatory mediator regulation of TRP channels
hamp04912  GnRH signaling pathway
hamp04914  Progesterone-mediated oocyte maturation
hamp04917  Prolactin signaling pathway
hamp04926  Relaxin signaling pathway
hamp04932  Non-alcoholic fatty liver disease
hamp04933  AGE-RAGE signaling pathway in diabetic complications
hamp04935  Growth hormone synthesis, secretion and action
hamp04936  Alcoholic liver disease
hamp05014  Amyotrophic lateral sclerosis
hamp05020  Prion disease
hamp05022  Pathways of neurodegeneration - multiple diseases
hamp05132  Salmonella infection
hamp05133  Pertussis
hamp05135  Yersinia infection
hamp05140  Leishmaniasis
hamp05142  Chagas disease
hamp05145  Toxoplasmosis
hamp05152  Tuberculosis
hamp05161  Hepatitis B
hamp05163  Human cytomegalovirus infection
hamp05167  Kaposi sarcoma-associated herpesvirus infection
hamp05169  Epstein-Barr virus infection
hamp05170  Human immunodeficiency virus 1 infection
hamp05171  Coronavirus disease
hamp05205  Proteoglycans in cancer
hamp05208  Chemical carcinogenesis - reactive oxygen species
hamp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hamp05415  Diabetic cardiomyopathy
hamp05417  Lipid and atherosclerosis
hamp05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hamp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    307058811 (MAPK13)
   04015 Rap1 signaling pathway
    307058811 (MAPK13)
   04370 VEGF signaling pathway
    307058811 (MAPK13)
   04668 TNF signaling pathway
    307058811 (MAPK13)
   04068 FoxO signaling pathway
    307058811 (MAPK13)
   04071 Sphingolipid signaling pathway
    307058811 (MAPK13)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    307058811 (MAPK13)
   04519 Cadherin signaling
    307058811 (MAPK13)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    307058811 (MAPK13)
  09143 Cell growth and death
   04114 Oocyte meiosis
    307058811 (MAPK13)
   04218 Cellular senescence
    307058811 (MAPK13)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    307058811 (MAPK13)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    307058811 (MAPK13)
   04613 Neutrophil extracellular trap formation
    307058811 (MAPK13)
   04620 Toll-like receptor signaling pathway
    307058811 (MAPK13)
   04621 NOD-like receptor signaling pathway
    307058811 (MAPK13)
   04622 RIG-I-like receptor signaling pathway
    307058811 (MAPK13)
   04625 C-type lectin receptor signaling pathway
    307058811 (MAPK13)
   04660 T cell receptor signaling pathway
    307058811 (MAPK13)
   04658 Th1 and Th2 cell differentiation
    307058811 (MAPK13)
   04659 Th17 cell differentiation
    307058811 (MAPK13)
   04657 IL-17 signaling pathway
    307058811 (MAPK13)
   04664 Fc epsilon RI signaling pathway
    307058811 (MAPK13)
   04670 Leukocyte transendothelial migration
    307058811 (MAPK13)
  09152 Endocrine system
   04912 GnRH signaling pathway
    307058811 (MAPK13)
   04914 Progesterone-mediated oocyte maturation
    307058811 (MAPK13)
   04917 Prolactin signaling pathway
    307058811 (MAPK13)
   04926 Relaxin signaling pathway
    307058811 (MAPK13)
   04935 Growth hormone synthesis, secretion and action
    307058811 (MAPK13)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    307058811 (MAPK13)
  09156 Nervous system
   04728 Dopaminergic synapse
    307058811 (MAPK13)
   04723 Retrograde endocannabinoid signaling
    307058811 (MAPK13)
   04722 Neurotrophin signaling pathway
    307058811 (MAPK13)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    307058811 (MAPK13)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    307058811 (MAPK13)
  09159 Environmental adaptation
   04714 Thermogenesis
    307058811 (MAPK13)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    307058811 (MAPK13)
   05208 Chemical carcinogenesis - reactive oxygen species
    307058811 (MAPK13)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    307058811 (MAPK13)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    307058811 (MAPK13)
   05161 Hepatitis B
    307058811 (MAPK13)
   05171 Coronavirus disease
    307058811 (MAPK13)
   05163 Human cytomegalovirus infection
    307058811 (MAPK13)
   05167 Kaposi sarcoma-associated herpesvirus infection
    307058811 (MAPK13)
   05169 Epstein-Barr virus infection
    307058811 (MAPK13)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    307058811 (MAPK13)
   05135 Yersinia infection
    307058811 (MAPK13)
   05133 Pertussis
    307058811 (MAPK13)
   05152 Tuberculosis
    307058811 (MAPK13)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    307058811 (MAPK13)
   05140 Leishmaniasis
    307058811 (MAPK13)
   05142 Chagas disease
    307058811 (MAPK13)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    307058811 (MAPK13)
   05020 Prion disease
    307058811 (MAPK13)
   05022 Pathways of neurodegeneration - multiple diseases
    307058811 (MAPK13)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    307058811 (MAPK13)
   05418 Fluid shear stress and atherosclerosis
    307058811 (MAPK13)
   05415 Diabetic cardiomyopathy
    307058811 (MAPK13)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    307058811 (MAPK13)
   04932 Non-alcoholic fatty liver disease
    307058811 (MAPK13)
   04933 AGE-RAGE signaling pathway in diabetic complications
    307058811 (MAPK13)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    307058811 (MAPK13)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hamp01001]
    307058811 (MAPK13)
Enzymes [BR:hamp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     307058811 (MAPK13)
Protein kinases [BR:hamp01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   307058811 (MAPK13)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kinase-like
Other DBs
NCBI-GeneID: 307058811
NCBI-ProteinID: XP_079568622
Position
10:<68109332..68119411
AA seq 366 aa
MNLTWKKGFYKQDVNKTAWELPKTYVSLMHVGSGAYGAVCSAIDKQSGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMQHENVIGLLDAFTSASSLRNFHDFYLVMPFMQTDLQKIMGM
EFGEDKIQYLVYQMLKGLKYIHSAGVIHRDLKPGNLAVNEDCELKILDFGLARHADAEMT
GYVVTRWYRAPEVILSWMRYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPDAEFVQKLNDKAAKSYIQSLPQNPKKDFSLLFPRASPQAADLLEKMLELDVHKRLTAS
QALTHPFFESCRDPEEETEAQQPFDDFLEQEELTVDEWKHHIYKEIVNFSPIARKDSRRR
SGMKLQ
NT seq 1101 nt   +upstreamnt  +downstreamnt
atgaacctcacctggaaaaagggcttctacaagcaggacgtcaacaagaccgcctgggag
ctgcccaagacctacgtgtccctgatgcacgtaggcagcggggcctacggcgccgtgtgc
tcagccatcgacaagcagtcaggggagaaggtggccatcaagaaactgagccggcccttc
cagtctgagatctttgccaagcgggcctatcgcgagctgctgctgctgaagcacatgcag
catgagaacgtcatcggactcctggatgccttcacctcagcctcttccctgcgcaacttt
catgatttctacctggtgatgcccttcatgcagacggacctgcagaagatcatgggaatg
gagttcggtgaggacaagatccagtacctggtgtatcagatgctcaaaggtcttaagtac
atccactcagctggggtcatccacagggacctgaaaccaggcaaccttgctgtgaatgag
gattgtgagctgaagattttggattttgggttggcacggcatgcagatgcagagatgact
ggctatgtggtgacccgctggtaccgggcccctgaggtgatcctcagctggatgcgctac
aaccagactgtggacatctggtctgtgggctgtatcatggcagagatgctgacagggaaa
actctgttcaaggggaaagattacctggaccagctgacgcagatcctgaaagtgacgggg
gtgccggacgctgagtttgtgcagaagttgaatgacaaagcggccaaatcctacatccag
tccctgccacaaaaccccaagaaggatttctctctgctcttcccgcgtgccagcccccag
gctgcagacctgctggagaagatgctggagctggacgtacacaagcgcctgactgcctct
caggccctcacccaccccttctttgaatcctgccgggaccctgaggaggaaacagaggcc
cagcagccatttgatgatttcttagaacaggaggagctcacagtggatgaatggaagcat
cacatttacaaggagattgtgaacttcagccccatcgcccggaaggactctcggcgccgg
agtggcatgaagctgcagtga

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