KEGG   Latimeria chalumnae (coelacanth): 102345855
Entry
102345855         CDS       T02913                                 
Symbol
PLCB1
Name
(RefSeq) phospholipase C beta 1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
lcm  Latimeria chalumnae (coelacanth)
Pathway
lcm00562  Inositol phosphate metabolism
lcm01100  Metabolic pathways
lcm04020  Calcium signaling pathway
lcm04070  Phosphatidylinositol signaling system
lcm04081  Hormone signaling
lcm04082  Neuroactive ligand signaling
lcm04261  Adrenergic signaling in cardiomyocytes
lcm04270  Vascular smooth muscle contraction
lcm04310  Wnt signaling pathway
lcm04371  Apelin signaling pathway
lcm04540  Gap junction
lcm04621  NOD-like receptor signaling pathway
lcm04912  GnRH signaling pathway
lcm04916  Melanogenesis
Module
lcm_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:lcm00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102345855 (PLCB1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    102345855 (PLCB1)
   04371 Apelin signaling pathway
    102345855 (PLCB1)
   04020 Calcium signaling pathway
    102345855 (PLCB1)
   04070 Phosphatidylinositol signaling system
    102345855 (PLCB1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    102345855 (PLCB1)
   04081 Hormone signaling
    102345855 (PLCB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    102345855 (PLCB1)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    102345855 (PLCB1)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102345855 (PLCB1)
   04916 Melanogenesis
    102345855 (PLCB1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102345855 (PLCB1)
   04270 Vascular smooth muscle contraction
    102345855 (PLCB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lcm04131]
    102345855 (PLCB1)
Enzymes [BR:lcm01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     102345855 (PLCB1)
Membrane trafficking [BR:lcm04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    102345855 (PLCB1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    102345855 (PLCB1)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PI-PLC-Y PLCB1-4-like_EFh PH_14 EF-hand_like DUF6158
Other DBs
NCBI-GeneID: 102345855
NCBI-ProteinID: XP_014346243
Ensembl: ENSLACG00000010310
Position
Un
AA seq 1088 aa
METDLLDISHIKDSRNGKCTRTPKDPRLRELLDVGNLGGRLENRMLTVVYGPDLANITYL
NFMAFQEEVAKEWADELFGLATNLLAQNMSRDAFLEKVYTKLKLQLNPEGRIPVKNIYRL
FSADRKRVETALESCSLPSGRNDIIPQEDFTPEMYRMFLNSICPRPEIDNIFSEYGAKSK
PYLTVDQMIEFINSKQRDPRLNEILYPPLKQEQVQQLIEKYEPNISLAKKGQISVDGFMH
YLSGEENGVVPPEKLDQSEDMSQPLSHYFINSSHNTYLIAGQLAGTSSVEMYRQVLLLGC
RCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPVILSFENHVDS
LKQQAKMAEHCKTIFGDMLLTDPLEKYPLDSGVPLPSPMDLMFKILIKNKKKSHKSLDGS
AKKKLSEQASNTYSDTSSVFEPSSPGAGSTNPEIPDVQQIVTDGNDQKPVRRKSIGETEV
ESDEEEEDDDDSKKSSMDEGTAGSEACATEEMSNLVNYIQPVKFESFESAKKHNKSFEMS
SFVETKGLEQLTKSPVEFVEYNKKQLSRIYPKGTRVDSSNYMPQVFWNAGCQLVALNFQT
LDLPMQLNMGMFEYNGKSGFRLKPEFMRRPDKHFDPFTETTVDGIVANTVSVKIISGQFL
SDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEDPIVFKKVVLPSLASLRIS
VYEEGGKFIGHRILPVSAIRPGYHYICLRNERNQPLMLPALFVYIEVKDYVPDTFADVIE
ALSNPIRYVNLMEQRARQLVALTLEDEEEVKKEIDPGEVAPESSNDTRLLPAENGMNHTP
SITPKAPSQVVHSQPATGSVKAPAKTEDLIQSVLIEVEPQTIEELRQQKAFVKLQKKHYK
EMKELVKKHHKKTTDLIKEHTAKYNEFQNEYLRRRSVLEKSAKRDGKKRCESGSPDHTTS
TIEQDLSVLDTEMAQRLAELKEQQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTEVAEE
CQNSQLKKLKELSEKEKKELKKKMDKKRQEKITEAKSKDKNQMEEEKTEIIRTYIQEVVQ
YIKRVCKQ
NT seq 3267 nt   +upstreamnt  +downstreamnt
atggaaacagaccttctagatatcagccacatcaaggacagcagaaatgggaaatgtacc
agaactccaaaggatcccagactacgggaactgcttgatgtgggaaatcttggaggtcgg
cttgagaacaggatgcttactgtggtgtatggtcctgacttggctaatattacctatcta
aacttcatggccttccaggaggaagtcgcaaaggaatgggcagatgagctgttcggtctg
gcaacaaacctgctggcacaaaacatgtctagggatgcgtttctggaaaaagtatataca
aaacttaagttgcagctaaatccagaaggccgcattcctgtaaagaacatatatcgctta
ttttcagctgatcggaagcgagtagaaacagcattagaatcctgtagtcttccatctggc
cgtaatgacatcattcctcaagaagacttcactcctgaaatgtacagaatgtttttaaat
agtatctgtcctcgtcctgaaatagataacatattttcagaatatggagcaaagagtaaa
ccgtaccttacagttgatcagatgatagagtttattaactccaaacagcgggacccacgg
ttaaatgaaattctgtatccacctttaaaacaggaacaagttcaacaactcatcgagaaa
tatgaaccaaatatcagtcttgcaaagaaaggacagatatcagtggatgggttcatgcac
tacctgagcggagaggagaatggagttgtcccacctgagaaactggatcaaagtgaagac
atgtctcaacctttatctcactactttatcaattcctcacacaacacctacctcatagct
gggcagcttgcaggtacctcttcagtagagatgtaccggcaagtgctgttgttaggctgt
cgctgtgtggagctggactgttggaaaggacgaactgcagaagaagagccagtcattaca
catggattcacaatgacaactgaaatatccttcaaggaagttatagaagccattgcagag
tgtgctttcaagacatctccatttccagtcatcctttcctttgaaaaccatgtagattca
cttaaacagcaagccaagatggcagagcattgcaaaacaatatttggagatatgctgctt
actgatccactagaaaagtacccacttgattctggtgtcccgcttccaagtcccatggac
ctaatgtttaaaattttgataaaaaataagaagaaatcccacaagtcattagatggaagt
gcaaaaaagaagctttcagaacaagcttcaaatacttacagtgacacatccagtgtattt
gagccctcatctccaggagcaggttcaacaaaccctgagataccagatgtccagcagatt
gtcacagatgggaatgaccagaagcctgttcgtagaaaatctataggagagacagaagta
gagagtgatgaagaggaggaggatgatgatgactctaaaaaatcttccatggatgagggg
actgctgggagtgaagcctgtgccactgaagagatgtctaacctggtgaattatattcag
ccagtaaagtttgagtcatttgagtcagcaaaaaaacacaacaagagttttgaaatgtct
tcattcgtggaaacaaagggtttagaacaactcacgaagtctccagtggagtttgtggaa
tataacaaaaagcagctcagcaggatctatccaaaaggaacacgagtggattcttcaaac
tacatgccccaggtcttctggaatgctggttgtcagttggttgctttgaacttccaaaca
ttagatttacctatgcagttaaatatggggatgtttgaatacaatggcaaaagtggattt
cggctgaagccagagttcatgagaagaccagacaagcattttgaccctttcacagaaacc
acagtggatggaatagtggctaatactgtatcagttaagataatttcaggtcagtttctg
tctgataaaaaagttggtacatatgtagaagtggacatgtttggtctacctgtggacaca
agaaggaaagctttcaaaacaaagacatctcaaggaaatgctgtgaaccctgtctgggaa
gaagacccaatagtattcaaaaaggttgtcttgccctctttggcttctttaagaatatca
gtgtatgaagaaggaggtaaatttattggtcacaggatattgccagtctcagcaattcgg
ccaggttaccactacatttgtttaagaaatgaaaggaaccagcctctgatgctaccagct
ctctttgtgtacattgaggttaaagattatgttccagacacctttgcagatgtgattgaa
gccttgtctaatcctataaggtatgtcaatcttatggaacaaagagcaaggcaattagtt
gcactaactctagaggatgaagaagaagtaaagaaagagattgacccaggggaggtggct
ccagagtctagtaatgataccaggctactgcccgcagaaaatggaatgaaccataccccc
tccataactcctaaagctccaagtcaggttgtccacagtcagccagcaacaggctcagtt
aaagcacctgctaaaacagaagatcttatccagagtgtcttgatagaggtggaaccacag
actattgaagaactgagacaacaaaaggcatttgtgaagcttcagaagaagcactacaaa
gaaatgaaggagcttgttaagaaacatcacaagaagactacagatctgatcaaagaacat
actgctaaatacaatgagtttcagaatgagtatttacgacgcagatctgtcctagaaaaa
tcggctaaaagagatggtaagaaaaggtgtgaatcaggtagcccagaccacactacttca
actattgaacaagatctctctgtactggacacagagatggcccagagattagctgagctg
aaagaacagcaacagcaacagctgctaaacctcagacaagaacagtattatagtgagaag
tatcagaagcgagaacatattaagctgctaattcaaaaactgacagaggtggcagaagag
tgccagaatagccagttaaagaagctaaaagaactttctgaaaaagaaaagaaagaattg
aaaaagaaaatggacaaaaagagacaggaaaagatcacagaagcaaaatccaaggacaaa
aaccaaatggaagaagagaagacagaaattatccgaacctacatacaggaagtggtgcag
tatatcaagcgagtatgtaaacaataa

  All links  
Gene (17)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (26)   

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