KEGG   Homo sapiens (human): 22798
Entry
22798             CDS       T01001                                 
Symbol
LAMB4
Name
(RefSeq) laminin subunit beta-4 isoform 1 precursor
  KO
K06245  laminin, beta 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04518  Integrin signaling
hsa05145  Toxoplasmosis
hsa05146  Amoebiasis
hsa05165  Human papillomavirus infection
hsa05200  Pathways in cancer
hsa05222  Small cell lung cancer
Network
nt06548  Integrin signaling
  Element
N01987  Integrin alpha1beta1 signaling
N01988  Integrin alpha2beta1 signaling
N01990  Integrin alpha3beta1 signaling
N01991  Integrin alpha6beta1 signaling
N01992  Integrin alpha6beta4 signaling
N01997  Integrin alpha7beta1 signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    22798 (LAMB4)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    22798 (LAMB4)
   04518 Integrin signaling
    22798 (LAMB4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    22798 (LAMB4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    22798 (LAMB4)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    22798 (LAMB4)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    22798 (LAMB4)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    22798 (LAMB4)
   05145 Toxoplasmosis
    22798 (LAMB4)
SSDB
Motif
Pfam: EGF_laminin Laminin_N EGF_LMN_ATRN LAMININ_IV_B LAMB4 LAMB1
Other DBs
NCBI-GeneID: 22798
NCBI-ProteinID: NP_001304975
OMIM: 616380
HGNC: 6491
UniProt: A4D0S4 B4DTV7 B7ZMJ6
Position
7:complement(108011662..108130361)
AA seq 1761 aa
MQFQLTLFLHLGWLSYSKAQDDCNRGACHPTTGDLLVGRNTQLMASSTCGLSRAQKYCIL
SYLEGEQKCFICDSRFPYDPYDQPNSHTIENVIVSFEPDREKKWWQSENGLDHVSIRLDL
EALFRFSHLILTFKTFRPAAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGD
IVCDSKYSDIEPSTGGEVVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDAL
LGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHN
TDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCE
DCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVA
GQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSY
VTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPA
PGYFFAPLNFYLYEAEEATTLQGLAPLGSETFGQSPAVHVVLGEPVPGNPVTWTGPGFAR
VLPGAGLRFAVNNIPFPVDFTIAIHYETQSAADWTVQIVVNPPGGSEHCIPKTLQSKPQS
FALPAATRIMLLPTPICLEPDVQYSIDVYFSQPLQGESHAHSHVLVDSLGLIPQINSLEN
FCSKQDLDEYQLHNCVEIASAMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSS
CSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHG
EVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYG
NPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNP
RISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCR
RCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSC
DCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPIC
DPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLA
ANMEDKRETLPVCEADFKDLRGNVSEIERILKHPVFPSGKFLKVKDYHDSVRRQIMQLNE
QLKAVYEFQDLKDTIERAKNEADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSS
AEKKINETSSTINTSANTRNDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPG
NVPCVPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLK
NQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIE
KVANGVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAE
KAANILLNLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELEL
AKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVELKKQYAILQRKT
STTGLTKETLGKVKQLKDAAEKLAGDTEAKIRRITDLERKIQDLNLSRQAKADQLRILED
QVVAIKNEIVEQEKKYARCYS
NT seq 5286 nt   +upstreamnt  +downstreamnt
atgcaatttcaactgaccctttttttgcaccttgggtggctcagttactcaaaagctcaa
gatgactgcaacaggggtgcctgtcatcccaccactggtgatctcctggtgggcaggaac
acgcagcttatggcttcttctacctgtgggctgagcagagcccagaaatactgcatcctc
agttacctggagggggaacaaaaatgcttcatctgtgactctagatttccatatgatccg
tatgaccaacccaacagccacaccattgagaatgtcattgtaagttttgaaccagacaga
gaaaagaaatggtggcaatctgaaaatggtcttgatcatgtcagcatcagactggactta
gaggcattatttcggttcagccaccttatcctgacctttaagacttttcggcctgctgca
atgttagttgaacgttccacagactatggacacaactggaaagtgttcaaatattttgca
aaagactgtgccacttcctttcctaacatcacatctggccaggcccagggagtgggagac
attgtttgtgactccaaatactcggatattgaaccctcaacaggtggagaggttgtttta
aaagttttggatcccagttttgaaattgaaaacccttatagcccctacatccaagacctt
gtgacattgacaaacctgaggataaactttaccaagctccacacccttggggatgctttg
cttggaaggaggcaaaatgattcccttgataaatactactatgctctgtacgagatgatt
gttcggggaagctgcttttgcaatggccatgctagcgaatgtcgccctatgcagaagatg
cggggagatgttttcagccctcctggaatggttcacggtcagtgtgtgtgtcagcacaat
acagatggtccgaactgtgagagatgcaaggacttcttccaggatgctccttggaggcca
gctgcagacctccaggacaacgcttgcagatcgtgcagctgtaatagccactccagccgc
tgtcactttgacatgactacgtacctggcaagcggtggcctcagcgggggcgtgtgtgaa
gactgccagcacaacactgaggggcagcactgcgaccgctgcagacccctcttctacagg
gacccgctcaagaccatctcagatccctacgcgtgcattccttgtgaatgtgaccccgat
gggaccatatctggtggcatttgtgtgagccactctgatcctgccttagggtctgtggcc
ggccagtgcctttgtaaagagaacgtggaaggagccaaatgcgaccagtgcaaacccaac
cactacggactaagcgccaccgaccccctgggctgccagccctgcgactgtaaccccctt
gggagtctgccattcttgacctgtgatgtggatacaggccaatgcttgtgcctgtcatat
gtcaccggagcacactgcgaagaatgcactgttggatactggggcctgggaaatcatctc
catgggtgttctccctgtgactgtgatattggaggtgcttattctaacgtgtgctcaccc
aagaatgggcagtgtgaatgccgcccacatgtcactggccgtagctgctctgaaccagcc
cctggctacttctttgctcctttgaatttctatctctacgaggcagaggaagccacaaca
ctccaaggactggcgcctttgggctcggagacgtttggccagagtcctgctgttcacgtt
gttttaggagagccagttcctgggaaccctgttacatggactggacctggatttgccagg
gttctccctggggctggcttgagatttgctgtcaacaacattccctttcctgtggacttc
accattgccattcactatgaaacccagtctgcagctgactggactgtccagattgtggtg
aacccccctggagggagtgagcactgcatacccaagactctacagtcaaagcctcagtct
tttgccttaccagcggctacgagaatcatgctgcttcccacacccatctgtttagaacca
gatgtacaatattccatagatgtctatttttctcagcctttgcaaggagagtcccacgct
cattcacatgtcctggtggactctcttggccttattccccaaatcaattcattggagaat
ttctgcagcaagcaggacttagatgagtatcagcttcacaactgtgttgaaattgcctca
gcaatgggacctcaagtgctcccgggtgcctgtgaaaggctgatcatcagcatgtctgcc
aagctgcatgatggggctgtggcctgcaagtgtcacccccagggctcagtcggatccagc
tgcagccgacttggaggccagtgccagtgtaaacctcttgtggtcgggcgctgctgtgac
aggtgctcaactggaagctatgatttggggcatcacggctgtcacccatgtcactgccat
cctcaaggatcaaaggacactgtatgtgaccaagtaacaggacagtgcccctgccatgga
gaggtgtctggccgccgctgtgatcgctgcctggcaggctactttggatttcccagctgc
cacccttgcccttgtaataggtttgctgaactttgtgatcctgagacagggtcatgcttc
aattgtggaggctttacaactggcagaaactgtgaaaggtgtattgatggttactatgga
aatccttcttcaggacagccctgtcgtccttgcctgtgtccagatgatccctcaagcaat
cagtattttgcccattcctgttatcagaatctgtggagctcagatgtaatctgcaattgt
cttcaaggttatacgggtactcagtgtggagaatgctctactggtttctatggaaatcca
agaatttcaggagcaccttgccaaccatgtgcctgcaacaacaacatagatgtaaccgat
ccagagtcctgcagccgggtaacaggggagtgccttcgatgtttgcacaacactcagggc
gcaaactgccagctctgcaaaccaggtcactatggatcagccctcaatcagacctgcaga
agatgctcctgccatgcttccggcgtgagtcccatggagtgtccccctggtgggggagct
tgcctctgtgaccctgtcactggtgcatgtccttgtctgccgaatgtcacaggcctggcc
tgtgaccgttgtgctgatggatactggaatctggtccctggcagaggatgtcagtcatgt
gactgtgaccctaggacctctcaaagtagccactgtgaccagcttacaggccagtgtccg
tgtaaattaggttacggcgggaaacgttgcagtgagtgccaggaaaattattatggtgat
ccacctgggcgatgcattccatgtgattgtaacagggcaggtacccagaagcccatctgt
gatccagacacaggcatgtgccgctgccgggagggtgtcagcggccagagatgtgatcgc
tgtgcccggggacacagccaggaattccctacttgtcttcaatgtcacttgtgctttgat
cagtgggaccacaccatttcttccctctccaaagcggtgcaagggttaatgagactggct
gctaacatggaagataaaagagagaccctgcctgtctgtgaggcagacttcaaagacctc
agagggaacgtgtctgaaatagaaaggattttgaaacatcctgttttcccatctgggaaa
ttcttaaaagtcaaggattatcatgactctgttagaagacaaatcatgcagctaaatgaa
caactgaaagcagtgtatgaatttcaagatctgaaagatacaatagaaagagcaaagaat
gaagcagacctcttacttgaagaccttcaggaagaaattgatttgcaatccagtgtcctt
aatgcaagcattgcggactcctcagaaaacatcaagaaatattatcacatatcatcatct
gctgaaaagaaaattaatgaaactagttccaccattaatacctctgcaaatacaaggaat
gacttacttaccatcttagatacactaacctcaaaaggaaacttgtcattggaaagatta
aagcagattaagataccagatatccaaatattgaatgaaaaggtgtgcggagatccagga
aatgtgccatgtgtgcccttgccctgtggcggtgctctctgcacgggccggaaggggcac
aggaagtgtaggggtcccggctgtcacggctccctgaccctctcaacgaatgccctccaa
aaagcccaggaagcaaaatccattattcgtaatttggacaaacaggttcgtgggttgaaa
aatcagatcgaaagtataagtgaacaggcagaagtctccaaaaacaatgccttacagctg
agggaaaaactgggaaatataagaaaccaaagtgactctgaagaagaaaacatcaatctt
ttcatcaaaaaagtgaaaaactttttgttagaggaaaacgtgcctccagaagacatcgag
aaggttgcgaatggtgtgcttgacattcacctaccaattccatcccaaaatctaaccgat
gaacttgtcaaaatacagaaacatatgcaactctgtgaggattacaggacagatgaaaac
aggttaaatgaagaagcagatggagcccaaaagcttttggtgaaggccaaagcagctgag
aaagcagcaaatattctattaaatcttgacaaaacattgaaccagttacaacaagctcaa
atcactcaaggacgggcaaactctaccattacacagctgactgccaatataacaaaaata
aaaaagaatgtgctgcaggctgaaaatcaaaccagggaaatgaagagtgagctggagtta
gcaaagcagcgatcagggctggaggatggactttccctgctgcagaccaagttgcaaagg
catcaagaccacgctgtcaatgcgaaagttcaggctgaatctgcccaacaccaggctggg
agtcttgagaaggaatttgttgagctgaaaaaacaatatgctattctccaacgtaagaca
agcactacaggactaacaaaggagacattaggaaaagttaaacagctaaaagatgcggca
gaaaaattggctggagatacagaggccaagataagaagaataacagatttagaaaggaaa
atccaagatttgaatctaagtagacaagcaaaagctgatcaactgagaatattggaagat
caagttgttgccattaaaaatgaaattgttgaacaagaaaaaaaatatgctaggtgctat
agctag

  All links  
Disease (1)   
   OMIM (1)   
Gene (86)   
   RefGene (81)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (20)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (16)   
DNA sequence (40)   
   RefSeq(nuc) (20)   
   GenBank (10)   
   EMBL (10)   
Protein domain (6)   
   Pfam (6)   
All databases (153)   

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