Entry |
|
Name |
|
Gene |
|
Organism |
hsa_var Human gene variants (Homo sapiens)
|
Variation |
|
Network |
|
Element |
N01135 | Mutation-caused aberrant SOD1 to intrinsic apoptotic pathway |
N01144 | Mutation-caused aberrant SOD1 to 26S proteasome-mediated protein degradation |
N01147 | Mutation-caused aberrant SOD1 to ATF6-mediated transcription |
N01148 | Mutation-caused aberrant SOD1 to IRE1a-XBP1 signaling pathway |
N01149 | Mutation-caused aberrant SOD1 to PERK-ATF4 signaling pathway |
N01160 | Mutation-caused aberrant SOD1 to retrograde axonal transport |
|
Disease |
H00058 | Amyotrophic lateral sclerosis (ALS) |
|
Reference |
|
Authors |
Nguyen HP, Van Broeckhoven C, van der Zee J |
Title |
ALS Genes in the Genomic Era and their Implications for FTD. |
Journal |
|
Reference |
|
Authors |
Khalil B, Lievens JC |
Title |
Mitochondrial quality control in amyotrophic lateral sclerosis: towards a common pathway? |
Journal |
|