KEGG   Hyperoodon ampullatus (northern bottlenose whale): 307060759
Entry
307060759         CDS       T11951                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor 1
  KO
K05459  insulin-like growth factor 1
Organism
hamp  Hyperoodon ampullatus (northern bottlenose whale)
Pathway
hamp01521  EGFR tyrosine kinase inhibitor resistance
hamp01522  Endocrine resistance
hamp04010  MAPK signaling pathway
hamp04014  Ras signaling pathway
hamp04015  Rap1 signaling pathway
hamp04066  HIF-1 signaling pathway
hamp04068  FoxO signaling pathway
hamp04081  Hormone signaling
hamp04114  Oocyte meiosis
hamp04115  p53 signaling pathway
hamp04150  mTOR signaling pathway
hamp04151  PI3K-Akt signaling pathway
hamp04152  AMPK signaling pathway
hamp04211  Longevity regulating pathway
hamp04213  Longevity regulating pathway - multiple species
hamp04510  Focal adhesion
hamp04518  Integrin signaling
hamp04550  Signaling pathways regulating pluripotency of stem cells
hamp04730  Long-term depression
hamp04750  Inflammatory mediator regulation of TRP channels
hamp04913  Ovarian steroidogenesis
hamp04914  Progesterone-mediated oocyte maturation
hamp04935  Growth hormone synthesis, secretion and action
hamp04960  Aldosterone-regulated sodium reabsorption
hamp05200  Pathways in cancer
hamp05202  Transcriptional misregulation in cancer
hamp05205  Proteoglycans in cancer
hamp05214  Glioma
hamp05215  Prostate cancer
hamp05218  Melanoma
hamp05224  Breast cancer
hamp05410  Hypertrophic cardiomyopathy
hamp05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:hamp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    307060759 (IGF1)
   04014 Ras signaling pathway
    307060759 (IGF1)
   04015 Rap1 signaling pathway
    307060759 (IGF1)
   04066 HIF-1 signaling pathway
    307060759 (IGF1)
   04068 FoxO signaling pathway
    307060759 (IGF1)
   04151 PI3K-Akt signaling pathway
    307060759 (IGF1)
   04152 AMPK signaling pathway
    307060759 (IGF1)
   04150 mTOR signaling pathway
    307060759 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    307060759 (IGF1)
   04518 Integrin signaling
    307060759 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    307060759 (IGF1)
   04115 p53 signaling pathway
    307060759 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    307060759 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    307060759 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    307060759 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    307060759 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    307060759 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    307060759 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    307060759 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    307060759 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    307060759 (IGF1)
   04213 Longevity regulating pathway - multiple species
    307060759 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    307060759 (IGF1)
   05202 Transcriptional misregulation in cancer
    307060759 (IGF1)
   05205 Proteoglycans in cancer
    307060759 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    307060759 (IGF1)
   05218 Melanoma
    307060759 (IGF1)
   05215 Prostate cancer
    307060759 (IGF1)
   05224 Breast cancer
    307060759 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    307060759 (IGF1)
   05414 Dilated cardiomyopathy
    307060759 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    307060759 (IGF1)
   01522 Endocrine resistance
    307060759 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hamp04052]
    307060759 (IGF1)
Cytokines and neuropeptides [BR:hamp04052]
 Cytokines
  Growth factors (RTK binding)
   307060759 (IGF1)
SSDB
Motif
Pfam: Insulin DUF2865
Other DBs
NCBI-GeneID: 307060759
NCBI-ProteinID: XP_079571599
Position
11:<26520298..26576333
AA seq 207 aa
MGKISSLPTQLFKCCFCDFLKVKMHITSSSHLFYLALFLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKAQKYQPPSTNKKTKSQRRRKGGPKKHPGGEQKEGTEASQKQMKGKKKEQ
RRETGARNEQGQKGKRRRAGLRQRQGG
NT seq 624 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtaaagatgcacatcacgtcctcctcgcatctcttctacttggccctgttcttgctc
accttcaccagctctgccacggctggacccgagaccctctgtggggctgagttggtggac
gcccttcagttcgtgtgcggagacaggggcttttatttcaacaagcccacggggtatggc
tcgagcagtcggagggcgcctcagacaggaatcgtggatgaatgctgcttccggagctgt
gatctgaggaggctggagatgtactgcgcgcctctcaagcctgccaagtcagcccgctct
gtacgtgcccagcgccacaccgacatgcccaaggctcagaagtatcagcccccatccacc
aacaagaaaacgaagtctcagaggagaaggaaaggtgggccaaagaaacatccaggaggg
gaacagaaggaggggacggaagcaagtcagaagcagatgaaaggcaagaagaaagagcag
aggagggagactggagctagaaatgaacaaggccagaaaggaaaacggaggagagcagga
ctaagacagaggcaaggaggatga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (6)   

Download RDF
DBGET integrated database retrieval system