KEGG   Leopardus geoffroyi (Geoffroy's cat): 123609637
Entry
123609637         CDS       T10761                                 
Symbol
APC
Name
(RefSeq) adenomatous polyposis coli protein isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
lgf  Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf04310  Wnt signaling pathway
lgf04390  Hippo signaling pathway
lgf04519  Cadherin signaling
lgf04550  Signaling pathways regulating pluripotency of stem cells
lgf04810  Regulation of actin cytoskeleton
lgf04934  Cushing syndrome
lgf05010  Alzheimer disease
lgf05022  Pathways of neurodegeneration - multiple diseases
lgf05165  Human papillomavirus infection
lgf05200  Pathways in cancer
lgf05206  MicroRNAs in cancer
lgf05210  Colorectal cancer
lgf05213  Endometrial cancer
lgf05217  Basal cell carcinoma
lgf05224  Breast cancer
lgf05225  Hepatocellular carcinoma
lgf05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:lgf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    123609637 (APC)
   04390 Hippo signaling pathway
    123609637 (APC)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    123609637 (APC)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    123609637 (APC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    123609637 (APC)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123609637 (APC)
   05206 MicroRNAs in cancer
    123609637 (APC)
  09162 Cancer: specific types
   05210 Colorectal cancer
    123609637 (APC)
   05225 Hepatocellular carcinoma
    123609637 (APC)
   05226 Gastric cancer
    123609637 (APC)
   05217 Basal cell carcinoma
    123609637 (APC)
   05213 Endometrial cancer
    123609637 (APC)
   05224 Breast cancer
    123609637 (APC)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    123609637 (APC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123609637 (APC)
   05022 Pathways of neurodegeneration - multiple diseases
    123609637 (APC)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    123609637 (APC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:lgf01009]
    123609637 (APC)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:lgf03036]
    123609637 (APC)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:lgf04812]
    123609637 (APC)
Protein phosphatases and associated proteins [BR:lgf01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     123609637 (APC)
Chromosome and associated proteins [BR:lgf03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    123609637 (APC)
Cytoskeleton proteins [BR:lgf04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     123609637 (APC)
SSDB
Motif
Pfam: Arm_APC_u3 APC_basic EB1_binding APC_r APC_u5 APC_u14 APC_rep APC_u15 APC_u9 SAMP Arm APC_u13 APC_15aa Suppressor_APC ARM_ARMC5 ZER1-like_2nd Sec7-like_HUS
Other DBs
NCBI-GeneID: 123609637
NCBI-ProteinID: XP_045356774
Position
A1:172024725..172172234
AA seq 2871 aa
MYACLGSGPVAVLPASAPPSTLGSWSSGGGGGGRVPQERKRPGGVRTSGRGANVWQEVLK
QLQGSIEDEAMASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGE
CSPVPMGSFPKRGFVNGSRENTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRI
DSLPLTENFSLQTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRVTRIQQIEKDIL
RIRQLLQSQATEAERSSQSKHEAGSHEAERQNEGQGVAEINMATPGSGQGSAARMDHETA
SVLSSSSTHSAPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQ
SGCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHL
LEQIRAYCETCWEWQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNEL
GRKATRGISSQELGQGLAGGLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFG
DVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKA
LMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAI
IESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARN
PKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSSLPS
LHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRSKQRHKPNLYGDYVFDTNRHDDNRS
DNFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGISLGNYHPATENPG
TSSKRGLQISTTAAQIAKVMEEVSAIHTSQEDRSSGSTGELHCGTDERNALRRSSTAHTH
ANTYNFTKSENSNRTCPMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDE
SKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWAR
PKHIIEDEIKQSEQRQSRSQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGANGSE
TNRVSSNHGINQNVNQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKH
HVDQPIDYSLKYATDIPASQKPPFSFSKSSSGQSTKTEHISSSSENTSTPSSNAKRQNQH
HPSSTQSRSGQTPKATSCKVPSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCDQ
TTQETDSANTLQIAEIKENSGTRSTEESVSEVPTVSQHIRTKSSRLQASGLSAESTRHKA
VEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCS
GMVSGIISPSDLPDSPGQTMPPSRSKTPPPQTVQSKREVPKNKAPTAEKRESGPKQAAVN
AAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDN
GNETESEQPEEANESQVKEAEKPTDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKK
PAQTAPKLPPPVARKPSQLPVYKLLPSQNRLQAQKHVSFTPGDDMPRVYCVEGTPINFST
ATSLSDLTIESPPNELAAGEGVRAGAQSGEFEKRDTIPTEGRSTDDAQRVKTPSATISEL
DDNKTEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASISSSGANKNQLDGKKKKPT
SPVKPIPQNTEYRTRVRKNTDSKNNLNAERTFSDNKDSKKQNLKNNSKDFNDKLPNNEDR
VRGSFTFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKGKENKESEAK
VTSHTELTSSQQSANKTQAVTKHPINRGQSKPMLQKQSTFPQSSKDIPDRGAATDEKLQN
FAIENTPVCFSRNSSLSSLSDIDQENNNNKEGEPVKETEPPDSQGEPSKPQASGYAPKSF
HVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNTSGIL
AEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDS
DSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESENKGIKGGK
KVYRSLITGKVRSNSEISSQMKQPLQTNMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPP
LKTPASKSPSEGQPATTSPRGTKPSVKSELSPVTRQTSQPAGANKGSSRSGSRDSTPSRP
AQQPLSRPMQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQ
MSQQNLTKQTGLSKNGSSIPRSESASKGLNQMNNGNGSNKKVELSRMSSTKSSGSESDRS
ERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPDSPTRSQAQTPVLSPSLPDMS
LSTHSSVQSGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHS
KHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQTKENQVSTKGTW
RKIKENEISPTNSTSQTTSSGAANGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSG
RSPTGNTPPVIDTVSEKGNPNAKDSKDNQGKQNVGNGSAPIRTMGLENRLNSFIQVDAPD
QKGTEAKPGQSNPVPVSETNESSIAERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRK
SSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTSV
NT seq 8616 nt   +upstreamnt  +downstreamnt
atgtacgcctgtctgggctcgggtccggtcgccgttttgcctgcttctgcaccaccctct
actctcgggtcctggagctccggcggcggcggcggcggccgtgtcccgcaggagaggaag
cgcccaggcggcgtccgtacttctggccgcggggcgaacgtctggcaggaagtacttaaa
cagctacaaggaagtattgaagatgaagctatggcttcttctggacagattgatttatta
gagcgtctcaaagaacttaatttagatagcagtaatttccctggagtgaaactacgctca
aaaatgtccctccgttcttatggaagccgcgaaggatctgtatctagtcgttcaggagag
tgcagtcctgttcctatgggttcgtttccaaaaagagggtttgtaaatggaagcagagaa
aatactggttatttagaagaacttgagaaagaaagatcattacttcttgctgatcttgac
aaagaagaaaaggaaaaagactggtattatgctcaacttcagaatctcactaaaagaata
gatagtcttcctttaactgaaaatttttccttacaaacagatatgaccagaagacaattg
gaatatgaagcaaggcaaatcagagttgcaatggaagaacaactaggtacttgccaggat
atggagaaaagagcacagcgaagagtaaccagaattcaacaaatagagaaggacatactt
cgtatacgacagcttttacagtcccaagccacagaagcagagaggtcatctcagagcaag
catgaagccggctcacatgaagctgagcggcagaatgaaggtcaaggagtggcagaaatc
aacatggcaactcctggtagtggtcagggttcagctgcacgaatggatcatgaaacagcc
agtgttttgagttctagtagcacacactctgctcctcgaaggctgacaagtcatctggga
accaaggtggaaatggtgtattcattgttatcaatgcttggtactcatgataaggatgat
atgtcgcgaactttgctagctatgtctagctcccaagacagctgtatatccatgcgacag
tctggatgtcttcctctcctcatccagcttttacatggcaatgacaaagactctgtgttg
ttgggaaattcccggggcagtaaagaggctcgggccagggccagtgcagcacttcacaac
atcattcactcacagcctgatgacaagagaggcaggcgtgaaatccgagtccttcatctt
ttggaacagatacgagcttactgtgaaacctgttgggagtggcaggaagcccatgaacaa
ggcatggaccaggacaaaaatccaatgccagctcctgttgaacatcagatctgtcctgct
gtgtgtgttctaatgaaactttcatttgatgaagaacatagacatgcaatgaatgaactt
ggtaggaaggctacccggggcatttcatcacaggagctagggcaggggcttgcaggggga
ctacaggccattgcagaattattgcaggtggactgtgaaatgtatgggctaactaatgac
cactacagtattacattaagacgatatgctggaatggctttgacaaacttgacttttgga
gatgtagccaacaaggctacactctgctctatgaaaggctgcatgagagcacttgtggcc
caactaaaatctgaaagtgaagacttacagcaggttattgcaagtgttttgaggaatttg
tcttggcgagcagatgtaaatagtaaaaagacattgcgcgaagttggaagtgtgaaagca
ttaatggaatgtgctttggaagttaaaaaggaatcaaccctcaaaagcgtattgagtgcc
ttatggaatttgtcagcacattgcactgagaataaagctgatatatgtgctgtagatggt
gcgcttgcatttctggttggcactctcacttaccgaagccagacaaatactttagccatt
attgaaagtggaggtggaatattacggaacgtgtccagcttgatagctacaaatgaggac
cacaggcaaatcctaagagagaacaactgcctgcaaaccttattacaacacttgaaatct
cacagtttgacaatagtcagtaatgcatgtggaaccttgtggaatctctcagcaagaaat
cctaaagaccaggaagcattatgggacatgggggcagtcagcatgctcaagaacctcatt
cattcaaagcacaaaatgattgctatgggaagcgctgcagctttaaggaatctcatggca
aatagacctgcaaagtataaggatgccaatataatgtctcctggttcaagcttgccatct
cttcatgtcaggaaacaaaaagccctagaagcagaattagatgctcagcatttatcagaa
acttttgacaatattgacaatttaagtcccaaggcatctcatcgtagtaagcaacgacac
aagccaaatctttatggtgactatgtttttgacaccaaccgacatgatgataatagatca
gacaattttaatactggaaacatgactgtcctttcaccatatttaaatactacagtgttg
cccagctcctcttcatcaagaggaagtttagacagttctcgttctgaaaaagatagaagt
ttggagagagaacgaggaattagcctaggcaactaccacccagcaacagaaaatccaggc
acttcttcaaagcgaggtttgcagatttccaccactgcagcccagattgccaaagtcatg
gaagaagtatcagccattcacacctcccaggaagacagaagttctgggtctactggcgag
ttacattgtgggacagatgagaggaatgcactaagaagaagctccactgcccacacacat
gcaaacacttacaacttcactaagtcagaaaattcaaataggacatgtcctatgccttat
gccaaattggaatataagagatcttcaaatgatagtttaaatagtgtcagtagtagtgat
ggttatggtaaaagaggtcagatgaagccttccattgaatcctattctgaagatgatgaa
agtaaattttgcagctatggtcagtatccagctgacctagcccataaaatacacagcgca
aatcatatggatgataatgatggagaactagatacaccaataaattatagtcttaaatat
tcagatgagcagttgaactccggaaggcaaagcccttcacagaatgaaagatgggcaaga
cccaaacatataatagaagatgaaataaaacagagtgagcaaagacaatcaagaagtcaa
agcacaacttaccccgtatatactgagagcactgatgataaacatctcaagtttcagcca
cattttggacagcaggaatgtgtttccccatataggtcaagaggagccaatggttcagaa
acaaatcgagtaagttccaatcatggaattaatcaaaatgtaaaccagtctttgtgtcag
gaagatgactatgaagatgataagccaaccaactatagtgaacgttactccgaggaagag
cagcatgaagaagaagagagaccaacaaattatagcataaagtataatgaagagaaacat
catgtggatcaacctatcgattatagtttaaaatatgccacagacattcctgcctcacag
aaaccaccattttcattctcaaagagttcatctggacaaagcactaaaactgaacacatc
tcttcaagcagtgagaatacatccacaccttcatctaatgccaagaggcagaatcagcac
catccaagttccacacaaagcagaagtggtcagaccccaaaagccacctcctgcaaagtt
ccctctatcaaccaagaaacaatacagacttactgtgtagaggataccccaatatgtttc
tcacgttgcagttcactatcatctttgtcatcggccgaagatgaaataggatgtgatcag
acaacacaggaaacagattctgctaatactctacaaatagcagaaataaaagaaaacagt
gggactagatcaacagaagagtctgtgagtgaagttccaacagtgtcacagcacattaga
accaaatccagcagacttcaggcttctggtttatctgcagaatcgaccaggcataaagct
gttgaattttcttcaggggctaaatctccatcaaaaagtggtgctcagacacctaaaagt
ccaccagagcactacgttcaggagactccactcatgtttagcagatgcacttctgtcagt
tcacttgatagttttgagagtcgttcgattgccagctccgttcagagtgaaccctgcagt
ggaatggtaagtggcattataagccccagtgaccttccagatagccctggacaaaccatg
ccaccaagcagaagtaaaacccctcctcctcagacagttcagagtaagcgagaggtacct
aaaaacaaagcccctactgcggaaaagagagagagtggaccgaagcaagctgctgtaaat
gctgcagtacagagagtccaggtgcttccagatgctgatactctcttacattttgccaca
gaaagtactccagatggattttcttgttcatctagcctgagtgctctgagcctcgatgag
ccatttatacagaaagatgtggaattaagaataatgcctccagttcaggaaaatgacaat
gggaatgaaaccgaatctgagcagcctgaagaagcaaatgaaagccaggtaaaagaagca
gaaaaacctactgattctgaaaaagatctgttagatgactcagatgatgatgatattgaa
atattagaagaatgtattatttctgccatgccaacaaaatcttcacgtaaagccaaaaaa
ccagcccagactgctccaaaattacctccacctgtggcaaggaaaccaagtcaactccct
gtgtataaacttcttccatcacaaaacaggttacaggcacaaaaacatgttagttttaca
ccaggagatgatatgccacgggtgtattgtgtagaagggacacctataaacttttccaca
gctacatctttaagtgatctaacaatagaatctcctccaaatgagttagctgctggagaa
ggggttagagcaggagcacagtctggtgaatttgaaaaacgagataccattcctacagaa
ggcagaagtacagatgatgctcaaagagtaaaaaccccatctgcaactatatctgaactg
gatgacaataaaacagaagaaggtgatattcttgcagaatgcattaactctgctatgccc
aaaggaaaaagtcacaagcctttccgtgtgaagaagataatggaccaggtccaacaagca
tctatatcttcatctggagctaacaaaaatcagttagatggtaagaaaaagaaacctact
tcaccagtaaaacctataccacaaaatactgaatataggacacgtgtaagaaaaaacaca
gactcaaaaaataatttaaatgctgaaagaactttctcagacaacaaagattcaaagaaa
cagaacttgaaaaataattccaaggatttcaatgataagctaccaaataatgaagatcga
gtcagaggaagttttacttttgattcacctcatcattacactcccattgaaggaactcca
tactgtttttcacgaaatgattctttgagttctctagattttgatgatgatgatgttgac
ctttctagagaaaaggctgaattaagaaaggggaaagaaaataaagaatcagaagctaaa
gttaccagccacacagaactaacctctagccaacaatcagctaataagacacaagctgtt
acaaaacatccaataaatcgaggtcagtcgaaacccatgctgcagaagcaatccactttt
ccacagtcatccaaagacataccagacaggggagcagcaactgatgagaaattacaaaat
tttgctattgaaaatactccggtgtgcttttctcgaaattcctctttaagttctcttagt
gacattgatcaagaaaacaacaataacaaagaaggtgaacctgtcaaagagacagagccc
cctgactcacagggagaacccagcaaacctcaggcatcaggttatgctcctaaatcattt
catgttgaagatacccctgtttgtttctcacgaaatagttctctcagttctcttagtatt
gattctgaagatgacctgttgcaggaatgtataagttctgcaatgccaaaaaagaaaaag
ccttcaagactcaagggtgataatgaaaagcatagtcccagaaatacgagtggcatattg
gcagaagatttgacacttgatttgaaagatatacagagaccagattcagaacatggttta
tccccggattcagaaaattttgattggaaagctattcaggaaggtgcaaattccatagta
agtagtttacatcaagctgctgctgctgcatgtttatctagacaggcatcatctgactca
gactccatcctttcactgaaatcagggatctccctgggatcaccatttcatcttacacct
gatcaagaggaaaaaccctttacaagtaataagggcccacgaattctaaaacctggggag
aagagtacattggaaactaaaaagatagaatctgaaaataaaggaatcaaaggaggaaaa
aaagtttatagaagtttaattaccggaaaagttcgttctaattcagaaatttcaagccaa
atgaaacagcctcttcaaacaaacatgccttcaatctctcggggcaggacaatgattcat
attccaggagttcgaaatagctcttcaagtacaagtccggtttctaaaaaaggcccaccc
cttaagactccagcctccaaaagccctagtgaaggtcagccagccaccacttctcctaga
ggaaccaagccatctgtgaagtcagaattaagccctgttaccaggcagacatcccaacca
gctggagcaaataaagggtcttctagatcaggatctagagattccactccttcaagacct
gcccaacaaccattaagtagacctatgcagtctccggggcggaactcaatttctcctggt
cgaaatggaataagccctcctaataaattatcccagttgccaaggacttcatcccctagt
actgcttcaactaagtcctcaggttctgggaagatgtcatacacatctccaggcagacag
atgagccagcagaaccttaccaaacaaacgggtttatccaagaatggcagcagtatccca
agaagtgagtctgcctccaaaggactaaatcagatgaataatgggaatggatccaataaa
aaggtagaactttctagaatgtcctcaactaaatcaagtggaagtgaatctgataggtca
gagagacccgtattagtacgccagtcaactttcatcaaagaagctccaagcccaacccta
aggagaaaattggaggaatctgcttcatttgaatctctttctccatcttctagaccagat
tctcccactaggtcccaggcacagactccagttttaagtccttcccttcctgatatgtct
ctgtccacacattcatctgttcagtctggtggatggcgaaaactcccacctaatctcagt
cccaccatagagtataatgatggaagaccagcaaagcgccatgatatagcacgctcccat
tctgaaagtccttctagacttccaattaataggtcaggaacctggaaacgtgagcacagc
aaacattcatcatcccttccacgagtaagcacttggagaagaactggaagttcatcctca
attctttctgcttcatcagaatccagtgaaaaagcaaaaagtgaagatgaaaaacatgtg
aactctatttcaggaaccaaacaaactaaagaaaaccaagtatccacaaaaggaacatgg
agaaaaataaaagaaaatgagatttctcccacaaatagtacctctcagaccacttcctca
ggtgctgcaaatggtgctgaatcaaagactctgatttatcaaatggcacctgctgtttct
aaaacagaggatgtttgggtgagaattgaggactgtcccatcaacaaccctagatccgga
agatccccaacaggaaatactccccccgtgattgacactgtttcagaaaagggaaatcca
aacgctaaagattcaaaagataatcagggaaaacaaaatgtgggtaatggcagtgctccc
atacgcaccatgggtttggaaaaccgcctgaactcctttattcaggtagatgccccagac
caaaaaggaactgaggctaaaccgggacaaagtaaccctgtccctgtgtcagaaactaat
gaaagttccatagctgagcgtacccctttcagttctagcagttcaagcaagcacagttca
cctagtgggactgttgctgccagagtgactccgtttaactacaatccaagccctaggaaa
agcagcgcagatagcacttcagctcggccatctcagatcccgacaccagtgaacaacaac
acgaagaaacgagattcaaaaactgacagcacagaatccagtggaactcaaagtcctaag
cgccattctgggtcttaccttgtgacatctgtttaa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (12)   
   RefSeq(pep) (12)   
DNA sequence (12)   
   RefSeq(nuc) (12)   
Protein domain (17)   
   Pfam (17)   
All databases (43)   

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