KEGG   Homo sapiens (human): 3758
Entry
3758              CDS       T01001                                 
Symbol
KCNJ1, KIR1.1, ROMK, ROMK1
Name
(RefSeq) ATP-sensitive inward rectifier potassium channel 1 isoform a
  KO
K04995  potassium inwardly-rectifying channel subfamily J member 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04960  Aldosterone-regulated sodium reabsorption
hsa04971  Gastric acid secretion
Disease
H00239  Bartter syndrome
Drug target
Betanidine: D01603
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04971 Gastric acid secretion
    3758 (KCNJ1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    3758 (KCNJ1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    3758 (KCNJ1)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Potassium channel, inwardly-rectifying (Kir)
   3758 (KCNJ1)
SSDB
Motif
Pfam: IRK_C IRK
Other DBs
NCBI-GeneID: 3758
NCBI-ProteinID: NP_000211
OMIM: 600359
HGNC: 6255
UniProt: P48048 A8K432
Position
11:complement(128838020..128867296)
AA seq 391 aa
MNASSRNVFDTLIRVLTESMFKHLRKWVVTRFFGHSRQRARLVSKDGRCNIEFGNVEAQS
RFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFGLLWYAVAYIHKDLPEFHPSANHTP
CVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATAIFLLIFQSILGVIINSFMCGAILA
KISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANLRKSLLIGSHIYGKLLKTTVTPEGE
TIILDQININFVVDAGNENLFFISPLTIYHVIDHNSPFFHMAAETLLQQDFELVVFLDGT
VESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGKYRVDFHNFSKTVEVETPHCAMCLY
NEKDVRARMKRGYDNPNFILSEVNETDDTKM
NT seq 1176 nt   +upstreamnt  +downstreamnt
atgaatgcttccagtcggaatgtgtttgacacgttgatcagggtgttgacagaaagtatg
ttcaaacatcttcggaaatgggtcgtcactcgcttttttgggcattctcggcaaagagca
aggctagtctccaaagatggaaggtgcaacatagaatttggcaatgtggaggcacagtca
aggtttatattctttgtggacatctggacaacggtacttgacctcaagtggagatacaaa
atgaccattttcatcacagccttcttggggagttggtttttctttggtctcctgtggtat
gcagtagcgtacattcacaaagacctcccggaattccatccttctgccaatcacactccc
tgtgtggagaatattaatggcttgacctcagcttttctgttttctctggagactcaagtg
accattggatatggattcaggtgtgtgacagaacagtgtgccactgccatttttctgctt
atctttcagtctatacttggagttataatcaattctttcatgtgtggggccatcttagcc
aagatctccaggcccaaaaaacgtgccaagaccattacgttcagcaagaacgcagtgatc
agcaaacggggagggaagctttgcctcctaatccgagtggctaatctcaggaagagcctt
cttattggcagtcacatttatggaaagcttctgaagaccacagtcactcctgaaggagag
accattattttggaccagatcaatatcaactttgtagttgacgctgggaatgaaaattta
ttcttcatctccccattgacaatttaccatgtcattgatcacaacagccctttcttccac
atggcagcggagacccttctccagcaggactttgaattagtggtgtttttagatggcaca
gtggagtccaccagtgctacctgccaagtccggacatcctatgtcccagaggaggtgctt
tggggctaccgttttgctcccatagtatccaagacaaaggaagggaaataccgagtggat
ttccataactttagcaagacagtggaagtggagacccctcactgtgccatgtgcctttat
aatgagaaagatgttagagccaggatgaagagaggctatgacaaccccaacttcatcttg
tcagaagtcaatgaaacagatgacaccaaaatgtaa

  All links  
Disease (2)   
   OMIM (2)   
Gene (7)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (47)   
   RefSeq(nuc) (5)   
   GenBank (21)   
   EMBL (21)   
Protein domain (2)   
   Pfam (2)   
All databases (66)   

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