KEGG   Homo sapiens (human): 23439
Entry
23439             CDS       T01001                                 
Symbol
ATP1B4
Name
(RefSeq) ATPase Na+/K+ transporting family member beta 4
  KO
K01540  sodium/potassium-transporting ATPase subunit beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04260  Cardiac muscle contraction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04911  Insulin secretion
hsa04918  Thyroid hormone synthesis
hsa04919  Thyroid hormone signaling pathway
hsa04925  Aldosterone synthesis and secretion
hsa04960  Aldosterone-regulated sodium reabsorption
hsa04961  Endocrine and other factor-regulated calcium reabsorption
hsa04964  Proximal tubule bicarbonate reclamation
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion
hsa04973  Carbohydrate digestion and absorption
hsa04974  Protein digestion and absorption
hsa04976  Bile secretion
hsa04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    23439 (ATP1B4)
   04022 cGMP-PKG signaling pathway
    23439 (ATP1B4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    23439 (ATP1B4)
   04918 Thyroid hormone synthesis
    23439 (ATP1B4)
   04919 Thyroid hormone signaling pathway
    23439 (ATP1B4)
   04925 Aldosterone synthesis and secretion
    23439 (ATP1B4)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    23439 (ATP1B4)
   04261 Adrenergic signaling in cardiomyocytes
    23439 (ATP1B4)
  09154 Digestive system
   04970 Salivary secretion
    23439 (ATP1B4)
   04971 Gastric acid secretion
    23439 (ATP1B4)
   04972 Pancreatic secretion
    23439 (ATP1B4)
   04976 Bile secretion
    23439 (ATP1B4)
   04973 Carbohydrate digestion and absorption
    23439 (ATP1B4)
   04974 Protein digestion and absorption
    23439 (ATP1B4)
   04978 Mineral absorption
    23439 (ATP1B4)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    23439 (ATP1B4)
   04961 Endocrine and other factor-regulated calcium reabsorption
    23439 (ATP1B4)
   04964 Proximal tubule bicarbonate reclamation
    23439 (ATP1B4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    23439 (ATP1B4)
CD molecules [BR:hsa04090]
 Proteins
  23439 (ATP1B4)
SSDB
Motif
Pfam: Na_K-ATPase Gcd10p
Other DBs
NCBI-GeneID: 23439
NCBI-ProteinID: NP_001135919
OMIM: 301073
HGNC: 808
Ensembl: ENSG00000101892
Pharos: Q9UN42(Tdark)
UniProt: Q9UN42
Position
X:120362089..120383237
AA seq 357 aa
MRRQLRSRRAPSFPYSYRYRLDDPDEANQNYLADEEEEAEEEARVTVVPKSEEEEEEEEK
EEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTGQSWSLILLIYFFFY
ASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPFAHSLNFNFNVSEPDTWQHYVI
SLNGFLQGYNDSLQEEMNVDCPPGQYFIQDGNEDEDKKACQFKRSFLKNCSGLEDPTFGY
STGQPCILLKMNRIVGFRPELGDPVKVSCKVQRGDENDIRSISYYPESASFDLRYYPYYG
KLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGVINDVINDRFVGRVIFTLNIET
NT seq 1074 nt   +upstreamnt  +downstreamnt
atgagaaggcaactccggtccagaagggctccatcctttccttacagttatcgctacaga
ctcgatgatccggatgaagcgaaccagaactacttagcagatgaagaggaggaagcagaa
gaagaggctcgggtgacggtggtgcccaaatcggaggaggaggaagaagaggaggagaaa
gaagaggaggaagaggaggaaaaggaggaggaagagggtcaaggtcagccaacaggcaat
gcctggtggcagaaattgcagatcatgagtgaatacctgtgggatccagagagaaggatg
tttctggcccgaacaggtcagagttggagcctgatcttactcatttacttcttcttctat
gcctccttggctgctgtgatcaccctctgcatgtacacactatttctgaccatcagtccc
tatataccaaccttcacggagcgggtaaagcctcctggagttatgatcagacccttcgcc
catagccttaacttcaacttcaacgtttctgaacccgacacttggcagcattatgtgatt
agcctaaatggctttctccagggttataatgacagtcttcaagaggaaatgaatgtagat
tgtcccccggggcagtacttcatccaagatggcaatgaggatgaggacaagaaggcctgc
caatttaagcgctccttcctaaagaactgctctggtctggaggacccaacttttggatac
tctactggacagccctgcatccttctaaagatgaaccggattgtaggctttcgtcctgag
cttggagatcctgtgaaggtttcctgcaaagttcagagaggtgatgaaaatgacatccga
tccatcagttactacccagagtcggcttcttttgacctccgctactacccttactacggc
aaactgactcacgttaactacacatcccccttggtggcaatgcactttacagacgtggtg
aagaaccaagcagtgcctgtgcagtgccaactgaagggcaaaggcgtcataaatgatgtc
atcaatgatcgttttgtgggcagggtaatctttaccctgaacatagaaacttaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (18)   
   KEGG PATHWAY (18)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (22)   
   RefSeq(nuc) (4)   
   GenBank (9)   
   EMBL (9)   
Protein domain (2)   
   Pfam (2)   
All databases (64)   

Download RDF
KEGG   Homo sapiens (human): 476
Entry
476               CDS       T01001                                 
Symbol
ATP1A1, CMT2DD, HOMGSMR2
Name
(RefSeq) ATPase Na+/K+ transporting subunit alpha 1
  KO
K01539  sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04260  Cardiac muscle contraction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04911  Insulin secretion
hsa04918  Thyroid hormone synthesis
hsa04919  Thyroid hormone signaling pathway
hsa04925  Aldosterone synthesis and secretion
hsa04960  Aldosterone-regulated sodium reabsorption
hsa04961  Endocrine and other factor-regulated calcium reabsorption
hsa04964  Proximal tubule bicarbonate reclamation
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion
hsa04973  Carbohydrate digestion and absorption
hsa04974  Protein digestion and absorption
hsa04976  Bile secretion
hsa04978  Mineral absorption
Network
nt06316  Angiotensin-aldosterone signaling
  Element
N00304  Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway
Disease
H00264  Charcot-Marie-Tooth disease
H01210  Hypomagnesemia
H01603  Primary aldosteronism
Drug target
Acetyldigitoxin: D06881
Acetyldigoxin: D07555
Bepridil (DG00333): D00631<JP> D07520
Bretylium tosilate: D00645
Deslanoside: D01240<JP>
Digitoxin: D00297
Digoxin: D00298<JP/US>
G-strophanthin: D00112
Gitoformate: D07147
Lanatoside C: D01972
Metildigoxin (DG00191): D02587<JP> D09847
Proscillaridin: D01379
beta-Acetyldigoxin: D07556
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    476 (ATP1A1)
   04022 cGMP-PKG signaling pathway
    476 (ATP1A1)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    476 (ATP1A1)
   04918 Thyroid hormone synthesis
    476 (ATP1A1)
   04919 Thyroid hormone signaling pathway
    476 (ATP1A1)
   04925 Aldosterone synthesis and secretion
    476 (ATP1A1)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    476 (ATP1A1)
   04261 Adrenergic signaling in cardiomyocytes
    476 (ATP1A1)
  09154 Digestive system
   04970 Salivary secretion
    476 (ATP1A1)
   04971 Gastric acid secretion
    476 (ATP1A1)
   04972 Pancreatic secretion
    476 (ATP1A1)
   04976 Bile secretion
    476 (ATP1A1)
   04973 Carbohydrate digestion and absorption
    476 (ATP1A1)
   04974 Protein digestion and absorption
    476 (ATP1A1)
   04978 Mineral absorption
    476 (ATP1A1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    476 (ATP1A1)
   04961 Endocrine and other factor-regulated calcium reabsorption
    476 (ATP1A1)
   04964 Proximal tubule bicarbonate reclamation
    476 (ATP1A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    476 (ATP1A1)
Enzymes [BR:hsa01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.13  Na+/K+-exchanging ATPase
     476 (ATP1A1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   476 (ATP1A1)
  Exosomal proteins of other body fluids (saliva and urine)
   476 (ATP1A1)
  Exosomal proteins of colorectal cancer cells
   476 (ATP1A1)
  Exosomal proteins of bladder cancer cells
   476 (ATP1A1)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Hydrolase Cation_ATPase_N Hydrolase_3
Other DBs
NCBI-GeneID: 476
NCBI-ProteinID: NP_000692
OMIM: 182310
HGNC: 799
Ensembl: ENSG00000163399
Pharos: P05023(Tclin)
UniProt: P05023
Structure
Position
1:116373244..116404774
AA seq 1023 aa
MGKGVGRDKYEPAAVSEQGDKKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLS
RGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAA
TEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSI
NAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETR
NIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAV
FLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKN
LEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLA
LSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEI
PFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQN
AYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVP
DAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDA
KACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVN
DSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTL
TSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPK
TDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVED
SYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFE
ETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKE
TYY
NT seq 3072 nt   +upstreamnt  +downstreamnt
atggggaagggggttggacgtgataagtatgagcctgcagctgtttcagaacaaggtgat
aaaaagggcaaaaagggcaaaaaagacagggacatggatgaactgaagaaagaagtttct
atggatgatcataaacttagccttgatgaacttcatcgtaaatatggaacagacttgagc
cggggattaacatctgctcgtgcagctgagatcctggcgcgagatggtcccaacgccctc
actccccctcccactactcctgaatggatcaagttttgtcggcagctctttggggggttc
tcaatgttactgtggattggagcgattctttgtttcttggcttatagcatccaagctgct
acagaagaggaacctcaaaacgataatctgtacctgggtgtggtgctatcagccgttgta
atcataactggttgcttctcctactatcaagaagctaaaagttcaaagatcatggaatcc
ttcaaaaacatggtccctcagcaagcccttgtgattcgaaatggtgagaaaatgagcata
aatgcggaggaagttgtggttggggatctggtggaagtaaaaggaggagaccgaattcct
gctgacctcagaatcatatctgcaaatggctgcaaggtggataactcctcgctcactggt
gaatcagaaccccagactaggtctccagatttcacaaatgaaaaccccctggagacgagg
aacattgccttcttttcaaccaattgtgttgaaggcaccgcacgtggtattgttgtctac
actggggatcgcactgtgatgggaagaattgccacacttgcttctgggctggaaggaggc
cagacccccattgctgcagaaattgaacattttatccacatcatcacgggtgtggctgtg
ttcctgggtgtgtctttcttcatcctttctctcatccttgagtacacctggcttgaggct
gtcatcttcctcatcggtatcatcgtagccaatgtgccggaaggtttgctggccactgtc
acggtctgtctgacacttactgccaaacgcatggcaaggaaaaactgcttagtgaagaac
ttagaagctgtggagaccttggggtccacgtccaccatctgctctgataaaactggaact
ctgactcagaaccggatgacagtggcccacatgtggtttgacaatcaaatccatgaagct
gatacgacagagaatcagagtggtgtctcttttgacaagacttcagctacctggcttgct
ctgtccagaattgcaggtctttgtaacagggcagtgtttcaggctaaccaggaaaaccta
cctattcttaagcgggcagttgcaggagatgcctctgagtcagcactcttaaagtgcata
gagctgtgctgtggttccgtgaaggagatgagagaaagatacgccaaaatcgtcgagata
cccttcaactccaccaacaagtaccagttgtctattcataagaaccccaacacatcggag
ccccaacacctgttggtgatgaagggcgccccagaaaggatcctagaccgttgcagctct
atcctcctccacggcaaggagcagcccctggatgaggagctgaaagacgcctttcagaac
gcctatttggagctggggggcctcggagaacgagtcctaggtttctgccacctctttctg
ccagatgaacagtttcctgaagggttccagtttgacactgacgatgtgaatttccctatc
gataatctgtgctttgttgggctcatctccatgattgaccctccacgggcggccgttcct
gatgccgtgggcaaatgtcgaagtgctggaattaaggtcatcatggtcacaggagaccat
ccaatcacagctaaagctattgccaaaggtgtgggcatcatctcagaaggcaatgagacc
gtggaagacattgctgcccgcctcaacatcccagtcagccaggtgaaccccagggatgcc
aaggcctgcgtagtacacggcagtgatctaaaggacatgacctccgagcagctggatgac
attttgaagtaccacactgagatagtgtttgccaggacctcccctcagcagaagctcatc
attgtggaaggctgccaaagacagggtgctatcgtggctgtgactggtgacggtgtgaat
gactctccagctttgaagaaagcagacattggggttgctatggggattgctggctcagat
gtgtccaagcaagctgctgacatgattcttctggatgacaactttgcctcaattgtgact
ggagtagaggaaggtcgtctgatctttgataacttgaagaaatccattgcttatacctta
accagtaacattcccgagatcaccccgttcctgatatttattattgcaaacattccacta
ccactggggactgtcaccatcctctgcattgacttgggcactgacatggttcctgccatc
tccctggcttatgagcaggctgagagtgacatcatgaagagacagcccagaaatcccaaa
acagacaaacttgtgaatgagcggctgatcagcatggcctatgggcagattggaatgatc
caggccctgggaggcttctttacttactttgtgattctggctgagaacggcttcctccca
attcacctgttgggcctccgagtggactgggatgaccgctggatcaacgatgtggaagac
agctacgggcagcagtggacctatgagcagaggaaaatcgtggagttcacctgccacaca
gccttcttcgtcagtatcgtggtggtgcagtgggccgacttggtcatctgtaagaccagg
aggaattcggtcttccagcaggggatgaagaacaagatcttgatatttggcctctttgaa
gagacagccctggctgctttcctttcctactgccctggaatgggtgttgctcttaggatg
tatcccctcaaacctacctggtggttctgtgccttcccctactctcttctcatcttcgta
tatgacgaagtcagaaaactcatcatcaggcgacgccctggcggctgggtggagaaggaa
acctactattag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (18)   
   KEGG PATHWAY (18)   
Network (1)   
   KEGG NETWORK (1)   
Disease (6)   
   KEGG DISEASE (3)   
   OMIM (3)   
Drug (15)   
   KEGG DRUG (15)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (37)   
   KEGG ORTHOLOGY (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
   PHAROS (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (38)   
   RefSeq(nuc) (4)   
   GenBank (17)   
   EMBL (17)   
3D Structure (3)   
   PDB (3)   
Protein domain (6)   
   Pfam (6)   
All databases (134)   

Download RDF
KEGG   Homo sapiens (human): 477
Entry
477               CDS       T01001                                 
Symbol
ATP1A2, DEE98, FARIMPD, FHM2, MHP2
Name
(RefSeq) ATPase Na+/K+ transporting subunit alpha 2
  KO
K01539  sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04260  Cardiac muscle contraction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04911  Insulin secretion
hsa04918  Thyroid hormone synthesis
hsa04919  Thyroid hormone signaling pathway
hsa04925  Aldosterone synthesis and secretion
hsa04960  Aldosterone-regulated sodium reabsorption
hsa04961  Endocrine and other factor-regulated calcium reabsorption
hsa04964  Proximal tubule bicarbonate reclamation
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion
hsa04973  Carbohydrate digestion and absorption
hsa04974  Protein digestion and absorption
hsa04976  Bile secretion
hsa04978  Mineral absorption
Disease
H00606  Early infantile epileptic encephalopathy
H00775  Hemiplegic migraine
H00998  Alternating hemiplegia of childhood
Drug target
Acetyldigitoxin: D06881
Acetyldigoxin: D07555
Bepridil (DG00333): D00631<JP> D07520
Bretylium tosilate: D00645
Deslanoside: D01240<JP>
Digitoxin: D00297
Digoxin: D00298<JP/US>
G-strophanthin: D00112
Gitoformate: D07147
Lanatoside C: D01972
Metildigoxin (DG00191): D02587<JP> D09847
Proscillaridin: D01379
beta-Acetyldigoxin: D07556
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    477 (ATP1A2)
   04022 cGMP-PKG signaling pathway
    477 (ATP1A2)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    477 (ATP1A2)
   04918 Thyroid hormone synthesis
    477 (ATP1A2)
   04919 Thyroid hormone signaling pathway
    477 (ATP1A2)
   04925 Aldosterone synthesis and secretion
    477 (ATP1A2)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    477 (ATP1A2)
   04261 Adrenergic signaling in cardiomyocytes
    477 (ATP1A2)
  09154 Digestive system
   04970 Salivary secretion
    477 (ATP1A2)
   04971 Gastric acid secretion
    477 (ATP1A2)
   04972 Pancreatic secretion
    477 (ATP1A2)
   04976 Bile secretion
    477 (ATP1A2)
   04973 Carbohydrate digestion and absorption
    477 (ATP1A2)
   04974 Protein digestion and absorption
    477 (ATP1A2)
   04978 Mineral absorption
    477 (ATP1A2)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    477 (ATP1A2)
   04961 Endocrine and other factor-regulated calcium reabsorption
    477 (ATP1A2)
   04964 Proximal tubule bicarbonate reclamation
    477 (ATP1A2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    477 (ATP1A2)
Enzymes [BR:hsa01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.13  Na+/K+-exchanging ATPase
     477 (ATP1A2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   477 (ATP1A2)
  Exosomal proteins of other body fluids (saliva and urine)
   477 (ATP1A2)
  Exosomal proteins of colorectal cancer cells
   477 (ATP1A2)
  Exosomal proteins of bladder cancer cells
   477 (ATP1A2)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Hydrolase Cation_ATPase_N Hydrolase_3
Other DBs
NCBI-GeneID: 477
NCBI-ProteinID: NP_000693
OMIM: 182340
HGNC: 800
Ensembl: ENSG00000018625
Pharos: P50993(Tclin)
UniProt: P50993 A0A0S2Z3W6
Position
1:160115759..160143591
AA seq 1020 aa
MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKG
LTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAME
DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINA
EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI
CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL
GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE
AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS
RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPF
NSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYM
ELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAV
GKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKAC
VVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSP
ALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN
IPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDK
LVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYG
QEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETA
LAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY
NT seq 3063 nt   +upstreamnt  +downstreamnt
atgggccgtggggctggccgtgagtactcacctgccgccaccacggcagagaatgggggc
ggcaagaagaaacagaaggagaaggaactggatgagctgaagaaggaggtggcaatggat
gaccacaagctgtccttggatgagctgggccgcaaataccaagtggacctgtccaagggc
ctcaccaaccagcgggctcaggacgttctggctcgagatgggcccaacgccctcacacca
cctcccacaacccctgagtgggtcaagttctgccgtcagcttttcggggggttctccatc
ctgctgtggattggggctatcctctgcttcctggcctacggcatccaggctgccatggag
gatgaaccatccaacgacaatctatatctgggtgtggtgctggcagctgtggtcattgtc
actggctgcttctcctactaccaggaggccaagagctccaagatcatggattccttcaag
aacatggtacctcagcaagcccttgtgatccgggagggagagaagatgcagatcaacgca
gaggaagtggtggtgggagacctggtggaggtgaagggtggagaccgcgtccctgctgac
ctccggatcatctcttctcatggctgtaaggtggataactcatccttaacaggagagtcg
gagccccagacccgctcccccgagttcacccatgagaaccccctggagacccgcaatatc
tgtttcttctccaccaactgtgttgaaggcactgccaggggcattgtgattgccacagga
gaccggacggtgatgggccgcatagctactctcgcctcaggcctggaggttgggcggaca
cccatagcaatggagattgaacacttcatccagctgatcacaggggtcgctgtattcctg
ggggtctccttcttcgtgctctccctcatcctgggctacagctggctggaggcagtcatc
ttcctcatcggcatcatagtggccaacgtgcctgaggggcttctggccactgtcactgtg
tgcctgaccctgacagccaagcgcatggcacggaagaactgcctggtgaagaacctggag
gcggtggagacgctgggctccacgtccaccatctgctcggacaagacgggcaccctcacc
cagaaccgcatgaccgtcgcccacatgtggttcgacaaccaaatccatgaggctgacacc
accgaagatcagtctggggccacttttgacaaacgatcccctacgtggacggccctgtct
cgaattgctggtctctgcaaccgcgccgtcttcaaggcaggacaggagaacatctccgtg
tctaagcgggacacagctggtgatgcctctgagtcagctctgctcaagtgcattgagctc
tcctgtggctcagtgaggaaaatgagagacagaaaccccaaggtggcagagattcctttc
aactctaccaacaagtaccagctgtctatccacgagcgagaagacagcccccagagccac
gtgctggtgatgaagggggccccagagcgcattctggaccggtgctccaccatcctggtg
cagggcaaggagatcccgctcgacaaggagatgcaagatgcctttcaaaatgcctacatg
gagctggggggacttggggagcgtgtgctgggattctgtcaactgaatctgccatctgga
aagtttcctcggggcttcaaattcgacacggatgagctgaactttcccacggagaagctt
tgctttgtggggctcatgtctatgattgaccctccccgggctgctgtgccagatgctgtg
ggcaagtgccgaagcgcaggcatcaaggtgatcatggtaaccggggatcaccctatcaca
gccaaggccattgccaaaggcgtgggcatcatatcagagggtaacgagactgtggaggac
attgcagcccggctcaacattcccatgagtcaagtcaaccccagagaagccaaggcatgc
gtggtgcacggctctgacctgaaggacatgacatcggagcagctcgatgagatcctcaag
aaccacacagagatcgtctttgctcgaacgtctccccagcagaagctcatcattgtggag
ggatgtcagaggcagggagccattgtggccgtgacgggtgacggggtgaacgactcccct
gcattgaagaaggctgacattggcattgccatgggcatctctggctctgacgtctctaag
caggcagccgacatgatcctgctggatgacaactttgcctccatcgtcacgggggtggag
gagggccgcctgatctttgacaacttgaagaaatccatcgcctacaccctgaccagcaac
atccccgagatcacccccttcctgctgttcatcattgccaacatccccctacctctgggc
actgtgaccatcctttgcattgacctgggcacagatatggtccctgccatctccttggcc
tatgaggcagctgagagtgatatcatgaagcggcagccacgaaactcccagacggacaag
ctggtgaatgagaggctcatcagcatggcctacggacagatcgggatgatccaggcactg
ggtggcttcttcacctactttgtgatcctggcagagaacggtttcctgccatcacggcta
ctgggaatccgcctcgactgggatgaccggaccatgaatgatctggaggacagctatgga
caggagtggacctatgagcagcggaaggtggtggagttcacgtgccacacggcattcttt
gccagcatcgtggtggtgcagtgggctgacctcatcatctgcaagacccgccgcaactca
gtcttccagcagggcatgaagaacaagatcctgatttttgggctcctggaggagacggcg
ttggctgcctttctctcttactgcccaggcatgggtgtagccctccgcatgtacccgctc
aaagtcacctggtggttctgcgccttcccctacagcctcctcatcttcatctatgatgag
gtccgaaagctcatcctgcggcggtatcctggtggctgggtggagaaggagacatactac
tga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (18)   
   KEGG PATHWAY (18)   
Disease (8)   
   KEGG DISEASE (3)   
   OMIM (5)   
Drug (15)   
   KEGG DRUG (15)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (45)   
   RefSeq(nuc) (3)   
   GenBank (21)   
   EMBL (21)   
Protein domain (6)   
   Pfam (6)   
All databases (121)   

Download RDF
KEGG   Homo sapiens (human): 478
Entry
478               CDS       T01001                                 
Symbol
ATP1A3, AHC2, ATP1A1, CAPOS, DEE99, DYT12, RDP
Name
(RefSeq) ATPase Na+/K+ transporting subunit alpha 3
  KO
K01539  sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04260  Cardiac muscle contraction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04911  Insulin secretion
hsa04918  Thyroid hormone synthesis
hsa04919  Thyroid hormone signaling pathway
hsa04925  Aldosterone synthesis and secretion
hsa04960  Aldosterone-regulated sodium reabsorption
hsa04961  Endocrine and other factor-regulated calcium reabsorption
hsa04964  Proximal tubule bicarbonate reclamation
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion
hsa04973  Carbohydrate digestion and absorption
hsa04974  Protein digestion and absorption
hsa04976  Bile secretion
hsa04978  Mineral absorption
Disease
H00606  Early infantile epileptic encephalopathy
H00831  Primary dystonia
H00998  Alternating hemiplegia of childhood
H02272  CAPOS syndrome
Drug target
Acetyldigitoxin: D06881
Acetyldigoxin: D07555
Bepridil (DG00333): D00631<JP> D07520
Bretylium tosilate: D00645
Deslanoside: D01240<JP>
Digitoxin: D00297
Digoxin: D00298<JP/US>
G-strophanthin: D00112
Gitoformate: D07147
Lanatoside C: D01972
Metildigoxin (DG00191): D02587<JP> D09847
Proscillaridin: D01379
beta-Acetyldigoxin: D07556
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    478 (ATP1A3)
   04022 cGMP-PKG signaling pathway
    478 (ATP1A3)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    478 (ATP1A3)
   04918 Thyroid hormone synthesis
    478 (ATP1A3)
   04919 Thyroid hormone signaling pathway
    478 (ATP1A3)
   04925 Aldosterone synthesis and secretion
    478 (ATP1A3)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    478 (ATP1A3)
   04261 Adrenergic signaling in cardiomyocytes
    478 (ATP1A3)
  09154 Digestive system
   04970 Salivary secretion
    478 (ATP1A3)
   04971 Gastric acid secretion
    478 (ATP1A3)
   04972 Pancreatic secretion
    478 (ATP1A3)
   04976 Bile secretion
    478 (ATP1A3)
   04973 Carbohydrate digestion and absorption
    478 (ATP1A3)
   04974 Protein digestion and absorption
    478 (ATP1A3)
   04978 Mineral absorption
    478 (ATP1A3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    478 (ATP1A3)
   04961 Endocrine and other factor-regulated calcium reabsorption
    478 (ATP1A3)
   04964 Proximal tubule bicarbonate reclamation
    478 (ATP1A3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    478 (ATP1A3)
Enzymes [BR:hsa01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.13  Na+/K+-exchanging ATPase
     478 (ATP1A3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   478 (ATP1A3)
  Exosomal proteins of other body fluids (saliva and urine)
   478 (ATP1A3)
  Exosomal proteins of colorectal cancer cells
   478 (ATP1A3)
  Exosomal proteins of bladder cancer cells
   478 (ATP1A3)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Hydrolase Cation_ATPase_N Hydrolase_3
Other DBs
NCBI-GeneID: 478
NCBI-ProteinID: NP_689509
OMIM: 182350
HGNC: 801
Ensembl: ENSG00000105409
Pharos: P13637(Tclin)
UniProt: P13637 Q53ES0
Structure
Position
19:complement(41966582..41994230)
AA seq 1013 aa
MGDKKDDKDSPKKNKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQE
ILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNL
YLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDL
VEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCV
EGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILS
LILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGST
STICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNR
AVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQL
SIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGE
RVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAG
IKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDL
KDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADI
GVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPF
LLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLI
SMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQ
RKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSY
CPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY
NT seq 3042 nt   +upstreamnt  +downstreamnt
atgggggacaagaaagatgacaaggactcacccaagaagaacaagggcaaggagcgccgg
gacctggatgacctcaagaaggaggtggctatgacagagcacaagatgtcagtggaagag
gtctgccggaaatacaacacagactgtgtgcagggtttgacccacagcaaagcccaggag
atcctggcccgggatgggcctaacgcactcacgccaccgcctaccaccccagagtgggtc
aagttttgccggcagctcttcgggggcttctccatcctgctgtggatcggggctatcctc
tgcttcctggcctacggtatccaggcgggcaccgaggacgacccctctggtgacaacctg
tacctgggcatcgtgctggcggccgtggtgatcatcactggctgcttctcctactaccag
gaggccaagagctccaagatcatggagtccttcaagaacatggtgccccagcaagccctg
gtgatccgggaaggtgagaagatgcaggtgaacgctgaggaggtggtggtcggggacctg
gtggagatcaagggtggagaccgagtgccagctgacctgcggatcatctcagcccacggc
tgcaaggtggacaactcctccctgactggcgaatccgagccccagactcgctctcccgac
tgcactcacgacaaccccttggagactcggaacatcaccttcttttccaccaactgtgtg
gaaggcacggctcggggcgtggtggtggccacgggcgaccgcactgtcatgggccgtatc
gccaccctggcatcagggctggaggtgggcaagacgcccatcgccatcgagattgagcac
ttcatccagctcatcaccggcgtggctgtcttcctgggtgtctccttcttcatcctctcc
ctcattctcggatacacctggcttgaggctgtcatcttcctcatcggcatcatcgtggcc
aatgtcccagagggtctgctggccactgtcactgtgtgtctgacgctgaccgccaagcgc
atggcccggaagaactgcctggtgaagaacctggaggctgtagaaaccctgggctccacg
tccaccatctgctcagataagacagggaccctcactcagaaccgcatgacagtcgcccac
atgtggtttgacaaccagatccacgaggctgacaccactgaggaccagtcagggacctca
tttgacaagagttcgcacacctgggtggccctgtctcacatcgctgggctctgcaatcgc
gctgtcttcaagggtggtcaggacaacatccctgtgctcaagagggatgtggctggggat
gcgtctgagtctgccctgctcaagtgcatcgagctgtcctctggctccgtgaagctgatg
cgtgaacgcaacaagaaagtggctgagattcccttcaattccaccaacaaataccagctc
tccatccatgagaccgaggaccccaacgacaaccgatacctgctggtgatgaagggtgcc
cccgagcgcatcctggaccgctgctccaccatcctgctacagggcaaggagcagcctctg
gacgaggaaatgaaggaggccttccagaatgcctaccttgagctcggtggcctgggcgag
cgcgtgcttggtttctgccattattacctgcccgaggagcagttccccaagggctttgcc
ttcgactgtgatgacgtgaacttcaccacggacaacctctgctttgtgggcctcatgtcc
atgatcgacccaccccgggcagccgtccctgacgcggtgggcaagtgtcgcagcgcaggc
atcaaggtcatcatggtcaccggcgatcaccccatcacggccaaggccattgccaagggt
gtgggcatcatctctgagggcaacgagactgtggaggacatcgccgcccggctcaacatt
cccgtcagccaggttaacccccgggatgccaaggcctgcgtgatccacggcaccgacctc
aaggacttcacctccgagcaaatcgacgagatcctgcagaatcacaccgagatcgtcttc
gcccgcacatccccccagcagaagctcatcattgtggagggctgtcagagacagggtgca
attgtggctgtgaccggggatggtgtgaacgactcccccgctctgaagaaggccgacatt
ggggtggccatgggcatcgctggctctgacgtctccaagcaggcagctgacatgatcctg
ctggacgacaactttgcctccatcgtcacaggggtggaggagggccgcctgatcttcgac
aacctaaagaagtccattgcctacaccctgaccagcaatatcccggagatcacgcccttc
ctgctgttcatcatggccaacatcccgctgcccctgggcaccatcaccatcctctgcatc
gatctgggcactgacatggtccctgccatctcactggcgtacgaggctgccgaaagcgac
atcatgaagagacagcccaggaacccgcggacggacaaattggtcaatgagagactcatc
agcatggcctacgggcagattggaatgatccaggctctcggtggcttcttctcttacttt
gtgatcctggcagaaaatggcttcttgcccggcaacctggtgggcatccggctgaactgg
gatgaccgcaccgtcaatgacctggaagacagttacgggcagcagtggacatacgagcag
aggaaggtggtggagttcacctgccacacggccttctttgtgagcatcgttgtcgtccag
tgggccgatctgatcatctgcaagacccggaggaactcggtcttccagcagggcatgaag
aacaagatcctgatcttcgggctgtttgaggagacggccctggctgccttcctgtcctac
tgccccggcatggacgtggccctgcgcatgtaccctctcaagcccagctggtggttctgt
gccttcccctacagtttcctcatcttcgtctacgacgaaatccgcaaactcatcctgcgc
aggaacccagggggttgggtggagaaggaaacctactactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (18)   
   KEGG PATHWAY (18)   
Disease (9)   
   KEGG DISEASE (4)   
   OMIM (5)   
Drug (15)   
   KEGG DRUG (15)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (40)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (16)   
   OC (1)   
   PHAROS (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (43)   
   RefSeq(nuc) (5)   
   GenBank (19)   
   EMBL (19)   
3D Structure (5)   
   PDB (5)   
Protein domain (6)   
   Pfam (6)   
All databases (149)   

Download RDF
KEGG   Homo sapiens (human): 480
Entry
480               CDS       T01001                                 
Symbol
ATP1A4, ATP1A1, ATP1AL2
Name
(RefSeq) ATPase Na+/K+ transporting subunit alpha 4
  KO
K01539  sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04260  Cardiac muscle contraction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04911  Insulin secretion
hsa04918  Thyroid hormone synthesis
hsa04919  Thyroid hormone signaling pathway
hsa04925  Aldosterone synthesis and secretion
hsa04960  Aldosterone-regulated sodium reabsorption
hsa04961  Endocrine and other factor-regulated calcium reabsorption
hsa04964  Proximal tubule bicarbonate reclamation
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion
hsa04973  Carbohydrate digestion and absorption
hsa04974  Protein digestion and absorption
hsa04976  Bile secretion
hsa04978  Mineral absorption
Drug target
Acetyldigitoxin: D06881
Acetyldigoxin: D07555
Bepridil (DG00333): D00631<JP> D07520
Bretylium tosilate: D00645
Deslanoside: D01240<JP>
Digitoxin: D00297
Digoxin: D00298<JP/US>
G-strophanthin: D00112
Gitoformate: D07147
Lanatoside C: D01972
Metildigoxin (DG00191): D02587<JP> D09847
Proscillaridin: D01379
beta-Acetyldigoxin: D07556
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    480 (ATP1A4)
   04022 cGMP-PKG signaling pathway
    480 (ATP1A4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    480 (ATP1A4)
   04918 Thyroid hormone synthesis
    480 (ATP1A4)
   04919 Thyroid hormone signaling pathway
    480 (ATP1A4)
   04925 Aldosterone synthesis and secretion
    480 (ATP1A4)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    480 (ATP1A4)
   04261 Adrenergic signaling in cardiomyocytes
    480 (ATP1A4)
  09154 Digestive system
   04970 Salivary secretion
    480 (ATP1A4)
   04971 Gastric acid secretion
    480 (ATP1A4)
   04972 Pancreatic secretion
    480 (ATP1A4)
   04976 Bile secretion
    480 (ATP1A4)
   04973 Carbohydrate digestion and absorption
    480 (ATP1A4)
   04974 Protein digestion and absorption
    480 (ATP1A4)
   04978 Mineral absorption
    480 (ATP1A4)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    480 (ATP1A4)
   04961 Endocrine and other factor-regulated calcium reabsorption
    480 (ATP1A4)
   04964 Proximal tubule bicarbonate reclamation
    480 (ATP1A4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    480 (ATP1A4)
Enzymes [BR:hsa01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.13  Na+/K+-exchanging ATPase
     480 (ATP1A4)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   480 (ATP1A4)
  Exosomal proteins of other body fluids (saliva and urine)
   480 (ATP1A4)
  Exosomal proteins of colorectal cancer cells
   480 (ATP1A4)
  Exosomal proteins of bladder cancer cells
   480 (ATP1A4)
SSDB
Motif
Pfam: Cation_ATPase_C E1-E2_ATPase Cation_ATPase Hydrolase Cation_ATPase_N Hydrolase_3 HAD DUF3213
Other DBs
NCBI-GeneID: 480
NCBI-ProteinID: NP_653300
OMIM: 607321
HGNC: 14073
Ensembl: ENSG00000132681
Pharos: Q13733(Tclin)
UniProt: Q13733
Position
1:160151603..160186980
AA seq 1029 aa
MGLWGKKGTVAPHDQSPRRRPKKGLIKKKMVKREKQKRNMEELKKEVVMDDHKLTLEELS
TKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLLLWTGAILCF
VAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFKNMVPQQALVI
RGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFT
HENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFI
HLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGIIVANVPEGLLATVTVCLTLTAKRMA
RKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEADTTEEQTGKTFT
KSSDTWFMLARIAGLCNRADFKANQEILPIAKRATTGDASESALLKFIEQSYSSVAEMRE
KNPKVAEIPFNSTNKYQMSIHLREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSMNDE
MKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDP
PRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAARLKIPISK
VDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQQKLIIVEGCQRLGAVVAV
TGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKK
SIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKR
LPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVILAENGFRPVDLLGIRLHWEDKY
LNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVVVQWADLIISKTRRNSLFQQGMRNKVL
IFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPD
GWVERETYY
NT seq 3090 nt   +upstreamnt  +downstreamnt
atggggctttgggggaagaaagggacagtggctccccatgaccagagtccaagacgaaga
cctaaaaaagggcttatcaagaaaaaaatggtgaagagggaaaaacagaagcgcaatatg
gaggaactgaagaaggaagtggtcatggatgatcacaaattaaccttggaagagctgagc
accaagtactccgtggacctgacaaagggccatagccaccaaagggcaaaggaaatcctg
actcgaggtggacccaatactgttaccccaccccccaccactccagaatgggtcaaattc
tgtaagcaactgttcggaggcttctccctcctactatggactggggccattctctgcttt
gtggcctacagcatccagatatatttcaatgaggagcctaccaaagacaacctctacctg
agcatcgtactgtccgtcgtggtcatcgtcactggctgcttctcctattatcaggaggcc
aagagctccaagatcatggagtcttttaagaacatggtgcctcagcaagctctggtaatt
cgaggaggagagaagatgcaaattaatgtacaagaggtggtgttgggagacctggtggaa
atcaagggtggagaccgagtccctgctgacctccggcttatctctgcacaaggatgtaag
gtggacaactcatccttgactggggagtcagaaccccagagccgctcccctgacttcacc
catgagaaccctctggagacccgaaacatctgcttcttttccaccaactgtgtggaagga
accgcccggggtattgtgattgctacgggagactccacagtgatgggcagaattgcctcc
ctgacgtcaggcctggcggttggccagacacctatcgctgctgagatcgaacacttcatc
catctgatcactgtggtggccgtcttccttggtgtcactttttttgcgctctcacttctc
ttgggctatggttggctggaggctatcatttttctcattggcatcattgtggccaatgtg
cctgaggggctgttggccacagtcactgtgtgcctgaccctcacagccaagcgcatggcg
cggaagaactgcctggtgaagaacctggaggcggtggagacgctgggctccacgtccacc
atctgctcagacaagacgggcaccctcacccagaaccgcatgaccgtcgcccacatgtgg
tttgatatgaccgtgtatgaggccgacaccactgaagaacagactggaaaaacatttacc
aagagctctgatacctggtttatgctggcccgaatcgctggcctctgcaaccgggctgac
tttaaggctaatcaggagatcctgcccattgctaagagggccacaacaggtgatgcttcc
gagtcagccctcctcaagttcatcgagcagtcttacagctctgtggcggagatgagagag
aaaaaccccaaggtggcagagattccctttaattctaccaacaagtaccagatgtccatc
caccttcgggaggacagctcccagacccacgtactgatgatgaagggtgctccggagagg
atcttggagttttgttctacctttcttctgaatgggcaggagtactcaatgaacgatgaa
atgaaggaagccttccaaaatgcctacttagaactgggaggtctgggggaacgtgtgcta
ggcttctgcttcttgaatctgcctagcagcttctccaagggattcccatttaatacagat
gaaataaatttccccatggacaacctttgttttgtgggcctcatatccatgattgaccct
ccccgagctgcagtgcctgatgctgtgagcaagtgtcgcagtgcaggaattaaggtgatc
atggtaacaggagatcatcccattacagctaaggccattgccaagggtgtgggcatcatc
tcagaaggcactgagacggcagaggaagtcgctgcccggcttaagatccctatcagcaag
gtcgatgccagtgctgccaaagccattgtggtgcatggtgcagaactgaaggacatacag
tccaagcagcttgatcagatcctccagaaccaccctgagatcgtgtttgctcggacctcc
cctcagcagaagctcatcattgtcgagggatgtcagaggctgggagccgttgtggccgtg
acaggtgacggggtgaacgactcccctgcgctgaagaaggctgacattggcattgccatg
ggcatctctggctctgacgtctctaagcaggcagccgacatgatcctgctggatgacaac
tttgcctccatcgtcacgggggtggaggagggccgcctgatctttgacaacctgaagaaa
tccatcatgtacaccctgaccagcaacatccccgagatcacgcccttcctgatgttcatc
atcctcggtatacccctgcctctgggaaccataaccatcctctgcattgatctcggcact
gacatggtccctgccatctccttggcttatgagtcagctgaaagcgacatcatgaagagg
cttccaaggaacccaaagacggataatctggtgaaccaccgtctcattggcatggcctat
ggacagattgggatgatccaggctctggctggattctttacctactttgtaatcctggct
gagaatggttttaggcctgttgatctgctgggcatccgcctccactgggaagataaatac
ttgaatgacctggaggacagctacggacagcagtggacctatgagcaacgaaaagttgtg
gagttcacatgccaaacggccttttttgtcaccatcgtggttgtgcagtgggcggatctc
atcatctccaagactcgccgcaactcacttttccagcagggcatgagaaacaaagtctta
atatttgggatcctggaggagacactcttggctgcatttctgtcctacactccaggcatg
gacgtggccctgcgaatgtacccactcaagataacctggtggctctgtgccattccctac
agtattctcatcttcgtctatgatgaaatcagaaaactcctcatccgtcagcacccggat
ggctgggtggaaagggagacgtactactaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (18)   
   KEGG PATHWAY (18)   
Disease (1)   
   OMIM (1)   
Drug (15)   
   KEGG DRUG (15)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (28)   
   RefSeq(nuc) (4)   
   GenBank (12)   
   EMBL (12)   
Protein domain (8)   
   Pfam (8)   
All databases (104)   

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KEGG   Homo sapiens (human): 481
Entry
481               CDS       T01001                                 
Symbol
ATP1B1, ATP1B
Name
(RefSeq) ATPase Na+/K+ transporting subunit beta 1
  KO
K01540  sodium/potassium-transporting ATPase subunit beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04260  Cardiac muscle contraction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04911  Insulin secretion
hsa04918  Thyroid hormone synthesis
hsa04919  Thyroid hormone signaling pathway
hsa04925  Aldosterone synthesis and secretion
hsa04960  Aldosterone-regulated sodium reabsorption
hsa04961  Endocrine and other factor-regulated calcium reabsorption
hsa04964  Proximal tubule bicarbonate reclamation
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion
hsa04973  Carbohydrate digestion and absorption
hsa04974  Protein digestion and absorption
hsa04976  Bile secretion
hsa04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    481 (ATP1B1)
   04022 cGMP-PKG signaling pathway
    481 (ATP1B1)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    481 (ATP1B1)
   04918 Thyroid hormone synthesis
    481 (ATP1B1)
   04919 Thyroid hormone signaling pathway
    481 (ATP1B1)
   04925 Aldosterone synthesis and secretion
    481 (ATP1B1)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    481 (ATP1B1)
   04261 Adrenergic signaling in cardiomyocytes
    481 (ATP1B1)
  09154 Digestive system
   04970 Salivary secretion
    481 (ATP1B1)
   04971 Gastric acid secretion
    481 (ATP1B1)
   04972 Pancreatic secretion
    481 (ATP1B1)
   04976 Bile secretion
    481 (ATP1B1)
   04973 Carbohydrate digestion and absorption
    481 (ATP1B1)
   04974 Protein digestion and absorption
    481 (ATP1B1)
   04978 Mineral absorption
    481 (ATP1B1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    481 (ATP1B1)
   04961 Endocrine and other factor-regulated calcium reabsorption
    481 (ATP1B1)
   04964 Proximal tubule bicarbonate reclamation
    481 (ATP1B1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    481 (ATP1B1)
CD molecules [BR:hsa04090]
 Proteins
  481 (ATP1B1)
SSDB
Motif
Pfam: Na_K-ATPase
Other DBs
NCBI-GeneID: 481
NCBI-ProteinID: NP_001668
OMIM: 182330
HGNC: 804
Ensembl: ENSG00000143153
Pharos: P05026(Tclin)
UniProt: P05026 A3KLL5
Structure
Position
1:169106690..169132719
AA seq 303 aa
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLT
ISEFKPTYQDRVAPPGLTQIPQIQKTEISFRPNDPKSYEAYVLNIVRFLEKYKDSAQRDD
MIFEDCGDVPSEPKERGDFNHERGERKVCRFKLEWLGNCSGLNDETYGYKEGKPCIIIKL
NRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGKRDEDKDKVGNVEYFGLGNSPGFPL
QYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGYSEKDRFQGRFDVKIE
VKS
NT seq 912 nt   +upstreamnt  +downstreamnt
atggcccgcgggaaagccaaggaggagggcagctggaagaaattcatctggaactcagag
aagaaggagtttctgggcaggaccggtggcagttggtttaagatccttctattctacgta
atattttatggctgcctggctggcatcttcatcggaaccatccaagtgatgctgctcacc
atcagtgaatttaagcccacatatcaggaccgagtggccccgccaggattaacacagatt
cctcagatccagaagactgaaatttcctttcgtcctaatgatcccaagagctatgaggca
tatgtactgaacatagttaggttcctggaaaagtacaaagattcagcccagagggatgac
atgatttttgaagattgtggcgatgtgcccagtgaaccgaaagaacgaggagactttaat
catgaacgaggagagcgaaaggtctgcagattcaagcttgaatggctgggaaattgctct
ggattaaatgatgaaacttatggctacaaagagggcaaaccgtgcattattataaagctc
aaccgagttctaggcttcaaacctaagcctcccaagaatgagtccttggagacttaccca
gtgatgaagtataacccaaatgtccttcccgttcagtgcactggcaagcgagatgaagat
aaggataaagttggaaatgtggagtattttggactgggcaactcccctggttttcctctg
cagtattatccgtactatggcaaactcctgcagcccaaatacctgcagcccctgctggcc
gtacagttcaccaatcttaccatggacactgaaattcgcatagagtgtaaggcgtacggt
gagaacattgggtacagtgagaaagaccgttttcagggacgttttgatgtaaaaattgaa
gttaagagctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (18)   
   KEGG PATHWAY (18)   
Disease (2)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (11)   
   OC (1)   
   PHAROS (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (38)   
   RefSeq(nuc) (2)   
   GenBank (18)   
   EMBL (18)   
3D Structure (8)   
   PDB (8)   
Protein domain (1)   
   Pfam (1)   
All databases (95)   

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KEGG   Homo sapiens (human): 482
Entry
482               CDS       T01001                                 
Symbol
ATP1B2, AMOG
Name
(RefSeq) ATPase Na+/K+ transporting subunit beta 2
  KO
K01540  sodium/potassium-transporting ATPase subunit beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04260  Cardiac muscle contraction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04911  Insulin secretion
hsa04918  Thyroid hormone synthesis
hsa04919  Thyroid hormone signaling pathway
hsa04925  Aldosterone synthesis and secretion
hsa04960  Aldosterone-regulated sodium reabsorption
hsa04961  Endocrine and other factor-regulated calcium reabsorption
hsa04964  Proximal tubule bicarbonate reclamation
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion
hsa04973  Carbohydrate digestion and absorption
hsa04974  Protein digestion and absorption
hsa04976  Bile secretion
hsa04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    482 (ATP1B2)
   04022 cGMP-PKG signaling pathway
    482 (ATP1B2)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    482 (ATP1B2)
   04918 Thyroid hormone synthesis
    482 (ATP1B2)
   04919 Thyroid hormone signaling pathway
    482 (ATP1B2)
   04925 Aldosterone synthesis and secretion
    482 (ATP1B2)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    482 (ATP1B2)
   04261 Adrenergic signaling in cardiomyocytes
    482 (ATP1B2)
  09154 Digestive system
   04970 Salivary secretion
    482 (ATP1B2)
   04971 Gastric acid secretion
    482 (ATP1B2)
   04972 Pancreatic secretion
    482 (ATP1B2)
   04976 Bile secretion
    482 (ATP1B2)
   04973 Carbohydrate digestion and absorption
    482 (ATP1B2)
   04974 Protein digestion and absorption
    482 (ATP1B2)
   04978 Mineral absorption
    482 (ATP1B2)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    482 (ATP1B2)
   04961 Endocrine and other factor-regulated calcium reabsorption
    482 (ATP1B2)
   04964 Proximal tubule bicarbonate reclamation
    482 (ATP1B2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    482 (ATP1B2)
CD molecules [BR:hsa04090]
 Proteins
  482 (ATP1B2)
SSDB
Motif
Pfam: Na_K-ATPase
Other DBs
NCBI-GeneID: 482
NCBI-ProteinID: NP_001669
OMIM: 182331
HGNC: 805
Ensembl: ENSG00000129244
Pharos: P14415(Tclin)
UniProt: P14415
Position
17:7646627..7657770
AA seq 290 aa
MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW
VMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDS
IQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFI
KMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVNYT
QPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT
NT seq 873 nt   +upstreamnt  +downstreamnt
atggtcatccagaaagagaagaagagctgcgggcaggtggttgaggagtggaaggagttc
gtgtggaacccgaggacgcaccagtttatgggccgcaccgggaccagctgggcctttatc
ctcctcttctacctcgttttttatgggttcctcaccgccatgttcaccctcaccatgtgg
gtgatgctgcagactgtctccgaccatacccccaagtaccaggaccgactggccacaccg
ggcttgatgattcgccccaagactgagaaccttgatgtcattgtcaatgtcagtgacact
gaaagctgggaccagcatgttcagaagctcaacaagttcttggagccttacaacgactct
atccaagcccaaaagaatgatgtctgccgccctggacgctattacgaacagccagataat
ggagtcctcaactaccccaaacgtgcctgccaattcaaccggacccagctgggcaactgc
tccggcattggggactccacccactatggttacagcactgggcagccctgtgtcttcatc
aagatgaaccgggtcatcaacttctatgcaggagcaaaccagagcatgaatgttacctgt
gctgggaagcgagatgaagatgctgagaatctcggcaacttcgtcatgttccccgccaac
ggcaacatcgacctcatgtacttcccctactatggcaaaaagttccacgtgaactacaca
cagcccctggtggctgtgaagttcctgaatgtgacccccaacgtggaggtgaatgtagaa
tgtcgcatcaacgccgccaacatcgccacagacgatgagcgagacaagttcgccggccgc
gtggccttcaaactccgcatcaacaaaacctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (18)   
   KEGG PATHWAY (18)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (36)   
   RefSeq(nuc) (2)   
   GenBank (17)   
   EMBL (17)   
Protein domain (1)   
   Pfam (1)   
All databases (74)   

Download RDF
KEGG   Homo sapiens (human): 483
Entry
483               CDS       T01001                                 
Symbol
ATP1B3, ATPB-3, CD298
Name
(RefSeq) ATPase Na+/K+ transporting subunit beta 3
  KO
K01540  sodium/potassium-transporting ATPase subunit beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04260  Cardiac muscle contraction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04911  Insulin secretion
hsa04918  Thyroid hormone synthesis
hsa04919  Thyroid hormone signaling pathway
hsa04925  Aldosterone synthesis and secretion
hsa04960  Aldosterone-regulated sodium reabsorption
hsa04961  Endocrine and other factor-regulated calcium reabsorption
hsa04964  Proximal tubule bicarbonate reclamation
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion
hsa04973  Carbohydrate digestion and absorption
hsa04974  Protein digestion and absorption
hsa04976  Bile secretion
hsa04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    483 (ATP1B3)
   04022 cGMP-PKG signaling pathway
    483 (ATP1B3)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    483 (ATP1B3)
   04918 Thyroid hormone synthesis
    483 (ATP1B3)
   04919 Thyroid hormone signaling pathway
    483 (ATP1B3)
   04925 Aldosterone synthesis and secretion
    483 (ATP1B3)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    483 (ATP1B3)
   04261 Adrenergic signaling in cardiomyocytes
    483 (ATP1B3)
  09154 Digestive system
   04970 Salivary secretion
    483 (ATP1B3)
   04971 Gastric acid secretion
    483 (ATP1B3)
   04972 Pancreatic secretion
    483 (ATP1B3)
   04976 Bile secretion
    483 (ATP1B3)
   04973 Carbohydrate digestion and absorption
    483 (ATP1B3)
   04974 Protein digestion and absorption
    483 (ATP1B3)
   04978 Mineral absorption
    483 (ATP1B3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    483 (ATP1B3)
   04961 Endocrine and other factor-regulated calcium reabsorption
    483 (ATP1B3)
   04964 Proximal tubule bicarbonate reclamation
    483 (ATP1B3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    483 (ATP1B3)
CD molecules [BR:hsa04090]
 Proteins
  483 (ATP1B3)
SSDB
Motif
Pfam: Na_K-ATPase
Other DBs
NCBI-GeneID: 483
NCBI-ProteinID: NP_001670
OMIM: 601867
HGNC: 806
Ensembl: ENSG00000069849
Pharos: P54709(Tclin)
UniProt: P54709
Position
3:141876643..141926549
AA seq 279 aa
MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWV
MLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLE
EQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIG
LKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPN
NTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA
NT seq 840 nt   +upstreamnt  +downstreamnt
atgacgaagaacgagaagaagtccctcaaccagagcctggccgagtggaagctcttcatc
tacaacccgaccaccggagaattcctggggcgcaccgccaagagctggggtttgatcttg
ctcttctacctagttttttatgggttcctggctgcactcttctcattcacgatgtgggtt
atgcttcagactctcaacgatgaggttccaaaataccgtgaccagattcctagcccagga
ctcatggtttttccaaaaccagtgaccgcattggaatatacattcagtaggtctgatcca
acttcgtatgcagggtacattgaagaccttaagaagtttctaaaaccatatactttagaa
gaacagaagaacctcacagtctgtcctgatggagcactttttgaacagaagggtccagtt
tatgttgcatgtcagtttcctatttcattacttcaagcatgcagtggtatgaatgatcct
gattttggctattctcaaggaaacccttgtattcttgtgaaaatgaacagaataattgga
ttaaagcctgaaggagtgccaaggatagattgtgtttcaaagaatgaagatataccaaat
gtagcagtttatcctcataatggaatgatagacttaaaatatttcccatattatgggaaa
aaactgcatgttgggtatctacagccattggttgctgttcaggtcagctttgctcctaac
aacactgggaaagaagtaacagttgagtgcaagattgatggatcagccaacctaaaaagt
caggatgatcgtgacaagtttttgggacgagttatgttcaaaatcacagcacgtgcatag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (18)   
   KEGG PATHWAY (18)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
   PHAROS (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (23)   
   RefSeq(nuc) (1)   
   GenBank (11)   
   EMBL (11)   
Protein domain (1)   
   Pfam (1)   
All databases (65)   

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KEGG   Homo sapiens (human): 486
Entry
486               CDS       T01001                                 
Symbol
FXYD2, ATP1G1, HOMG2
Name
(RefSeq) FXYD domain containing ion transport regulator 2
  KO
K01538  sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04260  Cardiac muscle contraction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04911  Insulin secretion
hsa04918  Thyroid hormone synthesis
hsa04919  Thyroid hormone signaling pathway
hsa04960  Aldosterone-regulated sodium reabsorption
hsa04961  Endocrine and other factor-regulated calcium reabsorption
hsa04964  Proximal tubule bicarbonate reclamation
hsa04970  Salivary secretion
hsa04972  Pancreatic secretion
hsa04973  Carbohydrate digestion and absorption
hsa04974  Protein digestion and absorption
hsa04976  Bile secretion
hsa04978  Mineral absorption
Disease
H01210  Hypomagnesemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    486 (FXYD2)
   04022 cGMP-PKG signaling pathway
    486 (FXYD2)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    486 (FXYD2)
   04918 Thyroid hormone synthesis
    486 (FXYD2)
   04919 Thyroid hormone signaling pathway
    486 (FXYD2)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    486 (FXYD2)
   04261 Adrenergic signaling in cardiomyocytes
    486 (FXYD2)
  09154 Digestive system
   04970 Salivary secretion
    486 (FXYD2)
   04972 Pancreatic secretion
    486 (FXYD2)
   04976 Bile secretion
    486 (FXYD2)
   04973 Carbohydrate digestion and absorption
    486 (FXYD2)
   04974 Protein digestion and absorption
    486 (FXYD2)
   04978 Mineral absorption
    486 (FXYD2)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    486 (FXYD2)
   04961 Endocrine and other factor-regulated calcium reabsorption
    486 (FXYD2)
   04964 Proximal tubule bicarbonate reclamation
    486 (FXYD2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    486 (FXYD2)
   04147 Exosome [BR:hsa04147]
    486 (FXYD2)
Transporters [BR:hsa02000]
 Other transporters
  Pores ion channels [TC:1]
   486 (FXYD2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   486 (FXYD2)
SSDB
Motif
Pfam: ATP1G1_PLM_MAT8
Other DBs
NCBI-GeneID: 486
NCBI-ProteinID: NP_001671
OMIM: 601814
HGNC: 4026
Ensembl: ENSG00000137731
Pharos: P54710(Tclin)
UniProt: P54710
Structure
Position
11:complement(117820057..117828089)
AA seq 66 aa
MTGLSMDGGGSPKGDVDPFYYDYETVRNGGLIFAGLAFIVGLLILLSRRFRCGGNKKRRQ
INEDEP
NT seq 201 nt   +upstreamnt  +downstreamnt
atgactgggttgtcgatggacggtggcggcagccccaagggggacgtggacccgttctac
tatgactatgagaccgttcgcaatgggggcctgatcttcgctggactggccttcatcgtg
gggctcctcatcctcctcagcagaagattccgctgtgggggcaataagaagcgcaggcaa
atcaatgaagatgagccgtaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (16)   
   KEGG PATHWAY (16)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (25)   
   RefSeq(nuc) (3)   
   GenBank (11)   
   EMBL (11)   
3D Structure (4)   
   PDB (4)   
Protein domain (1)   
   Pfam (1)   
All databases (72)   

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