KEGG   Homo sapiens (human): 8505
Entry
8505              CDS       T01001                                 
Symbol
PARG, PARG99
Name
(RefSeq) poly(ADP-ribose) glycohydrolase isoform a
  KO
K07759  poly(ADP-ribose) glycohydrolase [EC:3.2.1.143]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03410  Base excision repair
Network
nt06504  Base excision repair
  Element
N01434  Base excision and strand cleavage by bifunctional glycosylase
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03410 Base excision repair
    8505 (PARG)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.143  poly(ADP-ribose) glycohydrolase
     8505 (PARG)
SSDB
Motif
Pfam: PARG_cat_C PARG_cat_N
Other DBs
NCBI-GeneID: 8505
NCBI-ProteinID: NP_003622
OMIM: 603501
HGNC: 8605
Ensembl: ENSP00000484285.1
UniProt: Q86W56
Structure
Position
10:complement(49818279..49942027)
AA seq 976 aa
MNAGPGCEPCTKRPRWGAATTSPAASDARSFPSRQRRVLDPKDAHVQFRVPPSSPACVPG
RAGQHRGSATSLVFKQKTITSWMDTKGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQ
HNVEKLENVSQLSLDKSPTEKSTQYLNQHQTAAMCKWQNEGKHTEQLLESEPQTVTLVPE
QFSNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKS
CDPGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEP
ESPMDVDNSKNSCQDSEADEETSPGFDEQEDGSSSQTANKPSRFQARDADIEFRKRYSTK
GGEVRLHFQFEGGESRTGMNDLNAKLPGNISSLNVECRNSKQHGKKDSKITDHFMRLPKA
EDRRKEQWETKHQRTERKIPKYVPPHLSPDKKWLGTPIEEMRRMPRCGIRLPLLRPSANH
TVTIRVDLLRAGEVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQ
TALLNKFTRPQNLKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKI
ALCLPNICTQPIPLLKQKMNHSITMSQEQIASLLANAFFCTFPRRNAKMKSEYSSYPDIN
FNRLFEGRSSRKPEKLKTLFCYFRRVTEKKPTGLVTFTRQSLEDFPEWERCEKPLTRLHV
TYEGTIEENGQGMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIISRLFTEVLDHNEC
LIITGTEQYSEYTGYAETYRWSRSHEDGSERDDWQRRCTEIVAIDALHFRRYLDQFVPEK
MRRELNKAYCGFLRPGVSSENLSAVATGNWGCGAFGGDARLKALIQILAAAAAERDVVYF
TFGDSELMRDIYSMHIFLTERKLTVGDVYKLLLRYYNEECRNCSTPGPDIKLYPFIYHAV
ESCAETADHSGQRTGT
NT seq 2931 nt   +upstreamnt  +downstreamnt
atgaatgcgggccccggctgtgaaccctgcaccaagcgaccccgctggggcgccgctaca
acttcgccggctgcttcggacgcccggagctttcccagcaggcagaggcgcgtcctcgac
cccaaggacgctcacgtgcagttcagggtcccaccgtcctcgccagcctgcgtcccaggg
cgggcgggacagcacagaggcagcgccacctcgcttgttttcaaacaaaagactattacc
agttggatggacactaaaggaatcaagacagcggaatcagaaagtttggatagtaaagaa
aacaacaatacaagaatagaatccatgatgagttctgtacaaaaagataacttttaccaa
cataatgtagaaaaattagaaaatgtttctcagctaagtcttgataagtcacccactgaa
aaaagtacacagtatttgaaccagcatcagactgcagcaatgtgtaagtggcaaaatgaa
gggaaacacacggagcagcttttggaaagtgaacctcaaacagtaaccctggtaccagag
cagtttagtaatgctaacattgatcggtcacctcaaaatgatgatcacagtgacacagat
agtgaagagaatagagacaatcaacagtttctcacaactgtaaagcttgcaaatgcaaag
cagactacagaagatgaacaggccagagaagccaaaagccaccagaagtgcagcaagtct
tgcgatcctggggaagactgtgcaagttgtcagcaagatgagatagatgtggtgccagag
agtccattgtcagatgttggctctgaggatgttggtactgggccaaaaaatgacaacaaa
ttgactagacaagaaagttgcctaggaaattctcctccatttgagaaggaaagtgaaccc
gagtcaccgatggatgtggataattctaaaaatagttgtcaagactcagaagcagatgag
gagacaagtccaggttttgatgaacaagaagatggtagttcctcccaaacagcaaataaa
ccttcaaggttccaagcaagagacgctgacattgaatttaggaaacggtactctactaag
ggcggtgaagttagattacatttccaatttgaaggaggagagagtcgcactggaatgaat
gatttaaatgctaaactacctggaaatatttctagcctgaatgtagaatgcagaaattct
aagcaacatggaaaaaaggattctaaaatcacagatcatttcatgagactgcccaaagca
gaggacagaagaaaagaacagtgggaaaccaaacatcaaagaacagaaaggaagatccct
aaatacgttccacctcacctttctccagataagaagtggcttggaactcccattgaggag
atgagaagaatgcctcggtgtgggatccggctgcctctcttgagaccatctgccaatcac
acagtaactattcgggtagatcttttgcgagcaggagaagttcctaaaccttttccaaca
cattataaagatttgtgggataacaagcatgttaaaatgccttgttcagaacaaaatttg
tacccagtggaagatgagaatggtgagcgaactgcggggagccggtgggagctcattcag
actgcacttctcaacaaatttacacgaccccaaaacttgaaggatgctattctgaaatac
aatgtggcatattctaagaaatgggactttacagctttgatcgatttctgggataaggta
cttgaagaagcagaagctcaacatttatatcagtccatcttgcctgatatggtgaaaatt
gcactctgtctgccaaatatttgcacccagccaataccactcctgaaacagaagatgaat
cattccatcacaatgtcgcaggaacagattgccagtcttttagctaatgctttcttctgc
acatttccacgacgaaatgctaagatgaaatcggagtattctagttacccagacattaac
ttcaatcgattgtttgagggacgttcatcaaggaaaccggagaaacttaaaacgctcttc
tgctactttagaagagtcacagagaaaaaacctactgggttggtgacatttacaagacag
agtcttgaagattttccagaatgggaaagatgtgaaaaacccttgacacgattgcatgtc
acttacgaaggtaccatagaagaaaatggccaaggcatgctacaggtggattttgcaaat
cgttttgttggaggtggtgtaaccagtgcaggacttgtgcaagaagaaatccgcttttta
atcaatcctgagttgattatttcacggctcttcactgaggtgctggatcacaatgaatgt
ctaattatcacaggtactgagcagtacagtgaatacacaggctatgctgagacatatcgt
tggtcccggagccacgaagatgggagtgaaagggacgactggcagcggcgctgcactgag
atcgttgccatcgatgctcttcacttcagacgctacctcgatcagtttgtgcctgagaaa
atgagacgcgagctgaacaaggcttactgtggatttctccgtcctggagtttcttcagag
aatctttctgcagtggccacaggaaactggggctgtggtgcctttgggggtgatgccagg
ttaaaagccttaatacagatattggcagctgctgcagctgagcgagatgtggtttatttc
acctttggggactcagaattgatgagagacatttacagcatgcacattttccttactgaa
aggaaactcactgttggagatgtgtataagctgttgctacgatactacaatgaagaatgc
agaaactgttccacccctggaccagacatcaagctttatccattcatataccatgctgtc
gagtcctgtgcagagaccgctgaccattcagggcaaaggacagggacctga

  All links  
Disease (1)   
   OMIM (1)   
Gene (31)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (13)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (57)   
   RefSeq(nuc) (17)   
   GenBank (20)   
   EMBL (20)   
3D Structure (25)   
   PDB (25)   
Protein domain (2)   
   Pfam (2)   
All databases (126)   

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