KEGG   Leucoraja erinaceus (little skate): 129699284
Entry
129699284         CDS       T09122                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
leri  Leucoraja erinaceus (little skate)
Pathway
leri00562  Inositol phosphate metabolism
leri01100  Metabolic pathways
leri04020  Calcium signaling pathway
leri04070  Phosphatidylinositol signaling system
leri04081  Hormone signaling
leri04082  Neuroactive ligand signaling
leri04261  Adrenergic signaling in cardiomyocytes
leri04270  Vascular smooth muscle contraction
leri04310  Wnt signaling pathway
leri04371  Apelin signaling pathway
leri04540  Gap junction
leri04621  NOD-like receptor signaling pathway
leri04912  GnRH signaling pathway
leri04916  Melanogenesis
Module
leri_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:leri00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    129699284
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    129699284
   04371 Apelin signaling pathway
    129699284
   04020 Calcium signaling pathway
    129699284
   04070 Phosphatidylinositol signaling system
    129699284
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    129699284
   04081 Hormone signaling
    129699284
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    129699284
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    129699284
  09152 Endocrine system
   04912 GnRH signaling pathway
    129699284
   04916 Melanogenesis
    129699284
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    129699284
   04270 Vascular smooth muscle contraction
    129699284
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:leri04131]
    129699284
Enzymes [BR:leri01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     129699284
Membrane trafficking [BR:leri04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    129699284
 Endocytosis
  Macropinocytosis
   Phospholipase C
    129699284
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like PLC-beta_C C2 EF-hand_7 EF-hand_6 Thioredoxin_17
Other DBs
NCBI-GeneID: 129699284
NCBI-ProteinID: XP_055494916
Position
8:complement(7065920..7590408)
AA seq 1213 aa
MAKAYEFMWQKRVPSFMQEGAVFDRYEEEPSVFEPNCLVKVDEFGFFLTWKSDGKEGQVL
ECSMVNSIRYGNIRKDPKLLSALEAVGKAENELDGRIFCICCDADLVNISFTYLVAESAD
TAKHWVEGLKSIVHNFKANSVCPMTCLTKHWMRLSFLTNVNGKIPVRSITRTFASGKTEK
VIFQVLKELGFPSGKIDEIEPAVFTFDKFYALTQKICPRTDIEELFRKLNGDKTDYLTVD
QLVSFLNENQRDPRLNEILFPFYDTKRAMQILEHYEPDEALRKQARMSSDGFCRYLMSDE
NAPVFLDRLELYQEMDQPLSHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLSGCRCIELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSQYPVILSFENHCSKPQQYKM
AKYSEEIFGDLLLKQPLENNPLDAGRPLASPNDLKRKILIKNKRLKPEVESKQLETFKSL
MEGGEATSPASMLEDENEEEIENADLSSISVDQDEAHPELKINSELSADDITQEKEALVN
SVKKVIEDTEPESNKKGTITVEDEQAWVSSYTYVGATTNIHPYLSAMVNYAQPVKFQGFK
IAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWN
AGCQMVSLNFQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAA
TCSVKVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEEPFVFRK
VILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGCRHISLRNEGNKPLSLPTVFCNIVLK
TYVPDGFGDIVDALSDPKKFLSVMEKRADQMRAMGIETSDIADVPSDNTKNDKRGKANTA
KASVTPQSSSELRQNSTAGQGVGNDAKKDMTLVPQVNIEDLKQMKAYLKLQKKQQKELSA
TKKKHGKDHCATQKSHCMQVDKLVAQHDKEKLTQEKILEKAIKKKGENNCVDLKKETEIK
IETLSSDHKLKVKEIVTQQTKEWSEMLNVHCAEEQEQRDLHLSQQCDLLKKLLMNMHEQQ
SQHLKLIHDRHSKEMRANQAKSSMENSKAISHDKRIKNKAERERRVRELNSSNTKKFLEE
RKRLAMKQSKEMDQLRKAQLEQLEGLERQNDQLLKSCHAGCVFQGKRDAEDGEAGGRNGS
STSDSGLNSPEAD
NT seq 3642 nt   +upstreamnt  +downstreamnt
atggcgaaagcgtatgagttcatgtggcaaaaaagggttccttcctttatgcaagagggt
gccgtcttcgacagatatgaagaggaaccgtctgtgttcgaaccaaactgtcttgtgaaa
gtggatgaatttggattcttcctcacctggaaaagtgatggaaaggaaggacaagtgctg
gaatgttccatggtcaacagcattcgatatgggaatatccgcaaggatcccaaattactg
tctgcgctggaggcagtgggaaaagcggaaaacgagctggacggaaggatattttgcatt
tgttgcgatgcagacctggtgaacatcagctttacgtatctggtggctgagagtgctgac
acggccaagcattgggttgagggattgaaatcgattgtccacaacttcaaagcgaacagt
gtctgccctatgacctgtctcacaaaacactggatgagattatcgtttctgactaatgta
aatggaaagattccagtaaggagtattaccagaacttttgcatcaggcaagacagaaaag
gtgatatttcaggtattgaaagaactcggttttccaagtggcaagattgatgagattgag
ccagctgttttcacctttgataagttttatgcactaactcaaaaaatttgcccgcgcact
gacatcgaagaactattcaggaaactcaatggagacaaaactgattacttaactgtagac
caattagtcagctttctgaatgaaaatcaacgagatcctcgtctgaacgagattctgttt
cccttctatgataccaaaagagcaatgcagatcctcgagcactatgaacccgatgaagcg
ttgaggaagcaagccaggatgtcgtccgatgggttctgcaggtacctgatgtcggatgaa
aatgcaccagtcttcctcgaccgcttggagctgtatcaagaaatggaccaacccctctcg
cactatttcatcagctcctcacacaacacctatctcacgggtcggcagtttggaggcaag
tcttcagtggagatgtacagacaagtccttctgtctggctgcagatgtattgaattagat
tgctgggatgggaaaggggaggaccaagagccaataataacacacggcaaggcgatgtgc
acagatattctttttaaggatgtaatacaagccatcaaggagacggcatttgtaacatca
caataccccgttatcctctcatttgaaaatcactgcagcaaaccccagcagtacaagatg
gccaagtacagtgaagaaatctttggagaccttctcttgaagcagccgctggaaaacaac
ccactagatgccggcagacccctggcatctccgaacgacctgaagagaaaaatactcatc
aaaaataagaggttaaaacctgaagtagagtcaaagcagcttgagacgtttaaaagcctg
atggagggcggggaagccaccagcccagccagcatgttggaggatgaaaacgaggaggaa
atcgaaaacgctgacctatcatcgatttcggttgaccaagatgaagcacatcctgaattg
aaaatcaatagtgagctttctgcagatgacataactcaggagaaagaagcacttgttaat
agtgtgaagaaggtaatcgaagacactgaaccggagagtaacaaaaagggaactataact
gtagaagatgaacaggcctgggtatcatcctatacttatgttggagccaccaccaatata
catccctacttgtccgccatggtcaactatgcccagccagtgaaatttcaaggctttaag
attgcagaagagcgaaatatccactacaatatgtcctcgtttaatgagtcggttggactg
ggatatctgaagacacacgcgatagagttcgtcaattataataagcgacaaatgagccgc
atttaccccaagggtggtcgcgtggattccagcaattacatgcctcagatcttctggaac
gctggctgccagatggtctccctgaacttccagactccagatttagccatgcagttaaat
cagggaaagtttgaatacaatggatcgtgtggttatctcctgaagcctgatttcatgcgg
cgaccagaccggacctttgacccgttctccgagaccccggtggacggtgtgattgcagct
acctgctctgtaaaggtgatatcgggacagtttctatcagataagaaaatcggcacgtat
gtagaggtggacatgtacggtctccccactgatacaatacgcaaggagttccgtacgcgg
atggtgatgaacaacggtttgaacccagtgtacaatgaggagccatttgtattcaggaag
gtaattctgcctgacctggcggtattgaggatagcagtgtacgatgacaacaacaagttg
attggccagcggatcttgcctttggatgggcttcaagctggctgcaggcacatctcgctc
cgaaatgaaggcaacaagcccctgtctctgcccacagtcttctgtaacattgtgctgaaa
acatacgttccggatggctttggagatatcgttgatgctctgtcagatccgaagaaattt
ttgtctgtgatggagaagcgggctgaccaaatgcgggcaatgggaattgaaactagcgat
atcgcggatgtgccgagcgacaacaccaaaaacgacaagagagggaaggccaatacggcg
aaagcaagtgtcacgccacagagcagctcggaactgcggcaaaattcaacggccgggcaa
ggagtcggaaacgatgcaaagaaagatatgacactcgtacctcaggtgaatattgaggac
ttgaagcagatgaaggcctatctaaagttgcagaagaagcaacaaaaagaactgagtgca
acaaagaaaaagcatggcaaggatcactgtgccacacagaagtcacattgtatgcaggtg
gacaaacttgtagcccagcatgacaaggagaaattaacccaagagaagatcttggagaag
gcaatcaagaaaaagggagaaaacaattgcgttgatttgaagaaggaaaccgagatcaaa
atagaaaccttatcttcagatcacaaattaaaggtgaaagagatagtcacccagcagacc
aaggagtggtcggagatgttaaatgttcattgtgcagaggaacaggagcaaagggacctt
cacttgagccaacaatgtgatttgttaaagaaactcctcatgaacatgcacgagcagcaa
agccagcatctcaaactcatccatgatcggcacagcaaagaaatgcgagctaatcaagcc
aagagttccatggagaacagcaaagccataagccacgataaaagaatcaaaaataaagct
gaaagggaaaggcgggtgagagagctgaacagcagcaacactaaaaagttcctggaagaa
cggaaacggctcgcaatgaagcaatccaaggaaatggaccaattaaggaaagctcagctc
gaacaactggagggcttggaaagacaaaatgatcagctgctgaaatcatgtcatgcaggg
tgtgtcttccaaggcaaaagagatgcggaagatggtgaagctggaggcagaaatggctcg
tcgaccagcgacagtggtctgaattccccagaagccgactga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (7)   
   RefSeq(pep) (7)   
DNA sequence (7)   
   RefSeq(nuc) (7)   
Protein domain (10)   
   Pfam (10)   
All databases (26)   

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