KEGG   Leopardus geoffroyi (Geoffroy's cat): 123609628
Entry
123609628         CDS       T10761                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
lgf  Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf01522  Endocrine resistance
lgf04010  MAPK signaling pathway
lgf04015  Rap1 signaling pathway
lgf04068  FoxO signaling pathway
lgf04071  Sphingolipid signaling pathway
lgf04114  Oocyte meiosis
lgf04148  Efferocytosis
lgf04218  Cellular senescence
lgf04261  Adrenergic signaling in cardiomyocytes
lgf04370  VEGF signaling pathway
lgf04380  Osteoclast differentiation
lgf04550  Signaling pathways regulating pluripotency of stem cells
lgf04611  Platelet activation
lgf04613  Neutrophil extracellular trap formation
lgf04620  Toll-like receptor signaling pathway
lgf04621  NOD-like receptor signaling pathway
lgf04622  RIG-I-like receptor signaling pathway
lgf04625  C-type lectin receptor signaling pathway
lgf04657  IL-17 signaling pathway
lgf04658  Th1 and Th2 cell differentiation
lgf04659  Th17 cell differentiation
lgf04660  T cell receptor signaling pathway
lgf04664  Fc epsilon RI signaling pathway
lgf04668  TNF signaling pathway
lgf04670  Leukocyte transendothelial migration
lgf04714  Thermogenesis
lgf04722  Neurotrophin signaling pathway
lgf04723  Retrograde endocannabinoid signaling
lgf04728  Dopaminergic synapse
lgf04750  Inflammatory mediator regulation of TRP channels
lgf04912  GnRH signaling pathway
lgf04914  Progesterone-mediated oocyte maturation
lgf04917  Prolactin signaling pathway
lgf04926  Relaxin signaling pathway
lgf04932  Non-alcoholic fatty liver disease
lgf04933  AGE-RAGE signaling pathway in diabetic complications
lgf04935  Growth hormone synthesis, secretion and action
lgf04936  Alcoholic liver disease
lgf05014  Amyotrophic lateral sclerosis
lgf05020  Prion disease
lgf05022  Pathways of neurodegeneration - multiple diseases
lgf05132  Salmonella infection
lgf05133  Pertussis
lgf05135  Yersinia infection
lgf05140  Leishmaniasis
lgf05142  Chagas disease
lgf05145  Toxoplasmosis
lgf05152  Tuberculosis
lgf05161  Hepatitis B
lgf05163  Human cytomegalovirus infection
lgf05167  Kaposi sarcoma-associated herpesvirus infection
lgf05169  Epstein-Barr virus infection
lgf05170  Human immunodeficiency virus 1 infection
lgf05171  Coronavirus disease - COVID-19
lgf05205  Proteoglycans in cancer
lgf05208  Chemical carcinogenesis - reactive oxygen species
lgf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
lgf05415  Diabetic cardiomyopathy
lgf05417  Lipid and atherosclerosis
lgf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lgf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123609628 (MAPK14)
   04015 Rap1 signaling pathway
    123609628 (MAPK14)
   04370 VEGF signaling pathway
    123609628 (MAPK14)
   04668 TNF signaling pathway
    123609628 (MAPK14)
   04068 FoxO signaling pathway
    123609628 (MAPK14)
   04071 Sphingolipid signaling pathway
    123609628 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    123609628 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    123609628 (MAPK14)
   04218 Cellular senescence
    123609628 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    123609628 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    123609628 (MAPK14)
   04613 Neutrophil extracellular trap formation
    123609628 (MAPK14)
   04620 Toll-like receptor signaling pathway
    123609628 (MAPK14)
   04621 NOD-like receptor signaling pathway
    123609628 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    123609628 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    123609628 (MAPK14)
   04660 T cell receptor signaling pathway
    123609628 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    123609628 (MAPK14)
   04659 Th17 cell differentiation
    123609628 (MAPK14)
   04657 IL-17 signaling pathway
    123609628 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    123609628 (MAPK14)
   04670 Leukocyte transendothelial migration
    123609628 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    123609628 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    123609628 (MAPK14)
   04917 Prolactin signaling pathway
    123609628 (MAPK14)
   04926 Relaxin signaling pathway
    123609628 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    123609628 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    123609628 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    123609628 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    123609628 (MAPK14)
   04722 Neurotrophin signaling pathway
    123609628 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123609628 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123609628 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    123609628 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    123609628 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    123609628 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123609628 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123609628 (MAPK14)
   05161 Hepatitis B
    123609628 (MAPK14)
   05171 Coronavirus disease - COVID-19
    123609628 (MAPK14)
   05163 Human cytomegalovirus infection
    123609628 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123609628 (MAPK14)
   05169 Epstein-Barr virus infection
    123609628 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123609628 (MAPK14)
   05135 Yersinia infection
    123609628 (MAPK14)
   05133 Pertussis
    123609628 (MAPK14)
   05152 Tuberculosis
    123609628 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123609628 (MAPK14)
   05140 Leishmaniasis
    123609628 (MAPK14)
   05142 Chagas disease
    123609628 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    123609628 (MAPK14)
   05020 Prion disease
    123609628 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    123609628 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123609628 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    123609628 (MAPK14)
   05415 Diabetic cardiomyopathy
    123609628 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123609628 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    123609628 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123609628 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    123609628 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lgf01001]
    123609628 (MAPK14)
Enzymes [BR:lgf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     123609628 (MAPK14)
Protein kinases [BR:lgf01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   123609628 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 123609628
NCBI-ProteinID: XP_045356745
Position
B2:34790639..34866513
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGADLLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaggagctgaacaagacaatctgggaggtg
ccggagcgttaccagaacctgtccccggtgggctccggtgcctatggctccgtgtgtgct
gcctttgacacaaaaactgggttacgtgtggcagtgaagaagctctccagaccgtttcag
tccatcattcatgccaaaaggacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggatgtttttacacctgcaaggtctctggaggaattcaat
gatgtgtatctggtgacccatctcatgggagcagatctgaacaacattgtgaaatgtcag
aagcttacggatgaccatgttcagttccttatctaccagattctccgaggtctcaagtat
atacattcagctgacataattcacagggacctgaaacctagtaatctagctgtgaatgaa
gactgtgagctgaagatcttggattttggactggctcgacatacagatgatgaaatgaca
ggctatgtggccactaggtggtacagggctcctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaaga
acgttgtttcctggtacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgatcttttgaagaaaatctcctcagagtctgcaagaaactacattcag
tctttgacccagatgccgaaaatgaactttgcaaatgtatttattggtgccaatcccttg
gcggtggacttgctggagaagatgcttgtactggactcagacaagagaatcacagcggcc
caagcacttgcacacgcctactttgcccagtaccatgatcctgatgatgaaccagtggct
gatccttatgatcagtcctttgaaagcagggacctccttatagatgaatggaagagcctg
acctacgatgaagtcatcagctttgtgcccccaccccttgaccaagaagagatggaatcc
tga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (7)   
   RefSeq(nuc) (7)   
Protein domain (6)   
   Pfam (6)   
All databases (20)   

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