KEGG   Homo sapiens (human): 57703
Entry
57703             CDS       T01001                                 
Symbol
CWC22, EIF4GL, NCM, fSAPb
Name
(RefSeq) pre-mRNA-splicing factor CWC22 homolog isoform a
  KO
K13100  pre-mRNA-splicing factor CWC22
Organism
hsa  Homo sapiens (human)
Network
nt06547  Spliceosome
  Element
N01971  spliceosome activation
N01972  Spliceosome catalysis (branching)
N01993  Spliceosome catalysis (exon ligation)
N01994  Spliceosome disassembly
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    57703 (CWC22)
Spliceosome [BR:hsa03041]
 Complex B
  U4/U6.U5 tri-snRNP components
   U4/U6.U5 tri-snRNP related factors
    57703 (CWC22)
 Complex C
   U4/U6.U5 tri-SnRNP related factors
    57703 (CWC22)
SSDB
Motif
Pfam: MA3 MIF4G Cnd1
Other DBs
NCBI-GeneID: 57703
NCBI-ProteinID: NP_001362958
OMIM: 615186
HGNC: 29322
UniProt: Q9HCG8
Structure
Position
2:complement(179944876..180007297)
AA seq 908 aa
MKSSVAQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGR
SYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD
ELDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNISI
IIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILN
FRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKEC
GLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPIILEGLDLV
EEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDTDSNTDQDAG
SSEEDEEEEEEEGEEDEEGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKME
FPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFEGIFKEQYDTIHRLE
TNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLN
ARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPD
VEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKK
GHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDP
ITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRI
KDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRR
EKSPAKQK
NT seq 2727 nt   +upstreamnt  +downstreamnt
atgaaaagtagtgtggcacagataaaaccttcttctggtcatgacagaagggaaaacctt
aattcatatcagaggaactcctctccagaagacagatatgaagaacaagaacgatccccc
cgggatagagattactttgattacagcagatcagactatgagcattcaagaagaggacgt
tcttatgatagtagcatggagtcacgaaacagggaccgagaaaaacgcagagaaagagaa
agagatacggatcggaaaaggtctcggaaatccccatctcctgggaggagaaacccagaa
acatcagtaactcagagttcctctgctcaggatgaacctgctacaaagaaaaagaaagat
gagctggatcctcttcttactcgcactggtggagcatatattccccctgcaaagctcagg
atgatgcaggaacagattacagataaaaacagcttagcataccagaggatgagttgggag
gccctgaagaagtcaattaatggccttatcaacaaagtcaacatttccaacataagtatt
attattcaagagcttcttcaagaaaatatagttagaggaagaggactgctgtccaggtct
gttttgcaagcacagagtgcttctccaatcttcacccatgtttatgcagcattagtggca
attatcaactcaaaatttccacaaattggagaattaatcctcaaaaggttaattcttaat
tttcgaaaaggctatcgaagaaatgacaagcaactttgcctgactgcttcaaaatttgtg
gcgcatcttattaaccaaaatgtggcacacgaagtattatgcttagagatgctcactttg
ctcctggaaagaccaacagatgatagcgttgaagtagctattggttttcttaaggaatgt
ggcctcaaattaacacaagtgtcaccaagaggaatcaatgctatatttgaacgccttcga
aacattctgcatgagtctgaaattgacaaaagagttcaatatatgattgaagtgatgttt
gctgtacggaaagatggattcaaggaccaccccattatcctagaaggtcttgatttggtg
gaagaagatgatcaattcactcatatgctccctctggaggatgactataatccagaagat
gttcttaatgttttcaagatggatcctaattttatggagaatgaagagaagtacaaagct
attaagaaagaaattcttgatgagggagatactgactcgaacacagaccaggatgctggg
agtagtgaagaggacgaggaagaagaagaggaagagggagaagaagatgaagaaggacaa
aaagtaactattcatgacaaaacagaaattaacctggtctcatttcgtcgtacaatttat
cttgctattcagtcaagtttagattttgaagaatgtgctcacaaattgctgaaaatggag
tttcctgaaagccaaacaaaagaactctgcaacatgatacttgattgctgtgcccaacag
aggacatacgaaaaattttttggcttattagctgggcgattttgcatgctaaagaaagag
tacatggaatcctttgaaggtatattcaaagaacagtatgataccatccatcgcttggaa
acaaacaagttgcgaaatgttgctaagatgtttgctcaccttttatacactgattcactt
ccatggagtgttcttgaatgtataaaactgagtgaagaaaccactacatcatccagtaga
atttttgtcaaaatatttttccaggaactgtgtgaatacatgggtcttcctaaacttaat
gcaagattaaaggatgaaactctgcagccattctttgaaggattattaccccgagataat
ccaagaaacactcggtttgccatcaacttctttacttctataggtcttggaggtttaacg
gatgaactgcgggagcatctcaaaaatacaccaaaggtcattgtggcgcagaaaccagat
gttgagcaaaataaatcctccccatcctcttcctcttcagcgtcctcctcttcagagtct
gactcatccgactctgattctgacagcagtgatagcagttcagagtcttccagtgaagag
agcgactcttcatccatcagtagtcatagctctgcctcagctaatgatgtaagaaagaag
ggacatgggaagaccagaagtaaagaggtagataaattgatcagaaaccagcaaacaaat
gataggaaacaaaaagaaagaagacaagaacacgggcaccaggaaacaaggactgagaga
gaaagaaggtcagaaaaacacagagatcaaaattcaagtggttcaaattggagagatcct
ataacaaagtacacatcagacaaagatgttccttctgaacgaaataactacagtagagtt
gcgaatgacagagaccaagaaatgcatatagatttggaaaataagcatggtgatcccaaa
aagaagagaggagagagaagaaattctttttctgaaaatgagaagcatacacaccgaatt
aaagacagtgaaaatttcagaagaaaagatagatcaaagtcaaaggaaatgaatagaaag
cactcaggctcaagaagtgatgaagatagatatcaaaatggtgccgagagacgatgggaa
aaatctagcagatactctgaacaatccagagaatcaaagaaaaatcaggaccggcgaaga
gaaaagtctccagcaaaacaaaaataa

  All links  
Disease (1)   
   OMIM (1)   
Gene (23)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (31)   
   RefSeq(nuc) (5)   
   GenBank (13)   
   EMBL (13)   
3D Structure (27)   
   PDB (27)   
Protein domain (3)   
   Pfam (3)   
All databases (92)   

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