KEGG   Leopardus geoffroyi (Geoffroy's cat): 123606170
Entry
123606170         CDS       T10761                                 
Symbol
ADCY1
Name
(RefSeq) adenylate cyclase type 1 isoform X1
  KO
K08041  adenylate cyclase 1 [EC:4.6.1.1]
Organism
lgf  Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf00230  Purine metabolism
lgf01100  Metabolic pathways
lgf01522  Endocrine resistance
lgf04015  Rap1 signaling pathway
lgf04020  Calcium signaling pathway
lgf04022  cGMP-PKG signaling pathway
lgf04024  cAMP signaling pathway
lgf04062  Chemokine signaling pathway
lgf04072  Phospholipase D signaling pathway
lgf04081  Hormone signaling
lgf04082  Neuroactive ligand signaling
lgf04114  Oocyte meiosis
lgf04211  Longevity regulating pathway
lgf04213  Longevity regulating pathway - multiple species
lgf04261  Adrenergic signaling in cardiomyocytes
lgf04270  Vascular smooth muscle contraction
lgf04371  Apelin signaling pathway
lgf04540  Gap junction
lgf04611  Platelet activation
lgf04713  Circadian entrainment
lgf04714  Thermogenesis
lgf04720  Long-term potentiation
lgf04723  Retrograde endocannabinoid signaling
lgf04724  Glutamatergic synapse
lgf04725  Cholinergic synapse
lgf04727  GABAergic synapse
lgf04750  Inflammatory mediator regulation of TRP channels
lgf04911  Insulin secretion
lgf04912  GnRH signaling pathway
lgf04913  Ovarian steroidogenesis
lgf04914  Progesterone-mediated oocyte maturation
lgf04915  Estrogen signaling pathway
lgf04916  Melanogenesis
lgf04918  Thyroid hormone synthesis
lgf04921  Oxytocin signaling pathway
lgf04923  Regulation of lipolysis in adipocytes
lgf04925  Aldosterone synthesis and secretion
lgf04926  Relaxin signaling pathway
lgf04927  Cortisol synthesis and secretion
lgf04928  Parathyroid hormone synthesis, secretion and action
lgf04934  Cushing syndrome
lgf04935  Growth hormone synthesis, secretion and action
lgf04970  Salivary secretion
lgf04971  Gastric acid secretion
lgf04972  Pancreatic secretion
lgf04976  Bile secretion
lgf05032  Morphine addiction
lgf05142  Chagas disease
lgf05146  Amoebiasis
lgf05163  Human cytomegalovirus infection
lgf05166  Human T-cell leukemia virus 1 infection
lgf05200  Pathways in cancer
lgf05207  Chemical carcinogenesis - receptor activation
lgf05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lgf00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    123606170 (ADCY1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    123606170 (ADCY1)
   04371 Apelin signaling pathway
    123606170 (ADCY1)
   04020 Calcium signaling pathway
    123606170 (ADCY1)
   04072 Phospholipase D signaling pathway
    123606170 (ADCY1)
   04024 cAMP signaling pathway
    123606170 (ADCY1)
   04022 cGMP-PKG signaling pathway
    123606170 (ADCY1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    123606170 (ADCY1)
   04081 Hormone signaling
    123606170 (ADCY1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    123606170 (ADCY1)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    123606170 (ADCY1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    123606170 (ADCY1)
   04062 Chemokine signaling pathway
    123606170 (ADCY1)
  09152 Endocrine system
   04911 Insulin secretion
    123606170 (ADCY1)
   04923 Regulation of lipolysis in adipocytes
    123606170 (ADCY1)
   04912 GnRH signaling pathway
    123606170 (ADCY1)
   04913 Ovarian steroidogenesis
    123606170 (ADCY1)
   04915 Estrogen signaling pathway
    123606170 (ADCY1)
   04914 Progesterone-mediated oocyte maturation
    123606170 (ADCY1)
   04921 Oxytocin signaling pathway
    123606170 (ADCY1)
   04926 Relaxin signaling pathway
    123606170 (ADCY1)
   04935 Growth hormone synthesis, secretion and action
    123606170 (ADCY1)
   04918 Thyroid hormone synthesis
    123606170 (ADCY1)
   04928 Parathyroid hormone synthesis, secretion and action
    123606170 (ADCY1)
   04916 Melanogenesis
    123606170 (ADCY1)
   04925 Aldosterone synthesis and secretion
    123606170 (ADCY1)
   04927 Cortisol synthesis and secretion
    123606170 (ADCY1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    123606170 (ADCY1)
   04270 Vascular smooth muscle contraction
    123606170 (ADCY1)
  09154 Digestive system
   04970 Salivary secretion
    123606170 (ADCY1)
   04971 Gastric acid secretion
    123606170 (ADCY1)
   04972 Pancreatic secretion
    123606170 (ADCY1)
   04976 Bile secretion
    123606170 (ADCY1)
  09156 Nervous system
   04724 Glutamatergic synapse
    123606170 (ADCY1)
   04727 GABAergic synapse
    123606170 (ADCY1)
   04725 Cholinergic synapse
    123606170 (ADCY1)
   04720 Long-term potentiation
    123606170 (ADCY1)
   04723 Retrograde endocannabinoid signaling
    123606170 (ADCY1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123606170 (ADCY1)
  09149 Aging
   04211 Longevity regulating pathway
    123606170 (ADCY1)
   04213 Longevity regulating pathway - multiple species
    123606170 (ADCY1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    123606170 (ADCY1)
   04714 Thermogenesis
    123606170 (ADCY1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123606170 (ADCY1)
   05207 Chemical carcinogenesis - receptor activation
    123606170 (ADCY1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123606170 (ADCY1)
   05163 Human cytomegalovirus infection
    123606170 (ADCY1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    123606170 (ADCY1)
   05142 Chagas disease
    123606170 (ADCY1)
  09165 Substance dependence
   05032 Morphine addiction
    123606170 (ADCY1)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    123606170 (ADCY1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    123606170 (ADCY1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    123606170 (ADCY1)
Enzymes [BR:lgf01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     123606170 (ADCY1)
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom DUF6688
Other DBs
NCBI-GeneID: 123606170
NCBI-ProteinID: XP_045350173
Position
A2:62320546..62434373
AA seq 1132 aa
MAGAPRGRGGGGGGGGGGAGEPGGAERAARPGGRRGLRACDEEFACPELEALFRGYTLRL
EQAATLKALAVLSGLAGALALAELLGAPGPAAGLARGSHPAHCVLFLALLVVTNVRSLQV
PQLQQVGQLALLFSLTFALLCCPFALGRPAGTLAGAASGPATADQGVWQLLLVTFVSYAL
LPVRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLSVNMYGVFVRILAE
RSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYI
QRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYC
VSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQY
DVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKAHNIETFFI
VPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVLTCEDDDKR
RALRTASEKLRNRSSFSANAVYTTPGTRVNRYIGRLLEARQMELEMADLDFFTLKYKQAE
RERKYHQLQDEYFTSAVVLALVLAALFGLVYLLIIPQNLVLLLLLAFCICFLVACVLYLH
VTRVQCFPGCLTIQIRTVLCIFVVVLIYSVAQGCVVGCLPWSWSSTPNGSLVVLTPSGRN
AVLPAAPCESAPHALLCGLVGTLPLAVFLRVSSLPKMILLFVLTTSYILVLELSGYTRAP
GGGVASGRSFEPIMAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMERVKLDNKR
ILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFDDFYIELDGNNMGVECLR
LLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTTGTKAKKGISSHLSTLADFA
IEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQ
GRIQVTEEVHRLLRRGTYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQARERKVCGYGR
AGLQGRLGTGPPPVSSMAGLPVRAGMGALQGSGLPPCPHSQHLPPGAAGKEA
NT seq 3399 nt   +upstreamnt  +downstreamnt
atggcgggggcgccgcgcggccgaggcggaggcggcggcggaggcggaggcggcgcgggc
gagcccgggggcgcggagcgggcggcccggccgggcggccggcgcgggctgcgggcgtgc
gacgaggagttcgcgtgccccgagctggaggcgctgttccgcggctacacgctgcggctg
gagcaggcggctacgctgaaggcgctggcggtgctcagcgggctggcgggcgcgctggcg
ctggccgagctgctgggcgcgccggggcccgcggccggcctggcccggggctcgcacccc
gcgcactgcgtgctcttcctggcgctgctcgtggtcaccaacgtgcgctcgctgcaggtg
ccccagctgcagcaggtcggccagctggcgctgctcttcagcctcaccttcgcgctgctg
tgctgccccttcgcgctcggccgccccgcggggaccctcgccggcgccgcttcggggccg
gcgaccgccgaccagggcgtgtggcagctcctgctggtcaccttcgtgtcctatgccctg
ctgcccgtgcgcagcctgctggccatcggcttcgggctcgtggtggccgcctcgcacttg
ctggtcacggccaccttggtacccgccaagcgcccgcgtctctggaggacgcttggtgcc
aacgccctgctcttcctcagcgtgaacatgtatggggtgtttgtgcgcatcctggccgag
cgctcccagcggaaagccttcctgcaagcccggaactgcatcgaagatcggctgaggctg
gaggatgagaacgagaagcaggagcggctgctcatgagccttctgccccggaatgttgcc
atggagatgaaggaggacttcctgaagccccccgagaggattttccacaagatttacatc
cagcggcatgacaacgtgagcatcctctttgcggacattgtgggcttcacgggcctggca
tcgcagtgcacggcacaggagctggttaagctcctcaacgagctgttcggcaagtttgat
gaactggccacggagaatcactgtcgccgcatcaagatcctaggggactgttactactgt
gtgtccggcctcacccagcccaagaccgaccacgcccactgctgcgtggagatgggcctg
gacatgatcgacaccatcacgtctgtggccgaggccaccgaggtggacctgaacatgcgt
gtggggctgcacacaggcagggtcctctgcggggtcctgggcctgcgcaagtggcagtac
gacgtgtggtccaacgacgtgaccctggccaacgtcatggaggcggccggcctacctggg
aaggtccacatcacgaagacgaccctagcgtgcctgaacggggactacgaggtggagccg
ggtcatggacacgagaggaacagttttctgaaagctcacaacatcgagaccttcttcatc
gtgccgtcacatcggcggaagatatttccagggctgatcctctctgacataaaaccagcc
aagaggatgaagttcaagaccgtgtgctacctgcttgtgcagctgatgcactgtcggaag
atgttcaaggcagagatcccgttctctaacgtcctgacgtgtgaggacgacgacaagcgg
agggcgctgagaaccgcgtcagagaaactgcgaaaccgctcgtcgttctccgcaaacgcc
gtctacaccaccccgggcacgcgcgtcaacaggtacatcggccgcctcctggaagcgcgc
cagatggagctggagatggcggacctggacttcttcaccctcaagtacaagcaggctgag
cgggagcgcaagtaccaccagcttcaggacgagtattttaccagcgctgtcgttctggcc
ctcgtcctggccgccttgtttggcctcgtctacctgctcatcatcccacagaacctggtc
ctcctgctgctgctggccttctgtatctgcttcctggtggcctgcgtcctgtacctgcac
gtcacccgggtccagtgttttccagggtgcctgacgattcagatccgcaccgtcttgtgt
atcttcgtcgtggtcttaatctactccgtggcccaaggatgtgtggtgggctgcctgccc
tggtcctggagctccacccccaacgggtccctggtggtcctgacgcccagcggccgcaac
gctgtgctgcctgccgcgccctgtgagtcggcgccccacgccctgctctgcggccttgtg
ggtaccctcccgctggctgtcttcctgcgggtgtcctccctgcccaaaatgatcctgctc
tttgtgctcacgacgtcctacatcctggtcctggagctcagcggctacaccagggccccc
gggggcggcgtggcgtcggggcgcagtttcgagccgatcatggccatcctgctgttttcc
tgcaccctggccctgcacgcccgtcaggtggacgtcaagctgcggctggactacctctgg
gcggcacaggcagaggaggagagagacgacatggagagggtgaagttggacaacaagagg
attctcttcaacctcctgccggcccacgtggctcagcacttcctcatgtccaacccccgc
aacatggacctgtactaccagtcctactcacaggtgggcgtcatgtttgcttccatcccc
aacttcgacgacttctacatcgagctggacggcaacaacatgggggtggagtgtctgcgt
ctcctgaacgagatcatcgcagacttcgacgagctcatggacaaagacttttacaaggac
ttggagaagatcaagaccatcgggagcacctacatggccgctgtggggctggcgcccacc
actgggaccaaggccaagaagggcatctcctcccacctgagcacactggccgacttcgcc
atcgagatgttcgacgtcctggatgaaatcaactaccagtcttacaacgactttgtgctc
cgtgtgggcatcaacgtgggccctgtggtggccggggtgattggggctcggaggccgcag
tacgacatctgggggaacacggtcaacgtggccagtcggatggacagcaccggtgtccag
ggcagaatccaggtgaccgaggaggttcaccggctgctgcgccgggggacctaccgcttc
gtgtgccgcgggaaggtcagcgtcaagggcaagggtgagatgctgacgtacttcctggaa
ggcaggacggacggaaacggctcccaagccagggagcggaaagtgtgtggctacgggcga
gccggcctccagggcagactgggcacgggcccgcccccggtgtcctccatggctggcctc
cctgtcagagccgggatgggggctctgcagggctcagggctccccccctgcccccacagc
cagcacctgcctcccggagcagctgggaaggaggcttag

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (4)   
   Pfam (4)   
All databases (10)   

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