KEGG   Homo sapiens (human): 5782
Entry
5782              CDS       T01001                                 
Symbol
PTPN12, PTP-PEST, PTPG1
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 12 isoform 1
  KO
K18024  tyrosine-protein phosphatase non-receptor type 12/18/22 [EC:3.1.3.48]
Organism
hsa  Homo sapiens (human)
Disease
H00020  Colorectal cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5782 (PTPN12)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     5782 (PTPN12)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    5782 (PTPN12)
SSDB
Motif
Pfam: Y_phosphatase Tc-R-P PTP-SAK Y_phosphatase3 DSPc PTP-NADK
Other DBs
NCBI-GeneID: 5782
NCBI-ProteinID: NP_002826
OMIM: 600079
HGNC: 9645
Ensembl: ENSP00000248594.6
UniProt: Q05209
Structure
Position
7:77537295..77640069
AA seq 780 aa
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVK
KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM
IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL
EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGA
ICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQL
YEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPH
PVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNE
STIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQE
LSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHG
PENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNP
LHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTH
SGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSE
NEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT
NT seq 2343 nt   +upstreamnt  +downstreamnt
atggagcaagtggagatcctgaggaaattcatccagagggtccaggccatgaagagtcct
gaccacaatggggaggacaacttcgcccgggacttcatgcggttaagaagattgtctacc
aaatatagaacagaaaagatatatcccacagccactggagaaaaagaagaaaatgttaaa
aagaacagatacaaggacatactgccatttgatcacagccgagttaaattgacattaaag
actccttcacaagattcagactatatcaatgcaaattttataaagggcgtctatgggcca
aaagcatatgtagcaactcaaggacctttagcaaatacagtaatagatttttggaggatg
atatgggagtataatgttgtgatcattgtaatggcctgccgagaatttgagatgggaagg
aaaaaatgtgagcgctattggcctttgtatggagaagaccccataacgtttgcaccattt
aaaatttcttgtgaggatgaacaagcaagaacagactacttcatcaggacactcttactt
gaatttcaaaatgaatctcgtaggctgtatcagtttcattatgtgaactggccagaccat
gatgttccttcatcatttgattctattctggacatgataagcttaatgaggaaatatcaa
gaacatgaagatgttcctatttgtattcattgcagtgcaggctgtggaagaacaggtgcc
atttgtgccatagattatacgtggaatttactaaaagctgggaaaataccagaggaattt
aatgtatttaatttaatacaagaaatgagaacacaaaggcattctgcagtacaaacaaag
gagcaatatgaacttgttcatagagctattgcccaactgtttgaaaaacagctacaacta
tatgaaattcatggagctcagaaaattgctgatggagtgaatgaaattaacactgaaaac
atggtcagctccatagagcctgaaaaacaagattctcctcctccaaaaccaccaaggacc
cgcagttgccttgttgaaggggatgctaaagaagaaatactgcagccaccggaacctcat
ccagtgccacccatcttgacaccttctcccccttcagcttttccaacagtcactactgtg
tggcaggacaatgatagataccatccaaagccagtgttgcatatggtttcatcagaacaa
cattcagcagacctcaacagaaactatagtaaatcaacagaacttccagggaaaaatgaa
tcaacaattgaacagatagataaaaaattggaacgaaatttaagttttgagattaagaag
gtccctctccaagagggaccaaaaagttttgatgggaacacacttttgaataggggacat
gcaattaaaattaaatctgcttcaccttgtatagctgataaaatctctaagccacaggaa
ttaagttcagatctaaatgtcggtgatacttcccagaattcttgtgtggactgcagtgta
acacaatcaaacaaagtttcagttactccaccagaagaatcccagaattcagacacacct
ccaaggccagaccgcttgcctcttgatgagaaaggacatgtaacgtggtcatttcatgga
cctgaaaatgccatacccatacctgatttatctgaaggcaattcctcagatatcaactat
caaactaggaaaactgtgagtttaacaccaagtcctacaacacaagttgaaacacctgat
cttgtggatcatgataacacttcaccactcttcagaacacccctcagttttactaatcca
cttcactctgatgactcagactcagatgaaagaaactctgatggtgctgtgacccagaat
aaaactaatatttcaacagcaagtgccacagtttctgctgccactagtactgaaagcatt
tctactaggaaagtattgccaatgtccattgctagacataatatagcaggaacaacacat
tcaggtgctgaaaaagatgttgatgttagtgaagattcacctcctcccctacctgaaaga
actcctgaatcgtttgtgttagcaagtgaacataatacacctgtaagatcggaatggagt
gaacttcaaagtcaggaacgatctgaacaaaaaaagtctgaaggcttgataacctctgaa
aatgagaaatgtgatcatccagcgggaggtattcactatgaaatgtgcatagaatgtcca
cctactttcagtgacaagagagaacaaatatcagaaaatccaacagaagccacagatatt
ggttttggtaatcgatgtggaaaacccaaaggaccaagagatccaccttcagaatggaca
tga

  All links  
Disease (2)   
   OMIM (2)   
Gene (15)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (19)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (17)   
DNA sequence (45)   
   RefSeq(nuc) (19)   
   GenBank (13)   
   EMBL (13)   
3D Structure (3)   
   PDB (3)   
Protein domain (6)   
   Pfam (6)   
All databases (90)   

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