KEGG   Homo sapiens (human): 120356740
Entry
120356740         CDS       T01001                                 
Symbol
TOMT, COMT2
Name
(RefSeq) transmembrane O-methyltransferase
  KO
K00545  catechol O-methyltransferase [EC:2.1.1.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00140  Steroid hormone biosynthesis
hsa00350  Tyrosine metabolism
hsa01100  Metabolic pathways
hsa04728  Dopaminergic synapse
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    120356740 (TOMT)
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    120356740 (TOMT)
 09150 Organismal Systems
  09156 Nervous system
   04728 Dopaminergic synapse
    120356740 (TOMT)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    120356740 (TOMT)
   04147 Exosome [BR:hsa04147]
    120356740 (TOMT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.6  catechol O-methyltransferase
     120356740 (TOMT)
Cilium and associated proteins [BR:hsa03037]
 Other cilia and associated proteins
  Stereociliary proteins
   120356740 (TOMT)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   120356740 (TOMT)
SSDB
Motif
Pfam: Methyltransf_3 Methyltransf_24 PCMT GCD14
Other DBs
NCBI-GeneID: 120356740
NCBI-ProteinID: NP_001380429
HGNC: 55527
Ensembl: ENSP00000494667.1
UniProt: A0A2R8Y5M8
Position
11:72105924..72109596
AA seq 258 aa
MSPAIALAFLPLVVTLLVRYRHYFRLLVRTVLLRSLRDCLSGLRIEERAFSYVLTHALPG
DPGHILTTLDHWSSRCEYLSHMGPVKGQILMRLVEEKAPACVLELGTYCGYSTLLIARAL
PPGGRLLTVERDPRTAAVAEKLIRLAGFDEHMVELIVGSSEDVIPCLRTQYQLSRADLVL
LAHRPRCYLRDLQLLEAHALLPAGATVLADHVLFPGAPRFLQYAKSCGRYRCRLHHTGLP
DFPAIKDGIAQLTYAGPG
NT seq 777 nt   +upstreamnt  +downstreamnt
atgtcccctgccattgcattggccttcctgccactggtggtaacattgctggtgcggtac
cggcactacttccgattgctggtgcgcacggtcttgctgcgaagcctccgagactgcctg
tcagggctgcggatcgaggagcgggccttcagctacgtgctcacccatgccctgcccggt
gaccctggtcacatcctcaccaccctggaccactggagcagccgctgcgagtacttgagc
cacatggggcctgtcaaaggtcagatcctgatgcggctggtggaggagaaggcccctgct
tgtgtgctggaattgggaacctactgtggatactctaccctgcttattgcccgagccctg
ccccctgggggtcgccttcttactgtggagcgggacccacgcacggcagcagtggctgaa
aaactcatccgcctggccggctttgatgagcacatggtggagctcatcgtgggcagctca
gaggacgtgatcccgtgcctacgcacccagtatcagctgagtcgggcagacctggtgctc
ctggcacaccggccacgatgttacctgagggacctgcagctgctggaggcccatgcccta
ctgccagcaggtgccaccgtgctggctgaccatgtgctcttccctggtgcaccccgcttc
ttgcagtatgctaagagctgtggccgctaccgctgccgcctccaccacactggccttcca
gacttccctgccatcaaggatggaatagctcagctcacctatgctggaccaggctga

  All links  
Gene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (11)   

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