KEGG   Homo sapiens (human): 252969
Entry
252969            CDS       T01001                                 
Symbol
NEIL2, NEH2, NEI2
Name
(RefSeq) endonuclease 8-like 2 isoform a
  KO
K10568  endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03410  Base excision repair
Network
nt06504  Base excision repair
  Element
N01435  Base excision and strand cleavage by NEIL glycosylase
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03410 Base excision repair
    252969 (NEIL2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    252969 (NEIL2)
Enzymes [BR:hsa01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.99  Other carbon-oxygen lyases
    4.2.99.18  DNA-(apurinic or apyrimidinic site) lyase
     252969 (NEIL2)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA glycosylases
     252969 (NEIL2)
SSDB
Motif
Pfam: H2TH zf-FPG_IleRS
Other DBs
NCBI-GeneID: 252969
NCBI-ProteinID: NP_001129218
OMIM: 608933
HGNC: 18956
UniProt: Q969S2
Position
8:11769710..11787345
AA seq 332 aa
MPEGPLVRKFHHLVSPFVGQQVVKTGGSSKKLQPASLQSLWLQDTQVHGKKLFLRFDLDE
EMGPPGSSPTPEPPQKEVQKEGAADPKQVGEPSGQKTLDGSSRSAELVPQGEDDSEYLER
DAPAGDAGRWLRVSFGLFGSVWVNDFSRAKKANKRGDWRDPSPRLVLHFGGGGFLAFYNC
QLSWSSSPVVTPTCDILSEKFHRGQALEALGQAQPVCYTLLDQRYFSGLGNIIKNEALYR
AGIHPLSLGSVLSASRREVLVDHVVEFSTAWLQGKFQGRPQHTQVYQKEQCPAGHQVMKE
AFGPEDGLQRLTWWCPQCQPQLSEEPEQCQFS
NT seq 999 nt   +upstreamnt  +downstreamnt
atgccagaagggccgttggtgaggaaatttcaccatttggtctccccctttgtgggtcag
caggtggtcaagacagggggcagcagtaagaagctacagcccgccagcctgcagtctctg
tggctccaggacacccaggtccatggaaagaaattattccttagatttgatctagatgaa
gaaatggggccccctggcagcagcccaacaccagagcctccacaaaaagaagtgcagaag
gaaggggctgcggacccaaagcaggtcggggagcccagcgggcagaagacccttgatgga
tcctcacggtctgcagagctcgtcccccagggcgaggatgattctgagtatttggagaga
gacgcccctgcaggagatgctgggaggtggctgcgtgtcagctttggtttgtttggcagc
gtttgggtgaacgatttctccagagccaagaaagccaacaagaggggggactggagggac
ccttccccgaggttggtcctgcactttggtggtggtggcttcctggcattttataattgt
cagttgtcttggagctcttccccagtggtcacacccacctgtgacatcctgtctgagaag
ttccatcgaggacaagccttagaagctctaggccaggctcagcctgtctgctatacactg
ctggaccagagatacttctcagggctagggaacatcattaagaatgaagccttgtacaga
gctgggatccatcccctttctctcggttcagtcctgagtgcctcgcgtcgggaggtcctg
gtggatcacgtggtggagttcagtacagcctggctgcagggcaagttccaaggcagaccg
cagcacacacaggtctaccagaaagaacagtgccctgctggccaccaggtcatgaaggag
gcgtttgggcccgaagatgggttacagaggctcacctggtggtgcccgcagtgccagccc
cagttgtcagaggagccagagcagtgccagttctcctaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (13)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (37)   
   RefSeq(nuc) (11)   
   GenBank (13)   
   EMBL (13)   
Protein domain (2)   
   Pfam (2)   
All databases (63)   

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