KEGG   Homo sapiens (human): 6696
Entry
6696              CDS       T01001                                 
Symbol
SPP1, BNSP, BSPI, ETA-1, OPN
Name
(RefSeq) osteopontin isoform OPN-a precursor
  KO
K06250  secreted phosphoprotein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04518  Integrin signaling
hsa04620  Toll-like receptor signaling pathway
hsa04929  GnRH secretion
hsa05165  Human papillomavirus infection
Network
nt06548  Integrin signaling
  Element
N01921  Integrin alpha4beta1 signaling
N01973  Integrin alpha4beta7 signaling
N01974  Integrin alpha9beta1 signaling
N01980  Integrin alpha5beta1 signaling
N01982  Integrin alphaVbeta1 signaling
N01983  Integrin alphaVbeta3 signaling
N01984  Integrin alphaVbeta5 signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    6696 (SPP1)
   04151 PI3K-Akt signaling pathway
    6696 (SPP1)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    6696 (SPP1)
   04518 Integrin signaling
    6696 (SPP1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    6696 (SPP1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    6696 (SPP1)
  09152 Endocrine system
   04929 GnRH secretion
    6696 (SPP1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    6696 (SPP1)
SSDB
Motif
Pfam: Osteopontin
Other DBs
NCBI-GeneID: 6696
NCBI-ProteinID: NP_001035147
OMIM: 166490
HGNC: 11255
Ensembl: ENSP00000378517.3
UniProt: P10451
Structure
Position
4:87975714..87983411
AA seq 314 aa
MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNA
VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
RISHELDSASSEVN
NT seq 945 nt   +upstreamnt  +downstreamnt
atgagaattgcagtgatttgcttttgcctcctaggcatcacctgtgccataccagttaaa
caggctgattctggaagttctgaggaaaagcagctttacaacaaatacccagatgctgtg
gccacatggctaaaccctgacccatctcagaagcagaatctcctagccccacagaatgct
gtgtcctctgaagaaaccaatgactttaaacaagagacccttccaagtaagtccaacgaa
agccatgaccacatggatgatatggatgatgaagatgatgatgaccatgtggacagccag
gactccattgactcgaacgactctgatgatgtagatgacactgatgattctcaccagtct
gatgagtctcaccattctgatgaatctgatgaactggtcactgattttcccacggacctg
ccagcaaccgaagttttcactccagttgtccccacagtagacacatatgatggccgaggt
gatagtgtggtttatggactgaggtcaaaatctaagaagtttcgcagacctgacatccag
taccctgatgctacagacgaggacatcacctcacacatggaaagcgaggagttgaatggt
gcatacaaggccatccccgttgcccaggacctgaacgcgccttctgattgggacagccgt
gggaaggacagttatgaaacgagtcagctggatgaccagagtgctgaaacccacagccac
aagcagtccagattatataagcggaaagccaatgatgagagcaatgagcattccgatgtg
attgatagtcaggaactttccaaagtcagccgtgaattccacagccatgaatttcacagc
catgaagatatgctggttgtagaccccaaaagtaaggaagaagataaacacctgaaattt
cgtatttctcatgaattagatagtgcatcttctgaggtcaattaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (18)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (73)   
   RefSeq(nuc) (5)   
   GenBank (34)   
   EMBL (34)   
3D Structure (3)   
   PDB (3)   
Protein domain (1)   
   Pfam (1)   
All databases (103)   

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