KEGG   Leopardus geoffroyi (Geoffroy's cat): 123603733
Entry
123603733         CDS       T10761                                 
Symbol
STAT3
Name
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
lgf  Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf01521  EGFR tyrosine kinase inhibitor resistance
lgf04062  Chemokine signaling pathway
lgf04066  HIF-1 signaling pathway
lgf04068  FoxO signaling pathway
lgf04081  Hormone signaling
lgf04217  Necroptosis
lgf04550  Signaling pathways regulating pluripotency of stem cells
lgf04630  JAK-STAT signaling pathway
lgf04659  Th17 cell differentiation
lgf04917  Prolactin signaling pathway
lgf04920  Adipocytokine signaling pathway
lgf04931  Insulin resistance
lgf04933  AGE-RAGE signaling pathway in diabetic complications
lgf04935  Growth hormone synthesis, secretion and action
lgf05145  Toxoplasmosis
lgf05160  Hepatitis C
lgf05161  Hepatitis B
lgf05162  Measles
lgf05163  Human cytomegalovirus infection
lgf05167  Kaposi sarcoma-associated herpesvirus infection
lgf05169  Epstein-Barr virus infection
lgf05171  Coronavirus disease - COVID-19
lgf05200  Pathways in cancer
lgf05203  Viral carcinogenesis
lgf05205  Proteoglycans in cancer
lgf05206  MicroRNAs in cancer
lgf05207  Chemical carcinogenesis - receptor activation
lgf05212  Pancreatic cancer
lgf05221  Acute myeloid leukemia
lgf05223  Non-small cell lung cancer
lgf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
lgf05321  Inflammatory bowel disease
lgf05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lgf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    123603733 (STAT3)
   04066 HIF-1 signaling pathway
    123603733 (STAT3)
   04068 FoxO signaling pathway
    123603733 (STAT3)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    123603733 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    123603733 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    123603733 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    123603733 (STAT3)
   04062 Chemokine signaling pathway
    123603733 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    123603733 (STAT3)
   04917 Prolactin signaling pathway
    123603733 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    123603733 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123603733 (STAT3)
   05206 MicroRNAs in cancer
    123603733 (STAT3)
   05205 Proteoglycans in cancer
    123603733 (STAT3)
   05207 Chemical carcinogenesis - receptor activation
    123603733 (STAT3)
   05203 Viral carcinogenesis
    123603733 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123603733 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    123603733 (STAT3)
   05221 Acute myeloid leukemia
    123603733 (STAT3)
   05223 Non-small cell lung cancer
    123603733 (STAT3)
  09172 Infectious disease: viral
   05161 Hepatitis B
    123603733 (STAT3)
   05160 Hepatitis C
    123603733 (STAT3)
   05171 Coronavirus disease - COVID-19
    123603733 (STAT3)
   05162 Measles
    123603733 (STAT3)
   05163 Human cytomegalovirus infection
    123603733 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123603733 (STAT3)
   05169 Epstein-Barr virus infection
    123603733 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123603733 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    123603733 (STAT3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123603733 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    123603733 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123603733 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123603733 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:lgf03000]
    123603733 (STAT3)
Transcription factors [BR:lgf03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    123603733 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int STAT_linker SH2 E2R135 Baculo_PEP_C
Other DBs
NCBI-GeneID: 123603733
NCBI-ProteinID: XP_045344877
Position
E1:complement(40878333..40947131)
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagctacagcagctcgacacacggtacctggagcagcttcatcag
ctgtacagtgacagcttcccaatggagctgcggcagtttctggccccttggattgagagt
caagattgggcatatgcggccagcaaagaatcacatgctactttggtgtttcataatctc
ttgggtgagattgaccagcagtacagccgtttcctacaggaatcgaatgttctctatcag
cacaatctgcgaagaatcaagcagttccttcagagcaggtatctggagaagccaatggag
attgcccgaattgtggcccggtgcctgtgggaagagtcccgcctgctccagactgcagcc
actgcagcccagcaagggggccaggccaaccaccccacggccgccgtggtgacggagaag
cagcagatgctggagcagcacctgcaagatgttcggaagcgagtacaggacctagaacag
aaaatgaaagtggtagagaacctccaggatgactttgacttcaactataaaaccctcaag
agtcaaggagacatgcaggatctgaatggaaacaaccagtccgtgaccaggcagaagatg
cagcagctggaacagatgctcacggcgctggaccagatgcggcgcagcatcgtgagtgag
ttggcggggctgttgtcagccatggagtatgtgcagaagacgctcacggatgaagagctg
gctgactggaagaggcggcagcagattgcgtgcatcgggggcccgcccaacatctgcctc
gaccgcctagaaaactggataacctcgttagcggaatctcaacttcagacccgccaacaa
attaagaaactggaggagttgcagcaaaaagtgtcctacaaaggggatcccattgtacag
caccggccaatgctggaggagaggattgtggagctgtttagaaacttaatgaaaagtgcc
tttgtggttgagcggcagccctgcatgcccatgcatcccgaccggccattggtcatcaag
actggcgtccagttcactaccaaagtcagattgctggtcaaattccctgagttaaattat
cagcttaaaattaaagtgtgcattgacaaagactccggggatgttgcagcgctcagagga
tcccggaaatttaacattctgggcacaaacacgaaagtgatgaacatggaagagtccaac
aacggcagcctctctgcagaattcaaacatctgaccctgagagagcaaagatgtggtaac
gggggccgagccaattgtgacgcctccctgattgtcaccgaggagctgcacctgatcacc
tttgagactgaggtgtatcaccagggcctcaagattgaccttgagacccactccttgccg
gttgtggtgatctccaacatctgtcagatgcctaatgcctgggcatctatcctgtggtat
aacatgctgaccaacaaccccaagaacgtgaactttttcaccaagcccccgattggaacc
tgggatcaagtggctgaggtgctgagctggcagttctcctccaccacaaagcgaggcctg
agcattgagcagttgacgacgctggcagagaagctcttaggacctggtgtgaactattca
gggtgtcagattacgtgggctaaattttgcaaagaaaacatggccggcaaaggcttctcc
ttctgggtctggctagacaatatcattgatcttgtgaaaaagtacatcctggctctttgg
aatgaagggtacataatgggttttatcagtaaggagcgggagcgggccatcttgagcacc
aagcccccaggcaccttcctgctaagattcagtgaaagcagcaaagaaggaggtgtcacc
ttcacttgggtggagaaggacatcagcggcaagacccagatccagtccgtggaaccatat
accaagcagcagctgaacaacatgtcgtttgctgaaatcatcatgggctataagatcatg
gatgctaccaacatcctcgtgtctccgctggtttatctctacccggacattcctaaggag
gaggcgtttggaaagtattgtcgaccagaaagccaggagcatcctgaagctgacccaggt
agtgctgccccatacctgaagaccaagtttatctgtgtgacaccaacgacctgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataat
ggtgaaggtgctgaaccctcagcaggagggcagtttgaatccctcacgttcgacatggag
ttgacctcggagtgcgccacctccccaatgtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (7)   
   Pfam (7)   
All databases (19)   

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