KEGG   Lutra lutra (Eurasian river otter): 125088522
Entry
125088522         CDS       T08100                                 
Name
(RefSeq) adenomatous polyposis coli protein 2-like isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
llv  Lutra lutra (Eurasian river otter)
Pathway
llv04310  Wnt signaling pathway
llv04390  Hippo signaling pathway
llv04519  Cadherin signaling
llv04550  Signaling pathways regulating pluripotency of stem cells
llv04810  Regulation of actin cytoskeleton
llv04934  Cushing syndrome
llv05010  Alzheimer disease
llv05022  Pathways of neurodegeneration - multiple diseases
llv05165  Human papillomavirus infection
llv05200  Pathways in cancer
llv05206  MicroRNAs in cancer
llv05210  Colorectal cancer
llv05213  Endometrial cancer
llv05217  Basal cell carcinoma
llv05224  Breast cancer
llv05225  Hepatocellular carcinoma
llv05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:llv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    125088522
   04390 Hippo signaling pathway
    125088522
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    125088522
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    125088522
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    125088522
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    125088522
   05206 MicroRNAs in cancer
    125088522
  09162 Cancer: specific types
   05210 Colorectal cancer
    125088522
   05225 Hepatocellular carcinoma
    125088522
   05226 Gastric cancer
    125088522
   05217 Basal cell carcinoma
    125088522
   05213 Endometrial cancer
    125088522
   05224 Breast cancer
    125088522
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    125088522
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    125088522
   05022 Pathways of neurodegeneration - multiple diseases
    125088522
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    125088522
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:llv01009]
    125088522
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:llv03036]
    125088522
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:llv04812]
    125088522
Protein phosphatases and associated proteins [BR:llv01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     125088522
Chromosome and associated proteins [BR:llv03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    125088522
Cytoskeleton proteins [BR:llv04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     125088522
SSDB
Motif
Pfam: APC_basic APC_rep APC_N_CC Arm Suppressor_APC Arm_APC_u3 APC_r SAMP ARM_PUB SSNA1 ZER1-like_2nd PEA2_C ARM_ARMC5 ENTR1 Sec7-like_HUS bZIP_1 MPS2 Par-4_C PDC10_C Wtap HALZ CCDC138_cc
Other DBs
NCBI-GeneID: 125088522
NCBI-ProteinID: XP_047565697
Position
1:complement(222607094..222632764)
AA seq 2285 aa
MGLWGLLSLLHSAFFGDQALQELKMASSVAPYEQLVRQVEALKAENSHLRQELRDNSSHL
SKLETETSGMKEVLKHLQGKLEQEAGVLVSLGQTDVLEQLKALQMDITSLYNLKFQPPAL
SPEPEARTPEESPVHGSEPSKDSFGELSKATVRLLEELDRERCFLLNEIEKEEKEKLWYY
SQLQGLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRA
SRLEQIDQELLSAQDRVPQTEPQALLAVKSVPVEEDPETEVPTHPDDGVPQPGNSKVEVV
FWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGAEAGAGSPGAPGA
KDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQGRDGADGGGNG
GAPVPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQAVADLLQVDYEMHKMTRDPLNLA
LRRYAGMTLTNLTFGDVANKATLCARRGCMEAIVAQLASESEELHQVVSSILRNLSWRAD
INSKKVLREVGSMTALMQCVLRASKESTLKSVLSALWNLSAHSTENKAAICQVDGALGFL
VSTLTHKCQSNSLAIIESGGGILRNVSSLIATREDYRQVLRDHNCLQTLLQHLTSHSLTI
VSNACGTLWNLSARSPRDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLAHRPAK
YQTTATAVSPGACAPSLYVRKQRALEAELDTRHLAQALDHLEKQGLPEAEADAASKKPLP
PLRHLDGLARDYASDSGCFDDDEAPSLAAAATTAEPASPAVLSLFLGSPFLQGQALARAP
PAPRSVPDAEKEAGREVAVAARAKAKLALAVARIDRLVEDISALHTSSDDSFSLSSGDPG
QEAPREGRAQSCSPCRRPEVRRPEAGSRAHPLVRLKAAHASLSNDSLNSGSTGDGRCPRE
HTRSCPLAVLAEHREGSPSSQVRPSQLDLHLPGSQEPASRDGSAPDACVRTIRLSPTYRH
VPLFEGNPRAGMGSLAPGARKQAWLPMDGLSKVPEKLVAETVPLCLSRCSSLSSLSSAGR
PGPSEAGDLDSDSSLEGLEEAGPSKADLDGAWLGPGAASLPVAIPAPQRGRGLGVEDTTP
SSSSENCVQETPLVLSRCSSVSSLSSFESPSIASSVPSDPCSGLGSGTVSPSELPDSPGQ
TMPPSRSKTPPLAPVPPGERESTQFSLQWESYVKRFLDIADRRERCRLPSELDAGSVRFT
VEKPDENFSCASSLSALALHEHYVQKDVELRLLPPACPERGGGGGGSGPGLHFAGHRRRD
EAGGCLEGPAAADQELELLRECLGAAVPARLRKVASALVPGRRALPVPVYMLVPAPARAE
DSCADSAEGTPVTFSSSTSLSDETLQGPPRDPPSGHSDRQKPAGREAPARQATGHRHRAW
GAGQSPGQARGVGRSREGLELPLHRPSSAYKDQDVFHPSPGRVDGALQSLCLTTPTEEAV
YCFYDNDSDEEPSEAVVPPRRASAIPRAVKRERPAGKKEVQAAPKATPKATQAARAQPSL
IADEMPPCYSLSSSASSLSEPDPPEHPAGRPQALEPAVSKGPGAAGGCHGPPSPRVETGL
LRRGVNSTVPRRRFQASGLRCRKPQAAQPDKQPAEGPRERGDEAASSDHASDLDSVEWRA
IQEGANSIVTWLHQAAAAATHEASSGSDSILSGSGLSGSSTLQPTLHRKGRRLQAEGRVG
STARPEKRDSALAQHSTSGPEKLRGAQKTACRVPAVLRGRTVIYVPSPAPRAQPKSHPGT
RVAPRKMGPPSPAQPGAPAKTPSPGQQRSRSLHRPGKSSELAALSRPQRSATPPARLAKA
PSSGSSPASPASQPPTRRLPPGAQAAGPLPGPGAALVPQTPTRALLSKQHKTQKSPVRIP
FMQRPARRGPPALARAAPEPGPRGRAAAEGSPGARGGRLGLVRVASARSSGSGSSDRSGF
QRQLTFIKESPGLRRRHSGLSTPEAAPPASQGGSPRRSRPALPAVFLCSSRCDELRAAPR
QVTAPQQAPAARPSERPARRPSSESPSRLPVRTAAAPPEAVKRYASLPHISVARRPDGAA
PGPSADAARRSSDGEARPLPRVAAPGTTWRRIRDEDVPHILRSTLPATALPLMGAPSKEG
LSGPPQRKTSDAVVQTEDFAATKTNSSTSPSLESRGPPQAPVSGPSTLTSSDVDGLGPTK
APTSAPFVHEGLGVAAGGFPASRHGSPSRSARVPPFNYVPSPMVAATTDLATEKAPTAAP
ASLLE
NT seq 6858 nt   +upstreamnt  +downstreamnt
atggggctctgggggctgctgagcctgctacactcggccttcttcggggaccaggcgctc
caggagctgaagatggcgagctccgtggcaccctacgagcagctggtgcggcaggtggag
gccttgaaggccgagaacagtcatctgaggcaggagcttcgagacaattccagccacctg
tccaagctagagacggagacgtccggcatgaaggaggtcctgaagcacttacagggcaag
ctggagcaagaggccggagtgctggtgtccttggggcagacagatgtgctggagcagctg
aaagccctacagatggacatcaccagcctgtacaacctcaagttccaacccccggcccta
agccccgagcccgaggcgcggacccctgaagaaagtcccgtccacggctctgaaccctct
aaggacagttttggggagctgagcaaggctactgtcaggctgctggaggagctggaccgg
gaacggtgcttcctgttgaacgagatcgagaaggaggagaaggagaagctctggtactac
tcgcagctgcagggcctgtccaagcgcctggacgagctcccgcacgtggagacgcagttc
tcgatgcagatggacctgatccggcagcagctggagttcgaggcccagcacatccgctcg
ctgatggaggagcgcttcggcacctccgacgagatggtgcagcgcgcgcagatccgcgct
tcgcgcctggagcagatcgatcaggagctgctgtccgcccaggaccgcgtgccgcagacc
gagccccaggccctgctggcggtgaagtcagtgccggtagaggaggacccggagactgag
gtccccacgcaccctgacgatggtgtccctcagccgggcaacagcaaggtggaggtggtc
ttctggttgctgtccatgctggcgacacgggaccaggaggacacagcccgcaccctgctg
gcgatgtccagctcgccggagagctgcgtggcgatgcgtcgctcggggtgtctgccactg
ctgctgcagatcctgcatggtgccgaggcgggcgctgggagccccggggcgccgggagcc
aaggatgcacgcatgcgcgccaacgcggcgctgcacaacatagtcttctcgcagccggac
cagggcctggcgcgcaaggagatgcgcgtcctgcatgtgttggagcagatccgggcctac
tgcgagacctgctgggactggctgcagggcagggacggcgccgatggaggcggcaacggc
ggtgcccccgtccccattgagcctcagatctgccaggccacctgtgccgtgatgaagctg
tcctttgatgaggagtaccgccgtgccatgaacgagctgggtgggctgcaggccgtcgcg
gacttgctgcaggttgactacgagatgcacaagatgacgcgggacccgctcaaccttgcc
cttcgccgctatgccggcatgaccctcaccaacctcacctttggggacgtcgccaacaag
gcaacgctgtgtgcccgccggggctgcatggaggccatcgtggcccagctggcttctgag
agcgaggagctccaccaggtggtgtccagcatcctgcgcaacctgtcctggagggctgac
atcaacagcaagaaggtgctgagggaggtcggcagcatgactgccctgatgcagtgtgtt
cttcgagcctccaaggagtccaccctgaagagcgtgctcagtgccctgtggaacctgtca
gcacacagcacggagaacaaggcggccatctgccaggtggacggtgccctgggcttcctg
gtgagcacactgacccacaagtgccagagcaactccctggccatcatcgagagtggtggc
ggcatcctgcgcaacgtgtccagcctcattgccacccgggaggactacaggcaggtgctg
cgggaccacaactgtctgcagacgctgctccagcacctgacgtcgcacagcctgaccatc
gtgagcaacgcctgcggcacgctctggaacctatccgcccgcagcccgcgtgaccaagag
ctcctgtgggacctgggagccgtgggcatgctgcgcaacctggtgcactccaagcacaag
atgatcgccatgggcagcgccgccgccctgcgtaacctgctggcccaccgccccgccaag
taccagaccacagccacggccgtctcccctggcgcatgcgctcccagcctgtacgtgcgg
aagcagcgggcgctggaggccgagctggacacgcggcatctggcgcaggcgctcgaccac
ctggagaagcagggcctgccggaggcggaggccgacgcagcctccaagaagcccctgccg
cccctgcggcacctggacgggctggcccgggactacgcctctgactccggctgcttcgat
gacgacgaggcgccctccctggccgctgcagccaccaccgcggagcctgccagccccgcg
gtgctgtcactcttcctggggagccccttcctgcaggggcaggcgctggcccgggccccg
ccagccccccgcagtgtgccagacgcagagaaggaggccggcagggaggtggccgtggcg
gccagagccaaggccaagctggcgctggcggtggcacgtatcgacaggctggtggaggac
atctccgccctgcacacctcgtcggacgacagcttcagcctcagctctggggaccctggg
caggaagcgccacgtgaaggccgggcccagtcctgctctccttgccggcggccggaggtc
aggcggccagaggctggcagtcgggcccacccactggtgcggctcaaggctgcccacgcc
agcctctccaatgacagcctcaacagcggcagcaccggtgacggacgctgtccccgtgag
cacacacggtcctgcccgctggccgtgctggccgagcaccgtgaggggtccccgagcagc
caggtgcggcccagccagcttgacctccacctgccgggcagccaggagccggcatcccgg
gacggctctgcccccgacgcctgtgtgcgcaccatcaggctgtcgcccacctaccggcac
gtgccactcttcgagggcaaccccagggcgggcatggggtccctggcccccggagcccgg
aagcaggcctggctgcccatggatggcctgagcaaggtgccggagaagctggtggcagag
accgtgccactgtgcctgtcgcgctgcagctccctgtcctcgctgtcctcggctggccgc
ccaggccccagtgaggccggggacctggacagtgactcatccctggaagggctggaggag
gccggacccagcaaggctgacctggacggggcctggcttggccctggggctgcctccctg
cccgtggccatcccggctccccagcggggccggggcctgggggtggaggacaccaccccg
tccagctcctcggagaactgcgtgcaggagacgccgctggtgctgagccgctgcagttcg
gtgagctccctgagcagcttcgagagcccgtccatcgccagctccgtcccgagtgaccca
tgcagcgggctgggcagcggcacggtcagccccagcgagctgcccgacagccccgggcag
accatgccacccagccgcagcaagacgcccccgctagcccccgtgccccccggcgagcgg
gagagcacccagttcagcctgcagtgggagagctacgtgaagcgcttcctggacatcgcc
gaccgccgcgagcgctgccggcttccatccgagctggacgcgggcagcgtgcgcttcacc
gtggagaagccggacgagaacttctcctgcgcctccagcctcagcgcgctggccctgcac
gagcactacgtgcaaaaggacgtggagctgcggctgctgcccccagcctgccccgaacgt
ggcggtggcggcggtggcagcggccccggcctgcactttgcagggcaccgccggcgggac
gaggccggtggctgtcttgagggcccggcagccgctgaccaggaactggagctgctgcgc
gagtgcctgggggcggcagtccccgcccggctccgcaaggtggcctcggcgctggtgcct
ggtcgccgtgcattgcccgtgcccgtctacatgctggtgccggcccctgcccgggcggag
gactcctgcgctgactctgctgagggcacgcccgtcaccttctctagttccacctcgctc
agtgacgagacactgcagggacctcccagggacccacccagcgggcactcggacaggcag
aagcctgcgggtcgcgaggccccggccaggcaggccacggggcacaggcacagggcgtgg
ggtgcgggccagagcccagggcaggcccggggcgtgggcaggagcagggaggggctggag
cttcccctccaccggccctcgagcgcctacaaggaccaggatgtctttcaccccagcccg
ggccgcgtggatggggcgctgcagtccctgtgcctcacgacgcccaccgaggaagccgtg
tactgcttctatgacaacgactcagacgaggagccctccgaggcggtggtgcccccgcgg
cgggcatctgccatcccccgggcggtaaagagagagcgcccagctggcaagaaggaggtg
caggccgcacccaaggctacgcccaaggccacgcaagctgcccgtgcccagcccagcctc
attgccgatgagatgccaccatgctactccctgagctcctccgccagctcccttagtgag
cccgacccccctgagcacccagcaggccggccccaggctctcgagccagctgtcagcaag
gggccaggcgctgcagggggttgtcatggccccccaagcccacgggtggagacagggctg
ctccggcgcggtgtcaactccacggtgcccaggcgccggttccaagcgtcaggccttcgg
tgccgcaagccccaagccgcccagccagacaagcagcctgcagaggggccccgggagcgc
ggggacgaggcggccagctctgaccatgcctccgaccttgacagcgttgagtggcgcgct
atccaggagggcgccaactcaattgtcacgtggctgcaccaggcagcggccgcggccacc
cacgaggcctcatctgggtctgactccatcctgtccgggtcggggctgtcggggagctcc
accctgcaacccacactgcacaggaagggacggcggctgcaggcagagggccgggtgggc
agcaccgcgaggccggagaaacgggactcggccctggcccagcatagcaccagtggcccc
gagaagctgcgtggggctcagaagaccgcgtgcagggtgccagccgtgctccggggaagg
accgtgatttatgtgcccagcccggccccccgggcccaacccaaaagccaccctggcacc
cgtgtggcaccgaggaagatgggacccccgagtcctgcgcagccaggagcccccgccaag
acccccagccccgggcagcagcggtctcgaagcctacaccggccgggcaagagctcggag
ctggcggcgctgagccgtccgcagaggagcgccacaccgcctgcccgcctagccaaggcc
ccctcctcagggtcctcccccgcctctccggcctcccagccccctacaaggaggctgccc
ccaggcgcccaggcagcagggcctctccccggccccggggcagctctggtgccccaaaca
cccacgcgggccctgctgtctaagcagcacaagacgcagaagtcacctgtgcggatcccc
ttcatgcagaggccagccaggcgggggccgccagccctggccagggcagccccggagccg
ggtccccggggtcgggcggcagcggagggaagccctggcgcccgagggggccgcctgggc
ctcgtgcgtgtggcctctgcccgctccagcggcagcgggtcatccgaccgctccggtttc
cagcggcagctgacctttatcaaggagtccccgggcctgcgccgccgccactcgggactg
tccacgccagaggctgcgccccccgcctcccagggcggctcaccccgccgcagtcgaccc
gcgctgcccgccgtcttcctctgctcctcacgctgcgacgagctgcgggcagcccccagg
caggttacagccccccagcaagccccggcggccaggcccagcgagcggcccgcccggcgc
ccgagctccgagagcccgtcccgcctgcctgtccgcacggccgccgccccacccgaggcg
gtcaagcggtatgcctccctgccgcatatcagcgtggcccgcaggcccgacggggccgcc
cccgggcccagcgccgacgctgcccgccgcagcagcgatggagaggcccggccactgccg
agggtggcggcaccaggcaccacgtggcgtcgcatccgggatgaggacgttccacacatc
ctgcggagcacgctgcctgccactgccctgccactgatgggcgccccgtccaaggagggc
ctcagcggccccccacagcgcaagaccagcgacgccgtggtccagacggaggactttgcc
gccactaagaccaactccagcacatctccgagtctggaaagcagggggcccccccaggcc
ccagtcagcggccccagcacactcaccagcagcgatgtggatgggcttggccccaccaaa
gcgcccacttctgctccctttgtccatgagggcctgggggtggctgcagggggctttccc
gccagccggcatggctcccccagccgctcggcccgtgtcccccccttcaactatgtgccc
agccccatggtggcagccaccactgacttggccacagagaaagcccccactgctgcccct
gccagcctcctggaatag

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (22)   
   Pfam (22)   
All databases (32)   

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