KEGG   PATHWAY: ko00740
ko00740                     Pathway                                

Riboflavin metabolism
Metabolism; Metabolism of cofactors and vitamins
Pathway map
ko00740  Riboflavin metabolism

M00125  Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:ko00740]
M00911  Riboflavin biosynthesis, fungi, GTP => riboflavin/FMN/FAD [PATH:ko00740]
Other DBs
GO: 0006771
K01497  GTP cyclohydrolase II [EC:]
K14652  3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:]
K08096  GTP cyclohydrolase IIa [EC:]
K14653  2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase [EC:]
K01498  diaminohydroxyphosphoribosylaminopyrimidine deaminase [EC:]
K00082  5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:]
K11752  diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:]
K14654  2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:]
K14655  tRNA pseudouridine32 synthase / 2,5-diamino-6-(5-phospho-D-ribitylamino)-pyrimidin-4(3H)-one deaminase [EC:]
K22912  5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:]
K20860  FMN hydrolase / 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:]
K20861  FMN hydrolase / 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:]
K20862  FMN hydrolase / 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:]
K21063  5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:]
K21064  5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:]
K02858  3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:]
K00794  6,7-dimethyl-8-ribityllumazine synthase [EC:]
K00793  riboflavin synthase [EC:]
K00861  riboflavin kinase [EC:]
K20884  riboflavin kinase / FMN hydrolase [EC:]
K11753  riboflavin kinase / FMN adenylyltransferase [EC:]
K07732  riboflavin kinase, archaea type [EC:]
K01078  acid phosphatase [EC:]
K23458  repressible acid phosphatase [EC:]
K01093  4-phytase / acid phosphatase [EC:]
K03788  acid phosphatase (class B) [EC:]
K09474  acid phosphatase (class A) [EC:]
K14379  tartrate-resistant acid phosphatase type 5 [EC:]
K14394  low molecular weight phosphotyrosine protein phosphatase [EC:]
K14410  lysosomal acid phosphatase [EC:]
K00953  FAD synthetase [EC:]
K22949  FAD synthetase [EC:]
K14656  FAD synthetase [EC:]
K01513  ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:]
K18453  ADP-ribose/FAD diphosphatase [EC:]
K05901  biliverdin reductase / flavin reductase [EC:]
K00484  flavin reductase (NADH) [EC:]
K22393  flavin reductase (NADH) subunit 1 [EC:]
K22394  flavin reductase (NADH) subunit 2 [EC:]
K23470  4-hydroxyphenylacetate 3-hydroxylase, reductase component [EC:]
K05368  NAD(P)H-flavin reductase [EC:]
K23462  flavin-dependent trigonelline monooxygenase, reductase component [EC:]
K00299  FMN reductase [EC:]
K19285  FMN reductase (NADPH) [EC:]
K19286  FMN reductase [NAD(P)H] [EC:]
K20146  nitrilotriacetate monooxygenase reductase component [EC:]
K04719  5,6-dimethylbenzimidazole synthase [EC:]
K15245  flavin reductase [EC:]
K16902  FAD reductase [NAD(P)H] [EC:]
K00878  hydroxyethylthiazole kinase [EC:]
K01515  ADP-ribose pyrophosphatase [EC: 3.6.1.-]
K12152  phosphatase NudJ [EC:3.6.1.-]
K25520  IPP/DMAPP-specific nudix hydrolase [EC:3.6.1.-]
K03186  flavin prenyltransferase [EC:]
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
Nucleic Acids Res 30:3141-51 (2002)
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
Eur J Biochem 269:519-26 (2002)
Haase I, Fischer M, Bacher A, Schramek N.
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
J Biol Chem 278:37909-15 (2003)
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
Biochem Soc Trans 33:780-4 (2005)
ko00030  Pentose phosphate pathway
ko00040  Pentose and glucuronate interconversions
ko00230  Purine metabolism
ko00860  Porphyrin metabolism
ko00900  Terpenoid backbone biosynthesis

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