KEGG   Homo sapiens (human): 22974
Entry
22974             CDS       T01001                                 
Symbol
TPX2, C20orf1, C20orf2, DIL-2, DIL2, FLS353, GD:C20orf1, HCA519, HCTP4, REPP86, p100
Name
(RefSeq) targeting protein for Xklp2
  KO
K16812  targeting protein for Xklp2
Organism
hsa  Homo sapiens (human)
Network
nt06515  Regulation of kinetochore-microtubule interactions
  Element
N01544  Microtubule nucleation
N01549  Branching microtubule nucleation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    22974 (TPX2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Spindle formation proteins
    22974 (TPX2)
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     22974 (TPX2)
SSDB
Motif
Pfam: TPX2_importin Aurora-A_bind TPX2
Other DBs
NCBI-GeneID: 22974
NCBI-ProteinID: NP_036244
OMIM: 605917
HGNC: 1249
Ensembl: ENSP00000300403.6
UniProt: Q9ULW0 Q643R0
Structure
Position
20:31739290..31801800
AA seq 747 aa
MSQVKSSYSYDAPSDFINFSSLDDEGDTQNIDSWFEEKANLENKLLGKNGTGGLFQGKTP
LRKANLQQAIVTPLKPVDNTYYKEAEKENLVEQSIPSNACSSLEVEAAISRKTPAQPQRR
SLRLSAQKDLEQKEKHHVKMKAKRCATPVIIDEILPSKKMKVSNNKKKPEEEGSAHQDTA
EKNASSPEKAKGRHTVPCMPPAKQKFLKSTEEQELEKSMKMQQEVVEMRKKNEEFKKLAL
AGIGQPVKKSVSQVTKSVDFHFRTDERIKQHPKNQEEYKEVNFTSELRKHPSSPARVTKG
CTIVKPFNLSQGKKRTFDETVSTYVPLAQQVEDFHKRTPNRYHLRSKKDDINLLPSKSSV
TKICRDPQTPVLQTKHRARAVTCKSTAELEAEELEKLQQYKFKARELDPRILEGGPILPK
KPPVKPPTEPIGFDLEIEKRIQERESKKKTEDEHFEFHSRPCPTKILEDVVGVPEKKVLP
ITVPKSPAFALKNRIRMPTKEDEEEDEPVVIKAQPVPHYGVPFKPQIPEARTVEICPFSF
DSRDKERQLQKEKKIKELQKGEVPKFKALPLPHFDTINLPEKKVKNVTQIEPFCLETDRR
GALKAQTWKHQLEEELRQQKEAACFKARPNTVISQEPFVPKKEKKSVAEGLSGSLVQEPF
QLATEKRAKERQELEKRMAEVEAQKAQQLEEARLQEEEQKKEELARLRRELVHKANPIRK
YQGLEIKSSDQPLTVPVSPKFSTRFHC
NT seq 2244 nt   +upstreamnt  +downstreamnt
atgtcacaagttaaaagctcttattcctatgatgccccctcggatttcatcaatttttca
tccttggatgatgaaggagatactcaaaacatagattcatggtttgaggagaaggccaat
ttggagaataagttactggggaagaatggaactggagggctttttcagggcaaaactcct
ttgagaaaggctaatcttcagcaagctattgtcacacctttgaaaccagttgacaacact
tactacaaagaggcagaaaaagaaaatcttgtggaacaatccattccgtcaaatgcttgt
tcttccctggaagttgaggcagccatatcaagaaaaactccagcccagcctcagagaaga
tctcttaggctttctgctcagaaggatttggaacagaaagaaaagcatcatgtaaaaatg
aaagccaagagatgtgccactcctgtaatcatcgatgaaattctaccctctaagaaaatg
aaagtttctaacaacaaaaagaagccagaggaagaaggcagtgctcatcaagatactgct
gaaaagaatgcatcttccccagagaaagccaagggtagacatactgtgccttgtatgcca
cctgcaaagcagaagtttctaaaaagtactgaggagcaagagctggagaagagtatgaaa
atgcagcaagaggtggtggagatgcggaaaaagaatgaagaattcaagaaacttgctctg
gctggaatagggcaacctgtgaagaaatcagtgagccaggtcaccaaatcagttgacttc
cacttccgcacagatgagcgaatcaaacaacatcctaagaaccaggaggaatataaggaa
gtgaactttacatctgaactacgaaagcatccttcatctcctgcccgagtgactaaggga
tgtaccattgttaagcctttcaacctgtcccaaggaaagaaaagaacatttgatgaaaca
gtttctacatatgtgccccttgcacagcaagttgaagacttccataaacgaacccctaac
agatatcatttgaggagcaagaaggatgatattaacctgttaccctccaaatcttctgtg
accaagatttgcagagacccacagactcctgtactgcaaaccaaacaccgtgcacgggct
gtgacctgcaaaagtacagcagagctggaggctgaggagctcgagaaattgcaacaatac
aaattcaaagcacgtgaacttgatcccagaatacttgaaggtgggcccatcttgcccaag
aaaccacctgtgaaaccacccaccgagcctattggctttgatttggaaattgagaaaaga
atccaggagcgagaatcaaagaagaaaacagaggatgaacactttgaatttcattccaga
ccttgccctactaagattttggaagatgttgtgggtgttcctgaaaagaaggtacttcca
atcaccgtccccaagtcaccagcctttgcattgaagaacagaattcgaatgcccaccaaa
gaagatgaggaagaggacgaaccggtagtgataaaagctcaacctgtgccacattatggg
gtgccttttaagccccaaatcccagaggcaagaactgtggaaatatgccctttctcgttt
gattctcgagacaaagaacgtcagttacagaaggagaagaaaataaaagaactgcagaaa
ggggaggtgcccaagttcaaggcacttcccttgcctcattttgacaccattaacctgcca
gagaagaaggtaaagaatgtgacccagattgaacctttctgcttggagactgacagaaga
ggtgctctgaaggcacagacttggaagcaccagctggaagaagaactgagacagcagaaa
gaagcagcttgtttcaaggctcgtccaaacaccgtcatctctcaggagccctttgttccc
aagaaagagaagaaatcagttgctgagggcctttctggttctctagttcaggaacctttt
cagctggctactgagaagagagccaaagagcggcaggagctggagaagagaatggctgag
gtagaagcccagaaagcccagcagttggaggaggccagactacaggaggaagagcagaaa
aaagaggagctggccaggctacggagagaactggtgcataaggcaaatccaatacgcaag
taccagggtctggagataaagtcaagtgaccagcctctgactgtgcctgtatctcccaaa
ttctccactcgattccactgctaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (25)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (11)   
   OC (1)   
Protein sequence (14)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (45)   
   RefSeq(nuc) (11)   
   GenBank (17)   
   EMBL (17)   
3D Structure (13)   
   PDB (13)   
Protein domain (3)   
   Pfam (3)   
All databases (101)   

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