KEGG   Heterocephalus glaber (naked mole-rat): 101707684
Entry
101707684         CDS       T02812                                 
Symbol
Igf1
Name
(RefSeq) insulin like growth factor 1
  KO
K05459  insulin-like growth factor 1
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl01521  EGFR tyrosine kinase inhibitor resistance
hgl01522  Endocrine resistance
hgl04010  MAPK signaling pathway
hgl04014  Ras signaling pathway
hgl04015  Rap1 signaling pathway
hgl04066  HIF-1 signaling pathway
hgl04068  FoxO signaling pathway
hgl04081  Hormone signaling
hgl04114  Oocyte meiosis
hgl04115  p53 signaling pathway
hgl04150  mTOR signaling pathway
hgl04151  PI3K-Akt signaling pathway
hgl04152  AMPK signaling pathway
hgl04211  Longevity regulating pathway
hgl04213  Longevity regulating pathway - multiple species
hgl04510  Focal adhesion
hgl04518  Integrin signaling
hgl04550  Signaling pathways regulating pluripotency of stem cells
hgl04730  Long-term depression
hgl04750  Inflammatory mediator regulation of TRP channels
hgl04913  Ovarian steroidogenesis
hgl04914  Progesterone-mediated oocyte maturation
hgl04935  Growth hormone synthesis, secretion and action
hgl04960  Aldosterone-regulated sodium reabsorption
hgl05200  Pathways in cancer
hgl05202  Transcriptional misregulation in cancer
hgl05205  Proteoglycans in cancer
hgl05214  Glioma
hgl05215  Prostate cancer
hgl05218  Melanoma
hgl05224  Breast cancer
hgl05410  Hypertrophic cardiomyopathy
hgl05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101707684 (Igf1)
   04014 Ras signaling pathway
    101707684 (Igf1)
   04015 Rap1 signaling pathway
    101707684 (Igf1)
   04066 HIF-1 signaling pathway
    101707684 (Igf1)
   04068 FoxO signaling pathway
    101707684 (Igf1)
   04151 PI3K-Akt signaling pathway
    101707684 (Igf1)
   04152 AMPK signaling pathway
    101707684 (Igf1)
   04150 mTOR signaling pathway
    101707684 (Igf1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    101707684 (Igf1)
   04518 Integrin signaling
    101707684 (Igf1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    101707684 (Igf1)
   04115 p53 signaling pathway
    101707684 (Igf1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101707684 (Igf1)
   04550 Signaling pathways regulating pluripotency of stem cells
    101707684 (Igf1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    101707684 (Igf1)
   04914 Progesterone-mediated oocyte maturation
    101707684 (Igf1)
   04935 Growth hormone synthesis, secretion and action
    101707684 (Igf1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    101707684 (Igf1)
  09156 Nervous system
   04730 Long-term depression
    101707684 (Igf1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101707684 (Igf1)
  09149 Aging
   04211 Longevity regulating pathway
    101707684 (Igf1)
   04213 Longevity regulating pathway - multiple species
    101707684 (Igf1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101707684 (Igf1)
   05202 Transcriptional misregulation in cancer
    101707684 (Igf1)
   05205 Proteoglycans in cancer
    101707684 (Igf1)
  09162 Cancer: specific types
   05214 Glioma
    101707684 (Igf1)
   05218 Melanoma
    101707684 (Igf1)
   05215 Prostate cancer
    101707684 (Igf1)
   05224 Breast cancer
    101707684 (Igf1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    101707684 (Igf1)
   05414 Dilated cardiomyopathy
    101707684 (Igf1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101707684 (Igf1)
   01522 Endocrine resistance
    101707684 (Igf1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hgl04052]
    101707684 (Igf1)
Cytokines and neuropeptides [BR:hgl04052]
 Cytokines
  Growth factors (RTK binding)
   101707684 (Igf1)
SSDB
Motif
Pfam: Insulin Fijivirus_P9-2
Other DBs
NCBI-GeneID: 101707684
NCBI-ProteinID: XP_004844899
UniProt: A0A0N8EUV1
Position
Un
AA seq 153 aa
MGKISSLPTQLFKCCFCDFLKVRMRSVSFSHLFYLALCLLAFTGSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPPKSARS
VRAQRHTDLPKTPKEVHLKNASRGSAGNRNYRM
NT seq 462 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaactcaattatttaagtgctgcttttgtgatttcttg
aaggtcaggatgcgctccgtgtccttttcgcacctcttctacctggccctctgcttgctc
gccttcaccggctcggccacagcggggccggagactctctgcggggcggagctggtcgac
gcgcttcagttcgtgtgtggagacaggggcttttacttcaacaagcccacggggtacggc
tccagcagtcggcgggcgccccagaccggcatcgtggacgagtgctgcttccggagctgc
gacctgcggcggctggagatgtactgcgccccgctcaagccccccaagtcagcccgctcc
gtgcgcgcccagcgccacaccgacctgcccaagacccccaaggaagtacatttgaagaat
gcgagtagggggagtgcaggaaacaggaactacaggatgtag

  All links  
Gene (9)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (6)   
   RefSeq(nuc) (2)   
   GenBank (2)   
   EMBL (2)   
Protein domain (2)   
   Pfam (2)   
All databases (20)   

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